80 results about "Aphthous ulcer" patented technology

An ultrasonic toothbrush having spatially extended functionality to treat various oral diseases in addition to removing plaque and treating gingivitis is disclosed. In addition to the ultrasonically activated bristles, the toothbrush incorporates a multi directional ultrasound transducer system, which spatially irradiates the oral cavity with ultrasonic pressure waves, operational to loosen plaque, to remove periodontal bacteria from teeth and gums, and to simultaneously treat and destroy disease causing bacteria and bacterial chains on the inside surfaces of cheeks and lips, providing relief from Recurring Aphthous Stomatitis, Lichen Planus, and Mucositis. Various configurations are disclosed, including user removable and replaceable brush heads and ultrasound treatment heads. A motorized version featuring sonic frequency orbital vibration brush head and bristle tufts is described.

The invention relates to a multifunctional drug shoe pad capable of simultaneously carrying out pharmacotherapy, magnetotherapy and phototherapy, belonging to the field of the external application of traditional Chinese medicine. The shoe pad comprises a surface layer, a drug carrying layer and a bottom layer. The shoe pad is characterized in that drugs carried in the drug carrying layer mainly comprise dozens of selected Chinese medicinal herbs such as angelica sinensis, herba epimedii, rhizoma curculiginis, angelica roots, cassia barks, radix sophorae flavescentis, ligusticum wallichii, borneol, camphor, menthol, azone, and the like as well as substances with good physiotherapy effects, such as natural magnetite powder, far infrared ceramic powder, and the like. The invention has the use effect of an ordinary shoe pad and also the disease adjuvant therapy effect which cannot be achieved by the ordinary shoe pad, has good adjuvant therapy effects on various diseases such as headache, dizziness, agrypnia, hypertension, chronic pharyngitis, aphthous stomatitis, canker sores, epistaxis, heel bony spurs, achilles tendonitis, spontaneous perspirat, night sweat, abnormal menstruation, dysmenorrhea, and the like and also has complete function and stronger practicability.

The invention discloses a traditional Chinese medicine for treating stomach fire toothache and aphthous stomatitis, which comprises Chinese gold thread, cimicifuga foetida, gypsum, bark of peony tree, root of rehmannia, and liquorice. The six medicinal herbs are decocted in 1,500ml of water until medicinal soup of 250ml is obtained. The traditional Chinese medicine is taken twice every day, and the diseases can be cured after the medicine is taken 3-5 times. The medicine has the efficacy of clearing heat and detoxicating, invigorating blood circulation and removing blood stasis, can achieve the purposes of curing the stomach fire toothache and the aphthous stomatitis, and has the advantages of good curative effect and quick response with the total effective rate reaching 98.2%.

Pharmaceutical compositions are provided which comprise effective amounts of antimicrobials, anti-inflammatories, and antihistamines, to provide an ulcer medication which prevents secondary infections and promotes healing while providing immediate relief from pain. The composition may be used to treat a variety of ulcers including but not limited to intraoral aphthous ulcers and non-oral lesions. The compositions of the present invention may also be combined with materials capable of forming seals over ulcers or lesions to further promote the healing process.

The invention relates to a medicine for treatment of swollen and sore throat and aphthous stomatitis, especially to a traditional Chinese medicine composition for treatment of swollen and sore throat and mouth. The medicine combination mainly comprises following ingredients, by weight: 4 to 12 portions of Chinese angelica, 5 to 11 portions of radix scrophulariae, 7 to 15 portions of raw rehmannia root, 4 to 10 portions of honeysuckle flower, 13 to 18 portions of dandelion, 4 to 11 portions of pinellia, 2 to 6 portions of pericarpium citri reticulatae, 5 to 12 portions of polyporus, 4 to 12 portions of poria cocos, 12 to 17 portions of gypsum, 3 to 7 portions of licorice, 4 to 9 portions of sophora flavescens and 11 to 18 portions of caulis piperis kadsurae. The traditional Chinese medicine combination for treatment of swollen and sore throat and aphthous stomatitis is capable of nourishing yin and promoting the secretion of the body fluid, nourishing blood, moistening dryness and lubricating intestines, clearing away heat and drying dampness, dispelling wind and heat, removing and cleaning blood poison, reducing excess and relieving inflammation, and treating the swollen and sore throat and mouth fundamentally, and possesses fewer toxic or side effects, and is effective in treatment.

