861 results about "Bone material" patented technology

A biodegradable fixation element is provided for anchoring a transplant on bone. A rigid body is made of a biodegradable material, said body having an outer side and a hollow interior surrounded by a wall of said body. Numerous perforations are provided in said wall of said body for allowing growth of bone material into said interior of said body via said numerous perforations. It is proposed that the perforations are formed between said anchoring members and said perforations are formed as holes passing through said wall of said body (FIG. 1).

Methods of stabilizing the sacroiliac joint by placing an expandable device in the joint to generate laterally opposing forces against the iliac and sacral surfaces of the SI joint to securely seat the device in a plane generally parallel to the SI joint. The expandable device is coated with or otherwise contains a bone material to promote fusion of the joint. The expandable device used in methods of the present invention can be, for example, an expandable cage, a balloon, a balloon-expandable stent or a self-expanding stent.

An intervertebral disk prosthesis in a preferred embodiment has a matrix of bioincorporable fabric, and a nuclear core centrally mixed into the matrix. The core is formed by impregnating the fabric substrate centrally with a polymer, preferably of liquid form that cures into a viscoelastic solid, in which each component—polymer and fabric—reinforces the other against tearing, shearing and weakening under stress. The core is a hybrid composite adapted for elastic deformation centrally of the matrix, in which the polymer is mixed with the fabric, and is surrounded by the outer bioincorporable fabric margin of the matrix. In another embodiment, the nuclear core is separated from an outer sheath of the bioincorporable fabric by an intermediate ligament encasement that surrounds the purely polymeric core In either embodiment, each edge of the outer fabric that interfaces a vertebral end plate is impregnated with an agent to stimulate osseus incorporation and anchoring. An adjunct anchoring system with penetration of bone of adjacent vertebra may be used to for attachment until and after bioincorporation occurs.

Methods and apparatus are presented for extracting and collecting bone material from an extraction site of a patient. The method and apparatus further provides a readily accessible, and easily harvested, source of bone material without the drawbacks of current extraction methods.

A convex spinal fusion interbody space device includes spaced apart superior and inferior abutment surfaces which are effectively medially convex. The peak of such convexity is displaced anteriorly of a central plane through the device. The spacer device has front to rear lateral concave surfaces and top to bottom lateral side channels that intersect with said convex surfaces. The spacer device has a height which is greater than the width of the device. The spacer device is implanted between a pair of adjacent vertebrae by insertion in a tipped-over orientation and then reoriented to an upright orientation for engagement by facing surfaces of the vertebrae. Fusion promoting bone material is packed between the vertebrae and about the spacer device subsequent to implantation.

A system and method for anterior fixation of the spine utilizes a cylindrical implant engaged in the intradiscal space at the cephalad and caudal ends of the construct. The implants are cylindrical fusion devices (10) filled with bone material to promote bone ingrowth and fusion of the disc space. An attachment member (40) is connected to each of the fusion devices (10) and a spinal rod (50) is connected to each of the attachment members using an eyebolt assembly (53, 54, 55). In a further inventive method, a revision of the construct is achieved by removing the fusion devices. Each fusion device is engaged by an elongated guide member (62) over which a cylindrical trephine (70) is advanced. The trephine (70) is used to extract a core (84) of bone material around the fusion implant, while the guide member (62) is used to remove the bone core (84) containing the fusion implant (10). In another aspect of the invention, a removal insert (90, 90') is provided that engages an implanted fusion device (10). The removal insert (90, 90') can be used to guide the trephine (70) around the fusion device, and is connected to a removal tool (100) once the bone core is created. The removal tool (100) includes a shaft (101) attached to the removal insert (90, 90'), and a slap hammer (104) slidably mounted on the shaft.

A bone fusion implant for repair or replacement of bone includes a hollow body formed from at least two bone fragments which are configured and dimensioned for mutual engagement and which are coupled together. The hollow body may be formed of autograft, allograft, or xenograft bone tissue, and may include a core formed of at least one of bone material and bone inducing substances, with the core being disposed in the hollow body.

The invention relates to the melting coating of alcohol-base or water-base anti-penetrating sands, which uses the fireproofing bone materials, the floating agent, the felting agent, the reinforcing agent and the carrier as the preparing coating. The weight shares of the said coating are: 100,3-8,3-7,0.2-1.0 and 30-40. The invention uses chrome iron minerals as the main materials and is prior to any kinds of the traditional coating.

A system and method of bone fixation are provided for improving the bone growth and stability of the fixated bones. For example, a target site for a bone fixation procedure can be accessed at a facet of a first vertebra using a tissue dilator. Bone material can be disrupting from or at the target site, and a bone fixation device can be installed to fix the first vertebra relative to a second vertebra. The disruption and / or removal of the bone material, such as by rasping facets or a facet joint of the first vertebra and the second vertebra, can tend to promote bone growth. Further, it is contemplated that bone graft material can be inserted at the target site, such as into a joint space formed between facets of the first vertebra and the second vertebra.

