332 results about "Menstrual blood" patented technology

An elongated absorbent article including: an absorbent article body having at least: (a) a top sheet part which is at least partially liquid permeable and arranged on a first side in a thickness direction of the absorbent article; and (b) a liquid retainable absorber part arranged on a second side in the thickness direction of the absorbent article body; a cover member arranged on the second side in the thickness direction of the absorbent article body; an extensible belt-shaped member disposed between the absorbent article body and the cover member, a first end portion of the belt-shaped member being connected to the absorbent article body; an engaging part arranged at a second end portion of the belt-shaped member on a surface thereof on which the cover member is disposed; a peelable sheet arranged along a surface of the engaging part; and a fixing part for connecting and fixing the peelable sheet to the cover member; the fixing part being formed so that an end portion thereof in a direction of elongation of the belt-shaped member is arranged at either one of a position corresponding to an end portion of the engaging part in the direction of elongation, and a position more towards the direction of elongation. This improves the adhesion between the wearer's excretory part and the absorbent article, thereby preventing the leakage of excrement such as menstrual blood.

The present invention relates an interlabial pad to be fitted to the labia providing an interlabial pad with flap portions that can maintain the retention state in the interlabial space irrespective of the quantity of body fluid discharge such as menstrual blood. A mini-sheet piece (3) is attached to the opposite side face to the body side face (2b) of the interlabial pad (2) in such a way that a part of it protrudes from both side edges of the interlabial pad (2) forming flap portions (4A) and (4B). Adhesives (6A) and (6B) are applied to the body side face of the flap portions (4A) and (4B). The interlabial pad (2) is retained in the interlabial space and the flap portions (4A) and (4B) are affixed to the surface of the labia majora to fit the interlabial pad with the flap portions (1).

A sanitary napkin has a top layer, an absorbent layer and a bottom layer with a sensor layer. The absorbent layer has a hollow portion covered with a silk-made cover layer and has multiple holes defined in the cover layer, wherein some silk cloth filled inside the hollow portion. By having the hollow portion with silk cloth, the menstrual blood is drained quickly and absorbed by the absorbent layer to keep the sanitary napkin dry at the top layer and to avoid toxic vapor. Moreover, the holes on the cover layer provide a ventilating efficiency and the silk is cool to be contact so that muggy feeling is efficiently reduced. The sensor at the bottom layer conveniently indicates the changing occasion to the user.

A hemispherical receptacle made of compressible material for menstrual fluid collection is disclosed herein. In a preferred method the receptacle is compressed during insertion. The receptacle further has a resilience for restoring to its original shape after being inserted into the vagina. To facilitate removal, the receptacle includes a pulling ring at a lower end thereof; and a unique flange lid portion is included at an open upper end acting as a funnel to direct the menstrual blood into the receptacle. This unique flange portion is designed with a living hinge that transfers the device from a closed to an open position. In the closed position, the flange portion allows blood to get into the receptacle while preventing it from spilling out. The open position herein is for emptying and cleaning the receptacle.

The present invention relates to an interlabial pad which is attached between female labia, especially to the pad which can be used together with the sanitary napkin, which has a good sealing efficiency with the labia deepest portion when the user moves and can prevent the chance that the leak of the menstrual blood or the dropping off of the pad is occurred. Further the interlabial pad comprises the absorbing sheet portion facing to the body side upon wearing the pad and the support sheet portion backing the absorbing sheet portion. The absorbing sheet portion includes the absorbent body (13a) which is a stick-shaped or a strip-shaped individual absorbent body and contacts with the neighborhood of the ostium vaginae of the user, the absorbent body (13b) which is a flat-shaped individual absorbent body and contacts with at least of the inner wall of the labia of the user, further said absorbent body for contacting ostium vaginae(13a) is disposed along the substantial center line of the body face side of absorbent body for contacting the inner wall of the labia (13b).

A hemispherical receptacle made of compressible material for menstrual fluid collection is disclosed herein. In a preferred method the receptacle is compressed during insertion. The receptacle further has a resilience for restoring to its original shape after being inserted into the vagina. To facilitate removal, the receptacle includes a pulling ring at a lower end thereof; and a unique flange lid portion is included at an open upper end acting as a funnel to direct the menstrual blood into the receptacle. This unique flange portion is designed with a living hinge that transfers the device from a closed to an open position. In the closed position, the flange portion allows blood to get into the receptacle while preventing it from spilling out. The open position herein is for emptying and cleaning the receptacle.

