75 results about "Biomimetic materials" patented technology

The invention discloses a breathable plant leaf biomimetic material with antifouling, self-cleaning and spectrum simulation properties and a preparation method of the breathable plant leaf biomimetic material. The breathable plant leaf biomimetic material can be applied to a base material through a two-step coating method. The first layer is a mesophyll-like porous dual-network hydrogel structure, hyperspectral pigment and moisture absorption salt are dispersed in the first layer, spectral characteristics of plant leaves in visible light and near infrared bands are simulated, and a water transpiration function controlled by plant pores is reproduced through a pore structure and a salt medium, so that stable spectral response and dynamic water exchange are realized; and the second layer is a leaf-skin-imitated coating, and has long-term stable antifouling and self-cleaning characteristics through a liquid-like super-smooth hydrophobic surface structure. The plant leaf spectrum simulation coating has anti-mud and hydrophobic properties, can still keep an excellent plant leaf spectrum simulation effect after being washed by rainwater, and can realize high-weather-resistance spectrum simulation.

The present invention discloses a smart bio-inspired material design platform to satisfy multi-objective material design featuring complex microstructure for the future. the platform sets mechanical properties of a simulative material element via establishing a reduced model. A distribution of the simulative material element is simulated so as to output a material simulative parameter. A deep learning framework is combined in the platform for computing and evaluating an optimal material design that meets a target material parameter. Specifically, the reduced model can be based on data provided by any test of material mechanical properties, and the deep learning framework evaluates whether a biomimetic material design meets demand of the optimal target material parameter according to a standardized reward function model. The platform is applicable to multi-objective simulative material design, and is greatly potential for futuristic applications.

The invention relates to the field of biomimetic materials, in particular to a biomimetic self-cleaning anti-fouling aquaculture net cage material, a preparation method and application of the biomimetic self-cleaning anti-fouling aquaculture net cage material. 0.5 to 2.0 parts by weight of a carboxylated graphene nanosheet; 2.0 to 5.0 parts by weight of nitrogen-doped titanium dioxide nanoparticles; 1.0 to 3.0 parts by weight of silica nanoparticles; 5.0 to 10.0 parts by weight of calcium ion cross-linked modified sodium alginate; 1.0 to 3.0 parts by weight of octadecyl trichlorosilane; 0.5 to 1.5 parts by weight of lauryl sodium sulfate; through the synergistic effect of a double bionic structure and enhanced photocatalysis, the effective inhibition on attachment of various organisms is realized, and the inhibition rate on attachment organisms such as algae, bacteria and barnacles reaches 75% or above.

The invention provides a sole soft tissue physiological environment simulation and multi-modal detection system, and belongs to the technical field of human body biomechanical detection. The method solves the problem that a traditional evaluation method is difficult to comprehensively analyze biomechanical characteristics and pathological mechanisms. The plantar soft tissue physiological environment simulation and multi-mode detection system comprises a sealed detection cabin, a bionic foot and a detection system arranged in the sealed detection cabin, the detection system comprises a humidity generation module used for humidity environment simulation, a heating module used for temperature environment simulation, a humidity sensing module used for temperature monitoring, a temperature sensing module used for temperature monitoring, an ultrasonic sensing module used for data acquisition and an infrared thermal imaging module. The system has the advantages that a detection system capable of reproducing the real physiological state of the sole is constructed by accurately simulating the physiological environment of the soft tissue of the sole through environment simulation, data acquisition and multi-modal fusion analysis, and multi-dimensional data support is provided for the design of a biomimetic material.

The invention provides super-stretched liquid metal-natural rubber composite hydrogel as well as a preparation method and driving-sensing synergistic bionic application thereof, liquid metal eutectic gallium indium is crushed into nano-particles, and then the nano-particles are combined with natural rubber latex to be compounded with poly (N-isopropylacrylamide), so that the super-stretched liquid metal-natural rubber composite hydrogel is prepared. The liquid metal-natural rubber composite intelligent hydrogel driving-sensing dual-function synergistic double-layer structure biomimetic material can be obtained. The material has the super-tensile property (the tensile rate is 1300%) and has the high deformation speed (the bending speed can reach 62 degrees / s) under photo-thermal driving. As the hydrogel contains liquid metal, the hydrogel has excellent conductivity (the conductivity can reach 5532 [mu] S / cm), and an electric signal can be monitored in real time in a photoresponse bending process, so that the hydrogel has an application prospect in the field of photothermal driving-self-sensing dual-function synergistic materials.

