1241 results about "Oral ulcers" patented technology

The invention provides the application of the effective fraction of a periplaneta Americana in preparing drugs for inhibiting herpesvirus (HSV) infection and preventing and treating oral ulcer and/or genital herpes. The effective fraction of the periplaneta americana is obtained by extracting fresh or dry periplaneta Americana belonging to the blattidae family with ethanol aqueous solution, purifying with macroporous adsorption resin column, and refining by eluting with ethanol solution. The effective fraction of the periplaneta Americana has distinct HSV inhibitory activity, and can be processed into medicinal preparations or health products for inhibiting HSV infection and preventing and treating related diseases or symptoms.

The invention relates to a toothpaste containing coenzyme Q10 and a preparation method thereof, in particular to a composition of toothpastes, belonging to the field of oral healthcare products; based on weight percentage, the coenzyme Q10 in the toothpaste is 1-2% and Chinese herbal extract is 0.5-2%; the rest of accessories are conventional materials for preparing toothpastes. The formulation proportion of the components in the toothpaste is preferably as follows: 2% of coenzyme Q10 mixture, 0.7% of Chinese herbal extract, 35% of abradant, 1.5% of bonding agent, 35% of wetting agent, 0.2% of flavoring agent, 2.5% of foaming agent, 1.5% of essence and 21.6% of deionized water. The toothpaste containing coenzyme Q10 has the healthcare functions the same as the common toothpastes, such as brightening and cleaning the teeth, stopping bleeding of gums and healing oral ulcer; besides, the coenzyme Q10 and Chinese herbal extract permeate the gum cell membrane so that the gum cell obtains energy and tissue vigor is strengthened, thereby essentially conserving the gums, preventing periodontitis, gingivitis and gingival atrophy to reach the aim of strengthening the gums and fixing teeth.

The invention discloses an oral composition containing Ectoine and hyaluronic acid and application of the oral composition. The oral composition is prepared from, by mass, 0.1-5% of high molecular weight hyaluronic acid or salt thereof, 0.1-5% of low molecular weight hyaluronic acid or salt thereof, 0.01-1% of tea polyphenol, 1-3% of xylitol, 0.1-1% of Ectoine and the balance water, and the totalpercentage is 100%. Accordingly, the Ectoine, different molecular weights of hyaluronic acid or salt thereof, tea polyphenol and xylitol are compounded, the bio-safety is high, the synergetic effect is achieved, the effects of nursing wound surfaces, diminishing inflammation, promoting healing and the like are achieved, and the oral composition is applicable to oral care application such as oral care after cancer chemotherapy and oral ulcer care and can also be applied to the field of medical products, medical equipment and disinfection products.

The present invention provides a honeysuckle health care tea, which is prepared from the following raw materials, by weight: 2-4 parts of honeysuckle, 1-3 part of chrysanthemum, 1-3 parts of peppermint, 4-6 parts of medlar, 2-4 parts of rose, 4-6 parts of obtuseleaf senna seed, 2-4 parts of cape jasmine, and 6-8 parts of lotus seed. The preparation process comprises: selecting raw materials according to the weight part ratio, washing, completely drying, crushing to prepare into coarse powder, mixing, carrying out sterilization, packaging and closing the bag. According to the present invention, the honeysuckle health care tea has effects of heat clearing, pathogenic fire removing, blood pressure lowering, blood fat reduction, and preventions and treatments of oral ulcer, breath odor, acne and constipation, can provide effects of mind stabilizing, health enhancing, body building, immunity increase after constantly drinking, and can further provide effects of blood circulation activating, menstruation regulating, spot removing and beautifying after being taken by women; the process is simple, and the produced health care tea has characteristics of pure tea soup, slight and elegant fragrance, and pure flavor, and is suitable for health preserving and health care; and the processes of microwave sterilization and vacuum packaging are adopted so as to prolong a product freshness keeping period, and provide safety during taking.

