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94 results about "Biosecurity" patented technology

Biosecurity, as originally conceptualized, is a set of preventive measures designed to reduce the risk of transmission of infectious diseases in crops and livestock, quarantined pests, invasive alien species, and living modified organisms. The emerging nature of biosecurity threats means that small scale risks blow up rapidly, thus an effective policy becomes a challenge for there are limitations on time and resources available for analysing threats and estimating the likelihood of their occurrence.

Aquatic product water quality multi-parameter real-time on-line monitoring system

The present application relates to the technical field of aquaculture monitoring and regulation, and discloses a water quality multi-parameter real-time online monitoring system. The system comprises a multi-source data acquisition module for obtaining and denoising water quality data; a time sequence feature analysis module for generating multi-dimensional feature clusters containing the correlation of various parameters; an anomaly identification module for dynamic deviation compensation, monitoring sub-domain demarcation and key parameter extraction; a collaborative regulation module for constructing a regulation decision unit to generate a multi-parameter collaborative regulation strategy; and an iterative correction module for correcting the regulation strategy to output real-time adjustment instructions. An early warning module is also provided for biological safety assessment and early warning and activation of the emergency intervention mechanism. The system can accurately monitor the multi-parameters of the water quality of aquaculture in real time, realize intelligent regulation and biological safety early warning, effectively improve the yield and quality of aquaculture, reduce the risk of aquaculture, and promote the sustainable development of the industry.
Owner:SHENZHEN YUSHENGFA TECHNOLOGY IND CO LTD

Disinfectant verification method based on Jerlin code

ActiveCN121616316ACommerceTransmissionDisinfectantBiological potential
The invention belongs to the technical field of data processing, and relates to a disinfectant verification method based on Jerlin codes. The invention aims to solve the problem of biological potential safety hazards that the identity and the state are separated in the anti-counterfeiting verification of the existing disinfectant, and the titer of the liquid medicine falls off the threshold value due to environmental factors cannot be identified. The method comprises the following steps: in response to a code scanning operation, analyzing a Jerlin code to obtain a factory fingerprint, and splicing cloud logistics and terminal storage data to form a full-link environment monitoring sequence; calculating an environment pressure acceleration coefficient of each time slice by using a nonlinear kinetic model, and evaluating the damage degree of the environment to chemical properties; calculating accumulated chemical loss and residual titer based on the coefficient; and comparing the residual titer with a threshold value, and if the residual titer reaches the standard, generating a dynamic hash token containing titer information for cloud verification. According to the invention, deep combination of physical efficacy and digital verification is realized, and the use safety and reliability of the disinfectant are greatly improved under the condition that an expensive sensor is not needed.
Owner:JIANGSU KANGBAT BIOLOGICAL ENG CO LTD +1

Clinical laboratory specimen full-process tracking and biological safety early warning management system

The invention discloses a clinical laboratory specimen full-process tracking and biosafety early warning management system, and relates to the technical field of medical biosafety management, and the system comprises a multi-modal data collection module which integrates various devices and comprehensively collects specimens and related data; the intelligent identification and verification module adopts an advanced algorithm to process the image, completes compliance judgment and traceability verification, and outputs a comprehensive data packet; the dynamic risk assessment module calculates a risk coefficient and matches a five-color early warning level; the grading early warning and linkage disposal module determines an early warning grade, quantifies disposal intensity, and realizes visual management and control and closed loop; according to the method, accurate determination of specimen compliance and full-process traceability verification are realized through deep analysis of an algorithm, data quality and management accuracy are improved, meanwhile, a dynamic risk assessment mechanism is constructed, risks are graded accurately, disposal intensity is quantified, risk visual management and control and closed-loop management are realized, and normalization and controllability of biological safety management are enhanced.
Owner:BEILUN DISTRICT PEOPLES HOSPITAL OF NINGBO CITY