The invention relates to the technical field of biomimetic materials, in particular to a solvent-mediated rigidity-adjustable material, a preparation method and application. The rigidity-adjustable material comprises a base material, wherein the base material comprises a hydrophobic main chain and a spatial cross-linked network structure formed by hydrophilic side chains grafted to the hydrophobic main chain in a comb shape; the base material forms a nanoscale hard domain under the triggering of a polar or non-polar solvent, and forms a polar hardened body material or a non-polar hardened body material respectively; in the hardened body material, the size of the hard domain is in positive correlation with the surface energy of the solvent, the modulus amplification of the hardened body material relative to the matrix material is directly determined by the size of the hard domain, and the modulus amplification can reach 9.9 times; and after multiple swelling-desolventizing cycles, the modulus attenuation is less than 5%. The material provided by the invention breaks through the defects that the modulus switching range of the existing material is mostly limited to be less than 5 times, and the rigidity is improved along with the obvious reduction of the toughness, and has a wide application prospect in the fields of wearable electronics, soft robots, anti-impact protection and the like.

The invention relates to a preparation method of a biomimetic material for simulating oral masticatory mucosa and a product and application thereof, the preparation method comprises the following steps: cloning a coding gene of a protein containing a VPGXG repetitive unit into an expression vector to obtain a first expression vector; cloning the coding gene of the protein containing the VPGXG repetitive unit into the expression vector, and adding cysteine to each of the two ends of the protein to obtain a second expression vector; respectively transferring the first expression vector and the second expression vector into competent cells for expression, separation and purification of proteins to obtain a first expression vector protein and a second expression vector protein; and mixing the first expression vector protein, the second expression vector protein and the multi-arm PEG-MAL solution to obtain the multi-arm PEG-MAL. The hydrogel prepared by the invention accurately simulates the characteristics of oral chewing mucosa in mechanical properties, has no cytotoxicity, can replace real oral mucosa for experiments, and can be widely applied to the experimental fields of drug release, cell culture, gas component monitoring and the like.

The application discloses a kind of photo-curing mussel biomimetic acylhydrazone and its preparation method and application, the structural formula of the photo-curing mussel biomimetic acylhydrazone is as shown in formula (I).The photo-curing mussel biomimetic acylhydrazone of the application has catechol structure and carbon-carbon double bond, raw material is low in price, synthesis process does not need to modify catechol structure, preparation method is simple, can reduce the synthesis difficulty and production cost of mussel biomimetic material.The mussel biomimetic photo-curing adhesive composition prepared by using photo-curing mussel biomimetic acylhydrazone as raw material has good adhesive property, and can improve the problem of insufficient adhesion and failure of photo-curing adhesive, and prevent falling.

The application discloses a plant leaf biomimetic material with antifouling self-cleaning and spectrum simulation performance and a preparation method thereof. The plant leaf biomimetic material comprises, from bottom to top, a first liquid injection super-smooth porous elastomer layer, a hydrogel layer, a camouflage color fabric layer, a hydrogel layer and a second liquid injection super-smooth porous elastomer layer. The liquid injection super-smooth porous elastomer layer is a porous elastomer filled with silicone oil in voids. The first and second liquid injection super-smooth elastomer layers are the same or different. The hydrogel layer is one of a single-network hydrogel or a double-network hydrogel. The color of the camouflage color fabric layer is one of dark green, medium green, yellow green and light green. The plant leaf biomimetic material has excellent plant leaf spectrum simulation effect, can simulate the cell cavity tissue of plants, has antifouling and hydrophobic properties, can maintain excellent plant leaf spectrum simulation effect after rainwater washing, and can realize high-weatherability spectrum simulation.

The invention provides a self-early-warning-self-reinforcing spandex fiber and a preparation method thereof, and the method comprises the following steps: adding a compound M1, polyol, polyisocyanate and a catalyst into a solvent for reaction to obtain a polymer solution; precipitating the polymer solution in methanol, and drying the precipitate; and dissolving the dried sample in a solvent to prepare a spinning solution, and preparing the spinning solution into the spandex fiber. When the self-early-warning and self-reinforcing spandex fiber is subjected to external force, the internal bearing condition of the self-early-warning and self-reinforcing spandex fiber can be displayed in real time, the potential destructive external force of the self-early-warning and self-reinforcing spandex fiber can be subjected to self-early-warning, and on the other hand, a damaged part can be crosslinked to achieve a self-reinforcing effect. According to the method, the self-early-warning and self-reinforcing performance of the spandex fibers can be effectively guaranteed, and application of the spandex fibers in the fields of biomimetic materials, mechanical sensing, intelligent clothes and the like is facilitated.