The invention discloses oral ulcer powder, which comprises the following raw material medicaments: 8 to 12 grams of natural indigo, 8 to 12 grams of borax (calcined), 16 to 24 grams of persimmon frost, 8 to 12 grams of ivory flake (roasted), 3 to 6 grams of pearl, 8 to 12 grams of refined mirabilite powder, 2.4 to 3.2 grams of human fingernail (roasted), 3 to 5 grams of dragon's blood, 8 to 10 grams of cutch, 1.6 to 2.4 grams of puffball, 2.4 to 4.2 grams of exposed honeycomb (sauted), 3 to 5 grams of calcined alum, 8 to 13 grams of watermelon frost, 0.4 to 0.9 gram of asarum, 0.3 to 0.8 gram of menthol, 1.6 to 2.4 grams of snake slough (roasted), 3 to 9 grams of elephant's hide, 6 to 10 grams of liquorice root, 0.6 to 1 gram of bezoar, 0.6 to 1 gram of steviosin and 0.15 to 0.3 gram of borneol. A preparation method comprises the following steps of: grinding the medicinal materials into fine powder capable of passing through a screen of 250 meshes, and preparing the oral ulcer powder in a ratio. The oral ulcer powder has the advantages of no bitter taste, no toxic or side effect and good treatment effect.

The invention discloses a compound growth factor collagen sustained-release carrier material for promoting repair of various traumas in oral and maxillofacial regions and a method for preparing the same. In order to overcome the defect of poor curative effect existing in the conventional medicaments for treating the traumas of various tissues such as an oral cavity and a face, a bioactive collagen sustained-release material is prepared by combining collagen modified by liposome, chitosan, glycosaminoglycan and the like with one or more of a basic fibroblast growth factor (bFGF), a platelet derived growth factor (PDGF-BB), a vascular endothelial growth factor (VEGF) and a keratinocyte growth factor (KGF). The bioactive collagen sustained-release material is characterized in that: each gram of bioactive collagen sustained-release material contains not less than 10ng of growth factors, and the bioactive collagen sustained-release material has the obvious effect of treating various facial tissue traumas such as tooth extraction wound, oral ulcer, facial nerve injury, mandibular defect and the like. The collagen sustained-release carrier material can continuously release an effective amount of the growth factors to the wound for a long time, fully exert the inducing effect of the growth factors and obviously shorten the time for wound healing so as to fulfill the aim of treatment.

The invention discloses a toothpaste containing an American cockroach extract and a preparation method thereof. According to the invention, the American cockroach extract prepared under specific process conditions is added into the toothpaste as an active constituent having an effect of adjuvant therapy, and special biological activity, such as alanine, in American cockroach is utmostly retained in the extract, so the toothpaste not only has the effect of synchronous nursing of the oral cavity, teeth and gums, but also has remarkable therapeutic effects on oral ulcer; therefore, the toothpaste has an immense application value.

The invention discloses an application of a centella extract in Chinese medicinal toothpaste and relates to the technical field of toothpaste, namely in a preparation technique of the toothpaste, the centella extract is added into the toothpaste as an ancillary drug raw material for resisting inflammation and dental ulcer. In preparation of the toothpaste provided by the invention, centella is added as a raw material of a natural plant active component, and the centella not only is safe to use and has remarkable effects for resisting inflammation and dental ulcer, but also can prevent periodontitis, gingivitis and dental ulcer and restore oral mucosa, moreover, the toothpaste adopts single drug, so the production technique is simple, the source of the traditional Chinese medicine raw materials is wider, and the cost is lower.

The invention discloses a compound toothpaste with functions of antisepsis, anti-inflammation, acid prevention and desensitization, and a preparation method of the compound toothpaste. The invention adopts natural propolis and traditional Chinese medicine with functions of analgesia, anesthesia and antiallergic effect as main effective preparations, is compounded with the traditional western medicine and is supplemented by biotechnology, so that the compound toothpaste with the functions of antisepsis, anti-inflammation, acid prevention and desensitization can be prepared. The compound toothpaste can be used for preventing and treating periodontitis, dental ulcer, enamel trauma, toothache and sensitivity of teeth, and is also capable of enhancing the self repairing capability of oral cavity tissue, enabling the gum to be healthy, improving the microcirculation, guaranteeing the oral cavity to be healthy and improving the comprehensive antiallergic capability of teeth.