Porous calcium phosphate implant compositions that approximate the chemical composition of natural bone mineral are provided. In addition to calcium phosphate, the compositions include an effervescent agent to promote the formation of interconnected pores and a cohesiveness agent to maintain the shape and hardness of the hardened composition. When introduced at an implant site, the calcium phosphate compositions are remodeled into bone. Methods for using the calcium phosphate compositions, e.g., to repair or replace bone, are also provided.

Formed compositions for application to a bone surface of a human or animal subject, comprising: a bone material; and a carrier comprising denatured demineralized bone, where the composition is formed into a shape suitable for administration to the bone. Methods are provided for making formed compositions for application to a bone surface of a human or animal subject comprise mixing a demineralized bone and water; heating the mixture to form a carrier; mixing the carrier with bone to form a moldable composition; and molding the moldable composition to produce a formed composition. Several apparatuses are provided in which to hydrate the formed bone composition. Methods of hydrating a formed bone composition are also provided.

A novel coplanar X-ray guided method and device for insertion of distal locking screws in intramedullary bone nails. The device has coplanar holes, which allow insertion of protective sleeves. Bone drill and bone screws can be inserted through the protective sleeves. Radiopaque target markers in the aiming arm enable the easy positioning of an X-ray source such that an X-ray beam is coplanar with the aiming arm transverse holes. After the X-ray source is accurately oriented, a single X-ray snapshot is enough to assess the exact distortion of the implanted intramedullary nail. The X-ray beam does not need to be coaxial with nail holes anymore. The aiming arm has a mobile portion and a fixed portion fastened to the nail, wherein said aiming arm can be adjusted, displacing the mobile portion over the fixed portion, to compensate for the distortion of the intramedullary nail after implanted. Once the aiming arm is precisely positioned, the aiming arm transverse holes and intramedullary nail holes are accurately aligned, protective sleeves are inserted through aiming arm holes, bone drills are drilled through the intramedullary nail holes and surrounding bone material, and bone screws are screwed, locking the intramedullary nail to the bone.

The invention relates to a spinal implant consisting of a bone material body which is embodied in a curved manner in its longitudinal direction and is provided with coupling means.

A minimally invasive interbody device assembly that includes an interbody device that restores the disc space height between two vertebrae and an instrument detachably coupled to the interbody device for positioning the device in the disc space and delivering bone material to the disc space that is distributed on both sides of the interbody device. The device is inserted into the disc space using the instrument in a direction so that the wide dimension of the device is substantially parallel to the body of the vertebrae. The device is then rotated by the instrument so that the wide dimension of the device becomes perpendicular to the vertebral body so as to cause the disc space height to be restored. Bone graft material is then forced down the instrument so that the bone graft material is distributed on both sides of the device. The instrument is then detached from the device.

A collection device for collecting bone material during a spinal fusion surgical procedure so that the bone material can later be used as a graft material for the fusion procedure. The device includes a container that collects the bone and other material that is removed from the patient during the surgical procedure through a suction hose. The device includes a plunger having a filter plate sealed to the inside of the container. The plunger is pushed down into the collected material in the container so that blood and other liquids are forced through the plate to be separated from the bone material. A cover at the bottom of the container can be removed to remove the collected bone material.

Disclosed are apparatuses and methods for delivering implants through a posterior aspect of a vertebral body such as a pedicle and placing the implant or performing a procedure into the anterior aspect of the vertebral body. A representative apparatus includes an outer cannula, and advancer tube and a drill assembly. It is envisioned that at least one of the outer cannula, the advancer tube or the drill assembly can be viewed in vivo using for example, a CT scan or fluoroscope. The present invention is also directed to an apparatus for forming an arcuate channel in bone material. The apparatus includes and advancer tube and a drill assembly.

Osteogenic bone implant compositions that approximate the chemical composition of natural bone are provided. The organic component of these implant compositions is osteoinductive despite the presence of the inorganic component and, further, is present in an amount sufficient to maximize the regenerative capabilities of the implant without compromising its formability and mechanical strength. The composition may be an osteoinductive powder, including demineralized bone matrix (DBM) particles, a calcium phosphate powder, and, optionally, a biocompatible cohesiveness agent. The powder may be combined with a physiologically-acceptable fluid to produce a formable, osteoinductive paste that self-hardens to form a poorly crystalline apatitic (PCA) calcium phosphate having significant compressive strength. The bone implant materials retain their cohesiveness when introduced at an implant site and are remodeled into bone in vivo. Methods for using these implant materials to repair damaged bone and a method of assaying the content of DBM particles, by weight, in a bone implant material are also provided.

A textured bone graft or implant device includes a spatial member having a number of three dimensional units coupled together, the three dimensional units each include a number of bars coupled together to form a number of openings and to form a porous structure for the spatial member and for allowing the bone materials of the user to be grown and filled into the openings of the textured implant device, the spatial member includes a chamber for engaging with a casing, and the casing includes a compartment for engaging with an inner core, the casing and the inner core each include a number of bars for forming a resilient or flexible or compressible or deformable structure.