The invention discloses a method for preparing a three-dimensional bionic structure through pulse laser assisted direct laser melting deposition, and relates to the technical field of additive manufacturing. In the additive manufacturing process, a continuous laser head advances at the constant speed v2 in the advancing direction; the pulse laser head conducts periodic reciprocating scanning at the speed v1 within the size range scanned by the continuous laser spots in the direction perpendicular to the advancing direction, the scanning path and parameters are controlled through software, a hole or a high residual compressive stress area is formed within the preset range of the material subjected to single-layer machining, and after single-layer machining is completed, the hole or the high residual compressive stress area is obtained. And the holes or the high residual compressive stress areas are embedded into the additive manufacturing layers to form single layers with bionic structure characteristics, and the single layers are overlapped layer by layer to form the material with three-dimensional bionic structure characteristics. According to the method, the three-dimensional biomimetic material with the directional structure characteristic is prepared by adopting the pulse laser in cooperation with the DLD additive manufacturing technology, and compared with a traditional method, the method has the beneficial effects that the structure, performance and size are accurate and controllable, and the like.

The present application belongs to the field of bionic technology, and particularly relates to a kind of bionic material loaded with YD monomer and its preparation method and application.The present application utilizes YD monomer composed of tyrosine (Y) and aspartic acid (D) to synthesize a kind of bionic material through reversible addition-fragmentation chain transfer (RAFT) polymerization. The bionic material can produce spatially adjacent binding pockets through the covalent bond of tyrosine (Y) and aspartic acid (D), and can capture two kinds of PTM (phosphopeptide and O-glycopeptide) simultaneously through synergistic interaction. The results of the present application show that the bionic material of YD monomer optimizes charge balance, the neutral phenolic group of Y (pKa ~ 10) and the negatively charged carboxylate of D (pKa ~ 3.9) together reduce the electrostatic repulsion with phosphopeptide, while maintaining target affinity; self-assembled into nanostructured porous framework can expose multivalent binding sites, and significantly improve capacity and selectivity through synergistic effect.

The invention relates to a buffer material based on a bionic metamaterial, a multifunctional buffer device and a preparation method of the buffer material. The buffer material is formed by arranging a plurality of cylinder unit arrays; the column body units are symmetrical and are provided with a plurality of hollow areas; the cross section of each cylinder unit comprises at least three layers of geometric units, and the geometric units of all the layers are combined in a nesting mode; the geometric units comprise a circle and a circular ring. The prepared buffering material has excellent energy absorption performance, the multifunctional buffering device has buffering and sensing functions, real-time monitoring of exercise loads can be achieved, the exercise special performance is improved, and personalized prevention of exercise injuries is achieved.

The present invention belongs to the field of batteries, specifically disclosed are a solid-state electrolyte, a preparation method therefor and a use thereof. The solid-state electrolyte contains a biomimetic material, an electrolyte salt, and a plasticizer. The biomimetic material is loaded with the electrolyte salt and the plasticizer. The biomimetic material comprises a monocyclic aromatic compound and a triazine nitrogen-containing heterocyclic compound. The monocyclic aromatic compound and the triazine nitrogen-containing heterocyclic compound are connected through hydrogen bonds. The biomimetic material has nanochannels with a diameter of 0.3-1 nm. In the solid-state electrolyte of the present invention, the monocyclic aromatic compound and the triazine nitrogen-containing heterocyclic compound are assembled through hydrogen bonds to form a biomimetic material having nanofluid transport channels with a diameter of 0.3-1 nm, thereby enabling rapid ion conduction of metal cations under nanofluid control, such that a solid-state battery containing the solid-state electrolyte of the present invention has a room-temperature lithium-ion conductivity of up to 17 mS / cm, a transference number of up to 0.7-0.8, and a voltage window of up to 4.5 V.

