465 results about "Ferulic acid" patented technology

The invention relates to a degradable filter element and a preparation method thereof, and belongs to the technical field of PLA filter elements. The degradable filter element is arranged between an atomizing element shell and a metal heating wire, a plurality of capillary holes are formed in the degradable filter element and used for being filled with tobacco tar, and the degradable filter element is prepared from a degradable composite material through melt spinning. The degradable composite material comprises the following components: polylactic acid and modified silicon dioxide, wherein the modified silicon dioxide is prepared by taking nano silicon dioxide, a silane coupling agent, ferulic acid, amino acid and copper chloride as raw materials, the silicon dioxide is organically modified, so that the dispersity of the silicon dioxide in a polylactic acid system is improved, the interface binding force of the silicon dioxide is improved, and the mechanical property of a polylactic acid material is improved; various antibacterial components are introduced, so that the antibacterial property of the polylactic acid material can be effectively improved.

The invention provides a cronobacter malonate strain and application thereof, the strain is preserved in China Center for Type Culture Collection on January 15, 2025, the preservation date is January 15, 2025, and the preservation number is CCTCC M 2025146. The strain has excellent capability of producing 4-vinyl guaiacol, and the yield in a sorghum juice fermentation culture medium is 2.70 + / -0.15 mg / L; meanwhile, the strain can resist ferulic acid and has good capability of converting ferulic acid to generate 4-vinyl guaiacol, and when 0.1% (w / w) of ferulic acid is added into a fermentation culture medium, the content of 4-vinyl guaiacol reaches 2.68 + / -0.04 g / L. The strain is applied to production of Maotai-flavor liquor, the content of 4-ethyl guaiacol in raw liquor reaches 3.20 + / -0.26 mg / L and is remarkably increased by 223.23% (P is smaller than 0.01) compared with the content of 4-ethyl guaiacol without the strain, the Maotai flavor is prominent through sensory evaluation, the flower, fruit and burnt flavor is obvious, and the strain has important significance on improvement of the health quality of the liquor.

The invention belongs to the technical field of functional food processing, and particularly relates to a method for regulating peptide flavor and digesting characteristics by utilizing casein peptide and polyphenol self-assembly. According to the research, the casein peptide with good GABA-T inhibitory activity is taken as a raw material, and ferulic acid is added to be self-assembled with the casein peptide, so that the bitter taste of the casein peptide is reduced, and the GABA-T inhibitory activity of the casein peptide is improved in an in-vitro digestion stage. Compared with a traditional zymolyte debitterizing method, the method has the advantages that the biological activity of peptide is reserved, no toxic chemical reagent is introduced or added, and the method is safer, more efficient, more environmentally friendly and more sustainable. The method can be widely applied to functional food or health care products.

The invention discloses a lactobacillus mucus fermentation strain and application thereof, the lactobacillus mucus fermentation strain is preserved in Guangdong Microbial Culture Collection Center (GDMCC) on February 21, 2025, and the preservation number is GDMCCNO: 65936. The feruloyl esterase is separated and screened from white sour soup in Kailing in southeast of Guizhou province, has feruloyl esterase activity, and shows good blood fat reducing and fatty liver treating capabilities in a HepG2 high-fat cell model and a high-fat zebra fish model. The compound has a good prospect in the development of products for preventing or treating hyperlipidemia and fatty liver and relieving obesity.

The invention belongs to the technical field of microorganisms, and relates to a plant lactobacillus NXU-F1 strain and application thereof. The classification name of the bacterial strain is lactobacillus plantarum, the bacterial strain is preserved in Guangdong Microbial Culture Collection Center on June 20, 2025, and the preservation number of the bacterial strain is GDMCC No.66563. The invention also discloses a preparation method of the bacterial strain. The plant lactobacillus is strong in growth capability, has good adaptive capacity to environment, and can obviously increase the content of antioxidant substances when being applied to plant matrix fermentation. The lycium barbarum and grape compound fermented beverage is prepared by fermenting the lycium barbarum and grape compound fermented beverage, the content of polyphenol, flavone, polysaccharide and procyanidine in the beverage is obviously increased, and the increase of resveratrol and ferulic acid is particularly obvious; meanwhile, ester compounds are increased and aldehyde substances are reduced, so that the beverage is endowed with strong longan fruity flavor, and the flavor of harmonious sour and sweet taste and lingering aftertaste is formed.

