The invention discloses a pharmaceutical composition for treating oral ulcer and a preparation method thereof. The pharmaceutical composition contains the ingredients, namely
panax quinquefolium,
houttuynia cordata thunb,
cassia seeds and honey. A preparation method of the pharmaceutical composition comprises the steps: (a)
grinding panax quinquefolium of a certain ratio, sieving, adding
ethanol to extract, filtrating, recovering the
ethanol, and concentrating so as to obtain an extract 1 for later use; (b)
grinding the
cassia seeds of a certain ratio, and sieving so as to obtain a material 2 for later use; (c) mixing the
houttuynia cordata thunb of a certain ratio with the material 2, adding
purified water to soak, decocting, filtrating, and concentrating so as to obtain an extract 3 for later use; (d) mixing the honey of a certain ratio with
purified water and
mannitol according to a certain ratio, and carrying out
freeze drying so as to obtain freeze-dried
powder 4 for later use; (e) uniformly mixing the extract 1 and the extract 3,
drying, crushing, and sieving so as to obtain dried
powder 5 for later use; and (f) uniformly mixing the freeze-dried
powder 4 and the dried powder 5 so as to obtain dried powder 6, wherein the dried powder 6 is prepared into a pharmaceutically-acceptable
dosage form.