15results about How to "Experiment operation is simple" patented technology

The invention relates to a method for catalytically synthesizing 2, 4-disubstituted phthalazine 1-(2H)-ketone from 1, 5, 7-triazabicyclo [4.4. 0] dec-5-ene. According to the method, 3-alkenyl phthalide and hydrazine compounds are taken as initial raw materials, TBD which is low in price and easy to obtain is taken as a catalyst, sodium tert-butoxide is taken as alkali, reaction is carried out at room temperature, and the 2, 4-disubstituted phthalazine 1-(2H)-ketone is obtained at high yield. According to the method, the cheap TBD is adopted as the catalyst, the reaction is carried out under the room temperature condition, and compared with a traditional reaction strategy, the economic cost is greatly reduced, the steps are simple, heating and a transition metal catalyst are not needed, operation is convenient, the yield is high, the cost is low, and good economic benefits are achieved.

The application discloses a synthesis method of C3-substituted quinoxaline ketone derivatives and application thereof. A series of C3-substituted quinoxaline ketone derivatives with both terpene and quinoxaline ketone biological activity skeletons are obtained by using N-alkoxy phthalimide and quinoxaline ketone as starting substrates, under the catalysis of a photocatalyst and visible light irradiation, and at a temperature of 55-65 DEG C for 10-15 h. The application has the advantages of stable and easy-to-prepare raw materials, mild reaction conditions, simple experimental operation, good chemical selectivity and functional group tolerance, and is a green chemical synthesis method with good application prospect. The activity experiment results show that the synthesized C3-substituted quinoxaline ketone derivatives have good inhibiting effect on the growth of plant pathogenic fungi.

The utility model discloses a kind of multifunctional lithium battery thermal dynamics experimental device, belong to lithium battery thermal dynamics technical field, the device includes box, fixed frame is placed inside box, fixed frame includes fixed plate, fixed groove is equipped on fixed plate, heating assembly is placed in fixed groove, battery compartment for placing multiple lithium batteries is equipped in heating assembly, the top of heating assembly is connected with protection plate;The top and bottom of heating assembly are equipped with multiple power supply sockets and detection socket, multiple power supply columns and temperature sensing probe are separately equipped in protection plate interior, fixed groove top;Multiple grooves are sequentially equipped on the both sides of fixed groove, rotatable electrode plate is equipped in groove, the inside of electrode plate is equipped with contact block, rotate multiple electrode plate and heat assembly is clamped between multiple electrode plate, and the contact block of electrode plate is all contacted with lithium battery in heating assembly.The utility model can accurately measure multiple data, provide reliable data support for lithium battery thermal dynamics research.

The invention discloses a universal molecular beacon kit for various animal-derived components, and belongs to the technical field of molecular biological detection. Aiming at gene segments with specific structural characteristics in 11 common livestock and poultry animal genomes, the invention designs a composition of a universal primer and a molecular beacon fluorescent probe. The combination can be used for carrying out real-time fluorescent PCR detection and melting curve analysis by using the kit and the method by taking genome DNA of a sample to be detected as a template. By comparing the shape of a melting peak of a detected sample and the characteristic melting temperature (Tm value) of the detected sample, 11 animal-derived components of livestock and poultry can be quickly and accurately identified under the condition of single-tube detection. Technical innovation is achieved in the field of molecular biological detection, an efficient and reliable solution is provided for animal-derived component detection, and the method has important practical value and popularization potential.

The utility model relates to experimental apparatus technical field of ross foam appearance, concretely is a kind of ross foam appearance automation measuring device based on light intensity detection, including conventional ross foam appearance and its both end support, 15 groups wide-angle infrared opposite transmission sensor are arranged in 40mm vertical interval along support outer wall, each group of sensor contains infrared emission tube and receiving tube, arc clamp and its bolt hole and sensor recess for fixing sensor;Signal processing unit, connect sensor for converting light intensity signal into foam height data;Display unit, connect signal processing unit for real-time output measurement result;Power module, power supply for each unit.The utility model on the basis of original ross method operating procedure, through the light transmittance variation of real-time monitoring at different heights by multiple infrared opposite transmission sensors, realized the automation measurement without manual intervention, effectively avoided manual reading error and foam wall hanging interference, improved measurement accuracy and repeatability, simplified experimental operation.