The invention belongs to the technical field of quality control of traditional Chinese medicines, and particularly relates to a method for establishing a fingerprint spectrum of kidney-tonifying and anti-aging tablets. The establishment method of the fingerprint spectrum of the kidney-tonifying anti-aging tablet comprises the following steps: mixing the kidney-tonifying anti-aging tablet and a methanol aqueous solution, and carrying out ultrasonic treatment to obtain a test solution; reference substances in the mixed reference substance solution comprise ferulic acid, hyperoside, quercitrin, hesperidin, rosmarinic acid and salvianolic acid B; and respectively carrying out UHPLC detection on the test solution and the mixed reference substance solution, and introducing obtained chromatograms into fingerprint spectrum software for processing to obtain the fingerprint spectrum of the kidney-tonifying and anti-aging tablets. The pretreatment method is simple, and the characteristic components of the kidney-tonifying and anti-aging tablet are completely reserved; the ultra-high performance liquid chromatography is adopted, so that the precision is high, the reproducibility is good, and the stability is good; according to the fingerprint spectrum obtained by the invention, 15 common peaks are determined, so that the overall characteristics of the kidney-tonifying and anti-aging tablet can be reflected, and the quality of the kidney-tonifying and anti-aging tablet can be effectively monitored.

The present invention discloses a preparation method of a bio-based bisphenol, a bio-based epoxy resin, a preparation method thereof, and an application thereof, belonging to the field of polymer materials. The epoxy resin is obtained by condensing cheap and readily available ferulic acid, a bio-sourced diamine, and epichlorohydrin as raw materials. The epoxy resin has a simple curing process with a curing agent, high hardness, a high glass transition temperature, good heat resistance, strong toughness, and excellent mechanical properties.

The invention relates to the technical field of cosmetics, in particular to preparation and application of a cyclodextrin-coated azelaic acid oil-control skin-care product. Comprising the following steps: S1, adding deionized water into a mixer, adding a cyclodextrin-azelaic acid inclusion compound, nicotinamide and allantoin, mixing to obtain a water phase, mixing glycerol, caprylic / capric triglyceride, polydimethylsiloxane, polysorbate-80 and tocopheryl acetate to obtain an oil phase, slowly adding the oil phase into the water phase, and shearing and emulsifying to obtain a nanoemulsion; and S2, cooling the nano-emulsion, adding carbomer while stirring, continuously cooling to room temperature, sequentially adding phenoxyethanol, ferulic acid, menthol and essence, adjusting the pH value of the emulsion with triethanolamine, homogenizing, defoaming, disinfecting and filling. By adjusting the proportion of the components in the formula, the skin feeling of the product can be further optimized, so that the product is more comfortable and not greasy, and a lasting oil control effect is provided.

The invention relates to the technical field of rice bran processing, and discloses a rice bran degreasing and nutrition retention edible process synergistic treatment method which comprises the following steps: (a) in an NADES-aqueous solution medium, adding an immobilized catalyst A, and hydrolyzing ferulate bonds and phospholipids in rice bran at low temperature; (b) carrying out intermediate dehydration on the slurry obtained in the step (a) to reduce the water activity; (c) adding an immobilized catalyst B into the dehydrated slurry in the step (b), carrying out esterification reaction, and grafting free ferulic acid generated by hydrolysis to glyceride in situ; and (d) carrying out solid-liquid separation on the slurry obtained in the step (c) to obtain finished oil and finished powder. According to the method, an NADES medium is adopted to replace an organic solvent, the whole process is carried out at low temperature, degradation of heat-sensitive nutrient substances is avoided, and resource utilization of ferulic acid is achieved. The prepared functional rice bran oil is rich in feruloyl glyceride, total tocopherol and oryzanol, and is low in acid value and peroxide value.