Pharmaceutical compositions are provided which comprise effective amounts of antimicrobials, anti-inflammatories, and antihistamines, to provide an ulcer medication which prevents secondary infections and promotes healing while providing immediate relief from pain. The composition may be used to treat a variety of ulcers including but not limited to intraoral aphthous ulcers and non-oral lesions.

The present invention provides methods for treating or preventing periodontal disease in a mammal subject. The inventive methods comprise topically administering to the subject an effective amount of a H2 antagonist encapsulated in liposomes. Preferably, the H2 antagonist, for example, Cimetidine, is encapsulated into paucilamellar liposomes, such as Novasome® microvesicles. The inventive methods may be used to treat and / or prevent gingivitis, periodontitis, aphthous ulcers, or herpetic stomatitis. Alternatively, the inventive methods may be used to treat and / or prevent a systemic disease associated with periodontal disease, such as cardiovascular diseases, pregnancy complications, and diabetes.

The invention discloses a biological type drug membrane and a preparation method thereof. The main components of the biological type drug membrane are leaven and additives including film-forming material, plasticizer, aromatic and so on. The making process flow of the drug membrane is as follows: firstly the slurry of the film-forming material is prepared; inactivated leaven and the additives are added and evenly mixed, and then the processes of deaeration, coating, drying, deciduation and packing are carried out. Compared with the prior art, by adopting the leaven as the main component, the drug membrane not only plays a role of protecting a wound surface but also improves the nutrient metabolism of oral mucosa, protects various cell injuries and enhances body immunity. In addition, the drug membrane has the characteristics of small volume and light weight and is also more convenient for being easy to be packed, stored, transported, carried over and used. The biotype-drug membrane is mainly used for treating various congestion, erosion and ulcerous lesion. And the biological type drug membrane has good effect on treating recurring Aphthous ulcer and oral lichen planus (congestive and erosive type).

The invention discloses a medicine for treating contagious ecthyma. Each milliliter of the medicine comprises: 0.025-0.028g of ribavirin, 0.0035-0.004g of ceftiofur sodium, glycerin with a volume concentration of 2%-2.5%, and the balance normal saline. The medicine of the invention can rapidly inhibit replication of a contagious ecthyma virus, and prevent an aphthous ulcer surface from developing into secondary bacterial infections. The medicine provided in the invention has the advantages of uneasy volatilization, sufficient sources of medicine components, low price, convenient use, good treatment effect, cure rate up to 75%, lamb mortality declined by 5%, condition improvement rate of 90%, and no harm to breeders.

Provided by the present invention are methods of treating a variety of disorders including AIDS, arthritis (rheumatoid arthritis, osteoarthritis, spondyloarthropathies), antibiotic induced diarrheal diseases (Closbidium difficile), multiple sclerosis, osteoporosis, gingivitis, peptic ulcer disease, esophagitis, diabetes, retinitis, uveitis, reperfusion injury after myocardial infarction (MI) or cerebral vascular accident (CVA), aphthous ulcers (oral), atherosclerosis (plaque rupture), prevention of tumor metastases, asthma, preeclampsia, acute pancreatitis, psoriasis, infertility and allergic disorders such as rhinitis, conjunctivitis, and urticaria.

A Chinese medicine in the form of picking for treating recurrent oral ulcer and aphthous stomatitis is prepared from pearl, artificial bezoar, natural indigo, borneol and talc through pulverizing, sieving, proportional mixing, adding carbomer and other additives, stirring, pressing and coating one surface.