Method and apparatus for improving biosafety of waste transport processes

Disclosed herein is a waste encapsulation method comprising: (i) placing an adhesive composition into a compactor; (ii) placing one or more flexible containers containing waste material into the compactor; (iii) heating the binder composition to liquefy the binder composition and embedding the waste into the liquefied binder composition to form a coated mixture; and (iv) compacting the coating mixture and forming a hydrophobic composite article containing the waste material.
Owner:INNER MONGOLIA MENGAO ENVIRONMENTAL TECHNOLOGY CO LTD

Negative pressure isolation living body microscope experiment box

This invention provides a negative pressure isolation live microscope experimental box. The experimental box, through its closed negative pressure design, ensures the biosafety of experiments with pathogens of BSL-2 level and above, meeting the requirements of the safety committee review. At the same time, its innovative box-type integrated window structure eliminates the vibration torque caused by animal movement in traditional suspended windows from a mechanical design perspective, providing unparalleled stability for high-precision imaging. Ultimately, it makes it possible to safely and stably conduct live microscopic studies of highly pathogenic infection models in a conventional laboratory.
Owner:SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES

Method for monitoring and evaluating the transmission risk of pathogenic bacteria in poultry farm manure

PendingCN122357748ABiotechnologyAnimal science
This invention provides a method for monitoring and evaluating the risk of pathogenic bacteria transmission in poultry farm feces, belonging to the field of livestock and poultry biosecurity control technology. The method includes evaluating the risk of Salmonella transmission during the poultry physiological cycle, assessing the risk of antibiotic resistance associated with drug administration behavior, and monitoring the function during composting based on microbial community structure and metabolic function. This invention can accurately locate the highest-risk nodes of pathogen contamination and antibiotic resistance evolution during the breeding cycle, solving the problem of inaccurate identification of risk sources in existing technologies and avoiding poultry product contamination due to missed risk assessments. It overcomes the single-dimensional limitation of existing technologies that only detect the quantity of pathogens, comprehensively evaluating pathogen risk from phenotypic, molecular, and functional levels. The assessment results are more in line with the actual biosecurity needs of poultry farming, ultimately reducing the safety risks of poultry product contamination and the spread of antibiotic resistance.
Owner:ZHEJIANG UNIV ZHONGYUAN INST

Intelligent monitoring method, device and equipment for livestock breeding and storage medium

The invention discloses an intelligent monitoring method, device and equipment for livestock breeding and a storage medium, and relates to the technical field of intelligent monitoring of livestock breeding, and the method comprises the steps: S100, data collection and time synchronization; s200, carrying out adaptive denoising and cross-modal feature extraction; s300, carrying out individualized baseline modeling and drift self-adaption; s400, performing multi-scale event association and weak causal identification; s500, risk grading and executable intervention suggestion generation; according to the method, priority disposal decision and resource optimization are oriented to economic and biological safety, namely, path confidence scores and node influence probabilities are integrated into calculation of influence ranges and expected intervention cost, and confidence-driven uncertainty premium is reflected in the cost, so that alarms not only reflect biological risks, but also reflect uncertain premium in the cost; the potential economic influence and the operation cost can be quantified; based on the multi-dimensional score, the method can preferentially put limited veterinarians and epidemic prevention resources, medicines and isolation measures into a cluster which contributes to group health and productivity loss risk to the greatest extent.
Owner:济南市公园发展服务中心

Safe reproduction method for African swine fever virus nucleic acid positive pig farm

The invention relates to the technical field of animal epidemic disease prevention and control and farm biosafety, in particular to a safe reproduction method for an African swine fever virus nucleic acid positive pig farm. A pollution area is determined through accurate risk assessment and gridding dynamic management, environment purification is achieved by combining thorough cleaning and disinfection with hardware upgrading and process reconstruction, and finally, a positive field is successfully converted into a negative field capable of achieving full-load stable production by relying on a triple guarantee system of environment monitoring, microbiological assessment and sentinel pig biological verification. According to the invention, through accurate risk assessment and dynamic grid management, visual positioning of a pollution area is realized; high-efficiency cleaning and disinfection are combined with hardware upgrading and process reconstruction, so that viruses are thoroughly removed, and transmission is blocked; based on environmental nucleic acid, microbial culture and sentinel pig triple verification, biological safety and reliability are ensured. Finally, the positive field is successfully converted into a negative field for stable production, and a systematic and reproducible safe reproduction scheme is provided for the industry.
Owner:LIAOCHENG UNIV