The application discloses a squalane-based nanolipid carrier loaded with ethyl ferulate and a preparation method and application thereof. The squalane-based nanolipid carrier loaded with ethyl ferulate comprises the following components in percentage by weight: squalane 4-8%; solid oil 4-8%; ethyl ferulate 0.1-1.2%; non-ionic surfactant 1.5-5.5%; alcohol solvent 0.3-0.8%; and deionized water. The squalane-based nanolipid carrier loaded with ethyl ferulate can well load ferulate lipids, and the embedding rate is 90-97%. The particle size of the squalane-based nanolipid carrier loaded with ethyl ferulate is 100-200 nm, and the dispersion index is 0.22-0.26. The squalane-based nanolipid carrier loaded with ethyl ferulate has the advantages of simple preparation method, good particle size, dispersibility, transdermal efficiency and stability.

The invention relates to the technical field of disposable tableware, and discloses a material for paper tableware and a preparation method thereof.The preparation method comprises the steps that sugarcane fibers and bamboo fibers are pretreated to obtain a fiber mixture, and a treatment solution is collected to serve as a byproduct sugar solution; carrying out enzymolysis treatment on the fiber mixture to realize microfibrillation and release ferulic acid to obtain microfibrillated fiber pulp; fermenting and dispersing by using a byproduct sugar solution to prepare bacterial cellulose nano pulp; mixing the microfibrillated fiber pulp with bacterial cellulose nano-pulp, and carrying out enzymatic crosslinking to obtain crosslinked fiber pulp; and adding a modified sizing agent into the cross-linked fiber pulp, blending into pulp, and carrying out molding, curing, hot pressing and drying treatment to obtain the material for the paper tableware. The mechanical strength, the water resistance, the oil resistance and the thermal stability of the paper tableware material are remarkably improved, and the waste liquid load is effectively reduced.

The invention relates to the technical field of exosomes, and particularly discloses a cosmetic anti-aging mesenchymal stem cell exosome composition, which comprises a therapeutically effective amount of mesenchymal stem cell-derived exosome, the functional carrier comprises a transdermal absorption enhancer and an antioxidant stabilizer; at least one synergistic active component selected from the group consisting of small molecule peptides, plant-derived antioxidants, hyaluronic acid or derivatives thereof; the small molecule peptide is one of oligopeptide-1 and palmitoyl tripeptide-5; the plant source antioxidant is one of resveratrol and ferulic acid; wherein the exosome and the synergistic active component are compounded through a phospholipid bilayer fusion technology; through a phospholipid bilayer fusion technology, the mesenchymal stem cell exosome and a synergistic active component are directionally compounded, an exosome membrane structure is used as a natural carrier, the active component is effectively prevented from being degraded, and meanwhile, the bioavailability is improved by utilizing the targeting property of the exosome membrane structure.

The invention discloses a tetrandrine ferulate and its application in the preparation of a medicament for treating pulmonary fibrosis. The pharmacological effects of tetrandrine and ferulic acid, as well as those after salification, are studied. It is found that both have an anti-pulmonary fibrosis effect, and the two can be used in combination to synergistically exert a more excellent anti-pulmonary fibrosis efficacy. At the same time, the solubility of tetrandrine can also be increased. This has not been reported in existing literature. The tetrandrine ferulate of the present invention has lower cytotoxicity, and the cell viability of normal human liver cells LO-2 and human embryonic fibroblasts MRC-5 is higher than that of tetrandrine, which alleviates the burden of liver and lungs to a certain extent and has good safety.