A topsheet for absorbent articles having absorbing performance for smoothly transferring liquid body waste, e.g., menstrual blood or urine, to an underlying absorbent member and surface characteristics such that the surface thereof in contact with wearer's skin is soft enough not to cause skin irritation. The topsheet 1 comprises a first layer 11 disposed on the side of a wearer and a second layer 12 disposed on the side of an absorbent member, the first layer and the second layer being partly joined together, and having protrusions and depressions on the side of a wearer, wherein the first and second layers each comprise a fiber aggregate, the first layer has fusion-bonded fiber intersections, the first layer has an apparent thickness (t1) of 0.1 to 5 mm, the second layer has an apparent thickness (t2) of 0.2 to 3 mm, the apparent thickness ratio of the first layer to the second layer (t1 / t2) is 0.5 to 8, the first layer has a fiber density (d1) of 0.001 to 0.05 g / cm3, the second layer has a fiber density (d2) of 0.03 to 0.2 g / cm3, and the fiber density (d2) of the second layer is higher than that (d1) of the first layer.

A pad has an absorbing part. The absorbing part has a longitudinal groove and a guiding layer. The longitudinal groove is defined in middle of the pad. The guiding layer is mounted in the longitudinal groove and has a body and a line. The body is mounted in the longitudinal groove and has an upper end. The line connects with the upper end of the body. The line has two ends. The ends are held by user to pull up, so user can adjust the guiding layer to level at the crack between buttocks and absorb the menstrual blood from vagina immediately. Thus, user can sleep well, exercise freely and do not worry that the menstrual blood will flow out the pad to dirt the knickers or a bed sheet.

A sanitary napkin includes a napkin body containing a liquid absorbent layer and a three-dimensional structure is disposed on the skin-side surface of the napkin body. The three-dimensional structure is formed of an air-laid nonwoven fabric and a liquid-permeable sheet, and the air-laid nonwoven fabric is formed with upwardly extending compressed portions. The three-dimensional structure comes into close contact with the body's groove to effectively prevent lateral leakage of menstrual blood during sleep.

A sanitary napkin includes a napkin body containing a liquid absorbent layer and a three-dimensional structure is disposed on the skin-side surface of the napkin body. The three-dimensional structure is formed of an air-laid nonwoven fabric and a liquid-permeable sheet, and the air-laid nonwoven fabric is formed with upwardly extending compressed portions. The three-dimensional structure comes into close contact with the body's groove to effectively prevent lateral leakage of menstrual blood during sleep.

A topsheet for absorbent articles having absorbing performance for smoothly transferring liquid body waste, e.g., menstrual blood or urine, to an underlying absorbent member and surface characteristics such that the surface thereof in contact with wearer's skin is soft enough not to cause skin irritation. The topsheet 1 comprises a first layer 11 disposed on the side of a wearer and a second layer 12 disposed on the side of an absorbent member, the first layer and the second layer being partly joined together, and having protrusions and depressions on the side of a wearer, wherein the first and second layers each comprise a fiber aggregate, the first layer has fusion-bonded fiber intersections, the first layer has an apparent thickness (t1) of 0.1 to 5 mm, the second layer has an apparent thickness (t2) of 0.2 to 3 mm, the apparent thickness ratio of the first layer to the second layer (t1 / t2) is 0.5 to 8, the first layer has a fiber density (d1) of 0.001 to 0.05 g / cm<3>, the second layer has a fiber density (d2) of 0.03 to 0.2 g / cm<3>, and the fiber density (d2) of the second layer is higher than that (d1) of the first layer.

The invention provides an application of exosome to preparing of acute-hepatic-failure treating medicine. The exosome is an exosome secreted through personal-menstrual-blood mesenchymal stem cells. The invention further provides a medicine composition, wherein the medicine composition comprises the exosome secreted through the personal-menstrual-blood mesenchymal stem cells and carriers acceptable in pharmacy. According to the medicine composition in the technical scheme, the survival time of an acute-hepatic-failure animal model can be prolonged, the bleeding rate and the necrotic rate of the livers can be decreased, and secreting of inflammatory factors through liver cells can be promoted, so that acute hepatic failure is effectively treated, and prognosis of an acute-hepatic-failure patient is improved accordingly.

