56results about How to "Promote ingrowth" patented technology

The invention discloses an adhesive hydrogel for oral periodontal tissue regeneration and a preparation method thereof, gelatin and polyacrylic acid are used as main raw materials, and a photo-crosslinking method is used as a basis to prepare the adhesive hydrogel; the adhesive hydrogel has good tissue adhesion, can be tightly adhered to wet soft and hard tissue surfaces, and overcomes the defect that the oral periodontal filling material is difficult to fix clinically at present. The adhesive hydrogel has high porosity after completely absorbing water and swelling, and pores in the surface and inside of the adhesive hydrogel are communicated with each other, so that the adhesive hydrogel can provide more space for growth of oral periodontal tissues, and is suitable for ingrowth of cells and regeneration of the oral periodontal tissues.

The invention provides a novel TPMS porous structure interbody fusion cage, and relates to the technical field of medical materials. The interbody fusion cage is designed by using a porous frame structure with different unit cell sizes and porosities, so that the biocompatibility of the interbody fusion cage is enhanced, the interbody fusion cage has higher mechanical properties, large static compression load and low elastic modulus, the elastic modulus is closer to that of human cortical bones, the stability of an implant in the early stage of osseointegration is improved, and the interbody fusion cage is suitable for being used in the field of osteosynthesis. Under the same porosity, the elastic modulus is lower, and the comprehensive performance is excellent.

The invention provides a preparation method of a gradient bionic rotator cuff repair stent, the stent prepared by the method and application. The method comprises the following steps that 1, a gradient fiber structure is designed through conventional 3D modeling software; step 2, adding the raw materials into the barrel material, and printing a tendon scaffold by adopting a near-field direct-writing melting technology; 3, raw materials in the barrel material are replaced, and the cartilage scaffold is printed through the near-field direct-writing melting technology; optionally, replacing the raw materials in the barrel material, and printing the mineralized cartilage scaffold by adopting a near-field direct-writing melting technology; and 4, replacing the raw materials in the barrel material, and printing the bone scaffold by adopting a near-field direct-writing fusion technology. The stent disclosed by the invention has a structural gradient and a component gradient, is matched with natural bone tissues, and can better promote the repair of the bone tissues.

The present invention provides a method for preparing a keratinized gingival repair scaffold, wherein the active powder of biological microspheres is dispersed in a protein slurry to obtain a loose surface stock solution, which is freeze-dried together with a cell-free matrix material, and after two cross-linkings, a keratinized gingival repair scaffold with a loose surface and a dense surface is obtained. When in use, the loose surface of the porous sponge structure contacts the wound surface, which is conducive to the attachment and growth of tissue cells, and the dense surface can seal and protect the wound to a certain extent in an open healing environment. The obtained keratinized gingival repair scaffold can effectively maintain and regulate the pH environment in the oral cavity, inhibit bacteria and resist bacteria, and inhibit the growth of acid-producing bacteria such as Streptococcus mutans and bacteria with strong caries-causing properties, and at the same time has the ability to stop bleeding, promote bone growth and periodontal ligament regeneration, and inhibit periodontal epithelial regression.

The invention relates to an absorbable double-layer membrane for guiding oral gingival tissue regeneration and repair and a preparation method thereof, the double-layer membrane comprises a compact layer and a loose layer, the compact layer is formed by PCL fibers, and the loose layer is formed by recombinant collagen / polyhydroxyalkanoate blend fibers. Wherein the PCL compact layer can be well stitched, and plays a protective role during open type healing. The recombinant collagen / polyhydroxyalkanoate blend fiber loose layer solves the problems of hydrophobicity of polyhydroxyalkanoate and low strength and too fast degradability of single recombinant collagen, and is more beneficial to fixation of blood clots and ingrowth of soft tissue cells, and inflammatory response is reduced. According to the double-layer membrane disclosed by the invention, the degradation time and the strength are highly matched with gingival tissues by optimizing the components, the proportion and the like, so that the regeneration and the repair of the gingival tissues can be better promoted, and the double-layer membrane has a remarkable clinical application value.

