The invention discloses spot-removing cream. The spot-removing cream is composed by the following raw materials: ceto-stearyl alcohol, dimethyl silicone oil, white mineral oil, caprylic/capric triglyceride, echium lycopsis oil, triclosan, vitamin E, water, glycerin, xanthan gum, an amino acid moisturizing agent, sodium hyaluronate, an anchoic acid derivative, paeonol, glabridin, propylene glycol and supguard GM-BP. In the formula of the spot-removing cream, the anchoic acid derivative and paeonol act collectively, thereby eliminating tingling caused by adopting the anchoic acid derivative individually, broadening blood capillary of skins, promoting blood circulation and enhancing defense capability of the skins; in combination with glabridin and vitamin E, activities of tyrosinase, hallachrome tautomerase can be inhibited, hyperpigmentation can be alleviated, and spot-restraining and skin whitening effects are enhanced; and the existence of the amino acid moisturizing agent and echium lycopsis oil allows the spot-removing cream to have the functions of moisturizing and resisting inflammation and anaphylaxis.