582results about How to "Prevent coagulation" patented technology

A device for treating blood by extracorporeal circulation comprising a filter having a first chamber and a second chamber separated by a semi-permeable membrane. The device has an arterial line connected to the first chamber of the filter, a venous line issuing from the first chamber of the filter, a channel used for pre-infusion of a substance for regional anticoagulation and linked to the arterial line, a purge channel issuing from the second chamber of the filter, and an air separator on the venous line. The device also includes a line for post-infusion of a solution at least partially re-establishing the ionic equilibrium of the blood downstream of the air separator, the post-infusion line being configured immediately upstream of an air detector.

A microwave applicator for insertion into living body tissue for use in microwave coagulation and ablation treatments includes a microwave transmission line extending between an attachment end of the applicator and an antenna toward an insertion end of the applicator with an outer conductive sleeve forming an enclosed cooling fluid space around the transmission line. Circulation of cooling fluid is guided in the cooling fluid space by a guide sleeve. A fluid circulation system provides a plurality of fluid supply connectors and fluid return connectors which can be connected and used with any number of applicators between one and the number of the fluid supply connectors provided by the system. A portion of the applicator inserted into the tissue can stick to the tissue to stabilize the applicator during treatment. A warning marking on the applicator can be used during track ablation to prevent ablation of the patient skin tissue.

This invention relates to preparation and use of nanocomposites formed in situ within an elastomer host wherein the nanocomposite is comprised of an elastomer matrix and a dispersion therein of at least partially exfoliated clay platelets. Rubber composites can be prepared by blending such nanocomposite with additional elastomer(s), additional reinforcing filler(s) and / or a coupling agent. The invention further relates to the preparation of articles of manufacture, including tires, having at least one component comprised of said nanocomposite or said rubber composite. Such a tire component may be selected from, for example, tire tread and tire innerliner.

A method and apparatus to endovascularly treat blood vessels using a light beam that causes minimal collateral damage to surrounding tissue is described. The technique can improve the appearance of a blood vessel and / or reduce its size, as well as relieve other medical symptoms. The wavelength of the light beam can be selected so as to heat one or more chromophores either inside the blood vessel or within the blood vessel wall itself. Access to the vein lumen of the targeted blood vessel can be obtained via an optical fiber inserted into the blood vessel through a catheter.

A biodegradable antithrombotic conjugate having heparin and other anti-thrombotic moieties are introduced as side chains to the polymer backbone modified by click chemistry. Various bioabsorbable monomers and dimers such as valerolactone may be used in the monomer derivation, homo- and co-polymerization, and the conjugation with a biologically active molecule by click chemistry. A coating comprising a biocompatible and bioabsorbable polymer anti-thrombotic conjugate is applied to at least a portion of an implantable device to prevent or reduce the formation of thrombosis on the surface of the implantable device. A first or sub-layer of the coating is prepared by mixing a polymeric material and a biologically active agent with a solvent, thereby forming a homogeneous solution. A second or outer layer comprising the present anti-thrombotic conjugate may be applied over the inner drug-containing layers using, for example, a dip coating or spray coating process.

Disclosed is a stent assembly for expanding in vivo vessels, the assembly comprising first and second radially expandable mesh stents, wherein the first stent is separated by a predetermined distance from the second stent and a stent jacket spans the predetermined distance such that a first end of the jacket is operatively associated with the first stent and a second end of the jacket is operatively associated with the second stent.

Various embodiments include a method of producing chemically pure and stably dispersed metal and metal-alloy nanoparticle colloids with ultrafast pulsed laser ablation. A method comprises irradiating a metal or metal alloy target submerged in a liquid with ultrashort laser pulses at a high repetition rate, cooling a portion of the liquid that includes an irradiated region, and collecting nanoparticles produced with the laser irradiation and liquid cooling. The method may be implemented with a high repetition rate ultrafast pulsed laser source, an optical system for focusing and moving the pulsed laser beams, a metal or metal alloy target submerged in a liquid, and a liquid circulating system to cool the laser focal volume and collect the nanoparticle products. By controlling various laser parameters, and with optional liquid flow movement, the method provides stable colloids of dispersed metal and metal-alloy nanoparticles. In various embodiments additional stabilizing chemical agents are not required.