The invention discloses an orthopedic implant with antibacterial and osteogenesis-promoting characteristics and a preparation method thereof, and belongs to the technical field of medical materials.The preparation method comprises the steps that a titanium stent subjected to acid treatment is placed in a NaOH solution, and a sodium titanate coating is formed on the surface of the titanium stent after alkali heat treatment; after annealing, immersing into a mixed solution of EDTA-CaNa2 and NaH2PO42H2O, and after heating reaction, forming a hydroxyapatite coating on the surface of the sodium titanate coating; immersing the hydroxyapatite coating into a mixed solution of glucolactone and sodium alginate, controlling the pH value of the mixed solution to be 5, and forming a porous hydrogel coating on the surface of the hydroxyapatite coating after reaction; and soaking the loaded medicine to obtain the orthopedic implant. A multi-layer structure of the sodium titanate coating, the hydroxyapatite coating and the porous hydrogel coating is sequentially formed on the titanium alloy stent, and finally, the medicine is loaded, so that the titanium alloy stent has various characteristics of resisting bacteria, promoting osteogenesis and the like.

The invention relates to the technical field of biomedical materials, in particular to a bionic polyether-ether-ketone dental implant material and a preparation method thereof. The preparation method of the bionic polyether-ether-ketone dental implant comprises the following steps: mixing polyether-ether-ketone, a modified material and glass fibers in ethanol, and drying to respectively obtain composite powder of the modified material and the glass fibers in gradient change; the preparation method comprises the following steps: respectively pressing glass fiber / modified material / polyether-ether-ketone composite powder with different contents into composite powder discs, then stacking layer by layer according to the sequence of the contents of the glass fiber materials from high to low and the sequence of the contents of the modified materials from low to high, and forming to obtain a composite material biscuit; and cutting the composite material biscuit by using CAD / CAM according to a designed implant model to obtain the bionic polyether-ether-ketone dental implant. The invention provides a precise bionic polyether-ether-ketone dental implant material which is gradually changed from neck to root mechanics and aesthetics and has osteogenesis promoting and antibacterial properties.

The invention provides a bionic 3D printing degradable magnesium alloy interbody fusion cage and a preparation method thereof, the bionic 3D printing degradable magnesium alloy interbody fusion cage comprises a porous frame and a through hole net rack, the porous frame is constructed by supporting rods with the diameter of about 0.4 mm, the porous frame is of a compact rhombic hole structure, the aperture is about 200-400 microns, the pore coverage rate is about 50%-80%, and a horseshoe-shaped columnar space is defined; the through-hole net rack is formed by building supporting rods with the diameter of 0.2-0.1 mm, the hole diameter is about 300-800 microns, the hole coverage rate is about 90%, a dome structure is formed in the center, and the through-hole net rack is arranged in the middle of the porous frame. The magnesium-strontium alloy is adopted as a base material of the interbody fusion cage, the interbody fusion cage is integrally formed through the 3D printing technology, and the degradable characteristic and good biocompatibility of the magnesium alloy are fully utilized. The elasticity modulus of the magnesium alloy is closer to that of the human bone tissue, physiological loads can be better shared and transmitted, the stress shielding effect is reduced, and growth and fusion of the bone tissue are promoted.

The utility model belongs to the technical field of medical instruments, and particularly relates to a 3D printing lateral anterior approach interbody fusion cage which comprises an interbody fusion cage body and an insertion rod assembly arranged on the interbody fusion cage body, the insertion rod assembly comprises an insertion rod and a fixing block connected with one end of the insertion rod, and the insertion rod is arranged in an arc shape; the stability of the interbody fusion cage during initial implantation can be effectively improved through the insertion rod assembly, the interbody fusion cage is convenient to install, the fusion cage can be effectively prevented from falling off, the immediate stabilization effect is achieved, and the operation safety is improved; and the arc-shaped insertion rod facilitates installation of the insertion rod, the stability of the insertion rod can be improved, the fixing block connected with one end of the insertion rod can play a role in positioning, and the insertion rod is prevented from being hit too deep.