The invention relates to a gargle for treating recurrent aphthous ulcer and periodontitis and a preparation method of the gargle. The preparation method of the gargle comprises the following steps: soaking honeysuckle, asiatic moonseed rhizome, glaucescent fissistigma roots, gynostemma pentaphyllum, conic gymnadenia rhizome and rose mallow roots, and performing water extraction and alcohol precipitation on the six ingredients, taking toad venom and soaking toad venom with alcohol, extracting, adding a certain proportional quantity of an anti-caries sweetening agent, an acid regulator, a preservative and an appropriate amount of water after taking menthol and adding an appropriate amount of ethanol for dissolving, uniformly mixing, sterilizing and filtering. The gargle has the advantages that the formula is reasonable, the ingredients are easy to obtain, the production technology is simple, the reproducibility is good, the curative effect is remarkable, toxic or side effects are small, recurrent aphthous ulcer and periodontitis (gingivitis and periodontitis) are treated, symptoms, such as oral ulcer, exudation, hyperaemia, hemorrhage, edema and pain, caused by recurrent aphthous ulcer and periodontitis, can be markedly eliminated, recurrent aphthous ulcer and periodontitis are difficult in recurring, the taste is good, and the gargle is suitable for people of all ages.

The invention discloses health care throat lozenge capable of clearing heat from throat and a preparation method thereof. The throat lozenge contains the following substances: soluble starch, lactose, mannitol, sucrose, platycodon extract, terminalia chebula extract, momordica grosvenori extract, scaphium scaphigerum extract, lonicera japonica extract, arctium lappa extract, vitamin B1, mint camphor, borneol, 75% ethanol, eucalyptus oil, peppermint, PEG4000 and PEG6000. Compared with the prior art, the throat lozenge provided by the invention has the efficacies of clearing heat from throat, eliminating tumescence and killing pain, and can be used for preventing and treating sore throat, hoarseness, pharyngitis, throat abscess, acute tonsillitis, aphthous stomatitis, mouth and tongue sore, periodontalabscess, acute and chronic pharyngitis, tonsillitis, mouth ulcers, stomatitis, swelling and aching of gum and the like.

The invention provides an externally applied ointment for adjuvant therapy of pharyngitis and canker sore. The externally applied ointment is characterized by comprising the following components in percentage by weight: 5 to 10 percent of gardenia, 5 to 15 percent of wild pepper, 15 to 35 percent of amur corktree bark, 15 to 45 percent of honeysuckle flower and 15 to 45 percent of mint. A preparation method of the externally applied ointment comprises the following steps of: removing impurities; cleaning; drying; grinding; sieving; and decocting to form the ointment. The ointment has the various effects of clearing away heat, reducing fire, clearing away toxic materials, treating sore throat, aphtha, toothache, skin and external diseases, mute, lichen planus, aphthous stomatitis, sore and pyogenicinfections, trauma infection, scabies and urticaria, disinfesting insect, easing anger, removing toxin, making mouth smell sweet and clean and the like, and can treat the toothache and external swelling and pain symptom.

Compositions for the treatment of some orphan diseases and oral mucosal ulcers, many with similarities in terms of their anti-inflammatory and anti-oxidative activities, but also multiple differences in their observed abilities that can be combined to challenge the current, underlying pathophysiology. The orphan diseases of interest are Dupuytren's Contracture, Peyronie's Disease, Scleroderma, Raynaud's (or Renaud's) Phenomenon, chemotherapy / radiation induced oral mucosal ulceration, and aphthous ulcers; and more frequent skin issues of skin damage from cuts, abrasions, and burns; aging skin changes, and toe nail fungus. These can be treated with the disclosed compositions with the proper combination and alteration of ingredients:

.The invention discloses a traditional Chinese medicine for treating the recurrent oral ulcer. The recurrent oral ulcer belongs to the fields of aphthae, aphthous stomatitis and the like in the traditional Chinese medicinal science, and the clinical manifestations of the recurrent oral ulcer mainly comprise skin and mucosal ulcer impairment. Traditional Chinese medicines comprising Souliea vaginata, nervos brake herb, Meadowrue Root and Rhizome, root of Cynoglossumfurcatum Wall., Entireleaf Neoalsomitra, Vietnamese Sophora Root, Natural Indigo, Pyrethrum tatsienense, Euphorbia humifusa Willd, Bigleaf Beautyberry Leaf, catechu, red halloysite, Rhizoma Panacis Majoris, selenitum and all-grass of Climbing Hedyotis are processed in the preparation department of the hospital in which the inventor of the invention works to prepare a decoction. The result of clinic tests shows that the total effective rate of the composition is 96.9% and is obviously higher than that of a contrast group, so the curative effects of the composition are good.