Catheter systems and methods are disclosed. An exemplary catheter includes an outer tubing housing and an inner fluid delivery tubing, the inner fluid delivery tubing having at least one fluid delivery port. The catheter also includes a deployment member movable axially within the inner fluid delivery tubing. A plurality of splines are each connected at a proximal end to the outer tubing and at a distal end to deployment member. A seal is provided between the outer tubing and the inner fluid delivery tubing. A gasket is provided between the deployment member and the inner fluid delivery tubing. Both the seal and the gasket are configured to prevent blood or other fluid from ingressing into the outer tubing.

Provided is a blood processing system having a stationary component separation chamber. Individual blood components as well as other particles and contaminates are separated from blood flowing through the separation chamber by optical traps configured to manipulate specific components are projected into the flow field of the chamber. Cells or particles of the selected components that are manipulated by the optical traps then may be directed from the flow field to individual reservoirs to collect quantities of the selected components.

A plastic container for liquid medicine, which, concerning the effective components of liquid medicine, is capable of prevention of deterioration in quality due to mixing of oxygen and water vapor, prevention of variation in concentration due to water volatilization and moisture absorption, etc. A plastic container for liquid medicine, which is a plastic container internally coated with DLC (diamond-like carbon) film wherein water vapor permeability is 0-0.006 g / container / day and oxygen permeability is 0-0.011 ml / container / day, such properties being obtained by optimizing the three conditions, composition, density and film thickness of the DLC film.

The present invention provides a hot melt conductor paste composition that includes conductive particles and glass particles dispersed in a thermoplastic polymer system. The hot melt conductor paste composition according to the invention is a solid at room temperature, but melts at a temperature of from about 35.degree. C. to about 90.degree. C. to form a flowable liquid that can be applied to a silicon substrate by screen printing. The hot melt conductor paste composition is particularly suitable for use in the fabrication of photovoltaic cells.

The invention provides a method that fully utilizes the characteristics of relatively high humidity content of flue gas in the existing wet desulfurization technology and employs vapor phase change theory to effectively remove SO2 through WFGD so as to cause PM2.5 to be condensed and enlarged as well as be removed effectively and a device thereof. The invention has simple technique, and arranging a moisture regulation chamber for the flue gas and a phase change condensing chamber in the existing flue gas wet desulfurization devices can cause the wet desulfurization device to have the effect of enlarging and removing PM2.5 granules. The invention is widely used in the existing wet desulfurization devices for the flue gas generated by power plants.

A ureal water tank (28), a storage of an aqueous urea solution, is located within a utility room (6G) in a right front section of a revolving frame (6), which is readily accessible from outside. In this instance, among a plurality of operating oil conduits (18), a working mechanism operating conduit (21) which supplies operating oil to a boom cylinder (5D) of a working mechanism (5) is arranged to run along exterior surfaces of the ureal water tank (28). Therefore, even if the ureal water tank (28) is located in a place with no heat source, the aqueous urea solution in the ureal water tank (28) can be stably kept in a heated state by utilization of heat of operating oil in circulation through the working mechanism operating conduit (21).

The present invention relates to compounds to inhibit blood coagulation, and more particularly to novel diketopiperazine derivatives, pharmaceutically acceptable salts and compositions thereof, to specifically inhibit thrombin. The compound has the following general structure wherein R1, R2 and R4 consist of a hydrogen, alkyl or aryl moiety, R3 consist of an alkyl or aryl moiety, wherein R5 consists of a hydrogen, alkyl, aryl, hydroaryl, heteroaryl, hydroheteroaryl, sulfonylalkyl, sulfonylaryl, sulfonylhydroaryl, sulfonylheteroaryl or sulfonylhydroheteroaryl moiety, and wherein R6 consists of a hydrogen, alkyl, aryl, hydroaryl, heteroaryl or hydroheteroaryl moiety. Also disclosed are methods of using the compound for treating coagulation disorders such as thrombosis and heparin associated thrombocytopenia.

A lubricant composition is disclosed that comprises: (a) a lubricant and (b) at least one molybdenum-containing compound in the form of surface-capped nanosized particles of the general formula: (Z)n(X—R)m wherein Z is an inorganic moiety comprising molybdenum and sulfur in the form of particles having dimensions in the range of from about 1 to about 100 nm; (X—R) is a surface-capping reagent wherein R is a C4 to C20 straight or branched-chain alkyl or alkylated cycloalkyl radical or radicals and X is a functional group capable of specific sorption and / or chemical interaction with molybdenum / sulfur moiety; n is the number of molecules of Z in the particles; m is an integer representing the amount of surface-capping reagents relative to a single particle; and the ratio of m to n is in the range of from about 1:1 to about 10:1.