The application discloses a preparation method of 2-cyano-3-hydroxy-2-buten-(4-trifluoromethyl-phenyl)amide, which comprises the following steps: reacting a compound of formula (II) with acetyl chloride or acetic anhydride under the action of a base; wherein the base comprises sodium ethoxide and / or sodium methoxide. In the application, sodium hydride with a relatively high risk coefficient is replaced by sodium alcoholate, the operation difficulty is reduced, the yield is improved compared with sodium hydride, and the application is more suitable for industrial production.

This utility model discloses a base lens holder, including a clamping rod, a fixed base, a locking plate, and a positioning device connector. One end of the clamping rod is threadedly connected to the fixed base. The locking plate is threadedly connected to the fixed base and is used to change the tightness of the holder. The fixed base is an integral structure, including a first clamping arm and a second clamping arm. The first clamping arm includes a first clamping tip, and the second clamping arm includes a second clamping tip. There is a millimeter gap between the first and second clamping arms, and the first and second clamping tips form a non-closed clamping groove. After the object to be clamped is placed in the clamping groove, it is locked by the locking plate. The clamping groove can be clamped on both sides; the upper part can clamp a microscope, and the lower part can clamp a base lens, making the connection process between the base lens and the microscope very convenient and quick.

The invention discloses a method for synthesizing a gem-difluoroolefin compound through conversion of alkane under catalysis of acridine. The gem-difluoroolefin is a multifunctional fluorine-containing synthon and is a core unit structure for improving performance in the fields of medicines, pesticides and materials. According to the method, an alpha-trifluoroolefin compound and various alkanes are taken as raw materials, and gem-difluoroallylation is directly realized under the conditions of acridine, alkali and illumination. The method has the advantages of simple preparation operation and wide substrate applicability, and contains various electron-withdrawing or electron-donating groups and various cyclic heterocyclic or non-heterocyclic alkanes. The method is mild in reaction condition, relatively high in yield and simple in subsequent treatment, and is a green chemical synthesis method with a relatively good application prospect.

This invention discloses a method for synthesizing 4,6-bis(trifluoromethyl)-1,3,5-triazabicyclo[3.1.0]hex-2-ene compounds. Using nitrile compounds and diacaridine as raw materials, the method utilizes photo-induced decomposition of diacaridine to efficiently construct the target azabicyclo skeleton. This method features mild reaction conditions and a simple synthetic route. Furthermore, it exhibits broad functional tolerance, mild reaction conditions, high yield, and simple post-processing, making it a promising green chemical synthesis method. The novel skeleton can serve as a novel bioisostere, overcoming the bottlenecks of limited existing skeleton structures and high synthetic difficulty, providing technical support for drug molecule optimization and new drug development.

The invention discloses a specific primer, a probe and a kit for rapidly identifying bulbus fritillariae cirrhosae and application of the specific primer, the probe and the kit, and aims to carry out rapid true and false identification (qualitative) and content determination (quantitative) on the bulbus fritillariae cirrhosae. The core technology is to design primers and probes capable of specifically recognizing all six bulbus fritillariae cirrhosae primordial (including bulbus fritillariae cirrhosae, unibract fritillary bulb and the like) chloroplast conserved genes specified in the 2025 edition Chinese Pharmacopoeia; meanwhile, the 16s rRNA gene is used as an internal reference, and a fluorescent quantitative PCR detection system is constructed. The method is high in specificity, common counterfeit products can be effectively distinguished, and the detection sensitivity reaches 0.005 ng / mu L. The technology provides a reliable tool for quality control of bulbus fritillariae cirrhosae medicinal materials and related preparations, and is suitable for various scenes such as market supervision, enterprise quality control, inspection and detection and the like.