This invention discloses a hip joint prosthesis for bone defects, comprising a crescent-shaped acetabular rim filler assembly, a bone-metal defect block, an acetabular wall defect support block, a cylindrical support block, an angle pad, a locking screw, a locking nut, an assembly screw, an acetabular sealing screw, and an acetabular support block. The crescent-shaped acetabular rim filler assembly includes two sets of crescent-shaped acetabular rim fillers, which are assembled by engaging pins through pin holes. The outer circumference of the bone-metal defect block of the acetabular support block is connected to the crescent-shaped acetabular rim filler assembly via bone cement. This hip joint prosthesis for bone defects effectively fills irregular defect areas of the acetabular rim. The various screw holes and Kirschner wire holes on its surface provide multi-dimensional fixation options. The overall structure, through the synergistic action of multiple components, achieves precise reconstruction while ensuring biomechanical performance, significantly reducing the risk of postoperative prosthesis loosening and wear.

The application discloses a 3D printing ocular prosthesis platform, which is prepared through the following steps: S1, designing the shape of the ocular prosthesis platform and dividing the shape into regions; S2, selecting a porous structure for the ocular prosthesis platform in each region and determining the voxel size according to the connecting point parameters of the selected porous structure; S3, voxelizing and fitting each region to form a voxelized interface; S4, filling the porous structure selected in step S2 into each corresponding region to complete the modeling of the porous structure in each region; S5, connecting the connecting points on adjacent voxelized interfaces to each other and converting the connecting lines into solid rod models to complete the modeling of the interfaces; S6, merging the models obtained in steps S4 and S5 to obtain a final model of the ocular prosthesis platform; S7, 3D printing to obtain a bioceramic blank; and S8, high-temperature sintering of the blank to obtain a 3D printed ocular prosthesis platform after porcelain forming. The application can obtain a new 3D printed ocular prosthesis platform, which provides technical support for ocular prosthesis repair.

The present invention discloses an orthopedic implant with antibacterial and osteogenic properties and a preparation method thereof, which belongs to the technical field of medical materials. The titanium stent after acid treatment is placed in a NaOH solution, and a sodium titanate coating is formed on the surface of the titanium stent after alkaline heat treatment; after annealing, it is immersed in a mixed solution of EDTA-CaNa2 and NaH2PO4•2H2O, and a hydroxyapatite coating is formed on the surface of the sodium titanate coating after heating reaction; it is immersed in a mixed solution of gluconolactone and sodium alginate, and the pH of the mixed solution is controlled to be 5, and a porous hydrogel coating is formed on the surface of the hydroxyapatite coating after reaction; after immersion and loading of drugs, the orthopedic implant is obtained. The present invention sequentially forms a multilayer structure of a sodium titanate coating, a hydroxyapatite coating, and a porous hydrogel coating on a titanium alloy stent, and finally loads drugs, so that it has multiple properties such as antibacterial and osteogenic properties.

The invention relates to a composite material for stopping bleeding and promoting bone repair as well as a preparation method and application thereof, the composite material comprises a collagen-calcium magnesium phosphate mineralized skeleton with a porous microspace structure and a skeleton filler, and the skeleton filler comprises polyethylene glycol 2000 and polyethylene glycol 400. By improving the material structure and introducing the filler into the collagen-calcium phosphate magnesium mineralized skeleton with the porous microspace structure, the collagen-calcium phosphate magnesium mineralized skeleton can provide viscosity and plasticity, can be shaped into any required shape, can be tightly adhered to a bone wound surface and can stop bleeding by compression; meanwhile, the microspace structure of the skeleton is beneficial to ingrowth, proliferation and differentiation of bone healing cells, so that bone healing can be effectively promoted, and the limitation that a traditional bone repair material is single in function is improved.

