1450 results about "Ferulic acid" patented technology

Personal care compositions containing an active selected from the group consisting of phlorogine, phlorgine BG, deoxyArbutin, sucrose dilaurate, bakuchiol, pyrenoine, millet, arlatone dioic acid, cinnamic acid, ferulic acid, achromaxyl, methyl nicotinamide, oil soluble licorice extract, folic acid, undecylenic acid, zinc undecylenate, L-tryptophan, thiamine HCl, hexylresorcinol, lipidami red vine, dragosine, methyl gentisate, inositol, symdiol 68, laminaine, their salts, their derivatives, their precursors, and / or combinations thereof. Methods for regulating the condition of mammalian keratinous tissue by topically applying the personal care compositions are also provided.

The invention provides a preparation method of a yin tonifying and calming tablet, which is prepared from crude drugs including 75g of angelica sinensis, 57g of radix ophiopogonis, 48g of schisandra chinensis, 39g of vine of multiflower knotweed, 39g of rhizome rehmanniae, 75g of poria cocos, 18g of platycladi seed, 75g of codonopsis pilosula, 93g of concha margaritiferausta, 57g of radix scrophulariae, 57g of salvia miltiorrhiza, 39g of polygala tenuifolia, 39g of platycodon grandiflorum and 10.2g of cinnabar through supercritical extraction and microwave extraction, so that the content of ferulic acid is greatly improved. The invention also provides the application of the yin tonifying and calming tablet in preparing a medicine for restraining proliferation of mice leukemia cell, L1210 cell.

A microbiological process for producing vanillin and other useful products from ferulic acid is disclosed. Vanillin and guaiacol are recovered from the process using a differential pH extraction where the guaiacol is recovered at a pH of greater than 9 and the vanillin is recovered at a pH of from about 5 to about 8.

The present invention provides a technique method which separates lignose, hemicellulose, cellulose and phenolic acid from lignocellulosic biomass. Under the selected pH value and temperature, the lignocellulosic biomass is processed by hot water, so that the hemicellulose and the phenolic acid are preferentially resolved in aqueous solution, delignification processing is carried out, organic solvent or alkaline solution is applied to carry out high-temperature cooking, the generated liquid-solid phase product can be easily and effectively separated, and thus the hemicellulose, the cellulose and the phenolic acid can be respectively obtained. Moreover, enzymatic treatment can be selectively added, and a solid phase product is obtained at the first stage of a group of enzymatic treatment with a cooperative effect. Because the ferulic acid linkage between the hemicellulose and the lignose can be selectively broken, the separation of the chemical components has a high yield rate and high purity.

The present invention relates to cosmetic compositions containing resveratrol ferulate in a topically acceptable carrier. Such compositions are particularly effective for skin lightening and anti-aging applications and have excellent color stability and extended shelf life.

Dry milling methods for preparing oat products enriched in the content of β-glucan and methods for preparing foodstuffs incorporating such an enriched oat product especially ready-to-eat cereals are provided. Heat conditioned dehulled oats are dry milled to form a coarse whole non defatted oat flour and then, without a preceding removal of fat, dry fractionated into coarser bran and finer oat flour fractions at multiple stages. The coarse oat flour is first dry classified to separate or form a coarser fraction oat bran containing more concentrated β-glucan and a finer oat flour or starch containing or endosperm containing fraction. The oat bran is subjected to second and third rounds of milling and classification to form a high β-glucan content (>7-9%) oat bran and a low β-glucan content (3%) oat flour. The methods are low cost and commercially practical. Preferably, the high β-glucan content oat bran and oat flour fractions can have a syringic acid to ferulic acid ratio of at least 2.5:1 indicating improved flavor. Preferably, the oat bran and oat flour have a Farinograph value of 5 to 20 minutes indicated partial gelatinization. The oat bran and oat flours can be used to prepare foodstuffs such as ready-to-eat cereals.

The invention discloses nutritional health-care fine dried noodles which are developed with suaeda salsa, stigma maydis and Chinese herbal medicines such as the root of kudzu vine, gynostemma pentaphyllum, cortex phellodendri, dandelions, cornus officinalis, radix rehmanniae preparata, herba portulacae, herba houttuyniae, licorice root and stevia rebaudiana as raw materials and have the effects of reducing blood lipid and blood pressure, improving organism immunity, beautifying the face and clearing away toxins, resisting fatigue and the like. The fine dried noodles contain rich functional activated substances such as suaeda salsa and amino acid, polypeptides, water-soluble dietary fibers, ferulic acid, active polysaccharides, saponin and flavone in the Chinese herbal medicines. The fine fried noodles have the advantages that compatibility of suaeda salsa and the Chinese herbal medicines is scientific, functional components in the Chinese herbal medicines are extracted through the technologies including ultrasonic secondary crushing, enzymolysis combined compound microorganism degradation and microwave assisted extraction method, the content of organic selenium in the product is increased, the nutritional healthy functions of the product are remarkably improved, and market prospects are wide.