LAMP (loop-mediated isothermal amplification) primer group for detecting four quarantine viruses, kit, method and application of LAMP primer group

The invention discloses an LAMP (loop-mediated isothermal amplification) primer group, a kit and a method for detecting four quarantine viruses and application of the LAMP primer group. Belongs to the technical field of molecular biology and plant quarantine. Aiming at conserved gene regions of bean pod mottle virus, tobacco ringspot virus, tomato ringspot virus and southern bean mosaic virus, a specific target sequence is screened through bioinformatics analysis, an LAMP primer group is designed, and the nucleotide sequence of the LAMP primer group is shown as SEQ ID NO.1-22. Furthermore, the screened primer group is combined with a micro-fluidic chip technology to construct a detection kit capable of synchronously detecting the four viruses, so that the specific identification of the four target viruses is realized. The kit has the advantages of rapidness, sensitivity, specificity, simplicity and convenience in operation and the like, the sensitivity can reach 10 <-10 > Copies / mu L, and the kit is suitable for high-throughput rapid screening of quarantine viruses in imported soybeans on port sites and has important significance in guaranteeing national biosafety.
Owner:湛江海关技术中心

Recombinant humanized type III collagen, preparation methods and applications

ActiveCN121873211BWound dressingEngineering
This invention discloses recombinant humanized type III collagen, its preparation method, and its applications, belonging to the field of medical materials technology. The amino acid sequence of this recombinant humanized type III collagen is any one of SEQ ID No. 2-6. Compared to traditional extraction methods, the amino acid sequence of this recombinant protein is highly consistent with that of natural human proteins, completely avoiding the biosafety risks of pathogens, prions, etc., that may exist during animal-derived extraction, while also exhibiting lower immunogenicity. Furthermore, this protein effectively maintains the natural biological activity and stability of collagen. When used as a wound dressing, this material can efficiently promote cell migration, spreading, and proliferation, accelerate tissue regeneration and wound healing, while possessing excellent biocompatibility, controllable degradation, and low immunogenicity.
Owner:SHANDONG YITENON BIOTECHNOLOGY CO LTD

A viral aerosol sampling patch for face masks and its detection method

This invention relates to the fields of environmental monitoring and biosafety technology, and in particular to a viral aerosol sampling patch for face masks, comprising: a capture layer for intercepting viral aerosol particles in the air; a culture layer disposed inside the capture layer, the culture layer comprising a culture unit supporting the virus to maintain activity and replicate in the presence of a host, a host bacterium sensitive to the virus, and a visual indicator indicating viral replication or host response; and a base layer disposed inside the culture layer; the sampling patch is fixed to the face mask through the base layer, and viral aerosol collection is achieved without external power through the capture layer, and countable detection results are generated after sampling through the culture layer; utilizing the airflow and humidity conditions naturally formed during wearing, effective interception, activity preservation, and visual detection of viral aerosols are achieved without complex equipment and additional operating steps, and the operation is simple and repeatable.
Owner:FIRST HOSPITAL OF QINHUANGDAO

Laminated caged laying hen breeding management method and system, terminal and medium

The invention discloses a stacked caged laying hen breeding management method and system, a terminal and a medium, and relates to the technical field of breeding management. According to the main technical scheme, individual physiological status information of all laying hens in a breeding area is obtained, and when the individual physiological status information does not meet a preset health status threshold value, a physical mark is attached to the body surface of a target laying hen to be processed; and processing information is generated according to the identification information of the physical marks and the breeding position information of the breeding area where the target laying hens to be processed are located. The method is expected to achieve the purposes of finding the abnormal health state of the laying hens in an early stage, further conveniently and quickly isolating the abnormal health laying hens, greatly reducing the risk of cross infection, improving the biological safety level of a henhouse and reducing the outbreak probability of group epidemic situations. And meanwhile, the aims of enabling the laying hens with abnormal health to be visualized and recognizable in a dense group, so that a worker can quickly lock specific abnormal individuals in the dense group during subsequent processing, thereby shortening the positioning time of the worker and improving the response speed are fulfilled.
Owner:GUANGAN GAOYAKOU ECOLOGICAL AGRI CO LTD