A convex spinal fusion interbody space device includes spaced apart superior and inferior abutment surfaces which are effectively medially convex. The peak of such convexity is displaced anteriorly of a central plane through the device. The spacer device has a height which is greater than the width of the device. The spacer device is implanted between a pair of adjacent vertebrae by insertion in a tipped-over orientation and then reoriented to an upright orientation for engagement by facing surfaces of the vertebrae. Fusion promoting bone material is packed between the vertebrae and about and within the spacer device subsequent to implantation.

Ceramic materials operable to repair a defect in bone of a human or animal subject comprising a porous ceramic scaffold having a bioresorbable coating, and a carrier comprising denatured demineralized bone. The ceramic may contain a material selected from the group consisting of hydroxyapatite, tricalcium phosphate, calcium phosphates, calcium carbonates, calcium sulfates, and combinations thereof. The compositions may also contain a bone material selected from the group consisting of: bone powder, bone chips, bone shavings, and combinations thereof. The bioresorbable coating may be, for example, demineralized bone matrix, gelatin, collagen, hyaluronic acid, chitosan, polyglycolic acid, polylactic acid, polypropylenefumarate, polyethylene glycol, or mixtures thereof.

The invention relates to a vertebral column implant for intercorporal fusion on the vertebral column, consisting of a body which consists of bone material and which is curved in the direction in which it extends longitudinally. The size of the implant is adapted to the intermediate vertebral space available between adjacent vertebrae after the intermediate vertebral body has been removed.

An attachment surface for an implantable device has an irregular pattern formed through a process including masking, chemical or electrochemical etching, blasting and debris removal steps. Surface material is removed from the implant surface without stress on the adjoining material and the process provides fully dimensional fillet radii at the base of the surface irregularities. This irregular surface is adapted to receive the ingrowth of bone material and to provide a strong anchor for that bone material which is resistant to cracking or breaking. The surface is prepared through an etching process which utilizes the random application of a maskant and subsequent etching in areas unprotected by the maskant. This chemical etching process is repeated a number of times as necessitated by the nature of the irregularities required in the surface. The blasting and debris removal steps produce microfeatures on the surface that enhance the ingrowth of bone material.

The present invention is directed to methods and compositions for manufacturing a bone graft substitute. A powder compaction process is utilized to generate a shaped product comprised of a bone material and in some embodiments a processing aid is utilized to facilitate compaction of the bone material and / or for release of the product from the die. In one aspect of the present invention, the manufacturing process comprises a withdrawal press having a shelf die, a lower punch, and an upper punch, wherein at least both the shelf die and lower punch are configured to impart at least part of the shape of the particle upon the material.

Methods of stabilizing the sacroiliac joint by placing an expandable device in the joint to generate laterally opposing forces against the iliac and sacral surfaces of the SI joint to securely seat the device in a plane generally parallel to the SI joint. The expandable device is coated with or otherwise contains a bone material to promote fusion of the joint. The expandable device used in methods of the present invention can be, for example, an expandable cage, a balloon, a balloon-expandable stent or a self-expanding stent.

The invention relates to a method for preparing superfine fiber bone materials of an electrodeposition calcium phosphate mineralized layer, which comprises the following steps: firstly, high-polymer superfine fibers are prepared on the surface of a metal electrode by adoption of electrostatic spinning and taken as an electrochemical deposition template; a layer of bone salt ingredients which are rich in calcium and phosphor is deposited on the surface of the fibers by the constant-voltage or constant-current deposition technology; mineralized superfine fibers are soaked into 0.1 to 1.0 mol per liter of NaOH solution for 1 to 24 hours; mineralized electro spinning fibers are subjected to die stamping into blocks under the pressure of between 10 and 40 MPa; and the porous bone materials with a porosity between 50 and 90 percent and a pore diameter between 50 and 500 micrometers are processed by the salt particle leaching / gas foaming technology, and are used for bone defect restoration after freeze-drying sterilization. The porous bone materials prepared by the method have better biocompatibility; and the electrochemical deposition technology can prepare organic-inorganic composite materials with higher bone salt content within a shorter period; and the preparation time is short and the preparation conditions are mild.

The present invention addresses the processing of waste and low-value products that contain bone material to produce useful materials in reliable purities and compositions, at acceptable cost, and with high energy efficiency. In particular, the invention comprises a process that converts various feedstocks such as offal, animal manures, and municipal sewage sludge, to useful materials including gas, oil, specialty chemicals, and carbon solids. The process heats the feedstock in order to breakdown proteins and separate organic material from bone material, applies further heat and pressure to the resulting liquid mixture, separates out various components, then further applies heat and pressure to one or more of those components. The invention further comprises an apparatus for performing a process of converting waste products into useful materials, and an oil product that arises from the process.

This invention relates to arthodesis for stabilizing the spine. More specifically, the present invention is directed to an intervertebral spacer formed of a bone material and to methods of treating patients having spinal deformities. The invention provides a spinal implant assembly comprising bone-derived components. The bone-derived components can be formed into modular units that can be assembled to provide a wide variety of implant configurations. In addition, the bone-derived components can form scaffold that can withstand the shear and impact forces necessary to insert the assembled implant into a disc space between adjacent vertebrae. In preferred forms the implants define an open spacer that serves as a depot for receipt of an osteoconductive material. The ostoegenic material is preferably a moldable filler that can form a molded reinforced implant.