The invention belongs to the field of bionic materials, and particularly relates to a bionic concentric layered brick-mud structure micro-nano composite material and a preparation method thereof. The preparation method provided by the invention comprises the following steps: a) mixing an inorganic micro-nano sheet with a solvent to obtain a dispersion liquid; mixing the dispersion liquid with a binder solution to obtain mixed slurry; b) preparing a film from the mixed slurry, and then performing densification treatment on the prepared film to obtain a densified composite film; c) curling and forming the densified composite film to obtain a concentric layered cylindrical winding body; and d) dipping the concentric layered cylindrical winding body in a resin precursor solution, and then carrying out curing treatment to obtain the bionic concentric layered brick-mud structure micro-nano composite material. The preparation method provided by the invention is simple in process and suitable for large-scale production, and the prepared composite material not only can realize axial compression resistance and radial bending / torsion resistance, but also has excellent fatigue resistance.

The invention discloses a six-dimensional force control sensing bionic foot system and a control method.The system comprises a bionic foot body, a parallel driving mechanism, an ankle joint platform, a multi-point six-dimensional force sensing device and an ankle joint controller, and the multi-point six-dimensional force sensing device is used for obtaining information of the bionic foot body and the ankle joint platform; the ankle joint controller is used for adjusting the parallel driving mechanism, and the parallel driving mechanism controls the bionic foot main body through the ankle joint platform; the ankle joint controller fuses information transmitted by each six-dimensional force sensor, and then controls the parallel driving mechanism to adjust the ankle joint platform and the bionic foot main body. According to the invention, the triangular arch structure in the shape of the foot arch is combined with the flexible biomimetic material, so that larger-area contact and attachment can be realized on the uneven ground; information of three six-dimensional force sensors is fused through a model, data such as a zero moment point is calculated, and more sufficient feedback information is provided for attitude control; feedback information is also introduced, closed-loop dynamic feedback is formed, and the stability is improved again.

The application relates to a two-dimensional flower-shaped near-infrared responsive water-soluble photothermal conversion nanomaterial and a synthesis method and near-infrared application thereof. The two-dimensional copper sulfide nanosheet is prepared through a hydrothermal reaction, and gold nanoparticles are loaded on the edges of the two-dimensional nanosheet through gold-sulfur bonds, the content and molecular weight of the active agent on the surface of the nanosheet are controlled, the uniform loading of the gold nanoparticles is realized, and a composite material of a biomacromolecule and a biomimetic material modified inorganic nanomaterial is constructed. The nanomaterial prepared in the application has a unique two-dimensional flower-shaped morphology, has a wide spectrum absorption in the near-infrared region, and the maximum absorption peak extends to the NIR-IIa region, has the photothermal and photoacoustic performance in the near-infrared region, the material has effective brain tumor homing ability due to the T cell biomimetic membrane coating, the limitation of the nanomaterial in crossing the BBB is overcome, the tumor photothermal treatment effect is significantly enhanced, the biocompatibility is high and the material is non-toxic, no pollution is caused, the synthesis process is simple, the cost is low, and the material has a good treatment application prospect.

Disclosed is a kaempferol mesenchymal stem cell membrane biomimetic material capable of more accurately targeting a damaged tissue. The biomimetic nanomaterial is simple to prepare, high in universality, and suitable for large-scale production. The present invention uses mesenchymal stem cell membranes to improve the biocompatibility and targeting property of the carrier and prolong the circulation time of the drug in vivo. The biomimetic nanomaterial prepared by the present invention enables targeted delivery of kaempferol to the liver, providing a novel treatment method for acute liver failure ALF.

A thawing solution has 0.1-50 g of a biomimetic material for controlling ice, 0-1.0 mol L−1 of a water-soluble sugar, and balance of a buffer solution. The biomimetic material for controlling ice is a material for controlling ice having an ice-philic group and a hydrophilic group. The hydrophilic group is a functional group that can form a non-covalent interaction with water molecules, and the ice-philic group is a functional group that can form a non-covalent interaction with ice. Using the thawing solution and the thawing reagent prepared from the biomimetic material for controlling ice, which material has ice-philic and hydrophilic properties, the growth and recrystallization of ice crystals can be effectively controlled, and damage to cells or tissue caused by uncontrolled growth of the ice crystals during recovery can be significantly ameliorated.