Methods and devices for effectively treating aphthous ulcers are disclosed. The invention employs the removal of the plaque layer of the aphthous ulcer to accelerate healing. Before the plaque layer is removed, the ulcer may be initially anesthetized, by rubbing with an appropriate material and / or compound. Subsequently, an appropriate medicament may be applied to accelerate healing, if desired. The invention teaches the structure and use of applicator / dispenser system employing easily crushable ampoules, containing an aesthetic, and other appropriate medicaments. The invention further teaches the application of slippery surfaces to teeth, teeth appliances, and oral cavity surfaces to inhibit the generation of aphthous ulcers, and to speed their healing. The application, in the form a gel or film, may include a sustained release medicament. Finally, the invention contemplates the use of replaceable and disposable tips for power toothbrushes and the like to aid the treatment of the aphthous ulcers, and the use of dendrimer technology to provide sustained and concentrated local drug action.

Pharmaceutical compositions are provided which comprise effective amounts of antimicrobials, anti-inflammatories, and antihistamines, to provide an ulcer medication which prevents secondary infections and promotes healing while providing immediate relief from pain. The composition may be used to treat a variety of ulcers including but not limited to intraoral aphthous ulcers and non-oral lesions. The compositions of the present invention may also be combined with materials capable of forming seals over ulcers or lesions to further promote the healing process.

The invention relates to a Chinese medicine preparation for treating oral diseases, which is applicable to treating canker sore and aphthous stomatitis. The medicinal preparation for the oral cavity comprises tree peony bark extract and peppermint oil in the form of candy tablet and buccal tablet preferably, and has the advantages of convenient application and slight side effect. The tree peony bark is subject to supercritical fluid extraction to gain the end products in high peppermint oil content and long retention time and lasting effect. The preparation is characterized by uniform slow release as the product is thawed in the oral cavity bit by bit, and has gentle and comfortable effect.

Compositions for the treatment of some orphan diseases and oral mucosal ulcers, many with similarities in terms of their anti-inflammatory and anti-oxidative activities, but also multiple differences in their observed abilities that can be combined to challenge the current, underlying pathophysiology. The orphan diseases of interest are Dupuytren's Contracture, Peyronie's Disease, Scleroderma, Raynaud's (or Renaud's) Phenomenon, chemotherapy / radiation induced oral mucosal ulceration, and aphthous ulcers; and more frequent skin issues of skin damage from cuts, abrasions, and burns; aging skin changes, and toe nail fungus. These can be treated with the disclosed compositions with the proper combination and alteration of ingredients inclusive of alpha-pinene, an aloe vera preparation, and a shea butter preparation. A process for preparation of such ingredients in a water-in-oil emulsion is described herein.

The present invention relates to compositions comprising a lipophilic local anaesthetic, preferably bupivacaine or a pharmaceutically active salt thereof, which are formulated for local administration to the mouth or throat of a subject. The compositions are useful in the treatment or alleviation of pain, burning or xerostomia of the oral cavity, pharynx, oral mucosa and pharyngeal mucosa or for use in providing local anesthesia of the oral cavity, pharynx, oral mucosa and pharyngeal mucosa. In particular in the treatment of pain, burning or xerostomia, which is caused by a disease such as oral mucositis, Burning Mouth Syndrome, Sjogren's syndrome, xerostomia, periodontitis, toothache, tonsillectomy, throat infection or mononucleosis, canker sores and aphthous stomatitis.

