231 results about "Edetate disodium" patented technology

The invention discloses an anti-oxidation metal surface treating agent. The anti-oxidation metal surface treating agent is prepared from, by weight, 0.4-0.5 part of borax, 40-50 parts of polyvinyl alcohol, 12-15 parts of polyethylene glycol, 0.4-0.6 part of emulsifier op10, 0.3-0.5 part of glycerol, 0.6-0.8 part of triethanolamine, 6-8 parts of benzotriazole, 6-7 parts of sodium benzoate, 2-3 parts of sodium dodecyl sulfate, 0.4-0.6 part of butanedial, 4-5 parts of nano-crystalline cellulose, 0.3-0.4 part of diethylenetriamine, 0.32-0.4 part of vinyl trimethoxy silane, 0.2-0.3 part of polyvinylpyrrolidone, 1.2-1.6 parts of copper powder, 0.8-1.2 parts of catechin, 0.4-0.6 part of edetate disodium and a proper amount of deionized water. The prepared metal surface treating agent has the advantages that a preparation method is simple, cost is low, film forming performance is good, after-treatment is easy, the surface treating agent has good anti-oxidation, anti-rust and anti-corrosion functions on a metal surface, the effect is good, and application prospects are good.

The invention discloses a drug composition containing a lansoprazole compound, which comprises the following raw materials in parts by weight: 10-20 parts of lansoprazole, 1-10 parts of edetate disodium, 1-20 parts of mannitol, 5-10 parts of sodium sulfite and 10-30 parts of sodium citrate. According to the drug composition, a pH regulator sodium citrate is screened out by a large number of tests and compounded with a stabilizing agent edetate disodium, the synergistic interaction is obvious; decrease of a pH value of strongly basic lansoprazole solution during production or a lyophilized agent during storage can be avoided well; therefore, re-dissolution of the lansoprazole lyophilized agent can be well avoided; and the solubility is good. The drug composition does not go bad and is not oxidized in a storage process, and the administration safety is ensured.

The invention belongs to the field of medicine detection, and discloses a content determination method of edetate disodium in acetylcysteine liquid preparation. In the method, HPLC is used, a test solution is prepared from the acetylcysteine liquid preparation, cyclodextrin and / or cyclodextrin derivatives, Fe3+ and a mobile phase, amino silane bonded silica gel is used as a chromatographic columnof a filler, a mixed solvent of ion pair buffer solution and an organic phase is used as the mobile phase, and thus, content of the edetate disodium in the test solution can be determined. The methodis simple to operate and excellent in repeatability, can accurately determine content of the edetate disodium in the acetylcysteine liquid preparation, and consequently can control product quality ofthe edetate disodium in acetylcysteine liquid preparation better.

The invention discloses a composite material for yoga balls and a preparation method of the composite material. The composite material is prepared from the following components in parts by weight: 40-55 parts of PVC, 1-5 parts of an antiager, 12-18 parts of a carbon fiber, 5-12 parts of rubber powder, 5-9 parts of edetate disodium, 1-5 parts of glycerin, 0.1-0.5 part of talcum powder, 3-6 parts of olive oil, 1-6 parts of molding powder and 0.2-0.5 part of acetic acid. The preparation method comprises the following steps: step 1, mixing PVC, rubber power, talcum powder and molding powder, putting the mixed components into a grinder for grinding, and carrying out screening to obtain a mixture I; adding the carbon fiber, edetate disodium, glycerin and acetic acid into the mixture I for stirring and transferring into a reaction kettle, and carrying out vacuum heating to enable the temperature to be 200-350 DEG C to obtain a mixture II; spraying olive oil into the mixture II for stirring and transferring into a pelletizer for pelletization, thereby obtaining the composite material. The composite material is high in elasticity, resistant to abrasion and brushing, and wide in application range.

The invention discloses a preparator of a naloxone hydrochloride injection and a preparation method thereof. The preparation method comprises the steps that a certain amount of water for injection, sodium chloride and naloxone hydrochloride are added into an upper tank body of the preparator, nitrogen is introduced, mixing and stirring are performed to obtain a mixed solution, then edetate disodium is added to regulate a pH value, and the mixed solution is filtered by a first filter membrane in the middle of the preparator and delivered to a lower tank body; a certain amount of water for injection is added into the lower tank body, stirring is performed under the situation that nitrogen is introduced, and a hydrochloric acid solution is used for regulating the pH value; finally, visible foreign matter checking is performed after filtration of a second filter membrane at the lower portion of the lower tank body, nitrogen charging is performed for filling encapsulation after qualification, and sterilization is performed to obtain the sterilization. No auxiliary material is added, and the purity and use safety of the prepared injection are ensured. The preparation method is simple and easy to operate, and the preparation cost is effectively reduced. In addition, the invention provides the preparator of the naloxone hydrochloride injection. Device replacement in the preparation process of the naloxone hydrochloride injection is avoided, the drug quality is improved, and drug safety is ensured.

A powder injection of composite VB for intravenous injection is prepared from VB1, riboflavine sodium phosphate, VB6, nicotinic amide, sodium dextropantothenate, edetate disodium, low-molecular dextran and excipient through pretreating, proportional mixing, filtering for removing bacteria, and freeze drying.