3D-printed gradient-diameter medical porous metal bone tissue scaffold

Abstract

The invention discloses a 3D-printed gradient-diameter medical porous metal bone tissue scaffold and aims to solve the problems that a single repeated microporous structure in the prior art is adverse to bone tissue ingrowth and a bone tissue implant has difficulty in bony healing with self-bones. The scaffold is in a hexahedron structure as a whole, and comprises components A, components B and components C in tight arrangement, wherein the components A are arrayed on an outermost layer of the hexahedron structure; the components B are arrayed on a secondary outer layer; and the components C are arrayed on the innermost layer; all the components A, B and C are in a hexahedron frame structure; the pore diameter of the components A is greater than that of the components B; and the pore diameter of the components B is greater than that of the components C. Through the reinforcing structural design, the gradient-pore tissue engineering bone scaffold is produced; through regulating the ingrowth of bone tissues, fibroblasts and the like by gradient-change pores, the optimal bone healing can be achieved finally.

Description

technical field [0001] The invention relates to a 3D printing medical metal implant, in particular to a 3D printing gradient aperture medical porous metal bone tissue support, which is beneficial to the growth of bone tissue and promotes bone healing. Background technique [0002] The preparation of porous metal by 3D printing is of great significance for the development of tissue engineered bone, which reduces the damage to the patient's body caused by autologous bone transplantation, and also avoids the high cost of allogeneic bone transplantation. Swedish Arcam has successfully prepared orthopedic implants such as metal alloy acetabular cups, femoral stems, spine and skull through 3D printing technology, and some porous metal alloy bone repair implants have been used clinically. [0003] Porous metal printing mainly adopts the porous metal manufactured by electron beam melting (EBM) 3D printing technology, such as the Swedish Arcam company. The micropore size, porosity, c...

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the problem that the single repeating microporous structure in the prior art is not conducive to the growth of bone tissue, and it is difficult for the bone tissue implant to achieve bone healing with its own bone, and to provide a 3D printing gradient aperture medical porous metal bone tissue Scaffold, strengthen the structure design, make the tissue engineering bone scaffold with gradually changing pores, regulate the ingrowth of bone tissue and fibroblasts through the gradually changing pores, and finally achieve the best bone healing

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