57results about How to "Good obedience" patented technology

The invention relates to a biological medical porous titanium material and a preparation method thereof. The preparation method, namely a method adopting powder metallurgy, is to add spherical particles of novel polymethyl methacrylate pore-forming agent to prepare a structure provided with a rough surface and three-dimensionally communicated open pores, wherein the number, the shape and the size of the pores can be controlled, namely, the porosity degree is less than 70vol. percent, the open porosity factor is more than 60 percent, the average pore diameter is less than 500 mums, the Young's modulus in compression is more than 0.3 GPa, the compressive strength is more than 40MPa, and the bending strength is more than 50MPa. The biological medical porous titanium material can be widely applied in the field of biological medical implants such as dental implants, artificial joints, spinal orthopaedic internal fixed systems, medullary internal nails and orthopaedic armor plates.

The invention relates to a flexible direct-drive type steering rack, which uses a flexible beam to enable a structure to be flexible. Left and right lateral racks easily do relative nodding movement, so as to be applicable to a triangular pit with a larger rail. The structure is flexible so that a series of suspension can be simplified to a very thin layer of rubber cushion, and the production cost is reduced; an elasticity transmission device is elastically suspended through a permanent magnet motor, so that the torque can be transmitted, the transmission efficiency can be improved, and the weight of a transmission mechanism can be reduced; a traction force and a braking force can be directly transmitted to a car body instead of the structure of the steering rack, and the stress condition of the structure of the steering rack is optimized; meanwhile, the length of a traction rod is not limited by the structure, so that the traction rod can be longer, the secondary addition rigidity brought by the traction rod can be reduced, and the riding comfort degree of a vehicle can be improved. A motor is suspended between wheel pairs, so that a shaft distance can be reduced. Therefore, the steering rack not only can have higher critical speed through a smaller curve, but also has good submissiveness on route irregularity.

The invention relates to a novel method for preparing menstrual blood mesenchymal stem cells. The method comprises the following steps: a, collecting menstrual blood in vitro, and storing in menstrual blood collecting liquid to obtain menstrual blood mixed liquid; b, separating single karyocyte from the menstrual blood mixed liquid; C, culturing the single karyocyte in an adherent manner, proliferating cells, and then through adherent purification, obtaining purified cells, namely the menstrual blood mesenchymal stem cells. The novel method has the advantages of being nondestructive in the body, strong in uniformity and high in cell activity which is reflected in the characteristics of high cell proliferation speed, high passage times and the like.

The invention discloses a preparation method and a use method of biologically degradable shape memory tubular support stent, wherein the steps of the preparation method comprises physical blending technology, in which the vitrification point of at least one component is below 37 DEG C and that of at least one component is beyond 37 DEG C, or chemical copolymerizing technology, in which two monomers are chemically polymerized to form degradable shape memory high polymer material composed of chain segment 1 and chain segment 2; the vitrification point of the chain segment 1 is below 37 DEG C; and the vitrification point of the chain segment 2 is beyond 37 DEG C; according to FOX formulation, the mass ratio of each polymer in physical blending technology is calculated, and the mass ratio of two monomers in chemical blending technology is also calculated, thereby ensuring that the prepared stent can recover to memorized shape at 37 DEG C of body temperature; therefore, the stent can recover to memorized shape naturally without external heating if the stent is implanted into human body; the stent is featured with convenient operation, high compliance of patients, easy preparation, no toxic matter introduced, high biocompatibility and safety.

The invention relates to a self-heating medical ultrasonic coupling agent device with sterilization and disinfection effects and a preparation method thereof. The medical ultrasonic coupling agent device comprises an outer shell. The inside of the outer shell is provided with a coupling agent cavity and a self-heating cavity which are not communicated with each other. The self-heating cavity is filled with a disposable self-heating agent. The coupling agent cavity is filled with a medical ultrasonic coupling agent with sterilization and disinfection effects. The medical ultrasonic coupling agent device utilizes the automatic heating effect of the self-heating agent to perform conduction heating on the medical ultrasonic coupling agent to make the temperature of the medical ultrasonic coupling agent reach about the temperature of the human body surface so that the patient never feels the cold stimulation of the coupling agent when being subjected to the B-ultrasound examination. Moreover, the medical coupling agent has the rapid and efficient sterilization and disinfection effects, guarantees to effectively disinfect an ultrasonic probe and prevent the cross infection in the hospital, has the retention sterilization effect on the skin or the mucosa of the examined region, has simple preparation process and saves investment and cost.

The invention discloses resveratrol micelle eye drops. The resveratrol micelle eye drops are prepared from resveratrol which serves as a main drug, a preservative and an isoosmotic adjusting agent. The resveratrol micelle eye drops are characterized by being further prepared from a polyethylene caprolactam-polyvinyl acetate-polyethylene glycol copolymer which serves as a pharmaceutical necessity, dequalinium which serves as a mitochondrion target modifier and a stabilizer, wherein the mass ratio of the main drug of the resveratrol to the pharmaceutical necessity of the polyethylene caprolactam-polyvinyl acetate-polyethylene glycol copolymer ranges from 1:20 to 1:24, and the mass ratio of the dequalinium to the pharmaceutical necessity of the polyethylene caprolactam-polyvinyl acetate-polyethylene glycol copolymer ranges from 1:40 to 1:45. According to the resveratrol micelle eye drops, the administration concentration can reach 5 mg/ml, the micelle particle size is small, the distribution range is uniform, and the drug stability is good; the administration irritation is reduced, absorption of corneas on the drug is improved, the administration concentration is reduced, the drug acting time is prolonged, the administration times are decreased, the patient compliance is improved, and the good economical efficiency is achieved.

