7 results about "Stearyl alcohol" patented technology

This invention relates to the field of nanomedicine formulation technology, and discloses a ROS-responsive astaxanthin nanoparticle, its preparation method, and its application. The preparation method includes: catalyzing the transketalization reaction of 3-mercaptopropionic acid with 2,2-dimethoxypropane using an alcohol-water tolerant Lewis acid catalyst (preferably scandium trifluoromethanesulfonate) to prepare a thioketal monomer containing dual-terminated carboxyl groups; coupling the thioketal monomer with stearyl alcohol and methoxy polyethylene glycol using a stepwise sequential coupling strategy to construct an amphiphilic polymer with thioketal bonds as ROS-responsive connecting units; co-dissolving the polymer, astaxanthin, and tocotrienols in tetrahydrofuran, and preparing the nanoparticles using a multi-inlet micro-collision flow nanoprecipitation process. The resulting nanoparticles have a particle size of 100 nm to 200 nm, an astaxanthin encapsulation rate of 90% to 99%, and achieve targeted release in response to reactive oxygen species in the pathological microenvironment. Astaxanthin and tocotrienols synergistically exert antioxidant effects.

The present application relates to the technical field of asiatic acid, and particularly relates to an asiatic acid derivative and a preparation method. The asiatic acid derivative provided by the present application has R which is an alkyl group formed by removing a hydroxyl group from a saturated or unsaturated monohydric alcohol, and the saturated or unsaturated monohydric alcohol includes one of ethanol, octanol, hexadecanol, stearyl alcohol, 2-hexyl-1-decanol, decyltetradecin, oleyl alcohol, cis,cis-9,12-octadecadienol and bisabolol. The asiatic acid derivative of the present application has higher water solubility and oil solubility, especially oil solubility, so that the asiatic acid derivative has obviously enhanced liposolubility, is easily soluble in natural oil, alkane and other ester solvents, and has a significant inhibitory effect on EDNRA and TRPV1 and obviously enhanced bioactivity. The asiatic acid derivative of the present application has high availability, and the asiatic acid derivative has no safety risk.

FIELD: cosmetics.SUBSTANCE: cosmetic composition in the form of a cream-gel for skin cleansing contains purified water; an emulsifier consisting of cetyl alcohol, glyceryl stearate, PEG-75 stearate, ceteth-20 and steareth-20; glycerin; coco-glucoside; a co-surfactant consisting of purified water, glyceryl oleate and coco-glucoside; cetearyl alcohol; caprylic / capric triglyceride; panthenol; butylene glycol; squalane; oat extract; sodium acrylate / sodium acryloyldimethyl taurate copolymer; cocamidopropyl betaine; cholesterol; ceramide complex including: ceramides NP, AP, AS, NG, glycosphingolipids, hydrogenated lecithin and auxiliary components; fructooligosaccharides; hydroxyacetophenone; preservative consisting of 1,2-hexanediol and caprylyl glycol; tocopheryl acetate; fragrance; arginine and disodium EDTA, in a certain ratio of components, wt.%.EFFECT: relisble removal of impurities from the skin's surface, restoration of the damaged protective barrier of the skin during washing without causing excessive dryness of the skin, relief of irritation and moisturization of the skin.1 cl, 3 tbl, 4 ex