The invention relates to the technical field of high polymer materials, in particular to an anti-aging thread gluing material and a preparation process thereof. Comprising the following steps: preparation of aluminum-doped zinc oxide, tannic acid modified aluminum-doped zinc oxide, ferulic acid modified nylon fiber and modified nylon master batch preparation of the thread gluing. According to the invention, groups of tannic acid and aluminum ions and zinc ions of aluminum-doped zinc oxide are driven by heat energy of a reflux reaction to simultaneously generate chelation-dehydration condensation to form a five-membered ring chelate, so that a compact coating layer is formed on the surface, and the coating layer is simple in component and has very stable chemical bonds; the ultraviolet light stability of aluminum-doped zinc oxide is enhanced, the layer can generate hydrogen bond / pi-pi interaction with nylon amido bonds, the interface bonding strength is improved, the particle size is kept at the level of no filter pressure fluctuation in the spinning process, and the volume resistivity of nylon fibers is reduced.

The invention provides a donkey-hide gelatin solid beverage and a preparation method thereof, the preparation method comprises the following steps: adding 8 times by mass of water into rhizoma polygonati, Chinese wolfberry, astragalus membranaceus, codonopsis pilosula, red dates, angelica sinensis and orange peel, soaking for 0.5 h, extracting for 2 h for the first time, adding 6 times by mass of water for extracting for 1.5 h for the second time, combining filtrates, and concentrating until the relative density is 1.23 g / cm < 3 > to obtain a water extraction concentrated solution; mixing the water extraction concentrated solution with maltodextrin, and drying to obtain an extract; and adding auxiliary materials into the extract and the donkey-hide gelatin, and molding to obtain the donkey-hide gelatin solid beverage. In the extraction step, proper soaking time, water adding amount and extraction time are combined, so that the ferulic acid content, the total polysaccharide content, the hesperidin content and the calycosin-7-glucoside content in the concentrated solution are all higher. And on the basis, subsequent drying and forming are carried out, so that the final donkey-hide gelatin solid beverage also has relatively high content of the components, and the content in each batch of products is stable.

The invention discloses application of salvianolic acid A in preparation of a medicine for preventing and treating vulnerable plaques of advanced atherosclerosis. The invention also discloses application of the salvianolic acid A combined with ferulic acid or the salt thereof in preparation of drugs for preventing and treating advanced atherosclerosis vulnerable plaques. Researches find that salvianolic acid A can promote apoptosis of senescent vascular smooth muscle cells and has a Senlytics effect; the salvianolic acid A stabilizes vulnerable atherosclerotic plaques by reducing the load of senescent vascular smooth muscle cells; the salvianolic acid A is in non-covalent binding with ASP54, ALA55, LYS58, ASP93, ASP102 and LYS112 of the HSP90AA1 to play a role in inhibition, and the ASP93 has the greatest contribution to binding free energy. The research of the invention is of great significance to the development and application of drugs with anti-aging effect for stabilizing advanced atherosclerotic vulnerable plaques.

The present invention relates to a recombinant organism or microorganism having a decreased pool of crotonic acid compared to the organism or microorganism from which it is derived due to at least one of: (i) an increased conversion of crotonyl-CoA into butyryl-CoA; and / or an increased conversion of butyryl-CoA into butyric acid; (ii) an increased conversion of crotonyl-CoA into 3-hydroxybutyryl-CoA; and / or an increased conversion of 3-hydroxybutyryl-CoA into 3-hydroxybutyric acid; (iii) an increased conversion of crotonic acid into crotonyl-CoA; (iv) an increased conversion of crotonyl-[acyl-carrier protein] into butyryl [acyl-carrier-protein]; (v) a decreased conversion of crotonyl-CoA into crotonic acid; and / or (vi) a decreased conversion of crotonyl-[acyl-carrier protein] into crotonic acid. Moreover, the present invention relates to the use of such a recombinant organism or microorganism for the production of alkenes with the enzyme ferulic acid decarboxylase. Further, the present invention relates to a method for the production of isobutene or butadiene by culturing such a recombinant organism or microorganism in a suitable culture medium under suitable conditions.