The present invention provides a hot melt conductor paste composition that includes conductive particles and glass particles dispersed in a thermoplastic polymer system. The hot melt conductor paste composition according to the invention is a solid at room temperature, but melts at a temperature of from about 35° C. to about 90° C. to form a flowable liquid that can be applied to a silicon substrate by screen printing. The hot melt conductor paste composition is particularly suitable for use in the fabrication of photovoltaic cells.

A device for separating plasma from whole blood is provided having an evacuated primary collection chamber capable of fluid communication through a porous filter to an evacuated secondary collection chamber. An agglutinating agent is provided within the primary collection chamber so as to aggregate blood cells within a whole blood sample. The porous filter has a pore size which is small enough to capture the aggregated blood cells therein, yet large enough to permit plasma to transfer therethrough under pressures associated with conventional evacuated blood collection tubes. The primary and secondary collection chambers may be provided in separate containers or tubes, with transfer occurring therebetween through a transfer device including the porous filter therein.

A single-use system for separating blood and producing platelet concentrates includes an elongated container for receiving blood from a patient. The container has a movable plunger mounted within the blood container for expressing blood fractions separated during centrifugation of the container through a first port mounted at one end of said container, a second port mounted on the plunger, and a third port mounted on a plunger rod attached to the plunger.

A lubricant composition is disclosed that comprises: (a) a lubricant and (b) at least one molybdenum-containing compound in the form of surface-capped nanosized particles of the general formula: (Z)n(X—R)m wherein Z is an inorganic moiety comprising molybdenum and sulfur in the form of particles having dimensions in the range of from about 1 to about 100 nm; (X—R) is a surface-capping reagent wherein R is a C4 to C20 straight or branched-chain alkyl or alkylated cycloalkyl radical or radicals and X is a functional group capable of specific sorption and / or chemical interaction with molybdenum / sulfur moiety; n is the number of molecules of Z in the particles; m is an integer representing the amount of surface-capping reagents relative to a single particle; and the ratio of m to n is in the range of from about 1:1 to about 10:1.

A microwave applicator for insertion into living body tissue for use in microwave coagulation and ablation treatments includes a microwave transmission line extending between an attachment end of the applicator and an antenna toward an insertion end of the applicator with an outer conductive sleeve forming an enclosed fluid space around the transmission line. A fluid circulation system circulates fluid in the fluid space. A portion of or all of the circulating fluid can be injected into tissue that surrounds the applicator body from approximately the proximal end of a desired heating zone produced by microwave energy radiated from the antenna along the applicator body toward the proximal end of the applicator to hydrate and wet the tissue outside the proximal end of the desired heating zone to reduce the drying of this tissue and limit extension of the heating and ablation zone proximally along the applicator body.

This disclosure relates to materials fabricated from collagen and uses relates thereto. Typically, layers of collagen are stretched during a curing period and optionally coated or impregnated with an elastin like protein. In certain embodiments, these materials can be used in tissue repair or arranged into cylinders and utilized as a prosthetic vascular graft.

The invention belongs to the technical field of functional polymer materials, and in particular relates to a super-hydrophobic / super-oleophylic polyurethane oil-absorption sponge and a preparation method thereof. According to the technical scheme, the super-hydrophobic / super-oleophylic polyurethane oil-absorption sponge is prepared from the following components in parts by weight: 10-50 parts of polyisocyanates, 20-60 parts of a chain extender, 0.05-1.5 parts of a catalyst, 1-4 parts of a chemical foaming agent, 1.0-8.0 parts of a physical foaming agent, 0.5-3 parts of a cross-linking agent and 2-20 parts of other additives. The invention further provides the preparation method of the super-hydrophobic / super-oleophylic polyurethane oil-absorption sponge. The oil-absorption sponge provided by the invention has the advantages of super-hydrophobicity, super-oleophylicity, large specific surface area, porous polymolecular layers, capillary agglutination super oil-absorption property, environment inertia and the like, and is a high-efficiency rapid separation material which can be applied to emergency treatment on ocean oil overflowing pollution accidents.