The invention discloses a 3D printing porous medical titanium alloy and a preparation process thereof, and relates to the technical field of medical titanium alloys, and the preparation process comprises the following operation steps: S1, cleaning a 3D printing porous titanium alloy sample piece to obtain a 3D printing porous titanium alloy prefabricated piece; s2, primary micro-arc oxidation is conducted, specifically, the 3D printing porous titanium alloy prefabricated part is placed in electrolyte to be subjected to primary micro-arc oxidation, and a 3D printing porous titanium alloy prefabricated part A is obtained; s3, the 3D printing porous titanium alloy is subjected to acid treatment, and a 3D printing porous titanium alloy prefabricated part B is obtained; s4, secondary micro-arc oxidation is conducted, specifically, the 3D printing porous titanium alloy prefabricated part B is placed in electrolyte to be subjected to secondary micro-arc oxidation, and a 3D printing porous titanium alloy prefabricated part C is obtained; s5, the 3D printing porous titanium alloy prefabricated part C is cleaned; transferring into a fibroin solution, and taking out; and irradiating for 8-15 minutes under an ultraviolet lamp, cleaning and drying to obtain a finished product.

The invention discloses a radiotherapy positioner and a preparation method thereof, and belongs to the technical field of medical materials. The radiotherapy positioner is a solid circular ring, a solid cylinder, a hollow circular ring or a hollow cylinder; the solid circular ring, the solid cylinder, the hollow circular ring or the hollow cylinder is composed of a carbon fiber composite material matrix and a heavy metal coating or a heavy metal carbide coating on the surface of the carbon fiber composite material matrix. The radiotherapy positioner has the characteristics of X-ray permeability, no artifacts during examination, strong development, light weight, good stability, good biocompatibility and the like, and can optimize the radiotherapy range, accuracy and use dosage to the greatest extent, so that the target area sketching is more accurate, and the injury of radiotherapy to a patient is reduced.

The present application belongs to the field of foot and ankle surgical implant devices and biomedical material surface engineering technology, and discloses a tibial component of ankle prosthesis with a composite coating, which comprises: a metal substrate which is a bionic trabecular three-dimensional interconnected porous titanium alloy structure, the porosity is 50-80%, the average pore size is 400-900 mu m, and the connected porosity is greater than or equal to 85%, so that the elastic modulus is controlled in the range of 5-20 GPa, and is matched with the cancellous bone of the tibia; a composite functional coating is in situ grown on the surface of the metal substrate, and the composite functional coating comprises a bioactive layer and a functional ion doped layer. The tibial component of the present application comprises a porous titanium alloy metal substrate and a composite functional coating constructed in situ on the surface thereof, the porous titanium alloy substrate is designed in a bionic trabecular structure to form a three-dimensional interconnected porous structure, so as to provide an elastic modulus matched with the cancellous bone of the tibia and promote the growth of bone tissue.

The present invention relates to a wire anchor and a wire anchor kit. The wire anchor comprises a nail body and a suture fixing part connected to the first end of the nail body, the nail body is in the shape of a spiral spring, the opening of the nail body is arranged toward the suture fixing part, and a suture is fixed on the suture fixing part. After the nail body enters the bone hole under the drive of an external wire anchor driver, the nail body is compressed and deformed along the radial direction of the nail body. The present invention sets the nail body of the wire anchor in the shape of a spiral spring, so that after the wire anchor enters the bone hole, the nail body is compressed and deformed along the radial direction of the nail body, which will not cause the diameter of the bone hole to expand, thereby applying elastic force to the inner wall of the bone hole, making it difficult for the wire anchor to loosen or fall out. At the same time, the gap between the spiral springs facilitates the growth of bones into the spiral springs, so that the wire anchor is better combined with the bone.

The present invention discloses a support rod for femoral head necrosis, characterized in that it comprises a head section rod and a tail section rod, the center of the head section rod is provided with a head section inner hole, the center of the tail section rod is provided with a tail section inner hole, the outer side wall of the tail section rod is provided with a first external thread, the outer side wall of the head section rod is provided with a first spiral groove, the inner side wall of the head section rod is provided with a first radial hole, and the first radial hole connects the first spiral groove with the head section inner hole. The present invention can provide sufficient support strength, and at the same time, in the early stage of implantation, all tissue fluid that causes increased internal pressure in the femoral head can flow out of the bone, and in the later stage of implantation, a certain space can be reserved for the growth of new bone cells, so that the patient can avoid femoral head collapse when walking normally, which is conducive to the growth of bone tissue and close combination with the support rod to increase mechanical properties. In addition, the present invention also discloses a method of use.

