The application discloses an artificial
fascia which is a
composite material with a five-layer structure and is composed of fat
stem cell-loaded amniotic membrane, PRP gel and
polyurethane film; the five-layer structure material is in sequence of fat
stem cell-loaded amniotic membrane, PRP gel,
polyurethane film, PRP gel and fat
stem cell-loaded amniotic membrane; the fat stem
cell-loaded amniotic membrane is acellular amniotic membrane paved with fat stem cells and is prepared by the following method: inoculating fat stem cells on the acellular amniotic membrane and growing for 7-14 days to obtain the fat stem
cell-loaded amniotic membrane. The application further discloses a preparation method of the artificial
fascia and application of the artificial
fascia in preparation of a biological patch for treating
hernia or in preparation of a mesh for treating
pelvic organ prolapse. The artificial fascia has high tensile strength, good
tissue compatibility, good immune function and degradability, is a biological
composite material with excellent performance, can be used for treating
hernia and
pelvic organ prolapse and has great application potential.