The present invention is one Streptomyces strain and the process of utilizing the Streptomyces strain in converting ferulic acid to produce high concentration vanillin. The Streptomyces strain is Streptomyces sp.V-1 in the preservation number of CCTCC M 206065. In the GY converting culture medium with the Streptomyces strain, ferulic acid may be converted to produce high concentration vanillin fermenting liquid. Adding macroporous adsorption resin DM11 into the converting culture medium can increase the concentration of vanillin fermenting liquid greatly. The present invention has the advantages of less environmental pollution, high product concentration, less side products, short production period, low cost, etc.

The invention discloses a process for separating and extracting natural ferulic acid with the content not more than 98% from wastes in rice bran oil processing. The process is characterized in that the wastes generated in the rice bran oil processing method are used as raw materials; the process comprises the following steps of: washing by using alcohol, saponificating and filtering, acidifying and filtering, dissolving by using alcohol and filtering, refining by using ion exchange resin, decoloring, concentrating, pumping and filtering, and drying by vacuum to obtain the white powder product with the natural ferulic acid content not more than 98%. The invention has the advantages of easy obtainment of raw materials, utilization of wastes, simple and process, high purity of product by more than 98%, and industrial production.

The invention discloses whitening cosmetic and a preparation method thereof. A composition of a plurality of plants is taken as a main raw material, and the whitening cosmetic mainly comprises the following components: a rice bran extract, a rhodiola rosea extract, a ginkgo leaf extract, tea polyphenol, a lemon juice concentrated liquor, chitosan, a puerarin extract, konjac powder, a sunflower faceplate extract, a sunflower seed extract, a saponin kernel, hemicelluloses and honey. In addition, the whitening cosmetic also contains the following raw materials: a little of glycerinum, 1,3-propylene glycol, squalane, sodium hyaluronate, carbomer, triethanolamine, triethanolamine, allantoin, nanometer titania, collagen powder, an antibacterial agent, a ferulic acid isooctyl ester and glutathione. The composition can be applied to a whitening formula, has the effects of whitening the skin, moisturizing, resisting bacteria and diminishing inflammation, removing free radicals, inhibiting melanin formation, and inhibiting hallachrome mutase and tyrosinase activity.

The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension. The agent for preventing, improving or treating hypertension contains the following components (A) and (B): (A) a compound selected from the group consisting of caffeic acid, chlorogenic acid and ferulic acid, and esters and pharmaceutically acceptable salts thereof; and (B) a component selected from the group consisting of central nervous system stimulating components, food fibers, extracts of perennial evergreen leaves of the genus Camellia, Theaceae, or Eucommia ulmoides Oliver, Eucommiae, organic acids having a molecular weight of 60 to 300 (excluding citric acid) and pharmaceutically acceptable salts thereof, and sugar alcohols.

The invention relates to an action of ferulic acid on enhancing the drug effect of some medicaments and a purpose thereof, wherein the medicaments mainly comprise alkaloid medicaments including matrine, kushenin, sophocarpine, hyoscyamine, narceine, hanfangchin A, jamaicin, morphine, codeine, evodiamine, strychnine, catharanthine, vincristine, taxol, verticine, peimine, peiminine, ephedrine, pseudoephedrine, wilfordine, triptolide, tripdiolide and the like, and flavonoid medicaments including puerarin, ginsenoside, ginsengenin, mangiferin, scutelloside, alkannin, meletin, rutin, hesperidin, daidzin, soybean isoflavone, daidzein, carthamin, catechin and the like. The ferulic acid and the medicaments can form a compound or a medicament compound, or the ferulic acid and the medicaments can generate a chemical reaction (including salification, esterification, amidation, ketonization, etherification and the like), and / or the ferulic acid and the medicaments can generate a synergistic effect and an additive effect.