The present invention discloses a cervical fusion device, which is made of porous tantalum; the structure of the cervical fusion device is a box-type structure; the upper surface of the cervical fusion device is convex, and the lower surface is straight; the cervical fusion device includes a central part and a peripheral wall, the central part is arranged in the middle of the cervical fusion device, and the peripheral wall is arranged around the central part; the peripheral wall is made of porous tantalum with a porosity of 20%-30%; the central part is made of porous tantalum with a porosity of 70%-80%; the central part of the cervical fusion device is provided with vertically retractable barbs. The cervical fusion device provided by the present invention does not require bone grafting, has no bone grafting area, and avoids complications related to bone grafting; it is made of porous tantalum material. Porous tantalum, also known as trabecular metal, has a three-dimensional structure with interconnected pores similar to human cancellous bone, has a high porosity, can promote the exchange of nutrients in the pores, is more conducive to bone ingrowth, promotes bone integration, and increases the fusion rate.

The present invention provides an acetabular bone defect block and a hip joint replacement system, wherein the acetabular bone defect block comprises a defect block body (1), wherein the defect block body (1) comprises an inner surface (2) and an outer surface (3) protruding in the same direction, wherein the inner surface (2) is adapted to the outer surface of the acetabular cup, and the outer surface (3) is adapted to the acetabular bone defect surface, and the inner surface and the outer surface are independently surfaces larger than half of the arc surface. The acetabular bone defect block provided by the present invention can reduce the amount of bone loss during implantation, can automatically adapt to the acetabular cup or acetabular cup trial mold during surgery, is convenient for implantation operation, is convenient for installation, greatly reduces the difficulty of surgery and saves surgery time, has strong adhesion to the acetabular bone defect socket and the acetabular cup, and better maintains the stability of the implanted prosthesis.

The present invention belongs to the field of polymer materials, and in particular, relates to a method for preparing a porous polyethylene implant, comprising the following steps: a) melt-extrude polyethylene and then perform underwater granulation to obtain polyethylene particles with an average particle size of 300-800 μm; b) fill the polyethylene particles into a mold, sinter and form, and cool to obtain a porous polyethylene implant. The present invention first uses an underwater granulation process to prepare large polyethylene particles with a certain particle size, and then sinter these large polyethylene particles in a mold. During the sintering process, the large polyethylene particles contact and bond with each other to form abundant and large three-dimensional holes. The method of the present invention can be used to prepare a porous polyethylene implant with a larger pore size. The larger pore size can promote the growth of tissue cells, making the implant less likely to shift, and can also promote vascularization of the implant site and reduce the risk of infection.

The utility model discloses a joint prosthesis for hip replacement. The joint prosthesis comprises an acetabular cup body and a metal coating, the acetabular cup body is a polyetheretherketone hemisphere or a polyetheretherketone composite hemisphere, the acetabular cup body is hemispherical, and an inner surface used for mounting an acetabular cup lining and an outer surface used for mounting the acetabular cup body to an acetabular fossa of a human body are formed on the acetabular cup body; an annular lap joint groove is formed in the inner surface of the acetabular cup body and a port of the acetabular cup body, and the lap joint groove is used for fixing an acetabular cup lining. The metal coating is arranged on the outer surface of the acetabular cup body. According to the technical scheme, the acetabular cup body is made of the polyether-ether-ketone or the polyether-ether-ketone composite material, the material type of the acetabular cup body is similar to that of the acetabular cup lining, and abrasion of the acetabular lining is relieved. The metal coating can promote bone tissue to grow into the acetabular cup, the strength of the acetabular cup is improved, and the joint prosthesis has certain antibacterial ability. The arrangement of the metal coating reduces the release of metal ions on the premise of ensuring the precondition.