A preparation method of hollow fiber multihole biologic titanium material belongs to biotechnology field. The invention includes steps: (1) wrapping titanium or titanium alloy fiber on a compact core rod, shaping; (2) putting the core rod wrapped with titanium or titanium alloy fiber in a mould, compacting by a hollow pressure head having inner diameter equal to diameter of the compact core rod, keeping load under load pressure, removing the mould and the core rod to get hollow multihole rods or columns with required length and porosity; (3) putting multihole titanium rods or columns compacted as body, sintering in vacuum or argon atmosphere to get hollow fiber multihole biologic titanium material. The method of this invention is simple, can get slim hollow fiber multihole biologic titanium material having optional ratio of length and diameter, fibre distribute uniformly, surface is flatten via shaping; good controllability of central cavity size, aperture and porosity, simple preparation method, fast speed, high rate of finished products, low cost.

The invention discloses a medical purpose of an NMDA acceptor antagonist and a pharmaceutical composition thereof. The invention concretely discloses a medicine for using the NMDA acceptor antagonist, a pharmaceutically acceptable salt or a pharmaceutical composition thereof for treating or preventing central nervous system disease and/or mental diseases, and the NMDA acceptor antagonist is delivered to a human central nervous system through target administration. An application of the pharmaceutical composition can increase the concentration of the NMDA acceptor antagonist in brain tissue, medicine amount is greatly reduced, and systematic side effect is reduced; biology availability in the brain is high, autonomous drug administration can be carried out by patients, no pain is generated, usage is convenient, and thus the pharmaceutical composition has good patient compliance, and has wide clinical medical science application.

The invention provides a method and a system for detecting COVID-2019 pneumonia, which belongs to the technical field of biomedicine and data processing. Expiratory NO concentration detection is carried out on a non-new coronal pneumonia patient, statistics of basic human body characteristic information is carried out, a mathematical model between the expiratory NO concentration and the basic characteristics of the human body is established, expiratory NO data of the suspected new coronal pneumonia patient are analyzed by using the mathematical model, whether a subject is sick or not is thus judged, the problem of discomfort of a human body caused by traditional nucleic acid detection sampling is effectively solved, and the method has the advantages of low cost, rapidness, no damage and the like, causes no pain to the subject, is good in compliance, is particularly suitable for being applied to large-scale preliminary screening work of suspected COVID-19 patients, and has good practical application value.

The invention relates to an aerosol for treating bedsore and a preparation method of the aerosol, and belongs to the technical field of a medical aerosol. The aerosol consists of the following components: antibacterial peptide, water-soluble chitosan, a synergist, a stabilizer, a propellant and the balance of purified water. The preparation method comprises the following steps: respectively preparing an antibacterial peptide solution and a chitosan solution, sequentially adding equivalent synergist and stabilizer to the two solutions, and then uniformly mixing the two solutions to obtain a medicine liquid, filling and sealing the medicine liquid, injecting the propellant and pressing an aerosol cover so as to obtain a finished product. Through a synergistic effect generated from the combination of the antibacterial peptide and the water-soluble chitosan, the aerosol disclosed by the invention is not only strong in antibacterial and anti-inflammatory properties, but also capable of accelerating and promoting the healing of a wound surface and quite excellent in effect of clinically treating bedsore; by virtue of the sprayed chitosan solution, a film can be rapidly formed on the surface of skin so as to effectively protect the wound surface and reduce inflection risk; and the film is degradable and absorbable, and is safe, clean and convenient; and the aerosol is stable in active ingredient, long in drug action time, free from frequent administration and good in compliance.

The invention discloses a limonene medicinal drop pill for treating biliary tract diseases, wherein the existing dosage types for the conventional limonene preparations are modified to obtain drop pills with the advantages of simple process for manufacturing, shorter disintegration time, quicker action, better pharmaceutical stability, and longer effective period.

The invention relates to traditional Chinese medicine powder for treating skin pruritus and application thereof. The traditional Chinese medicine powder comprises, by weight, 30-60 parts of stove ash, 10-30 parts of radix sophorae flavescentis, 10-30 parts of fructus cnidii, 10-30 parts of radix stemonae, 2-5 parts of borneol, 2-5 parts of menthol and 5-10 parts of borax. The traditional Chinese medicine powder is suitable for being used to treat eczema, beriberi, tinea cruris, scrotal eczema and pruritus vulvae. The traditional Chinese medicine powder has effects of improving the microenvironments of the affected parts of a patient and inhibiting bacteria and is capable of promoting the recovery of skin functions, good in curative effect and high in cure rate.