The invention relates to a stable nanometer silver colloidal sol and a preparation method thereof. The stable nanometer silver colloidal sol adopts a silver containing compound, a protective agent and a solvent, water is used as the solvent, and the silver containing compound, the protective agent and the water are mixed so as to prepare the colloidal sol; and the particle diameters of nanometer silver grains are 1nm-10nm, and the nanometer silver grains are uniformly distributed in the colloidal sol, and can be preserved for 6 months to 24 months without changing at room temperature. The preparation method provided by the invention comprises the following steps of: adopting the silver containing compound and the protective agent as raw materials, adopting the water as the solvent, mixing the silver containing compound, the protective agent and the water so as to form a mixed solution which contains 200-10000ppm of silver, 0.02%-1% of protective agent, and the balance of water according to weight percent; and dissolving and mixing the components when the stable nanometer silver colloidal sol is prepared, then uniformly stirring, conducting ultrasonic processing, using a light source containing ultraviolet rays to light 30 minutes to 24 hours to obtain the nanometer silver colloidal sol containing the nanometer silver grains. The stable nanometer silver colloidal sol and the preparation method thereof provided by the invention have the advantages that the cost is low, the process is simple, and the stable nanometer silver colloidal sol is suitable for large-scale preparation.

A circuit for collecting a blood component includes a blood collection device provided with a blood collection needle through which blood is collected from a blood donor, a blood separator in which the blood collected by the above blood collection device is separated, a blood component collection bag in which a predetermined blood component separated by the above blood separator is collected, a blood line in which the blood collection needle is connected to an inlet of the blood separator, a line for removing an initial blood flow, which branches from a first branching portion formed in the blood line, and in which an initial flow of blood collected from the blood donor is removed, and an anticoagulant-injection line that branches from a second branching portion, formed in the line for removing the initial blood flow, and into which an anticoagulant is injected.

The present invention relates to a preparation method of a high-performance film-forming water-based drilling fluid system, which is characterized in that brine is used for confecting THE typical prescription of the high-performance film-forming water-based drilling fluid system, which is 10 percent of saturant NaCl solution, 1 percent to 3 percent of fluid loss additive, 0.3 percent to 0.5 percent of polymer viscosity increaser, 0.5 percent to 1 percent of coating agent, 2.5 percent to 5 percent of amine shale inhibitor, 3 percent to 4 percent of lubricant and 7 percent to 8 percent of film-forming agent. The drilling fluid system has the good performances of good film-forming character and strong inhibiting capability and is a novel drilling fluid system which can satisfy the requirement of the environmental protection and can replace oil-based drilling fluid (OBM).

A composition and method for formulating and delivering an adjuvanted immunological active agent, especially a vaccine, wherein adjuvant coagulation and concomitant loss of vaccine efficacy enhancement is mitigated or avoided. The adjuvanted, immunologically-active agent can be subjected to freezing, drying, freeze-drying, or lyophilization, and when reconstituted, retains a high level of potency. The present invention further provides for a composition and method for formulating and delivering a stable, adjuvanted, immunologically-active agent capable of being deposited on a transdermal delivery device or microprojection or array thereof.

The invention discloses a starch adhesive with nanometer oxidized cellulose size as the matrix. The starch adhesive is prepared from, by weight, 100 parts of nanometer oxidized cellulose size with the oxidation rate of 5-30%, 10-40 parts of starch, 2-5 parts of oxidizing agent, 0.1-2 parts of stabilizer, 0.1-2 parts of preservative and 0.1-2 parts of emulsified paraffin. The preparation method includes the steps of preparing nanometer oxidized cellulose size the with oxidation rate of 5-30%, adding starch and 2-5 parts of oxidizing agent to the prepared nanometer oxidized cellulose size in batches, adding stabilizer, preservative and emulsified paraffin after sufficient stirring, and sufficiently stirring the components at a temperature of 50-70 DEG C till all the components are evenly dispersed to obtain the starch adhesive. The starch adhesive is high in bonding strength and high in water resistance. By means of the preparation method, the solvent replacement and drying process is avoided, energy consumption is greatly lowered, and labor intensity is reduced.

The invention discloses a preparation method of high-quality and large-scale novel two-dimensional material, namely, single-crystal less-layer antimonene. The liquid phase ultrasonic stripping technology is adopted, and a fifth main-group antimony nano-sheet is stripped through ultrasonic assisting of antimony powder, ethanol and surfactant. Firstly, the antimony powder and ethanol are mixed at room temperature; secondly, a proper amount of surfactant is added, the mixture is ultrasonically treated for a period of time under certain power, and then antimonene is massively prepared. Preparation process parameters are adjusted, and the size of antimonene can be adjusted. Reaction conditions are mild, the preparation process is simple, and the preparation method can be used for large-scale preparation. The less-layer antimonene prepared through the method is uniform in thickness and size, adjustable in size, high in purity and good in degree of crystallinity.