The invention specifically discloses composite whitening and banishing essence and a preparation method thereof. The composite whitening and banishing essence comprises the following raw materials in percent by weight: 1 to 25 percent of Chinese herb active site extract, 0.1 to 10 percent of ethylhexyl ferulate, 0.1 to 5 percent of vitamin C ethyl ether, 0.05 to 3 percent of nicotinamide, 10 to 40 percent of grease, 1 to 6 percent of emulsifier, 1 to 15 percent of moisturizing agent, 0.1 to 1.5 percent of preservative, 0.1 to 0.5 percent of essence and the balance of deionized water. By virtue of the composite whitening and banishing essence, the activity of tyrosinase can be effectively inhibited, oxygen free radicals are efficiently eliminated, forming of melanin is prevented, and the formed melanin is decomposed and faded; meanwhile, an endocrine system of a human body can be regulated, and injuries to the skin caused by chemical components such as hormone are repaired, so that effects of treating both symptoms and root causes comprehensively and quickly are achieved.

The invention relates to a ferulic acid shown in a general formula (I) and the application of derivatives thereof to pesticides. When used as novel anti-phytoviral agents, the derivatives can well inhibit tobacco mosaic viruses, pepper viruses, tomato viruses, sweet potato viruses, potato viruses, melon viruses, maize dwarf mosaic viruses and the like, and effectively prevent and control the virus diseases of various crops such as tobacco, peppers, tomatoes, melons, grains, vegetables, beans and the like, and are particularly suitable for preventing and controlling tobacco mosaic. Meanings of each group are shown in specifications.

The invention relates to a quality detection method of a traditional Chinese medicine preparation. The method comprises the following steps: respectively taking gallic acid, albiflorin, paeoniflorin,ferulic acid, liquiritin, beta-ecdysterone, senkyunolide I, glycyrrhizin, cinnamic acid, cinnamyl aldehyde, paeonol, ammonium glycyrrhizinate and ligustilide as reference substances, and establishinga fingerprint spectrum of the traditional Chinese medicine preparation by adopting high performance liquid chromatography; identifying Chinese angelica, the rhizome of chuanxiong, radix paeoniae alba,moutan bark, ginseng, cassia bark, licorice root and the root of bidentate achyranthes of the traditional Chinese medicine preparation by adopting thin-layer chromatography. The traditional Chinese medicine preparation is prepared by using the following raw materials: Chinese angelica, the rhizome of chuanxiong, radix paeoniae alba, cassia bark, moutan bark, zedoray rhizome, ginseng, licorice root and the root of bidentate achyranthes. With the two detection ways, comprehensive quality evaluation can be conducted on the meridian-warming decoction traditional Chinese medicine preparation. Themethod is simple, convenient, high in accuracy and high in reproducibility; a scientific basis can be provided for quality detection and evaluation of the meridian-warming decoction traditional Chinese medicine preparation, and the product quality is effectively controlled.

The invention relates to a cross-linked body of Tacrine and ferulic acid or a dynamic isomer, medicine salts, a pro-drug or a solvate thereof, wherein, the structural formula is shown in formula (I). The invention also relates to a method for making the same, a combination taking the formula (I) compound as active composition, and application of the compound and the combination thereof taken as the medicine for preventing and curing AChE-mediated diseases, in particular the application in preparation of the medicine for preventing Alzheimer diseases and dementia, in which other oxidative stresses take part.

A feed additive composition comprising a direct fed microbial (DFM), in combination with a xylanase (e.g. endo-1,4-β-d-xylanase) and a β-glucanase (and optionally a further fibre degrading enzyme), wherein the DFM is selected from the group consisting of an enzyme producing strain; a C5 sugar-fermenting strain; a short-chain fatty acid-producing strain; a fibrolytic, endogenous microflora-promoting strain; or combinations thereof. The DFM may be selected from the group consisting of: Bacillus subtilis AGTP BS3BP5, Bacillus subtilis AGTP BS442, B. subtilis AGTP BS521, B. subtilis AGTP BS918, Bacillus subtilis AGTP BS1013, B. subtilis AGTP BS1069, B. subtilis AGTP 944, B. pumilus AGTP BS 1068 or B. pumilus KX11-1, Enterococcus faecium ID7, Propionibacterium acidipropionici P169, Lactobacillus rhamnosus CNCM-1-3698, Lactobacillus farciminis CNCM-1-3699, a strain having all the characteristics thereof, any derivative or variant thereof, and combinations thereof and the further fibre degrading enzyme may be selected from the group consisting of a cellobiohydrolase (E.C. 3.2.1.176 and E.C. 3.2.1.91), a β-glucosidase (E.C. 3.2.1.21), a β-xylosidase (E.C. 3.2.1.37), a feruloyl esterase (E.C. 3.1.1.73), an α-arabinofuranosidase (E.C. 3.2.1.55), a pectinase (e.g. an endopolygalacturonase (E.C. 3.2.1.15), an exopolygalacturonase (E.C. 3.2.1.67) or a pectate lyase (E.C. 4.2.2.2)), or combinations thereof.