An absorbent article which can effectively widen absorbing area of excretion liquid at a center portion of the absorbent article, is provided. Divided absorbent elements are formed dividingly on both of a center line. The divided absorbent elements are fixed on a back sheet at positions of compressed portions, and inner side end portions of the divided absorbent elements are taken as free ends. Upon use of a sanitary napkin, by bending the sanitary napkin in response to exertion of compressing force F from femoral parts, the divided absorbent elements are raised so that menstrual blood can be absorbed not only through inner surfaces but also through outer surfaces. Therefore, absorbing area can be greater than that of the conventional sanitary napkin, and side leakage can be successfully prevented.

The invention provides a method for preparing mesenchymal stem cells of menstrual blood. The method comprises steps as follows: female menstrual blood is collected and taken as a raw material and is subjected to sterile processing; stem cells in the menstrual blood are separated; the mesenchymal stem cells of the menstrual blood are cultured; the mesenchymal stem cells of the menstrual blood are cryopreserved; and the mesenchymal stem cells of the menstrual blood are recovered. The method has the technical characteristics as follows: the female menstrual blood is collected and stored in a preservative fluid; by means of a bacterial pollution prevention method, the pollution probability is reduced from a collection source, a collecting cup is repeatedly washed by sterile water, and the pollution probability is effectively reduced; with the adoption of a differential centrifugation method, bacteria in the menstrual blood are removed as far as possible; a sample is repeatedly separated by HES (hydroxyethyl starch), and the maximum quantity of mesenchymal stem cells of the menstrual blood can be obtained; a serum-free medium is utilized for culturing, components of animal origin are reduced, the cell performance is stable, the in-vitro long-term culturing process of the mesenchymal stem cells of the menstrual blood can be kept, and cellular morphology, multiplication capacity, MSC (mesenchymal stem cell) surface marker expression, differentiation capacity and the like are maintained. The method is simple, practical and convenient to operate, the maximum quantity of required stem cells can be obtained, and the stem cells are successfully cultured.

The present invention relates to an interlabial pad which is attached between female labia, especially to the pad which can be used together with the sanitary napkin, further to a wrapping body where said interlabial pad is contained individually in a wrapping container, and the present invention provides an interlabial pad in capable of rapidly directing the menstrual blood which flows down along the inner wall of labia to an absorbent body and in capable of improving the shape fitness (fitness ability) within labia. The interlabial pad (14) comprises the absorbing sheet and the support sheet (12) backing the absorbing sheet. The absorbing sheet is formed as an aggregate juxtaposing a plurality of strip-type absorbing areas, the absorbing area includes an absorbent body (13a, 13b) which is individually contained in a cover sheet (11a, 11b), and the strip-type absorbing area is formed into an area (14a) contacting with the neighborhood of the ostium vaginae of the user and an area (14b) contacting with an inner wall of labia of the user.

The invention provides a novel menstrual blood-derived mesenchymal stem cell separation method, belonging to the field of methods for separating stem cells from menstrual blood. In order to solve the problems of long centrifugal time, relatively serious cell injury, low cell yield and the like existing in a lymph separating medium method in the traditional method, the invention provides the novel menstrual blood-derived mesenchymal stem cell separation method comprising the steps of with source-wide menstrual blood as a material, storing by using a special preserving fluid in a collecting process; then, carrying out primary separation by using a density gradient centrifugation method of a lymphocyte separation tube, and optimizing the centrifugal time and centrifugal rotating speed in separation; and next, carrying out secondary separation according to the wall attachment growth characteristic of the stem cells, simultaneously separating and amplifying the stem cells, and maintaining the activity of the stem cells to the maximum extent in the separation process. The obtained menstrual blood-derived mesenchymal stem cell is high in purity, quantity and application value. The novel menstrual blood-derived mesenchymal stem cell separation method is simple in operation and low in cost.

