Chrysanthemum and fructus lycii wall-broken composition and preparing method and application thereof

A technology of lycium barbarum wall breaking and composition, which is applied in the directions of drug combination, food science, pharmaceutical formulation, etc., can solve the problems of low utilization rate and poor effect, and achieves prolonging the recurrence time, relieving the symptoms of aphthous ulcers, preventing and improving visual acuity. effect of fatigue

Active Publication Date: 2018-05-18
ZHONGSHAN ZHONGZHI PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to overcome the defects and deficiencies of poor efficacy and low utilization rate of traditional Chinese medicine prescriptions for visual fatigue in the prior art, and to provide a wall-breaking composition of chrysanthemum and medlar

Method used

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  • Chrysanthemum and fructus lycii wall-broken composition and preparing method and application thereof
  • Chrysanthemum and fructus lycii wall-broken composition and preparing method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0041] The wall-breaking composition of chrysanthemum and medlar provided in this example is prepared from 1 part of chrysanthemum and 12 parts of medlar. The specific preparation method is as follows:

[0042](1) Lycium barbarum flowers were refrigerated in the refrigerator for 36 hours until the temperature was -30°C, and chrysanthemums were refrigerated in the refrigerator for 12 hours until the temperature was 4°C.

[0043] (2) Start the wall-breaking grinder and force the cooling to -30°C in advance, add the aforementioned cooled chrysanthemum and medlar raw materials, break the wall and grind for 15 minutes, and grind until the D90 is 20-75 μm.

[0044] (3) In the rotary roller press freeze-drying granulator, set the roller speed at 30rpm, the pressure at 90bar, the two-stage granulation speed at 180rpm, keep the temperature of the broken wall powder at -10°C, and the relative humidity at 20%. Composition granules of 20 to 80 meshes are placed in an air-refreshing room. ...

Embodiment 2

[0046] The wall-breaking composition of chrysanthemum and medlar provided in this example is prepared from 10 parts of chrysanthemum and 1 part of medlar. The specific preparation method is as follows:

[0047] (1) Lycium barbarum flowers were refrigerated in the refrigerator for 12 hours until the temperature was -5°C, and chrysanthemums were refrigerated in the refrigerator for 36 hours until the temperature was 0°C.

[0048] (2) Start the wall-breaking grinder and force the cooling to -15°C in advance, add the aforementioned cooled chrysanthemum and medlar raw materials, break the wall for 45 minutes, and grind until the D90 is 20-75 μm.

[0049] (3) In the rotary roller press freeze-drying granulator, set the roller speed at 9rpm, the pressure at 200bar, the two-stage granulation speed at 70rpm, keep the temperature of the broken wall powder at 0°C, and the relative humidity at 5%, and granulate to 20 ~80 mesh composition granules, and then put them in an air-refreshing ro...

Embodiment 3

[0051] The wall-breaking composition of chrysanthemum and medlar provided in this example is prepared from 3 parts of chrysanthemum and 10 parts of medlar. The specific preparation method is as follows:

[0052] (1) Lycium barbarum flowers were refrigerated in the refrigerator for 24 hours until the temperature was -20°C, and chrysanthemums were refrigerated in the refrigerator for 24 hours until the temperature was 0°C.

[0053] (2) Start the wall-breaking grinder and force the cooling to -20°C in advance, add the aforementioned cooled chrysanthemum and medlar raw materials, break the wall and grind for 30 minutes, and grind until the D90 is 20-75 μm.

[0054] (3) In the rolling-type freeze-drying granulator, set the roller speed at 22rpm, the pressure at 130bar, the two-stage granulation speed at 110rpm, keep the temperature of the broken wall powder at -5°C, and the relative humidity at 10%. Composition granules of 20 to 80 meshes are placed in an air-refreshing room. The t...

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Abstract

The invention relates to a chrysanthemum and fructus lycii wall-broken composition and a preparing method and application thereof. The wall-broken composition is prepared from, by weight, 1-10 parts of chrysanthemum and 1-12 parts of fructus lycii through wall breaking and freeze-drying granulating, wherein the granularity of the wall-broken composition is 20-80 meshes. Fructus lycii and chrysanthemum which are clinically and frequently used for preventing and improving asthenopia and other symptoms are selected for the wall-broken composition, and the wall-broken composition has the effects of tonifying livers and kidneys and improving the eyesight, and is suitable for blurred vision caused by deficiency of liver-yin and kidney-yin, hyperactivity of liver-yang and other reasons. In addition, the wall-broken composition has a certain preventing and treating effect on recurrent aphthous ulcer and can relieve aphthous ulcer symptoms and delay recurrence time. The wall-broken compositiongranules which completely do not break the original components and have a specific granularity are successfully prepared through the preparing method by means of the freeze-drying granulating and other special processes, and the composition is simple and practical in process, low in cost, high in effective component content, suitable for industrial production and application and good in market prospects.

Description

technical field [0001] The invention relates to the field of wall-breaking compositions, in particular to a wall-breaking composition of chrysanthemum and medlar fruit and its preparation method and application. Background technique [0002] Eye fatigue is a series of eye discomfort symptoms caused by excessive eye use (including: reading documents, operating computers, surfing the Internet, watching TV, driving, etc.) and environmental factors (dry climate, air-conditioned environment, etc.), mainly manifested as dry eyes, Foreign body sensation, blurred vision, eye soreness, etc. Most ophthalmologists now believe that visual fatigue is based on the patient's conscious eye symptoms, and is a syndrome in which organic factors of the eye or the whole body are intertwined with mental factors. Therefore, it is often called visual fatigue syndrome and belongs to the category of physical and mental medicine. Seriously affected the patient's study, work and life. Traditional Chi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61K9/16A61P27/02A61P1/02A23L33/00
CPCA61K9/16A61K36/287A61K36/815A61K2236/15A23L33/00A61K2300/00
Inventor 陈勇军成金乐徐吉银邓雯陈炜璇彭丽华乔卫林唐琳马宏亮陈炯刘子超陈金梅朱丹烨梁燕玲劳悦富王义娜
Owner ZHONGSHAN ZHONGZHI PHARMA GRP
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