The invention relates to application of a ferulic acid derivative to preparation of drugs for treating and / or preventing neurodegenerative diseases related to nerve cell injury. The neurodegenerative diseases includes but not limited Alzheimer's disease, vascular dementia, Parkinson's disease, multiple sclerosis, diabetic neuropathy, ischemia stroke and hemorrhagic stroke.

A composition for modulating cytokines to regulate an inflammatory or immunomodulatory response. The composition can include at least one of rosehips, blueberry, blackberry, elderberry, cranberry, rosemary, clove, feverfew, nettle root, artichoke, reishi mushroom, olive extract, green tea extract, grape seed extract, resveratrol, Aframomum melegueta, boswellia serrata extract, boswellia forte, ipriflavone, tocotrienols, evening primrose oil, INM-176, borage oil, krill oil, at least one type of xanthophyll (e.g., astaxanthin), green coffee extract and ferulic acid. Specifically, a composition of the invention can include: rosehips and at least one of blackberry, blueberry, elderberry, and optionally krill oil; or rosehips, resveratrol and at least one of Aframomum melegueta and astaxanthin. Based on the cytokine modulation and cytokine response inhibition of the composition, it can be used to regulate an immunomodulatory and / or inflammatory response, and subsequently treat diseases and / or abnormal conditions associated with inflammatory response, for example, cardiovascular conditions, arthritis, osteoporosis and Alzheimer's disease.

The invention provides a method for preparing Bailing tablets. The Bailing tablets are prepared from 194g of Chinese angelica, 42g of pseudo-ginseng, 83g of safflower, 167g of peony bark, 83g of peach kernel, 167g of divaricate saposhnikovia root, 167g of atractylodes, 42g of angelica root, 417g of purslane, 83g of red peony root and 194g of astragalus root serving as raw medicaments by adopting supercritical extraction and microwave extraction, so that the ferulic acid content is greatly improved. The invention also provides application of the Bailing tablets in preparation of a medicament for inhibiting propagation of human histiocytic lymphoma U937 cells.

Personal care compositions containing an active selected from the group consisting of phlorogine, phlorgine BG, deoxyArbutin, sucrose dilaurate, bakuchiol, pyrenoine, millet, arlatone dioic acid, cinnamic acid, ferulic acid, achromaxyl, methyl nicotinamide, oil soluble licorice extract, folic acid, undecylenic acid, zinc undecylenate, L-tryptophan, thiamine HCl, hexylresorcinol, lipidami red vine, dragosine, methyl gentisate, inositol, symdiol 68, laminaine, their salts, their derivatives, their precursors, and / or combinations thereof. Methods for regulating the condition of mammalian keratinous tissue by topically applying the personal care compositions are also provided.

The invention relates to the technology for preparing ferulic acid and phytic acid from rice bran as raw materials through alkali liquid extraction separation. The ferulic acid extraction process is characterized in that high-purity ferulic acid is obtained through purification and separation by a high-speed reverse flow chromatography method. The phytic acid extraction process is characterized in that the ultrasonic auxiliary extraction and macroporous absorbent resin technology is adopted for preparing the phytic acid. The high-speed reverse flow chromatography method is used for preparing the erulic acid, so the invention has the characteristics of large separation amount, no sample loss, high efficiency, high speed, mild separation environment, solvent saving and the like. In the ultrasonic extraction of the phytic acid, the production time is shortened. When the technology is used for producing the ferulic acid and the phytic acid, the product purity is high, the quality is high, and the industrialization can be easily realized.

The invention discloses livestock and poultry feed added with germinated brown rice, which is characterized in that 1.3-3.2g of germinated brown rice powder is added into livestock and poultry feed per kilogram, and the germinated brown rice per hectogram contains 500-600mg of gamma-aminobutyric acid (GABA). The gamma-aminobutyric acid is replaced with the germinated brown rice in the invention; and the germinated brown rice contains abundant energy substances, protein and lipid oxidation resistant substances, such as inositol, ferulic acid, tocopherol, tocotrienol, oryzanol, phytic acid and the like in addition to providing GABA and contains abundant mineral substance elements and vitamin, such as calcium, magnesium, ferrum, zinc, vitamin B1, vitamin B2, vitamin E, niacin, pantothenic acid and the like. The livestock and poultry feed is better for the growth and development of animals.