The application relates to the field of biomimetic materials and discloses a self-repairing biological heart valve and a preparation method thereof. The biological heart valve comprises a tannic acid cross-linked pericardium modified by a polydopamine nanoparticle-loaded polyhydroxy hydrogel protective layer; the polydopamine nanoparticles are distributed on the surface of the tannic acid cross-linked pericardium and / or in the polyhydroxy hydrogel protective layer. The biological heart valve has good mechanical properties and can realize in-situ damage self-repairing under near-infrared light, which helps to improve the durability of the biological heart valve.

The invention relates to the technical field of biomimetic materials, polymer composite materials and polymer fibers, and discloses a preparation method of biomimetic assembled high-performance artificial spider silk fibers, which comprises the following steps: preparing primary gel fibers containing rigid network nodes and flexible polymer chains; stretching the primary gel fiber in a closed environment in which the temperature and the solvent vapor pressure are controlled at the same time; according to the environment, solvent molecules preferentially swell the flexible polymer chain, the rigid network nodes are kept stable, and the applied drawing force drives the flexible polymer chain to slide and axially orientate among the rigid network nodes. According to the method, the specific stretching environment is constructed, internal physical conflicts of stretching gain and structural damage are remodeled into a synergistic process, the situation that microdefects are generated at a rigid-flexible interface by stretching force is avoided, and a bionic rigid-flexible composite structure which is difficult to achieve in the prior art and has high integrity is obtained for final fibers.

The invention provides a method for preparing a hydrogel film on a non-conductive surface, and belongs to the technical field of biological material preparation. According to the hydrogel film forming method independent of the electrode surface, a hydrophilic non-conductive substrate is introduced into an electrolytic tank, solutions with different compositions are arranged on the two sides of the non-conductive substrate respectively, an electric field is applied, directional migration of polyelectrolyte molecules is achieved, the polyelectrolyte molecules are deposited on a non-conductive interface, and even if the deposition time is only one minute, the deposition time is not longer than 1 minute. And the generated film still has good uniformity. According to the invention, the dependence limitation of the traditional electrodeposition technology on the conductive substrate is broken through, and a universal platform is provided for constructing functional hydrogel on the surfaces of non-conductive materials such as glass, polymer films and the like. Compared with a traditional method, the method is rapid in preparation, simple in equipment, mild in operation and suitable for various natural and synthetic polyelectrolyte systems, and has huge application potential in the field of biomimetic material preparation.

The invention relates to the technical field of leather preparation, in particular to a PBS-based bionic texture bio-based leather 3D printing preparation method, raw materials comprise the following components: poly (butylene succinate) (PBS), bio-based polyester polyol, bamboo fibers, a biodegradable elastomer (PCL elastomer) and bionic texture master batches; the components and the proportion are as follows: the proportion of the poly (butylene succinate) is 50 parts; the ratio of the bio-based polyester polyol is 20 parts; the proportion of the bamboo fibers is 15 parts; the proportion of the biodegradable elastomer is 10 parts; the proportion of the bionic texture master batch is 5 parts; comprising the following steps: 1, pretreating raw materials; 2, mixing the raw materials; step 3, a granulation process; 4, a 3D printing link; 5, a post-treatment stage; the invention aims to solve the problems that most existing biomimetic materials adopt non-degradable petroleum-based raw materials, pollution is easily caused after the biomimetic materials are discarded, the performance is unbalanced, and the material performance shows a remarkable binary opposite characteristic.

The invention relates to a preparation method of a shape memory reversible bionic adhesion material, and belongs to the technical field of bionic materials. The method comprises the following steps: preparing a male die from PVC gel, and copying to obtain a PDMS female die; mixing the shape memory polymer matrix, the curing agent and the toughening copolymer to form an epoxy resin precursor; and curing in a PDMS (Polydimethylsiloxane) female die by a template method to obtain the adhesive material with the microstructure array. The material can realize reversible adhesion switching under thermal stimulation through a buckling lodging mechanism: when the material is heated to a temperature above a glass-transition temperature, the microstructure is softened, buckled and lodged, so that the contact area is increased, and strong adhesion is generated; after cooling, hardening and keeping the state; and the shape is recovered by heating again, so that low-energy-consumption desorption is realized. The process is simple and convenient, and the material has high adhesion strength, quick response, long service life and good adaptability and can be widely applied to the fields of intelligent robots, precision control, flexible electronics and the like.