An ultrasonic toothbrush having spatially extended functionality to treat various oral diseases in addition to removing plaque and treating gingivitis is disclosed. In addition to the ultrasonically activated bristles, the toothbrush incorporates a multi directional ultrasound transducer system, which spatially irradiates the oral cavity with ultrasonic pressure waves, operational to loosen plaque, to remove periodontal bacteria from teeth and gums, and to simultaneously treat and destroy disease causing bacteria and bacterial chains on the inside surfaces of cheeks and lips, providing relief from Recurring Aphthous Stomatitis, Lichen Planus, and Mucositis. Various configurations are disclosed, including user removable and replaceable brush heads, ultrasound treatment heads, and a system of protecting the vibrating exposed ultrasound transducer from contacting the teeth of the user. A motorized version featuring sonic frequency orbital vibration brush head and bristle tufts is described.

The present invention relates to compositions comprising a lipophilic local anaesthetic, preferably bupivacaine or a pharmaceutically active salt thereof, which are formulated for local administration to the mouth or throat of a subject. The compositions are useful in the treatment or alleviation of pain, burning or xerostomia of the oral cavity, pharynx, oral mucosa and pharyngeal mucosa or for use in providing local anesthesia of the oral cavity, pharynx, oral mucosa and pharyngeal mucosa. In particular in the treatment of pain, burning or xerostomia, which is caused by a disease such as oral mucositis, Burning Mouth Syndrome, Sjogren's syndrome, xerostomia, periodontitis, toothache, tonsillectomy, throat infection or mononucleosis, canker sores and aphthous stomatitis.

Provided by the present invention are topical formulations of Interleukin-11 and methods for treating a variety of disorders, including inflammatory bowel diseases (e.g., Crohn's disease, ulcerative colitis, indeterminate colitis, and infectious colitis), mucositis (e.g., oral mucositis, gastrointestinal mucositis, nasal mucositis, and proctitis), necrotizing enterocolitis, inflammatory skin disorders (e.g., psoriasis, atopic dermatitis, and contact hypersensitivity), aphthous ulcers, pharyngitis, esophagitis, peptic ulcers, gingivitis, periodontitis, and ocular diseases (e.g., conjunctivitis, retinitis, and uveitis).

The present invention is related to a use for treating and preventing inflammation related disorder of a composition containing a drug and hyaluronic acid (HA) or HA mixture, whereas the HA or the HA mixture as a delivery vehicle can be a formulation including at least two HAs having different average molecular weights. The composition has been demonstrated to be capable of reducing the therapeutic dose of a drug on the treatment and prevention of inflammation related disorders is acute inflammatory disease, chronic obstructed pulmonary disease, coeliac disease, conjunctivitis, otitis, allergic rhinitis, gingivitis, aphthous ulcer, bronchitis, gastroesophageal reflux disease (GERD), esophagitis, gastritis, enteritis, peptic ulcer, inflammatory bowel disease (IBD), Crohn's Disease, irritable bowel syndrome (IBS), intestinal inflammation or allergy, urethritis, cystitis, vaginitis, proctitis, eosinophilic gastroenteritis, or rheumatoid arthritis.

The invention discloses a multipurpose traditional Chinese medicine formula and a decocting method thereof. The multipurpose traditional Chinese medicine formula comprises the following components in percentage by weight: 3-5 grams of radix aconiti carmichaeli, 9-11 grams of radix rehmanniae praeparata, 8-10 grams of fructus corni, 14-16 grams of rhizoma dioscoreae, 9-10 grams of medlars, 10-11 grams of rhizoma cibotii, 8-11 grams of cortex eucommiae, 9-11 grams of walnut meat, 8-10 grams of angelica sinensis, 10-11 grams of radix morindae officinalis, 8-10 grams of fructus psoraleae, 9-11 grams of codonopsis pilosula, 15-16 grams of radix astragali, 9-11 grams of bighead atractylodes rhizome, 3-5 grams of cortex cinnamomi and 10-12 grams of deer horn cornu cervi. The prescription is a kidney essence deficiency yang prescription, can be used for multiple diseases, such as gastralgia, headache, paralysis, cervical spondylosis, night sweat, nosebleed, osteoporosis, dim eyesight, tonsillitis, gingival abscess, aphthous stomatitis and alopecia and has very good curative effect on treating various diseases caused by kidney essence deficiency. The multipurpose traditional Chinese medicine formula disclosed by the invention is prepared by adopting pure traditional Chinese medicines and has the advantages of short treatment period, outstanding effect and small side effect.