Automatic uniform mixing type medicine adding device for plug tray stockline

The utility model relates to the technical field of livestock breeding, and discloses an automatic uniform mixing type medicine adding device for a plug tray stockline, which comprises a stirring box arranged on the plug tray stockline; the stirring assembly comprises a plurality of stirring pieces and a plurality of conveying pieces, the stirring pieces and the conveying pieces are arranged in the stirring box, the stirring pieces and the conveying pieces are arranged in a staggered mode and connected end to end, the inlet end of the stirring piece located at one end communicates with one end of the tray plugging material line, and the discharging end of the conveying piece located at the other end communicates with the other end of the tray plugging material line; the medicine adding assembly comprises a medicine adding bin and a medicine adding part, the medicine adding bin is fixedly connected to the stirring box and communicates with the inlet end of the stirring part located at one end, and the medicine adding part is arranged in the medicine adding bin and used for controlling medicine output. Normal conveying of feed in a feed line is not affected, the feed can be fully mixed with medicine after passing through the device, and the problems that manual medicine adding is high in cost, low in efficiency and not beneficial to biological safety protection and the medicine and the feed cannot be fully mixed are solved.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

A high-temperature sterilization process and system for dead livestock and poultry

The application discloses a kind of high-temperature sterilization treatment processes and systems of sick and dead livestock and poultry, belong to sick and dead livestock and poultry processing technical field, this kind of high-temperature sterilization treatment processes and systems of sick and dead livestock and poultry, including ground mechanism, hydraulic flap mechanism, crushing mechanism, transport mechanism, processing mechanism and gas degradation mechanism.The application is realized through the setting of ground mechanism, hydraulic flap mechanism, crushing mechanism and processing mechanism, contactless transfer and low manual intervention in the process of sick and dead livestock and poultry processing, to significantly reduce the risk of cross contamination, improve operation efficiency and epidemic prevention reliability, the application is realized through the setting of processing mechanism, gas degradation mechanism and flow guide mechanism, closed loop processing of sick and dead livestock and poultry, high-temperature sterilization kills pathogen completely, guarantees biological safety, and realizes low energy consumption, environmental protection stability, airflow uniform distribution and high mass transfer efficiency of biodegradation, whole closed no leakage, epidemic prevention and environmental benefits are remarkable, safe and reliable operation.
Owner:CHENGDU KENONG ANIMAL HARMLESSNESS DISPOSAL

The invention relates to a space-time specific promoter OsSULTR1 of a rice endogenesis. 3pro and application thereof

The invention belongs to the technical field of agricultural biology, and particularly relates to a rice endogenous space-time specific promoter OsSULTR1; the invention discloses 3pro and application thereof. The promoter OsSULTR1 is characterized in that the promoter OsSULTR1 The nucleotide sequence of 3pro is as shown in SEQ ID NO. 1. The invention provides an OsSULTR1; 3pro is a space-time specific expression regulation element from rice, can efficiently and stably drive a target gene to be expressed in a plant callus, and can realize targeted efficient and stable expression in root and stem tissues in a plant vegetative growth period. The promoter can effectively replace a non-plant-source promoter commonly used in existing plant genetic engineering, has an important industrial application value in the field of plant genetic engineering, and not only can improve the targeting and stability of target gene expression in transgenic plants, but also can improve the yield of the transgenic plants. And the potential biological safety risk of the transgenic plant caused after the exogenous DNA is introduced into the plant genome can be obviously reduced.
Owner:NATIONAL TECHNOLOGY INNOVATION CENTER FOR SALT-ALKALI TOLERANT RICE AT SANYA +1