The present invention discloses a bone tissue engineering scaffold, including a hollow grid-shaped scaffold and a porous zinc-based metal ball filled therein, the porous zinc-based metal ball can be a solid ball with holes and grooves on the surface or a fluffy ball rolled by metal wire; an internal support column can also be arranged in the scaffold to provide more mechanical properties; β-TCP particles can be filled to enrich bone marrow mesenchymal stem cells. The present invention combines a grid scaffold prepared by titanium or zinc-based metal and its internal support column to prepare a bone tissue engineering scaffold with excellent mechanical properties, wherein the porous zinc-based metal ball can promote osteogenic differentiation and inhibit osteoclast differentiation, while providing support, promote the regeneration and ingrowth of bone tissue, and then gradually be replaced by bone tissue during the degradation process, and β-TCP particles can enrich mesenchymal stem cells and promote bone repair. The present invention can be applied to large bone defects in load-bearing parts, promote bone tissue regeneration on the basis of mechanical support, and achieve the therapeutic effect of repairing large bone defects.

The present application relates to the technical field of orthopedic implants, and in particular to an extramedullary axially pressurized and fixed femoral prosthesis, the technical solution of which mainly comprises a medullary cavity handle and a defective segment, wherein a temporary pressurizing rod is arranged at one end of the medullary cavity handle away from the defective segment; a first fixing member is arranged on the medullary cavity handle for locking the medullary cavity handle after the medullary cavity handle is pressurized; when the femoral prosthesis is replaced, the diseased bone is firstly removed, and then the medullary cavity handle is inserted into the medullary cavity of the retained bone located above the removed portion, until the end face of the defective segment close to the medullary cavity handle is fitted with the osteotomy surface of the retained bone, and the defective segment is connected to the retained bone, and then an upward force is applied to the temporary pressurizing rod to drive the medullary cavity handle to move upward, and finally the medullary cavity handle is locked by the first fixing member; such a design enables the end face of the defective segment close to the medullary cavity handle to apply continuous pressure to the end face of the retained bone, thereby promoting bone ingrowth and making the connection between the two more stable in the early postoperative period.

The present application relates to the technical field of cardiac pacing electrode, in particular to a telescopic cardiac pacing electrode, which comprises a pulse pacemaker and an electrode lead, the electrode lead comprises an insertion end, a connecting sleeve, a conductive core wire and an electrode end, the insertion end, the connecting sleeve and the electrode end are sequentially fixedly connected, the insertion end is insertedly matched with the pulse pacemaker, the connecting sleeve is internally provided with the conductive core wire, the two ends of the conductive core wire are respectively connected with the insertion end and the electrode end, and the pulse pacemaker generates a pulse electric signal which is transmitted to the inside of an organ through the electrode end; in the present application, the telescopic members and the fixing members are staggered in the subcutaneous section, the initial length is the shortest, the spacing of the fixing members anchored in the subcutaneous tissue is increased with the growth of the patient's trunk, the telescopic members are axially stretched, the length adjustment range covers the entire growth period from childhood to adulthood, the risk of electrode lead tightness, electrode displacement or breakage is fundamentally eliminated, and secondary surgery is avoided.

The application relates to the technical field of biomedical materials, and specifically discloses a preparation method of a double-crosslinked 3D-printed bone repair scaffold. The scaffold is made of a biphasic calcium phosphate matrix and a gelatin methacrylate hydrogel outer layer. The preparation method comprises the following steps: firstly, preparing biphasic calcium phosphate ink, and constructing a porous scaffold blank through 3D printing; then, carrying out double-crosslinking treatment of calcium chloride solution and glutaraldehyde solution in sequence to obtain a scaffold matrix with enhanced mechanical properties; then, preparing gelatin methacrylate hydrogel loaded with modified teriparatide, and compounding the gelatin methacrylate hydrogel with the scaffold matrix; and finally, obtaining the final product after blue light crosslinking and solidification. The bone repair scaffold has good biocompatibility and osteogenic activity, and can effectively promote bone defect repair. In addition, the preparation method is controllable and has good repeatability, the structure of the scaffold is accurately controlled through the 3D printing technology, and a new approach is provided for the preparation of personalized bone repair materials.