The invention discloses a pharmaceutical composition, which comprises chlorogenic acid, ferulic acid and a zeolite imidazole framework material, the mass ratio of chlorogenic acid to ferulic acid is 4: 1-1: 4, and the zeolite imidazole framework material is a Zn-based zeolite imidazole framework material. In the composition, the compatibility of chlorogenic acid and ferulic acid can synergistically regulate the proliferation, migration and apoptosis of keratinocytes, and restore the physiological function imbalance of human skin keratinocytes caused by EGFRIs. The ZIF can efficiently carry chlorogenic acid and ferulic acid together, the nanoscale particle size of the ZIF is beneficial to permeation of the medicine into the skin, and hydroxyl on the surface of the ZIF and ceramide in the skin are subjected to hydrogen-bond interaction to retain the medicine at the focus position. The composition preparation disclosed by the invention is good in moisturizing performance and simple and convenient to use, and can be used for effectively treating skin toxic reactions such as pustule type rash, skin dryness and itching, perionychomycosis, abnormal hair regeneration and the like caused by EGFRIs.

The invention relates to the technical field of bioengineering, in particular to a preparation process for extracting antihypertensive peptide from euphausia superba. The process comprises the following steps: adding a ferulic acid / arginine double-grafted pullulan compound in a preparation process, and breaking an emulsification interface by utilizing beta-cyclodextrin adsorption and phospholipase A2 cracking to obtain a soluble pretreatment product; meanwhile, short-time round-trip pH pulse is implemented in the incision enzyme hydrolysis process to activate potential enzyme cutting sites, finally, hydrophobic aggregation peptides are removed through weak acid rapid elution, and excision hydrolysis is performed to obtain a target product with the molecular weight of 0.5-3 kDa, so that dynamic induction and antioxidant steady-state dual control of hydrolysis reaction is realized; the generation proportion of short peptides and the ACE inhibition persistence are improved, and the flavor and the storage stability are remarkably improved. The method is controllable in technological process, high in repeatability and suitable for large-scale preparation of the euphausia superba protein functional peptide and development and application of antihypertensive food.

The invention relates to the technical field of cosmetics, and discloses a herbal probiotic composition with whitening and anti-aging effects and a preparation method thereof. The herbal probiotic composition is prepared from alpha-arbutin, licoflavone, bakuchiol, resveratrol, ellagic acid, a metagen complex, skin micro-ecological prebiotics, sodium phytate, ferulic acid, rosemary polyphenol, polycystic liposome and the balance of a carrier suitable for skin. The herbal probiotic composition disclosed by the invention realizes stable co-delivery of hydrophilic and lipophilic activities and effective retention of cuticles under mild pH, synergistically inhibits blackness, resists oxidation and supports microecology, and improves the effective content and batch-to-batch consistency in the shelf life through metal ion accessibility control, so that the whitening and anti-aging effects are improved.

The invention relates to the technical field of beverage processing, in particular to a corn juice compound beverage and a preparation method thereof. The feed comprises the following raw materials: corn, black rice, oat, carrots, corncob powder, orange peel, compound enzyme, beta-cyclodextrin, Arabic gum, inulin, a yeast extract, monopotassium phosphate, vitamin B and compound strains. The compound enzyme seed is prepared from the following components: alpha-amylase, pullulanase, tannase and neutral protease; the composite strain is prepared from the following components: saccharomycetes, lactobacillus plantarum and monascus purpureus. According to the corn juice composite beverage and the preparation method thereof, through multi-dimensional synergistic interaction, the beverage realizes a layering flavor with both freshness, fruity flavor and cereal sweetness and fragrance, an anti-oxidation network constructed by polyphenol, carotenoid and ferulic acid and an intestinal tract nursing effect brought by complementation of soluble-insoluble fibers form the corn juice composite beverage with functional value and sensory experience.