The invention discloses concrete flavouring for tobacco and a preparation method and application thereof, belonging to the technical field of additive for tobacco. In the invention, waste tobacco used as raw material is sequentially fermented with rhodococcus, bacillus pumilus and bacillus subtilis to reduce nicotine in the waste tobacco and convert ferulic acid in the tobacco into incense ingredients such as 4-guaethol and vanillin; after fermentation is finished, the conventional biochemical technology is utilized to extract the incense ingredients from the waste tobacco for preparing concrete flavouring. The concrete flavouring obtained by invention contains the following main incense ingredients with higher contents: benzyl alcohol, solanone, vanillin, BETA-damascenone, dihydroactinidiolide, megastigmatrienone, duvatriene diglycol and neophytadiene. Results of an aromatic flavouring smoke panel test show that the concrete flavouring has obvious effects of increasing tobacco aroma,smoothing alcohol and smoke, reducing irritation, covering impurity gas and improving smoking taste of cigarettes.

The invention discloses an ultrasound-assisted enzymolysis wheat bran method for preparing ferulic acid, comprising the following steps: a. crushing wheat bran; b. heating wheat bran obtained in step (a) in water bath; c. removing starch in wheat bran by enzymolyzing alpha-amylase; d. removing protein in wheat bran by using alkaline protease; e. centrifugally precipitating suspending liquid, abandoning supernatant, and washing the suspending liquid with distilled water to obtain bran residue; f. drying bran residue; g. carrying out ultrasound treatment on dried wheat bran; h. carrying out enzymatic reaction on bran obtained in step g by xylanase; and i. centrifuging suspending liquid obtained in step (h) by enzymatic reaction, taking supernatant, after washing residue at the lower level, combining supernatant to carry out concentration and vacuum drying to obtain crude ferulic acid; dissolving the crude product in anhydrous ethanol, centrifuging to remove precipitation and obtaining transparent faint yellow supernatant, and then concentrating and drying to obtain ferulic acid crystallization with higher purity.

The invention discloses a thermostable carboxylesterase gene, coding protein and application thereof, the esterase has amino acid sequence shown in SEQ ID NO:1. Compared with the prior art, the esterase containing EstW is thermostable esterase obtained from streptomycete in known mesophilic bacteria, can be widely applied to production of non-steroidal anti-inflammatory drugs or ferulic acid.

Processes for isolating bitter quinides for use in food and beverage products entailing contacting a bitter quinide solution with an adsorbent to adsorb bitter quinides from the bitter quinide solution, desorbing the bitter quinides from the adsorbent to obtain a bitter quinide isolate, and adding the bitter quinide isolate to a food or beverage product to enhance the flavor thereof. A bitter quinide isolate made up of at least one of 3-O-caffeoyl-γ-quinide, 4-O-caffeoyl-γ-quinide, 5-O-caffeoyl-epi-δ-quinide, 5-O-caffeoyl-muco-γ-quinide, 3-O-feruloyl-γ-quinide, 4-O-feruloyl-γ-quinide, 3,4-O-dicaffeoyl-γ-quinide, 4-O-caffeoyl-muco-γ-quinide, 3,5-O-dicaffeoyl-epi-δ-quinide, 4,5-O-dicaffeoyl-muco-γ-quinide, 5-O-feruloyl-muco-γ-quinide, 4-O-feruloyl-muco-γ-quinide, 5-O-feruloyl-epi-δ-quinide, quinide esterified with one or more of caffeic acid, ferulic acid, p-courmaric acid, 2,4-dimethoxycinnamic acid and mixtures thereof.

The invention provides a method for simultaneously detecting main components of paeoniflorin, beta ecdysterone, laetrile, mulberroside A, caffeic acid, ferulic acid, salvianolic acid B, astragaloside, formononetin, cryptotanshinone and tanshinone IIA of a Naoxintong capsule in a plasma sample by a liquid chromatography-tandem mass spectrometry (HPLC-MS / MS). In a liquid chromatogram, a mobile phase consists of acetonitrile and a formic acid aqueous solution of which the volume fraction is 0.1%, and gradient elution is used. A mass spectrum uses a quick positive and negative ions switching and analyzing mode and an MRM (Multiple Reaction Monitoring) scanning manner. After the Naoxintong capsule is taken, the situations of the changes of the blood-medicine concentration of several kinds of main components in the plasma of a rat are detected at the same time. The methodological survey results indicate that the established method conforms to determination requirements on biological samples in a body; the method is good in sensitivity, high in specificity, stable, reliable, and suitable for detecting substances with lower contents.