The utility model relates to the technical field of knee joint prostheses for knee joint plasty, in particular to a tibia prosthesis for knee joint plasty, which comprises a tibia plate and a connecting part, a threading hole is arranged on the tibia plate, and the tibia prosthesis is firmly bound on a tibia by a suture through the threading hole, so that the initial fixation of the tibia prosthesis is realized; the porous coating is arranged on the connecting part, the porous structure is beneficial to ingrowth of bone tissue, the bone ingrows into the interconnecting pore channel and extends and is interwoven, so that interlocking combination is formed between the bone and the tibia prosthesis, and the long-term biological fixing effect is achieved; therefore, the whole process of implanting the tibial prosthesis into the human body is reliably fixed. In addition, the tibia prosthesis can be suitable for people with different sclerotin, and the requirement for the sclerotin of a patient is low.

The invention belongs to the field of repair materials, and particularly relates to a titanium alloy jaw bone scaffold and a preparation method and application thereof. The titanium alloy jaw bone scaffold comprises a titanium alloy porous scaffold and a micro-nano surface structure formed on the surface of the titanium alloy porous scaffold. The 3D printing titanium alloy stent with the micro-nano structure is prepared by combining 3D printing and femtosecond laser, a new thought for reducing the stress shielding of the titanium alloy stent and improving the osseointegration capability of the titanium alloy stent is provided, the influence of the mechanical shielding effect is reduced by designing parameters such as the aperture shape and the aperture size of the porous structure, and meanwhile, the 3D printing titanium alloy stent with the micro-nano structure is prepared. A micro-nano surface is constructed by femtosecond laser treatment, so that the cell adhesion and osseointegration capability are improved, and a new treatment method is provided for repairing jaw defects.

The invention discloses a metal bone fracture plate with a stable bone fracture setting function, and relates to the technical field of medical apparatuses and instruments. The bone fracture plate comprises a first bone fracture plate body and a second bone fracture plate body which are symmetrically arranged, the sides, close to each other, of the first bone fracture plate body and the second bone fracture plate body are fixedly provided with an upper butt joint cylinder and a lower butt joint cylinder respectively, the upper butt joint cylinder is located at the top of the lower butt joint cylinder, and the axis of the upper butt joint cylinder and the axis of the lower butt joint cylinder are kept consistent; the sides, close to each other, of the first bone fracture plate and the second bone fracture plate are each fixedly provided with two hanging rotating sleeves. By arranging the upper butt joint cylinder and the lower butt joint cylinder, angle adjustment can be conducted on the first bone fracture plate and the second bone fracture plate firstly, then a bone fracture operation is conducted, the bone fracture plates do not need to be shaped in advance, shaping of the bone fracture plates can be completed through cooperation of the flower-shaped positioning columns, the upper butt joint cylinder and the lower butt joint cylinder, and the bone fracture effect is improved while the enough bone fracture surface is guaranteed. The preparation time before the bone setting operation is greatly shortened, and the treatment process of a patient is accelerated.

The utility model relates to a porous PEEK (Polyether Ether Ketone) prosthesis with an assembled tenon-and-mortise structure, which is used for repairing humeral shaft bone defects and is provided with medullary holes. Comprising a porous PEEK prosthesis reconstruction part composed of two mortise and tenon joint structures which are mutually inserted and locked through a tenon, prosthesis handles with medullary holes are arranged at the two ends of the porous PEEK prosthesis reconstruction part respectively, and the medullary holes of the prosthesis handles are communicated with the porous PEEK prosthesis reconstruction part. The diaphysis prosthesis is large in aperture, high in porosity and high in communication rate, is provided with medullary holes, can promote ingrowth of prosthesis handles at the far end and the near end of the prosthesis and reconstruction section bones, enables a patient to move in an early stage, reduces complications, improves the living standard of the patient, achieves simultaneous ingrowth of the inside and the outside of the bone, promotes the ingrowth of the bone and blood vessels into internal pores, and improves the survival rate of the bone. Mechanical locking can be formed between the new bone growing into the pores and the prosthesis material, so that the bone defect repair time is shortened, and long-term stability is realized. The accurate connection of the tenon-and-mortise structure is simpler and faster, and the operation time is shortened.