The invention discloses a preparation method of hyaluronic acid nanogel. The target product hyaluronic acid nanogel is synthesized from chitosan quaternary ammonium salt and sodium hyaluronate through an ion crosslinking and polymer coacervation two-step technology, the average particle size of the product is 150-230nm, and the Zeta potential of the product is -28.6 ~ -36.7mV. The hyaluronic acid nanogel prepared in the invention can be used for treating oral ulcer, can maintain the effective active concentration of a basic fibroblast growth factor in the oral ulcer position for a long time, and improves the clinic treatment effect.

The invention relates to an asarum heterotropoide extract of asarum as well as a preparation method and application of the extract, and particularly relates to an asarum heterotropoides extract of asarum. The extract comprises essential oil and a water extract, wherein the essential oil accounts for 2% by weight, and the water extract accounts for 98% by weight. The preparation method of the extract comprises the following steps: extracting essential oil in asarum heterotropoides roots and rhizomes by adopting a supercritical fluid extraction method; including the essential oil by cyclodextrin, and hermetically storing for later use; condensing, refluxing and extracting dregs by water; filtering by an aqueous extract, and drying to obtain powder; finally evenly mixing a beta-cyclodextrin inclusion compound with dry powder, so as to obtain the asarum heterotropoides extract, and hermetically storing. Application of the asarum heterotropoides extract in preparation of two oral appliances relates to a drug paste and an oral patch. The drug paste disclosed by the invention has the effects of preventing and treating odontalgia, gingivitis, periodontitis and dental ulcer. The oral patch has the efficacies of treating the dental ulcer, easing pain, diminishing inflammation and preventing gum bleeding.

The invention discloses a medicine for treating children stomatocace and a method for preparing the same. The medicine is mainly prepared by the following components of the yellow-corktree bark, the dried rehmannia root, the figwort root, the honeysuckle, the fiveleaf akebia, the Chinese goldthread and the root-bark of tree peony according to a certain proportioning by weight. The medicine of the invention has the functions of resolving heat, removing toxins, diminishing inflammation, killing bacteria, cooling blood and promoting wound healing and is mainly used to treat the children stomatocace with fast effect and high cure rate.

The invention discloses a sublingual cigarette and a preparation method of the sublingual cigarette and belongs to the field of novel tobacco products. The sublingual cigarette comprises, by mass, 0.01%-6% of nicotine, 3%-15% of non-carbonhydrate sweet substances, 5%-35% of sodium alginate, 45%-80% of green bean starch, 3%-8% of calcium sulphate, 0.5%-3% of licorzince, 0.2%-0.8% of vitamin and 0%-0.6 of menthol (or peppermint oil). Compared with existing novel tobacco products, the sublingual cigarette has the advantages that rapid sublingual dissolution can be achieved, onset is fast and no residue exists; the sweetness of the sweet substances is high, the dosage is small, and the cost is saved; the physiological needs of a consumer can be met, and the functions of decayed tooth prevention and oral ulcer can be achieved; elevated blood glucose can not be caused, and the sublingual cigarette is applicable to long-term use of the diabetic population.

The invention discloses a deep-cleaning, antibacterial and tooth-protecting mouth wash based on chitosan derivatives. The mouth wash is prepared from, by weight, 3% of chitosan derivatives, 5% of glycerol, 1.5% of xylitol, 2% of efficient solubilizer, 0.55% of citric acid, 0.3% of sodium citrate, 0.25% of malic acid, 0.12% of menthol, 0.15% of mint fragrance, 2% of propolis extracts, 3.5% of tea leaf extracts, 0.07% of caramel colour, 0.04% of saccharin sodium, 0.2% of chlorhexidine, 0.0003% of domiphen bromide and the balance deionized water. The invention provides the deep-cleaning, antibacterial and tooth-protecting mouth wash based on the chitosan derivatives and the preparation method of the mouth wash. The mouth wash prepared through the method has the functions of inhibiting bacteria, removing dental plaque and preventing oral ulcer, gingivitis and other oral diseases, and is good in antibacterial effect, quick in effect, free of toxic and side effects and comfortable in mouthfeel.