This invention discloses a composite microbial agent with both efficient ferulic acid degradation and growth-promoting functions, and its preparation method. The active component of this composite microbial agent contains *Pseudomonas soybeanii* with accession number CGMCC No. 36468. Pseudomonas soyae Strain A9, and *Pseudomonas aeruginosa* with accession number CGMCC No. 36469. Paraburkholderia oxyphila Strain A23. This invention, by screening and combining two functionally complementary strains, fundamentally solves the technical problems of existing single-strain ferulic acid degrading bacteria agents having limited function and unstable field application efficacy, achieving improved degradation efficiency and synergistic growth promotion effects.

The invention discloses antibacterial mouthwash as well as a preparation method and application thereof, and belongs to the technical field of daily chemical products. According to the invention, egg white lysozyme, ferulic acid and grape seed procyanidine are taken as core components, and the mouthwash with an efficient bacteriostatic effect is developed. And the antibacterial rates of streptococcus mutans and porphyromonas gingivalis are 96.88% and 96.30% respectively. Researches show that bacterial biofilms can be destroyed by using the mouthwash, and the biofilm quantity is reduced by 53.7% after the bacterial biofilms are treated for 24 hours; extracellular polysaccharide is inhibited, the content of water-insoluble glucan is reduced by 62.3%, and synthesis of a key cariogenic matrix is hindered; the acid production capacity is regulated and controlled, the pH change of 24-hour culture is only 1.50, and xylitol competitively inhibits glycolysis and cooperates with ferulic acid to block bacterial metabolism. The mouthwash prepared by the invention avoids the problem of enzyme activity inhibition of the ionic surfactant of the traditional mouthwash, takes effect more quickly, and provides a basis for developing natural, safe and efficient functional mouthwash.

The invention discloses application of high-ferulic acid whole wheat flour food in preparation of products for prolonging life of animals. According to the method, corn flour, whole wheat flour and refined flour are used as raw materials to prepare fruit fly culture media of materials with different ferulic acid content differences, and then different culture media are used for feeding fruit flies under oxidative damage, high-temperature stress and natural aging models. The method comprises the following steps: respectively obtaining survival curves corresponding to culture mediums with different ferulic acid contents for feeding drosophila melanogaster under different models, and analyzing to find that compared with a culture medium with low ferulic acid whole wheat flour and a culture medium with low ferulic acid fine flour, the survival curves of the culture mediums with different ferulic acid contents are different; by feeding the high-ferulic acid whole wheat flour culture medium and the corn flour culture medium, the resistance of the fruit flies to oxidative damage, high-temperature stress and natural aging is enhanced, and the median survival time and the maximum survival time of the fruit flies are remarkably prolonged. It is found for the first time that the ferulic acid content in food is related to senescence delaying, and the method has important significance in developing anti-senescence products.

The application discloses a multifunctional biomaterial with light protection and repair functions, which comprises the following components in percentage by mass: 4-8% of methacrylated gelatin, 0.5-2% of nanomicelles of ferulic acid, 0.5-1% of adhesive peptides, 0.5-1.5% of hyaluronic acid and 0.5-1% of ekdromicin. The application further discloses a preparation method of the multifunctional biomaterial and application thereof. The multifunctional biomaterial realizes a trinity synergistic effect of 'protection-repair-regeneration', target enrichment of active ingredients to damaged parts, and can stimulate vascular regeneration, improve skin microcirculation, has antioxidant, anti-inflammatory and healing functions, and promotes repair of light-damaged skin.

This invention belongs to the field of genetic engineering technology, specifically relating to an engineered bacterium that efficiently synthesizes curcumin using ferulic acid as a precursor, its construction method, and its application. This invention enhances ferulic acid uptake and precursor supply capabilities from the source by knocking out the fdc and mcrC genes and overexpressing the tnaT and accD genes. Furthermore, it achieves high-level stable expression of exogenous key enzyme genes DCS and CURS through codon optimization. Combined with the synergistic effect of a two-stage fermentation regulation process, a stepwise increase in ferulic acid conversion rate is achieved. In a fermentation system with an initial ferulic acid concentration of 5 g / L, the conversion rate of the recombinant strain of this invention increased from 28.6% to 55.2% compared to the unoptimized strain, and further reached 80.2% after fermentation process optimization. Simultaneously, it effectively inhibits the formation of the byproduct 4-vinylguaiacol, significantly improving the utilization rate of ferulic acid and reducing the raw material cost of curcumin biosynthesis.