A portable ultraviolet and hydrogen peroxide synergistic sterilization device for biosafety sample handling packaging

ActiveCN224585087UImprove disinfection effectSolve the problem of inactivationAerosol MistBiology
This invention discloses a portable UV and hydrogen peroxide co-sterilization device for biosafety sample collection and delivery packaging. The device employs a double-layered insulated enclosure, with a UV sterilization lamp at the top and an atomizing hydrogen peroxide nozzle on the inner wall. The atomizing nozzle sprays micron-sized aerosol particles to achieve omnidirectional dispersion of the aerosol medium within the sealed space, combined with the UV light source arrangement design to eliminate sterilization dead zones. An adjustable partition inside the enclosure allows for flexible separation of samples of different sizes, preventing cross-contamination. Ventilation holes in the enclosure walls balance internal and external air pressure, ensuring product safety. An environmental monitoring module at the bottom monitors temperature and humidity data in real time and displays it on a screen outside the enclosure, providing visualization of the internal temperature and humidity. This invention facilitates dual sterilization and is adaptable to various pathogenic microorganism disinfection scenarios, possessing characteristics such as impact resistance, corrosion resistance, non-destructive sample handling, and environmental friendliness.
Owner:长沙海关技术中心 +1

A digital management system and method for bio-safety access of a pig farm

PendingCN122390900APig farmsVideo monitoring
The present application relates to the technical field of livestock safety management, and particularly relates to a digital management system and method for biological safety access of a breeding pig farm. The system is cooperatively operated by a management platform, a mobile terminal, a video monitoring system and an Internet of Things device, controls the whole process of personnel, vehicles, materials, food and feed entering and leaving the breeding pig farm, and builds an integrated closed-loop management mechanism of "plan, execution, supervision, rectification and data". Through plan reporting and approval, the orderly arrangement of access activities is realized. Through job reporting and standard execution, the key operation process is standardized. Through video monitoring and parameter collection, the whole process is supervised. Through the negative list and rectification mechanism, a closed loop of problem processing is formed. Through data collection and report analysis, the access management information is visualized and decision support is realized. The method can effectively improve the biological safety management level, reduce the risk of disease transmission and improve the efficiency of breeding pig breeding.
Owner:WENS FOODSTUFF GROUP CO LTD

A method for tracing the spread of the alien invasive plant solidago canadensis with nursery stock

The present application relates to the technical field of biological safety and ecological protection, and discloses a method for tracing the spread of alien invasive plant Solidago canadensis with nursery stock, which comprises the following steps: collecting and recording the geographic coordinates, root base soil color, plant species in the root base soil range, and specification attribute data of the nursery stock in the planting area of the nursery stock suspected to carry Solidago canadensis and the spread points caused by the transportation of the nursery stock; identifying the color of the root base soil by using the Munsell color system and three attributes of color; and adopting a three-step analysis strategy to accurately identify the source of Solidago canadensis carried by the nursery stock, evaluating the spread risk of Solidago canadensis according to the tracing result, and putting forward targeted prevention and control suggestions for source control and early monitoring and early warning. The tracing analysis method can identify the region-specificity of the four types of data, i.e., root base soil, associated plant species, diameter, and branch height, thereby ensuring the accuracy of the tracing result.
Owner:INST OF PLANT PROTECTION CHINESE ACAD OF AGRI SCI +1

Aerosol high efficiency sampling device and method

This invention relates to a high-efficiency aerosol sampling device and method, belonging to the fields of environmental monitoring and biosafety technology. It includes a U-shaped ventilation tube with a flat bottom, an air inlet at the top of the left longitudinal tube, and an air outlet at the top of the right longitudinal tube. A fan is installed at the air inlet to achieve high-flow-rate air introduction. The inner side of the flat section of the U-shaped ventilation tube is filled with sampling liquid, and a temperature control component is installed on the outer side of the flat section. This invention provides a device and method that can significantly increase the contact area through an evaporation-condensation cycle without reducing airflow, achieving high-throughput and high-efficiency microbial aerosol sampling. It solves the problems of low airflow, limited contact area between aerosol and sampling liquid, and insufficient sampling efficiency in existing aerosol sampling technologies.
Owner:CHINESE ACAD OF INSPECTION & QUARANTINE +2