The invention provides a stem cell preparation for treating hepatic fibrosis, and a preparation method of the stem cell preparation. The stem cell preparation for treating hepatic fibrosis is prepared from human menstrual blood mesenchymal stem cells, a chemotactic factor CXCL8 and normal saline. The obtaining method of the menstrual blood mesenchymal stem cells is simple, free of ethical restriction, high in cell viability and high in proliferation capacity, has multi-directional differentiation potential and is simple and convenient to prepare. The menstrual blood mesenchymal stem cell preparation infusion technology provided by the invention is simple and convenient to operate; the hepatic fibrosis is treated by virtue of the menstrual blood mesenchymal stem cells; and the developed preparation method of the stem cell preparation for treating the hepatic fibrosis has very important clinical significance and wide application prospect.

The invention provides a stem cell culture medium and a method for culturing endometrium stem cells by using the stem cell culture medium. The method comprises the following steps: separately collecting menstrual blood and endometrium tissues, respectively culturing the menstrual blood and endometrium tissues in the stem cell culture medium provided by the invention to respectively obtain menstrual blood adherent cells and endometrium adherent cells, culturing the menstrual blood adherent cells and endometrium adherent cells in a cell culture bottle, collecting the adherent cells by trypsinization, inoculating the adherent cells in a cell coculture dish, and culturing the adherent cells in the stem cell culture medium provided by the invention. The stem cell culture medium has the advantages of simple components, fewer added components and lower cost. After more than 20 generations of in-vitro culture, the cells can not easily have the phenomenon of aging or degeneration, and can maintain the activity and stem property of the stem cells for a long time. The stem cell culture method is simple and effective, the cell proliferation efficiency is high, and the in-vitro culture doubling time is only 20 hours or so. The cells can be stably amplified by 50 generations.

Disclosed is a sanitary napkin which is allowed to quickly absorb menstrual blood and also effective in preventing absorbed menstrual blood from returning to the skin-side surface under pressure and in concealing the color of absorbed menstrual blood from the outside. Between a liquid absorbent layer and a topsheet formed of a resin film having a large number of liquid passage apertures, there is disposed a barrier layer formed of a resin film having a large number of liquid passage apertures. The barrier layer is composed of a plurality of strip-shaped elements, and liquid passage regions are defined between adjacent elements of the barrier layer. After passing through the liquid passage apertures of the topsheet, menstrual blood tends to be absorbed by the liquid absorbent layer through the liquid passage regions. The barrier layer functions to prevent liquid return and conceal the color of menstrual blood.

A pad has a rear end and an absorbing part. The absorbing part has an absorbing belt. The absorbing belt is mounted on the absorbing part and has a distal end. The distal end of the absorbing belt extends and protrudes from the rear end of the pad. Users can hold the distal end of the absorbing belt and adjust the absorbing belt to level at a crack between buttocks. Thus, menstrual blood flowing along the crack between buttocks will be absorbed by the absorbing belt and then flow along the absorbing belt to the absorbing part of the pad. Therefore, users do not worry that menstrual blood will flow out of the pad at night to dirt knickers and a bed sheet.

An interlabial pad, which is fitted between labia and absorbs menstrual blood and other body fluids, and a surface side sheet used in this interlabial pad are presented. The surface side sheet is used in the interlabial pad that is fitted between labia and has a fiber aggregate having a wet shear strength with respect to labial inner walls of no less than 15 cN / 25 mm and no more than 60 cN / 25 mm when containing an artificial menstrual blood at a content of 800%. The artificial menstrual blood being a fluid composition includes water, glycerin, sodium carboxymethylcellulose, sodium chloride, sodium bicarbonate, and a food dye preparation. Even when the shape of the labia changes because of movement of a wearer in a highly wet state after absorption of menstrual blood, since the shear force that arises between the labial inner walls and the interlabial pad can be resisted, positional deviation and falling off of the interlabial pad can be prevented. The interlabial pad can thus be fitted securely between the labia even without using an adhesive agent.

