The invention discloses a preparation method of a biomimetic material, in particular relates to a method for preparing the composition material of poly-aspartic acid or the derivatives, chitosan, lecithin and calcium-phosphate compound. The method first compounds poly-aspartic acid or the derivatives with different side chains, and then makes the poly-aspartic acid or the derivatives with different side chains, chitosan, lecithin, calciferous solution and crosslinking agent mix, react and settle down under a certain temperature and pH value. The obtained product has the properties of biomimetic membrane materials and is an environment-friendly biomimetic material. The material has the function of absorbing heavy metals and some organics, can be used for removing heavy metals, chlorinated hydrocarbon, organic pigment and dye, and can be widely applied to pharmaceutical industry, food industry, printing and dyeing industry, waste water treatment and other fields.