The application provides a metal-doped titanium dioxide nanowire / block copolymer composite nanoparticle and a preparation method thereof, and belongs to the technical field of composite materials. The titanium dioxide nanowire is doped with metal, so that the physical and chemical properties of the titanium dioxide nanowire are improved, and the compounding capacity with the block copolymer is enhanced. In the application, a UV photopolymerization-induced self-assembly method is adopted, under the condition of UV light, macromolecular chain transfer agent of poly-4-vinylpyridine and styrene monomers are co-assembled with the metal-doped titanium dioxide nanowire in an in-situ polymerization process, so that a novel titanium dioxide nanowire / block copolymer composite nanoparticle is prepared. The application has the advantages of simple experimental operation, high yield and adjustable size of the nanomaterial, and can control the morphology of the composite nanoparticle through parameters such as UV light intensity, type of the metal-doped titanium dioxide nanowire, monomer amount and reaction time in the in-situ polymerization process in one step.

The invention discloses a microchannel-based high-resolution confocal surface-enhanced Raman rapid intermolecular interaction detection method, which does not depend on molecular markers or molecular immobilization, is based on the principle of molecular dynamic interaction diffusion, is ingeniously combined with the characteristics of microchannel microscale and high-throughput chips, and has a wide application prospect.

This invention discloses a Fe5Ni4S 8‑x O x This paper describes the preparation method and application of electrocatalysts, belonging to the fields of materials and electrocatalysis technology. The method involves first synthesizing a nickel-iron-based metal-organic framework (FeNi-MOF) via a hydrothermal method, then adding a sulfur source to hydrothermally synthesize oxygen-doped nickel pyrite (FeNi-MOF-S), and finally annealing at high temperature to generate Fe5Ni4S. 8‑x O x Electrocatalyst. Compared with the traditional high-temperature solid-state synthesis of pyrite, this method is simpler to operate and less expensive. The electrocatalyst prepared by this method has oxygen atoms directionally incorporated into the pyrite lattice, inducing changes in the electronic modes of the metal center and Ni / FeOOH lattice distortion, resulting in excellent oxygen evolution performance and significantly improved catalytic activity and stability. After being assembled into anion exchange membranes for water electrolysis, it also exhibits high activity and long-term stability. This catalyst reduces costs and energy consumption, significantly lowering costs and making it suitable for large-scale renewable energy hydrogen production, thus suitable for industrial production.

The application discloses a plant nutrient in-situ extraction and detection system and method based on microchip electrophoresis. The method first extracts nutrient ions from a plant to be detected to obtain a sample solution. The plant leaf nutrient extraction includes sampling, in-situ burning and in-situ extraction. The plant stem tissue nutrient extraction needs to include the cooperation of a capillary, a valve, a micro camera, an operation table and a micro air pressure pump. The plant rhizosphere soil nutrient extraction includes sampling, grinding, screening and extraction. Then, a control module controls a voltage module to generate a sample injection and separation high voltage, and the sample to be detected is introduced into a microchip and separated. Next, a signal module generates an excitation and reference signal, and a detection module detects the ions separated from the microchip. Different charged ions have different charge numbers, ion radii and masses, so that their migration speeds in a constant electric field are different. The ion types can be distinguished according to the time of arrival, and the concentration of the ions can be determined according to the obtained peak area.

This invention relates to a method for preparing and applying a self-supporting amorphous metal-coated nickel pyrite electrode, belonging to the field of electrocatalytic materials technology. It employs a multi-scale synthesis strategy to grow a nickel-iron metal-organic framework in situ on a nickel-iron foam substrate, followed by chemical vapor deposition (CVD). This process successfully constructs a self-supporting nickel pyrite electrode covered with an amorphous layer rich in metal clusters. This unique crystalline-amorphous integrated system forms a synergistic structure consisting of a stable conductive core, a dynamically active shell, and an interfacial strain region. The amorphous region exposes more highly active sites and serves as an ideal reconstruction precursor, thereby accelerating the formation of the active phase. Simultaneously, the crystalline core acts as a stable conductive framework, providing mechanical support and efficient electron injection for the surface active layer, kinetically limiting the reconstruction depth. This dual function prevents excessive oxidative dissolution of the catalyst, achieving a dual breakthrough in dynamic stability and catalytic performance.