The invention relates to the technical field of oral thick paste preparation processes, in particular to an oral thick paste with an asthenopia relieving effect, the oral thick paste raw materials comprise core raw materials, the core raw materials comprise, by weight, 3-8 parts of chrysanthemum, 0.5-3 parts of
dendrobium officinale, 3-8 parts of Chinese wolfberry, 3-8 parts of poria cocos, 3-8 parts of black sesame and 1-3 parts of prebiotics; the decoction process of the oral thick paste sequentially comprises the steps of pretreatment, extraction, concentration and paste collection, a step-by-step extraction mode or an enzymolysis-assisted extraction mode is adopted in the extraction step, or a mode of combining
supercritical fluid extraction with
water extraction is adopted in the concentration step, a gradient concentration mode and a
microwave-assisted concentration mode are adopted in the concentration step, and an ultrasonic-assisted paste collection mode is adopted in the paste collection step. The
eye protection effect is more comprehensive, prebiotics, blueberries, mulberries and the like are further introduced, and medicinal and edible components such as
codonopsis pilosula, lily and the like are further introduced in the scheme and have a synergistic effect with other raw materials, so that a multi-target
eye protection system for regulating intestinal tracts and nourishing eyes is constructed.