Pharmaceutical composition for treating oral ulcer and preparation method thereof
A technology for oral ulcers and compositions, which is applied in the field of pharmaceutical compositions for treating oral ulcers, can solve problems such as being unfavorable to industrialization, cost control, complex components, and the like, and achieve a reliable preparation method, simple formulation, and easy-to-obtain medicinal material resources. Effect
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Embodiment 1
[0029] prescription:
[0030] components
Dosage(kg)
American ginseng
5
Houttuynia cordata
25
Cassia
18
Honey (30% water content)
25
Mannitol (powder)
16.5
[0031] a) Weigh 5kg of American ginseng, grind it into powder, pass through a 24-mesh sieve, add 2 times of 60% ethanol solution to extract for 1.5 hours, extract 2 times, mix the extract twice, filter to obtain the filtrate, recover ethanol under reduced pressure, and concentrate to The relative density was 1.1, and the extract 1 was obtained and set aside.
[0032] b) Weigh 18kg cassia seeds, pulverize them, and pass through a 24-mesh sieve to obtain material 2, which is set aside.
[0033] c) Weigh 25kg of Houttuynia cordata, mix with material 2, add 3 times of purified water, soak for 30 minutes, decoct for 2 hours, decoct for 3 times, combine the extracts, filter to obtain the filtrate, concentrate to a relative density of 1.15, The extract ...
Embodiment 2
[0038] prescription:
[0039] components
Dosage(kg)
American ginseng
20
Houttuynia cordata
7
Cassia
5
Honey (30% water content)
7
Mannitol
10
microcrystalline cellulose
12
[0040] a) Weigh 20kg of American ginseng, grind it into powder, pass through a 30-mesh sieve, add 2 times of 75% ethanol solution to extract for 3 hours, extract 2 times, mix the extract twice, filter to obtain the filtrate, recover ethanol under reduced pressure, and concentrate When the relative density is 1.2, extract 1 is obtained and set aside.
[0041] b) Weigh 5kg cassia seeds, crush them, and pass through a 50-mesh sieve to obtain material 2, which is set aside.
[0042] c) Weigh 7kg of Houttuynia cordata, mix with material 2, add 3 times of purified water, soak for 20 minutes, decoct for 2 hours, decoct for 3 times, combine the extracts, filter to obtain the filtrate, concentrate to a relative density of 1.25, ...
Embodiment 3
[0047] prescription:
[0048] components
Dosage
American ginseng
8
Houttuynia cordata
20
Cassia
15
Honey (30% water content)
10
Mannitol
15
[0049] a) Weigh 8kg of American ginseng, grind it into powder, pass through a 50-mesh sieve, add 2 times of 65% ethanol solution to extract for 2.5 hours, extract 2 times, mix the extract twice, filter to obtain the filtrate, recover ethanol under reduced pressure, and concentrate When the relative density is 1.4, extract 1 is obtained and set aside.
[0050] b) Weigh 15kg cassia seeds, crush them, and pass through a 30-mesh sieve to obtain material 2, which is set aside.
[0051] c) Weigh 20kg of Houttuynia cordata, mix with material 2, add 3 times of purified water, soak for 38 minutes, decoct for 2.8 hours, decoct for 3 times, combine the filtrate to filter, concentrate to a relative density of 1.21, and obtain extract 3, spare.
[0052] d) Weigh 10kg of ho...
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