A method to produce a mixture comprising poacic acid (X) and poacidiene (Y) and the resulting product-by-process. The method includes the steps of subjecting a solution of ferulic acid to a free-radical coupling reaction to yield an intermediate mixture comprising ferulic acid dehydrodimers and decarboxylating the intermediate mixture to yield a product mixture containing poacic acid (X) and poacidiene (Y).

The present application relates to the technical field of bacteriostatic drugs, and particularly relates to application of traditional Chinese medicine monomers in preparation of bacterial efflux pump AcrB inhibitor or antibiotic activity improving drug and combined bacteriostatic composition. The traditional Chinese medicine monomers include red cedar flavone, stigmasterol, trichosanthin diol-3-benzoic acid ester, glycyrrhizic acid, alpha-bosanol, agastachin, acaciin, triptonylline C, rhein acid diglucoside, brassicasterol ferulate, cholesterin ferulate or calophyllolide G. The traditional Chinese medicine monomers can inhibit the efflux activity of AcrB, so that the drug molecules entering the bacteria continuously accumulate, thereby recovering the bactericidal efficiency of the existing antibacterial drugs and reducing the drug resistance of bacteria to the antibacterial drugs.

The invention relates to the technical field of traditional Chinese medicine pharmacy, and discloses a preparation method of a traditional Chinese medicine external preparation for arthralgia based on blood circulation promoting and blood stasis removing, which comprises the following steps: extracting ferulic acid from angelica sinensis and ligusticum wallichii by adopting a supercritical CO2 fluid extraction process; extracting safflower, frankincense and other medicinal materials to obtain a synergistic active ingredient extract; the ferulic acid is used as a first hydrogen bond donor to react with lauric acid used as a temperature-sensitive phase change hydrogen bond donor and choline chloride used as a hydrogen bond acceptor, and the temperature-sensitive bioactive ternary eutectic solvent is prepared; loading the synergistic active ingredient extract in the solvent at low temperature to form a medicine mother solution; and finally, mixing the medicine mother liquor with auxiliary materials to prepare the external preparation. Ferulic acid in medicinal materials serves as a structural unit of a functional solvent, the solvent prepared under the mild condition has biological activity and temperature-sensitive phase change characteristics, a medicine storage cavern can be formed on the skin surface in situ, long-acting slow release and efficient transdermal absorption of active ingredients are achieved, and the curative effect and safety of a preparation are improved.

The invention relates to a method for preparing cement clinker from magnesium slag and carbide slag, and belongs to the technical field of cement materials.The cement clinker is prepared from carbide slag, modified magnesium slag, activated converter slag and coal gangue as main raw materials, the modified magnesium slag is an Mg3 (PO4) 2 protective layer formed by ball-milling modification of magnesium slag through a Mg (H2PO4) 2 aqueous solution and a ferulic acid ethanol solution, and the magnesium slag is a magnesium slag protective layer formed by ball-milling modification of activated converter slag and coal gangue. The activated converter slag is obtained by roasting and activating the converter slag and Na2CO3; the four raw materials are mixed according to a certain proportion, a Li2B4O7-CaF2 composite mineralizer is added for low-temperature calcination, a proper amount of SO2 is introduced to induce generation of a new three-phase system of gehlenite-dicalcium silicate-spinel, carbon emission can be effectively reduced, fuel energy consumption can be saved, and the obtained cement clinker has high early strength and can be widely applied to the field of cement materials. The early strength and the later strength stability are well balanced, cracking is not prone to occurring, and the sulfate corrosion resistance is excellent.