The invention provides a method of preparing endometrium mesenchymal stem cells from menstrual blood. The method comprises the steps that firstly, a menstruation tampon is placed in the vagina of a woman during the menstrual period of the woman, wherein the menstruation tampon comprises an absorption tampon body which is provided with a water absorption fiber core, the water absorption fiber core is wrappedina gauze absorption layer, and the menstruation tampon is kept in the vagina till menstrual blood and / or deciduous endometrial tissue are adsorbed on the gauze absorption layer; secondly, a pull wire is pulled out to take out the menstruation tampon, the menstrual blood and / or the deciduous endometrial tissue adsorbed on the gauze absorption layer are eluted off with eluant to obtain an eluted product; thirdly, karyocytes are extracted from the eluted product and subjected to cell culture. The method can be conveniently used clinically and can be accepted by menstrual blood donators; moreover, the obtained endometrium mesenchymal stem cells have higher proliferative activity.

Disclosed is a sanitary napkin containing polymeric absorbents and herbal ingredients, and more particularly to a functional sanitary napkin, in which a absorbent layer structure having the polymeric absorbents and herbal ingredients distributed thereon consists of three layers of non-woven fabric (or pulp) and is surrounded by a polymeric absorbent—containing surge layer made of an air-laid material, such that the ability to absorb menstrual blood is increased and the odor of the herbal ingredients is prevented from permeating undergarments, garments, bags and the like.

The invention relates to a novel method for preparing menstrual blood mesenchymal stem cells. The method comprises the following steps: a, collecting menstrual blood in vitro, and storing in menstrual blood collecting liquid to obtain menstrual blood mixed liquid; b, separating single karyocyte from the menstrual blood mixed liquid; C, culturing the single karyocyte in an adherent manner, proliferating cells, and then through adherent purification, obtaining purified cells, namely the menstrual blood mesenchymal stem cells. The novel method has the advantages of being nondestructive in the body, strong in uniformity and high in cell activity which is reflected in the characteristics of high cell proliferation speed, high passage times and the like.

Method and apparatus are disclosed for applying a therapeutic amount of a non-systemic vasoconstrictor inside the uterus to control abnormal uterine bleeding. The abnormal bleeding can be due to excessive menstrual blood flow, bleeding from a surgical procedure, postpartum bleeding or any other acute or chronic condition. The vasoconstrictor includes topical agents such as an alpha-adrenergic agonist, for example oxymetazoline. The delivery system can include a catheter having means for retaining position of a distal portion within the uterus. A proximal portion can extend outside of the body for coupling to a vasoconstrictor source, or alternatively, the proximal portion can terminate within the vaginal canal and include a docking port for coupling to a source of vasoconstrictor that is inserted therein. In other embodiments, an applicator is disclosed that is positioned in fluid communication with the lumen of the cervix and allows application of a vasoconstrictor therein.

The invention provides a method for establishing a uterine membrane stem cell bank. The method comprises the steps of menstrual blood collection, uterine membrane stem cell separation and degerming, amplification, analysis, detection, long-term storage and regular detection. The invention provides a degerming method which is simple and easy to operate. The method provided by the invention can obtain a large quantity of higher-purity uterine membrane stem cells by carrying out amplification culture on the uterine membrane stem cells with substances (such as bacteria) removed and can be used for storing the uterine membrane stem cells for a long time, thereby providing a large quantity of uterine membrane stem cell resources for future clinical and scientific research application study.

The invention relates to a bacteriostatic odor-removing absorption article and a manufacturing method thereof. The bacteriostatic odor-removing absorption article sequentially comprises a non-woven fabric surface layer, an absorption layer and a bottom film layer from top to bottom; the absorption layer comprises an upper absorption layer and a lower absorption layer, the upper absorption layer is composed of at least one super absorbent resin absorbent paper layer, and the lower absorption layer is a bacteriostatic odor-removing absorption layer; and the bacteriostatic odor-removing absorbing layer contains a bacteriostatic odor-removing absorbing material, the bacteriostatic odor-removing absorbing material is formed by mixing a bacteriostatic odor-removing material and super absorbent resin, and the bacteriostatic odor-removing material is composed of cortex phellodendri chinense, wormwood, golden larch bark, fructus cnidii, honeysuckle and herba leonuri. The bacteriostatic odor-removing absorption article has good bacteriostatic, odor-removing and menstruation-regulating effects, and has the characteristics of instant absorption (rapid absorption of liquid such as menstrual blood or urine), instant drying, effective locking of liquid such as menstrual blood or urine, low reverse osmosis, good dryness, comfort, close fitting and the like.