Novel preparing technique of

A preparation technology and preparation technology, which is applied in the field of Chinese patent medicine production technology, can solve the problems of loss and small dosage, and achieve the effect of convenient taking and carrying, small dosage, and guarantee of medication needs

Inactive Publication Date: 2005-01-26
毛友昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But making a general survey of the technology and preparations of the above-mentioned products all have weak points: (1) Guipi Pills (included in the Pharmacopoeia of the People's Republic of China 2000 edition one) its technology is: in the prescription, eleven medicinal materials are pulverized into fine powder, added Appropriate amount of refining honey / honey water to make large and small honey pills / water honey pills
The dosage form of Astragalus etc. adopts water extraction and alcohol precipitation process, and Atractylodes macrocephala, Poria cocos and jujube seed adopts alcohol extraction process. While solving the problem of liquid preparation clarification, it also causes the loss of water-soluble active ingredients such as polysaccharides, etc.
[0003] To sum up, although there are quite a few Guipi preparations, there is none that can not only fully retain the active ingredients of the prescribed Chinese medicinal materials to ensure the curative effect, but also achieve exquisite preparation and small dosage, which fully embodies the modernization of traditional Chinese medicine preparations.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1: Preparation of Guipi Capsules

[0041]Clean the ten herbs separately, remove impurities, and pass the test for later use; crush the ten herbs in the prescription into coarse powder for later use; take angelica, tangerine peel, ginger, Bupleurum, Codonopsis, and Atractylodes macrocephala, add water to distill, extract volatile oil, and use appropriate amount of non-toxic Dissolve in water and ethanol for later use; ultrafilter the distilled aqueous solution for later use; use 90% ethanol to heat and reflux the medicinal residues, Radix Astragali, Cimicifuga, and Jujube for 2 times; The first time, 2 hours each for the second time, and 1 hour for the third time, add the dregs of the above-mentioned astragalus and other ethanol extractions to the second decoction, combine the decoction, ultrafiltration, and the filtrate and the above-mentioned angelica after recovering ethanol The ethanol extract, angelica and other aqueous solutions are combined, vacuum film...

Embodiment 2

[0042] Example 2: Preparation of Guipi Capsules

[0043] Clean the ten herbs separately, remove impurities, and pass the test for later use; crush the ten herbs in the prescription into coarse powder for later use; take angelica, tangerine peel, ginger, Bupleurum, Codonopsis, and Baizhu, add water to distill, extract volatile oil, and make- Cyclodextrin inclusion compound for later use; distilled aqueous solution for further use by ultrafiltration; medicine dregs, astragalus, cohosh, and jujube were heated and refluxed twice with 90% ethanol, and the extracts were combined, ultrafiltered, and ethanol was recovered from the filtrate for later use; licorice was added with water Decoct 3 times, 2 hours each for the first and second time, and 1 hour for the third time. Add the dregs of the above-mentioned astragalus and other alcohol-extracted herbs to the same decoction in the second decoction, combine the decoction, ultrafiltration, and the filtrate and the above-mentioned angeli...

Embodiment 3

[0044] Embodiment 3: the preparation of Guipi tablet

[0045] Clean the ten herbs separately, remove impurities, and pass the test for later use; crush the ten herbs in the prescription into coarse powder for later use; take angelica, tangerine peel, ginger, Bupleurum, Codonopsis, and Atractylodes macrocephala, add water to distill, extract volatile oil, and use appropriate amount of non-toxic Dissolve in water and ethanol for later use; ultrafilter the distilled aqueous solution for later use; use 90% ethanol to heat and reflux the medicinal residues, Radix Astragali, Cimicifuga, and Jujube for 2 times; The first time, 2 hours each for the second time, and 1 hour for the third time, add the dregs of the above-mentioned astragalus and other ethanol extractions to the second decoction, combine the decoction, ultrafiltration, and the filtrate and the above-mentioned angelica after recovering ethanol Combine the ethanol extract and angelica and other aqueous solutions, concentrat...

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PUM

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Abstract

The invention provides a novel preparing technique of 'Gui Pi' and its formulation characterized in that characterized by the modification to the preparing process by using the novel medicament preparing technologies, which achieves the beneficial effects of good curative effect, small amount of administration and easiness in carrying.

Description

technical field [0001] The invention relates to the technical field of preparation technology of Chinese patent medicines, in particular to the preparation technology and preparation of Guipixin Background technique [0002] Guipi Decoction comes out of "Jisheng Fang", which consists of Codonopsis, Atractylodes macrocephala (stir-fried), Astragalus (honey-roasted), licorice (honey-roasted), Poria cocos, polygala (made), jujube seed (stir-fried), longan meat, angelica, wood Composed of eleven flavors of incense and jujube (pitted), it is a famous prescription for invigorating the spleen and nourishing the heart in traditional Chinese medicine. It has the functions of nourishing qi and strengthening the spleen, nourishing blood and calming the nerves. Dizziness, limb fatigue, loss of appetite, metrorrhagia, hematochezia and other symptoms, the curative effect is remarkable. With the development of research on traditional Chinese medicine preparations, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K9/16A61K9/20A61K9/48A61P1/14A61P25/20
Inventor 毛友昌毛小敏
Owner 毛友昌
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