The invention provides a traditional Chinese medicine preparation for treating oral inflammation and a preparation method thereof. The traditional Chinese medicine preparation mainly comprises the following raw materials in parts by weight: 1-100 parts of manyprickle acanthopanax root, 1-80 parts of lonicera confuse, 1-80 parts of raw glycyrrhiza, 1-60 parts of balsamiferou blumea herb, 1-100 parts of Chinese olive, 1-60 parts of vegetable sponge of luffa and 30-100 parts of European verbena. The preparation method comprises the following steps: water is added, the raw materials are extractedand filtered and the filtrate is taken; the filtrate is concentrated and precipitated with ethanol; supernate is taken and the ethanol is recovered until the smell of ethanol disappears; the filtrateis concentrated again; and corresponding excipient is added to obtain the traditional Chinese medicine preparation in various forms. The preparation takes natural traditional Chinese medicine as the raw materials, thereby having less toxic and side effects, treating both principal and secondary aspect of disease and thoroughly curing oral inflammation such as oral ulcer, oral smell, periodontitis, gingivitis and the like. In addition, the oral inflammation is not prone to relapse.

An oral sticking sheet of the recombinant human granulocyte-macrophage colony stimulating factor for treating oral ulcer is composed of a water-insoluble protecting layer and an adhesive layer containing said active medicine, adhesive, the stabilizer for stabilizing the activity of protein and percutaneous absorption promoter.

The invention relates to a purely Chinese traditional medical film for curing oral ulcer, which is characterized in that according to weight percentage, the purely Chinese traditional medical film consists of 0.03-0.05g of allicin, 2-4g of catechu, 1-2g of borneol, 0.5-1.5g of borax, 0.5-1.5g of corn mint, 1-3g of gum tragacanth, 30-40ml of sodium alginate, 4-5ml of sodium carboxymethylcellulose, ethanol and 100ml of distilled water. The purely Chinese traditional medical film is completely purely Chinese traditional medical formula, is the best formulation for curing ulcer of oral mucosa, avoids side effects caused by using antibiotics and glucocorticoid, and has the advantages of obvious curative effect, convenient use, small side effect and curing cause and symptom.

The invention discloses a traditional Chinese medicine for treating recurrent oral ulcer and a preparation method. The traditional Chinese medicine is prepared from the following components in parts by weight: 8-12 parts of figwort root, 2-5 parts of plaster stone, 10-15 parts of common lophatherum herb, 5-10 parts of burdock, 5-6 parts of root bark of the peony tree, 5-10 parts of liquoric root,5-8 parts of honeysuckle, 7-10 parts of root of rehmannia, 10-15 parts of asarum, 5-7 parts of tuckahoe, 4-7 parts of angelica root, 5-8 parts of fructus forsythiae, 5-10 parts of dandelion, 10-15 parts of corktree, 10-15 parts of balloon flower and 1-3 parts of borneol. The preparation method comprises the following steps of: adding water into the traditional Chinese medicine according to the weight of the components to decoct and extract; taking filtrate or supernatant; and bottling and storing for later use. The Chinese medicinal preparation has the effects of compatibility of various medicines, capability of complementing each other, combined action of clearing heat and cooling blood, clearing heat and removing toxicity, activating blood circulation to dissipate blood stasis, subsiding swelling and dissipating stagnation, and nourishing qi and alleviating pain. The traditional Chinese medicine has the advantages of high clinical curative effect, quick response, short treatment period, no obvious toxic or side effect and the like, and is an ideal medicine for treating the recurrent oral ulcer.

The invention relates to an open-throat sword spray used for treating throat diseases and a preparation method thereof, and relates to a drug which has the effects of clearing heat and removing toxicity and relieve swelling and pains, and is used for treating diseases such as acute laryngopharyngitis, chronic laryngopharyngitis, amygdalitis, swollen sore throat, stomatitis, dental ulcer, dry mouth and bitter mouth, swollen gums, recurrent oral ulcer and the like, and particularly relates to an oral preparation prepared by using four traditional Chinese medicinal materials containing ardisia crenata sims, radix sophorae tonkinensis, cicada slough and menthol as raw materials. Compared with a conventional method, the method has optimized extraction process parameters, increased transfer rate of active ingredients and increased yield. Besides, the method has more stable and reliable quality, better effect curative effects and better security.