A non-destructive detection method for grouper nervous necrosis virus based on correlation between water body virus load and fish tissue virus load

The application discloses a kind of based on water body virus load and fish body tissue virus load correlation grouper nervous necrosis virus nondestructive testing method.The method is through optimizing the concentration condition of virus in aquaculture water, realize the efficient concentration and quantification of water body virus load, then combine water-water aquaculture animal virus load correlation model, indirectly and nondestructively assess the virus infection state of aquaculture animal.The application detects water environment instead of detecting animals itself, realizes nondestructive, dynamic, early warning monitoring of the health status of aquaculture animal population, with the advantages of low cost, simple operation, frequent implementation, etc., and has important application value in aquatic disease prevention and control, good seed selection and biological safety management.
Owner:HAINAN UNIV

Tray-type article cleaning apparatus

The present application discloses a kind of tray class object cleaning equipment, to solve the problem of secondary pollution in existing cleaning technology, high energy consumption and big biological safety risk.It includes frame body and gas collection cover body, cover in sequence along conveying device setting cleaning station, rinsing station and purging station.And set a set of closed loop air collection purification system based on single fan: fan from cleaning station through negative pressure suction pipe suction contaminated air, the air enters the closed fan cover after demisting, adsorption and dehumidification;Fan uses its own operating waste heat to heat the inhaled clean air, and sends it to the purging station as high-temperature purge gas flow;Most of the purge gas flow returns to the cleaning station to form an internal circulation in the cover, and forms a negative pressure barrier at the inlet, thereby controlling the dispersion of water mist, aerosol and odor from the source.The present application has the advantages of compact structure, zero dispersion control of pollutants, significant environmental protection, energy saving and safety.
Owner:QINGDAO JIECHENG PLASTIC METAL CO LTD

Intelligent acousto-optic joint dispersing system based on biological safety threshold regulation and control

The invention discloses an intelligent acousto-optic joint dispersing system based on biological safety threshold regulation and control, and relates to the technical field of crossing of biological safety and intelligent ecological regulation and control. The system comprises a regional ecological characteristic quantification module which generates a non-linear threshold distribution sequence through an improved whale optimization algorithm, and adapts to ecological characteristics of an early warning area, a warning area, a repelling area and an observation area; the distributed sensor network realizes accurate acquisition and noise reduction of biological data; a biological data multi-scale noise reduction module dynamically optimizes a threshold value; the biological invasion risk prediction module analyzes the invasion probability and verifies the ecological bearing compliance; the intelligent acousto-optic regulation and control module is based on a PID neural network and a sliding mode control fusion algorithm, and combines model prediction control to realize acousto-optic power dynamic adjustment and regional linkage in a multi-constraint scene. According to the system, through multi-module cooperation, the real-time response capability and ecological adaptability of biological activities are improved, the scientificity and stability of the dispersing effect are enhanced, the misjudgment risk is reduced, and ecological safety and efficient operation of the system are guaranteed.
Owner:SHENZHEN HENGXINSHENG TECHNOLOGY CO LTD

Livestock and poultry farm veterinary microorganism aerosol collection system and analysis method

The invention belongs to the technical field of aerosol collection and analysis, and discloses a livestock and poultry farm veterinary microorganism aerosol collection system and analysis method. The system comprises a space-time environment perception scheduling module, a multi-source data sampling cooperative control module and a multi-source data fusion standardization module, a microorganism sequence in a space-time database is automatically analyzed, an active microbiome analysis report is obtained, and the multi-source data fusion standardization module is established based on the space-time database and the active microbiome analysis report. The method comprises the following steps: acquiring a pathogen transmission dynamic simulation report, performing simulation calculation according to a fluid mechanics algorithm and an infection risk model to obtain a pathogen transmission dynamic simulation report, converting the pathogen transmission dynamic simulation report, and comparing a conversion result with an infection threshold interval to obtain a biological safety risk early warning report and a biological safety strategy optimization suggestion report. The method has the remarkable advantages of being high in basic data supporting capacity, high in biological information analysis truth degree and good in intervention strategy foresight effect.
Owner:INST OF ANIMAL HUSBANDRY & VETERINARY MEDICINE ANHUI ACAD OF AGRI SCI

