5 results about "Skin immunity" patented technology

The invention belongs to the technical field of cosmetics, and particularly relates to a composition with a skin protection effect and application thereof. Specifically, the invention provides the composition with skin protection effects of resisting blue light, improving skin immunity, regulating skin mood pressure and the like for the first time, the composition comprises supernate of animal bifidobacterium W3 fermentation liquor and porphyra haitanensis extract, and the supernate and the porphyra haitanensis extract have a synergistic effect. The composition has the effects of resisting blue light, improving skin immunity and regulating skin mood pressure by recovering the cell viability level under blue light damage, increasing the expression quantity of VDR mRNA in skin, increasing the expression quantity of mRNA of antibacterial peptide LL-37 and increasing the content of beta-enorphin, and has good practical application value.

The present application relates to a kind of skin care composition and its application for quickly relieving sensitive skin hot red, enhancing skin tolerance, belong to the field of cosmetics.The raw materials of the skin care composition include schisandra chinensis extract, stachyose, Cynara scolymus leaf extract, red clover flower extract and citrus fruit extract five kinds of active ingredients, through the cross regulation of multiple target signal pathways, the complementary synergies of different action links and the overall coordination of metabolic network, form the synergistic amplification effect of "heat elimination and detoxification, slow down hot feeling, converge pores, enhance skin immunity".

This invention belongs to the field of daily chemical products and discloses a polysaccharide composition that improves skin immunity and strengthens the skin barrier function, as well as its applications. The polysaccharide composition includes Scutellaria baicalensis polysaccharide, Adenophora stricta polysaccharide, and Trametes versicolor polysaccharide. Through the synergistic effect of these three polysaccharides, it can not only reduce the number of mast cells but also increase antimicrobial peptides and filaggrin; increase filaggrin; and decrease monocyte chemotactic protein-1 and interleukin-6, thereby achieving the effects of improving skin immunity, anti-inflammatory and whitening. Furthermore, it can act as a signaling molecule, widely participating in physiological processes such as intercellular ligand-receptor recognition and intercellular signal transduction, reducing the average relative amplification fold of interleukin-6 expression factor mRNA, and effectively participating in epidermal cell differentiation and skin barrier formation, thus strengthening the skin barrier function; it can be used in the preparation of cosmetics.

The present application relates to a kind of compositions for improving skin immunity and skin barrier function and its preparation method and application, belong to cosmetic technical field.The composition for improving skin immunity and skin barrier function, including the weight ratio of 1-4:0.5 aspartic acid polysaccharide and aspartic acid active peptide;Wherein, the aspartic acid polysaccharide can promote fibroblast proliferation, macrophage secretion anti-inflammatory factor, can enhance the active defense ability of skin, and have significant antioxidant capacity;The aspartic acid active peptide has the effect of promoting human skin fibroblast activity, cell proliferation, resisting oxidative damage.The aspartic acid polysaccharide and aspartic acid active peptide are compounded according to specific amount ratio in the present application, can synergistically promote the secretion of barrier repair related protein (i.e.silk aggregate protein and shikin protein), effectively regulate skin immune homeostasis, improve skin defense and barrier repair capacity.

Aspects of a microneedle array containing a metal-organic structure (MOF)-vaccine biocomposite and a method for using the same are disclosed herein. The microneedle array further comprises a soluble material that dissolves when inserted into the skin of a subject, thereby releasing the MOF-vaccine biocomposite. The MOF may dissolve in an acidic environment, thereby being selected to target vaccine delivery to specific cellular compartments. Methods for preparing the MOF-vaccine biocomposite and the microneedle array are also disclosed.