The invention discloses a bionic floating type hydro-fluctuation belt phytoremediation system capable of adaptively adjusting the water level, and relates to the field of ecological remediation and biomimetic material application. A modular floating unit comprises a bionic buoyancy base, and a closed cavity communicated with an external water body is formed in the bionic buoyancy base; the closed chamber is a drainage bag and air bag composite system for adjusting buoyancy to maintain the ecological planting layer at a proper ecological water level; an ecological planting layer and a connecting and anchoring unit; the problem that a traditional fixed restoration structure in water level periodic fluctuation areas such as a reservoir area, a river channel and a lake is difficult to maintain ecological stability is solved, and through the synergistic effect of the bionic buoyancy base and the flexible anchor, the system can automatically, stably and vertically ascend and descend along with water level fluctuation; the problems that a traditional fixed project is not suitable for a violent hydrological change area and an existing floating island is not suitable for the violent hydrological change area are fundamentally solved, and a continuous and stable growth platform is provided for plants in the extreme dry-wet alternation environment of the hydro-fluctuation belt.

The invention discloses an efficient energy absorption and shock wave attenuation protection structure based on a chain A framework, and relates to the field of protection structures and impact energy absorption, in particular to the efficient energy absorption and shock wave attenuation protection structure based on the chain A framework. The problems that a traditional rigid armor cannot be attached to human joints, the motion freedom degree is limited, energy absorption of a soft material is insufficient under high-speed impact, and the damage risk of a bionic material is high under low-energy impact are solved. The panel is composed of a panel body and a chain A type array. The chain A type array is composed of a plurality of chain A type grillwork units, and the chain A type grillwork units are connected through interlocking points. And the panel covers the impact incident side of the chain A type array. The invention is applied to the field of armor protection.

The invention provides a mechanical gradient bionic skin multi-layer injection mold and a forming method. The mechanical gradient bionic skin multi-layer injection mold comprises a fixed mold plate and a movable mold plate. The mold core slides in the center of the movable mold plate in the cavity, a groove corresponding to a product in shape is formed in the fixed mold plate, and an initial cavity is formed between the mold core and the bottom face of the groove. According to the method, a special mold with a movable mold core is adopted, biomimetic materials with different hardness and elasticity moduli are sequentially injected into the same cavity by accurately controlling mold closing, injection molding and mold opening actions, and one-time forming from epidermis to dermis and subcutaneous tissue is achieved. The bionic skin with the structure of'soft epidermis-tough dermis-elastic subcutaneous tissue 'and the mechanical property in gradient change is manufactured in a one-time forming period by accurately controlling mold actions and a multi-material sequential injection molding process, industrialization is easy, and more reliable ergonomic data is provided for design of safety protection and military equipment.

The present application relates to a kind of preparation method of shape memory reversible biomimetic adhesive material, belong to biomimetic material technical field.The method includes: with PVC gel preparation male die, copy PDMS female die;Shape memory polymer matrix, curing agent and toughening copolymer are mixed into epoxy resin precursor;By template method in PDMS female die solidification, obtain the adhesive material with microstructure array.The material can realize adhesive reversible switching by flexion mechanism under thermal stimulation: heating to above glass transition temperature, microstructure softening flexion and increase contact area, produce strong adhesion;After cooling, hardening keeps state;Again heating then shape recovery, realize low energy consumption detachment.The present application process is simple, and material has high adhesive strength, fast response, long life and good adaptability, can be widely applied in intelligent robot, precision manipulation and flexible electronic etc.Field.

The invention provides an extraction method of perna viridis foot vesicles, which comprises the following steps: S1, respectively sampling tissues of a near-end region and a far-end region of a foot, and grinding to obtain a foot tissue homogenate; s2, removing tissue fragments and other impurities by adopting a multi-stage filtration mode to obtain a foot vesicle crude extract; and S3, further removing organelles and other impurities by adopting a multi-time centrifugation mode to obtain purified near-end region vesicles and far-end region vesicles of the feet. According to the method, crude extraction of the vesicles is carried out in manners of multiple times of filtration, low-speed centrifugation, filter membrane filtration and the like, and the vesicles can be obtained under the conditions of less centrifugation times, rotation speed and time, so that the extraction process of the vesicles is simplified, and the activity of biomacromolecules in the vesicles is maintained to the maximum extent; the method can be used in the scientific research fields of byssus formation mechanism research, byssus biomimetic material research and development and the like.