Visual correction system and method for biosafety cabinet operation training

The invention relates to a visual correction method for biosafety cabinet operation training. The method comprises the following steps: establishing a biosafety cabinet body coordinate system and dividing the biosafety cabinet body coordinate system into a clean area, an operation area, a waste area and a restricted area; establishing a standard comparison model containing an action type, an object type, an allowable area and attitude constraint based on a standard operation instruction; collecting an operation process and generating an action event sequence on a unified time axis; and matching the action event with a standard comparison model item by item, and triggering visual warning and voice prompt when deviation exists. Further, a visual identification device, an inertial measurement unit and a depth / distance sensing device are adopted for synchronous fusion, and event confidence is output; space, attitude and time tolerance levels are introduced to reduce false alarms; according to the method, the SOP steps are set, scoring fields and scoring rules are set for the SOP steps, step scores and total scores are automatically calculated, and a traceable report is generated, so that the consistency and normalization of the training process are improved, and the biological safety risk caused by operation deviation is reduced.
Owner:SUN YAT SEN UNIVERSITY SHENZHEN +1

Tobacco alanine aminotransferase gene NtALAAT2 and application thereof

This invention discloses a tobacco alanine aminotransferase gene, NtALAAT2, and its applications, belonging to the fields of plant genetic engineering and tobacco genetic breeding technology. The nucleotide sequence of the NtALAAT2 gene is shown in SEQ ID NO.1, and the amino acid sequence of its encoded protein is shown in SEQ ID NO.2. This invention reveals for the first time that the expression level of the endogenous NtALAAT2 gene in tobacco is negatively correlated with proline content. By reducing the expression level of this gene, the proline content in tobacco can be effectively increased, thereby enhancing the tobacco's tolerance to drought and / or soil salinization stress, without significantly adversely affecting the normal growth and development of the plant. This invention employs an endogenous gene regulation strategy, avoiding the biosafety risks of introducing exogenous genes, and provides a new gene resource and efficient technical pathway for breeding new tobacco varieties with high stress resistance.
Owner:CHINA TOBACCO YUNNAN IND

RPA-CRISPR method for rapidly detecting pathogens in air

The invention belongs to the technical field of environmental biological safety monitoring, and particularly relates to an RPA-CRISPR method for rapidly detecting pathogens in air. According to the invention, a two-step detection strategy integrating RPA isothermal amplification and CRISPR detection is established; the method specifically comprises the following steps: firstly, acquiring genome DNA of an air sample, and carrying out specific amplification on a trace target by utilizing an RPA technology; then, a product is introduced into a CRISPR-Cas12a system, and the trans-shear activity is recognized and activated by utilizing the specificity of crRNA, so that signal cascade amplification is realized. Pseudomonas aeruginosa is used as a model pathogen, and a primer and probe combination is designed aiming at a specific gene of the pseudomonas aeruginosa. Results show that the method can complete detection within 10-15 minutes at the soonest, the lowest detection limit can reach a single copy level (100 copies / L), and the method has the advantages of high environmental interference resistance, high sensitivity and no need of large instruments, and can meet the on-site rapid screening requirements of air pathogen aerosol in public places, medical environments and other scenes.
Owner:GUANGZHOU NAT LAB +1