The invention relates to a chrysanthemum and fructus lycii wall-broken composition and a preparing method and application thereof. The wall-broken composition is prepared from, by weight, 1-10 parts of chrysanthemum and 1-12 parts of fructus lycii through wall breaking and freeze-drying granulating, wherein the granularity of the wall-broken composition is 20-80 meshes. Fructus lycii and chrysanthemum which are clinically and frequently used for preventing and improving asthenopia and other symptoms are selected for the wall-broken composition, and the wall-broken composition has the effects of tonifying livers and kidneys and improving the eyesight, and is suitable for blurred vision caused by deficiency of liver-yin and kidney-yin, hyperactivity of liver-yang and other reasons. In addition, the wall-broken composition has a certain preventing and treating effect on recurrent aphthous ulcer and can relieve aphthous ulcer symptoms and delay recurrence time. The wall-broken compositiongranules which completely do not break the original components and have a specific granularity are successfully prepared through the preparing method by means of the freeze-drying granulating and other special processes, and the composition is simple and practical in process, low in cost, high in effective component content, suitable for industrial production and application and good in market prospects.

The invention relates to the field of traditional Chinese medicine, in particular to an ointment for the treatment for oral ulcer and oral aphthae and erosion in children and a preparation method thereof. The ointment comprises the following components: white honey, red lead, stiff silkworm and borneol, and the mix ratio by weight is as follows: 400 to 600g of white honey, 40 to 60g of red lead, 5 to 20g of stiff silkworm and 5 to 20g of borneol. The stiff silkworm and the borneol are firstly porphyrized, then the white honey, the red lead, the bornel and the silkworm are placed in a porcelain basin for even stirring and then placed in a pot for steaming till black, finally placed in a bottle for standby and then can be readily used. The invention has the advantages that: the ointment prepared by the invention has convenient usage, safety, reliability, no toxicity or side effect, fast efficacy, good effect, high cure rate and effective rate of 100 percent.

The invention provides herba corydalis saxicolae tea. The herba corydalis saxicolae tea is prepared from, by weight, 20-40 parts of herba corydalis saxicolae, 20-40 parts of sweet tea, 20-40 parts of fructus momordicae and 20-40 parts of licorice roots, wherein the weight parts are metered by the dry raw materials with the water content not exceeding 10%. The herba corydalis saxicolae tea has the effects of clearing away heat and toxic materials, promoting diuresis, moistening the lung to benefit the throat and expelling phlegm to arrest coughing, can treat hepatitis, aphthous stomatitis, sphagitis, amygdalitis, an eye inflammation, slight corneal opacity, dysentery, diarrhea, abdominal pain, acute gastritis, constipation, hemorrhoidal bleeding and the like and also has the nutrition and healthcare effects; in addition, due to the fact that the herba corydalis saxicolae tea belongs to a sugar-free product, the herba corydalis saxicolae tea is specially suitable for obese people and diabetic patients and can reduce weight and fat, and patients suffering from cardiovascular diseases, obesity, diabetes and the like all can drink the tea; the herba corydalis saxicolae tea is good in mouthfeel and convenient to take and can be drunk by being directly brewed with boiling water. The invention further provides a preparation method of the herba corydalis saxicolae tea.

Provided by the present invention are topical formulations of Interleukin-11 and methods for treating a variety of disorders, including inflammatory bowel diseases (e.g., Crohn's disease, ulcerative colitis, indeterminate colitis, and infectious colitis), mucositis (e.g., oral mucositis, gastrointestinal mucositis, nasal mucositis, and proctitis), necrotizing enterocolitis, inflammatory skin disorders (e.g., psoriasis, atopic dermatitis, and contact hypersensitivity), aphthous ulcers, pharyngitis, esophagitis, peptic ulcers, gingivitis, periodontitis, and ocular diseases (e.g., conjunctivitis, retinitis, and uveitis).