This invention discloses a method for preparing temperature-sensitive cooling, whitening, and sun-protective microspheres, relating to the field of cosmetic technology. The sun-protective microspheres are made from the following raw materials in parts by weight: stearic acid 1-3 parts, cetyl alcohol 1-3 parts, lauric acid 1-3 parts, stearyl alcohol polyether 2 1-2 parts, stearyl alcohol polyether 21 1-2 parts, cyclopentamethoxysiloxane 1-2 parts, cetearyl alcohol 2-4 parts, polydimethylsiloxane 1-2 parts, vitamin E 0.4-0.6 parts, deionized water 75-95 parts, niacinamide 1-3 parts, liquid paraffin 3-6 parts, Span 80 0.2-0.8 parts, titanium dioxide 4-7 parts, and citric acid solution 0.1-0.2 parts. This invention provides a method for preparing temperature-sensitive cooling, whitening, and sun-protective microspheres. By utilizing temperature-sensitive microsphere encapsulation and temperature-stimulation response technology, it can effectively solve the problems of poor cooling effect, low utilization rate of active sunscreen ingredients, and heavy and sticky feel of traditional sunscreen products. Furthermore, it allows the sunscreen active ingredients to be precisely released and exert their effects when the human skin temperature rises. This not only improves sun protection efficiency but also has a skin cooling function and improves the skin feel.

The application discloses a kind of silane crosslinking polyethylene pipe with light oxygen aging resistance of double-layer structure and preparation method thereof, belong to silane crosslinking polyethylene pipe field.The silane crosslinking polyethylene pipe of the application is designed as double-layer structure, by optimizing the composition of outer layer, so as to achieve the purpose of light oxygen aging resistance, wherein, compound tetra [beta- (3,5-di-tert-butyl-4-hydroxyphenyl) propionic acid] pentaerythritol ester, tris (2,4-di-tert-butylphenyl) phosphite, thiodipropionic acid distearyl ester are used as main antioxidant, and auxiliary antioxidant is added as quercetin stearate, synergistic antioxidant effect is improved, antioxidant performance and thermal oxygen stability are improved, self-made ultraviolet absorber is also added, with large molecular weight, can be firmly anchored in polyethylene matrix, reduce migration and volatilization, and then play more excellent ultraviolet resistance effect, and main antioxidant, auxiliary antioxidant and light stabilizer synergistic effect, reach the effect of significant light oxygen aging resistance.

This invention discloses a compound Bletilla striata frostbite ointment. The ointment is composed of traditional Chinese medicine ingredients and an ointment matrix. The traditional Chinese medicine ingredients include Bletilla striata, raw Angelica sinensis, raw Cinnamomum cassia, Paeonia lactiflora, Asarum sieboldii, Tetrapanax papyriferus, chili pepper twigs, eggplant twigs, Ilex chinensis twigs, fresh watermelon rind, and fresh banana peel. The ointment matrix comprises an oil phase consisting of stearic acid, stearyl alcohol, petrolatum, and liquid paraffin; a Tween 80 emulsifier; and an aqueous phase consisting of glycerin and distilled water. The preparation method includes: decocting some of the medicinal materials into a clear ointment, and pulverizing some of the medicinal materials into a fine powder; melting and heating the ointment matrix and the clear ointment together, then sequentially adding the heat-resistant medicinal powder and the fine powder of Bletilla striata, and stirring to form an ointment. This invention has a reasonable formulation, and through the synergistic effect of the traditional Chinese medicines, it exerts the effects of warming the meridians and promoting blood circulation, removing blood stasis, and promoting wound healing and tissue regeneration. The preparation has good stability, is easy to use, and can effectively promote the healing of frostbite wounds, reduce inflammatory reactions, and lower the risk of recurrence.

The application discloses a kind of 1,2-o-phthalic acid stearyl alcohol ester-containing compositions, including 1,2-o-phthalic acid stearyl alcohol ester, chitosan adjusts bentonite modified nano zinc oxide agent, modified whisker liquid;Wherein 1,2-o-phthalic acid stearyl alcohol ester, chitosan adjusts bentonite modified nano zinc oxide agent, modified whisker liquid mass ratio is (1-2) :(5-7) :(13-15).The 1,2-o-phthalic acid stearyl alcohol ester-containing composition of the application uses 1,2-o-phthalic acid stearyl alcohol ester with chitosan adjusts bentonite modified nano zinc oxide agent, modified whisker liquid, the composition prepared in plastic product application, can effectively improve the plastic gap impact strength of plastic product, bacteriostatic durability, coordinate and improve the efficiency of product.