Biosafe multi-dimensional data management system and method

The invention discloses a biosecurity multi-dimensional data management system and method, and relates to the technical field of biosecurity data management, and the system comprises a data risk grading module which is used for carrying out the risk feature extraction and risk grading of biosecurity original data; the differential privacy perturbation module is used for configuring differentiated privacy budget parameters according to the risk levels; the trusted execution environment deployment module is used for constructing a TEE instance; the under-chain instant fusing module is used for instantly executing permission freezing operation in the TEE instance and generating a permission fusing voucher; the data storage generation module is used for generating a verifiable storage record; the block chain asynchronous synchronization module is used for asynchronously synchronizing the evidence storage record and the fusing certificate to a block chain network for consensus confirmation; according to the method, the sensitive data leakage risk is solved through the differential privacy technology, millisecond permission fusing is achieved through the TEE technology, and the problems of sensitive information leakage and permission control delay are solved.
Owner:ZHENGZHOU HUAJUN TECH

Potato late blight biocontrol strain as well as biocontrol inoculant and application thereof

PendingCN121406528ABiocideBacteriaBiotechnologyPhytophthora sp.
The invention provides a potato late blight biocontrol strain as well as a biocontrol inoculant and application thereof, and belongs to the technical field of biocontrol bacteria. The invention discloses a bacillus safeensis strain B1, and the biological preservation number of the bacillus safeensis strain B1 is CGMCC (China General Microbiological Culture Collection Center) No.36024. The invention also provides a biocontrol bacterium composition which is prepared by compounding the Leifsonia sp. Strain L1 alone or by combining the Leifsonia sp. Strain L1 with the Leifsonia sp. Strain L6 and the strain B1. The strain B1 has good activity of inhibiting phytophthora infestans, meanwhile, the biocontrol bacterium composition not only further improves the antibacterial activity of the strain B1, but also shows that the biocontrol bacterium composition can effectively reduce the disease index of potatoes, and compared with the single-phase strain B1, the biocontrol bacterium composition can effectively improve the prevention effect of potato late blight.
Owner:CHINA AGRI UNIV

Biological material waste sterilization and collection device suitable for interior of biological safety cabinet

The invention discloses a biological material waste sterilization and collection device suitable for a biological safety cabinet, and relates to the technical field of biological safety. Comprising a base, a collecting cylinder is fixedly arranged on the base, the collecting cylinder is sleeved with a detachable protective shell, a collecting opening is formed in the top of the protective shell, and a movable sealing plate controlled by an infrared induction device is arranged in the collecting opening; a top ultraviolet lamp is arranged on the periphery of the collecting opening, and a disinfection spraying device communicated with the disinfection liquid adding container is arranged below the collecting opening; the inner wall of the protective shell is provided with a hook used for fixing a garbage bag, an automatic tying and sealing device used for automatically tying an opening of the garbage bag and an internal ultraviolet lamp arranged around the collecting cylinder. Through multiple sterilization design of ultraviolet disinfection and spray disinfection, an automatic tying and sealing function and intelligent sealing control, whole-course isolation and efficient sterilization of infectious biological material waste are achieved, overflow, aerosol pollution and artificial contact infection risks in the operation process are avoided, operation is convenient and fast, safety and reliability are achieved, and practicability is high.
Owner:JIANGSU INT TRAVEL HEALTH CARE CENT (NANJING CUSTOMS PORT OUTPATIENT DEPT)

A pig house biological safety digital monitoring method, system and medium

This invention relates to a digital monitoring method, system, and medium for biosecurity in pig houses, belonging to the field of pig house monitoring technology. The invention utilizes data statistics and key indicator calculations based on control data to generate a visual dashboard. Through spatiotemporal aggregation analysis of multi-source data on pigs, it identifies the spatial and temporal clustering of abnormal pigs and encodes multi-dimensional features to form a high-dimensional feature vector. Based on this high-dimensional feature vector, real-time risk monitoring and early warning are performed, and contact network tracing is conducted to generate tracing results. Based on the tracing results, propagation path simulation is performed to generate optimal decision-making suggestions, which are then displayed according to a preset method. This invention, through early detection and early intervention, can reduce the risk of disease spread in breeding pig farms and reduce losses such as pig deaths and production stoppages caused by epidemics. Calculations show that annual losses per farm can be reduced by 15%-30%.
Owner:WENS FOODSTUFF GROUP CO LTD