286 results about "Electro spinning" patented technology

The invention belongs to the technical field of medical dressings for repairing skin injury wounds, and provides a nanofiber wound dressing with a photo-thermal chemical synergistic antibacterial effect and a preparation method. A PVA / CS solution composed of polyvinyl alcohol PVA and chitosan CS is used as an electrospinning matrix, branched polyethyleneimine BPEI modified graphene oxide GO nanoparticles GO-BPEI are added to serve as a photo-thermal antibacterial component, lanthanum chloride is added to serve as a chemical antibacterial component, an electrostatic spinning solution is prepared, the electrostatic spinning solution is subjected to electrostatic spinning, and the PVA / CS / GO-BPEI / La nanofiber wound dressing is obtained. The obtained fiber surface has a good three-dimensional structure, shows obvious chemical antibacterial ability, can be subjected to photothermal conversion under near-infrared light illumination, can achieve the purpose of photothermal bacteriostasis, further improves the antibacterial property, and has good mechanical property, air permeability, water absorption and biocompatibility at the same time.

The invention discloses an electrostatic spinning preparation method of a multifunctional composite nanofiber membrane, which comprises the following steps: step 1, sequentially adding PVDF (Polyvinylidene Fluoride) and PLA (Polylactic Acid) into a first mixed solvent, and adding TiO2 while stirring to obtain a shell solution; melting n-octadecane to obtain a core layer solution; step 2, adding PVDF into a second mixed solvent to obtain a PVDF electrospinning solution; 3, the shell layer solution and the core layer solution are subjected to coaxial electrostatic spinning to form core-shell fibers, the PVDF electrospinning solution is subjected to single-shaft electrostatic spinning to form PVDF beads, high voltage is provided, and PVDFamp formed by compounding the core-shell fibers and the PVDF beads is formed on the aluminum foil; the invention relates to a PVDF / PLA / TiO2 (at) Oct composite nanofiber membrane. The material has good anti-ultraviolet, waterproof, breathable, self-cleaning and thermal regulation functions, and has excellent mechanical properties and degradability.

Aspects of the disclosure relate to synthetic tissue or organ scaffolds and methods and compositions for promoting or maintaining their structural integrity. Aspects of the disclosure are useful to prevent scaffold damage (e.g., delamination) during or after implantation into a host. Aspects of the disclosure are useful to stabilize tissue or organ scaffolds that include electrospun fibers.

The invention relates to the field of textile fabrics, and particularly discloses an antibacterial and crease-resistant garment fabric and a preparation process thereof. The antibacterial and crease-resistant garment fabric is prepared from modified cotton fibers and electrospun fibers of polyacrylonitrile and polyurethane according to the mass ratio of 1: (0.1-0.3): (0.3-0.5), and a preparation method of the polylactic acid fiber modified cotton fibers containing silver nanowires comprises the following steps that the cotton fibers are padded in finishing liquid and then dried and shaped, and pretreated cotton fibers are prepared; the pretreated cotton fibers are padded in the treating fluid and then dried and baked, and modified cotton fibers are prepared; the finishing liquid is prepared from the following raw materials: citric acid modified titanium dioxide sol, sodium hypophosphite, triethanolamine and deionized water; the treating fluid is prepared from the following raw materials: nylon waste silk, chitosan quaternary ammonium salt, N, N-dimethylformamide and alkaline silica sol. The garment fabric has the advantages of being good in antibacterial and crease-resistant effect, lasting in antibacterial effect and high in breaking strength.

The invention discloses a three-fluid three-dimensional flow guide spinning head, electrostatic spinning equipment and a batch preparation method of three-chamber embedded parallel structure nanofibers, three different fluids are synchronously guided into a high-voltage electrostatic field by simultaneously arranging a plurality of nozzle outlets with combined structures, and a plurality of complex combined nozzle outlets are used as macroscopic templates, so that the three-chamber embedded parallel structure nanofibers are prepared under the high-voltage electrostatic field. Through interaction of a high-voltage electrostatic field and fluids, batch preparation of the three-chamber embedded and column-structured nanofibers by multi-fluid common electrospinning is realized. The three spinning solutions are guided to a common outlet through the first series of metal capillary tubes, the second series of metal capillary tubes and the spinning solution insulating container respectively; the first series of metal capillary tubes and the second series of metal capillary tubes are respectively dispersed from respective capillary tube gathering inlets, penetrate through the interior of the spinning solution insulating container to the bottom of the spinning solution insulating container and vertically penetrate out to form a plurality of outlets which are parallel in pairs; a through hole outlet is formed in any parallel outlet at the bottom of the spinning solution insulating container to form a common outlet of the three spinning solutions, and the three-chamber embedded and arrayed nano structure is directly prepared in batches in a single step.

A three-dimensional electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The three-dimensional electrospun nanofiber scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is coupled to the first layer using a coupling process and includes a plurality of varying densities formed by the second plurality of electrospun polymeric fibers. The first and second layers are configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The three-dimensional electrospun nanofiber scaffold is configured to be applied to the tissue substrate containing the defect.

Disclosed herein are non-woven graft materials for use in specialized surgical procedures involving nerve repair and regeneration. Some embodiments describe electrospun fiber products such as conduits, wraps, or grafts comprising a resorbable hybrid-scale matrix to facilitate nerve repair and regeneration.

The invention relates to the technical field of medical instruments, in particular to a multi-layer ultra-light hernia patch which comprises a large-mesh electrostatic spinning tissue ingrowth layer, a mesh woven base material layer and an anti-adhesion layer which are sequentially connected in a stacked mode. Wherein after the large-mesh electrostatic spinning tissue ingrowth layer is implanted into a human body, a cell microenvironment can be better simulated, cell adhesion, differentiation and migration are facilitated, uniform distribution of newborn cells in the fiber direction of an electrospinning membrane is promoted, granulation tissues uniformly ingrow in a defect part, and the electrospinning fiber membrane and the tissues are cooperatively repaired; secondly, the middle layer can provide supporting performance and mechanical performance of the patch in the early stage for the patch, the defects of the electrospinning fiber membrane in the supporting performance and the mechanical performance are overcome, the long-term implantation amount of the patch after later degradation is greatly reduced, and the foreign body sensation is obviously reduced; the anti-adhesion layer also adopts the electrostatic spinning technology, and the anti-adhesion effect is achieved by selecting materials and regulating and controlling the porosity, the aperture and the fiber diameter of the electrospun fiber membrane.

The present invention discloses a method for preparing a separation-catalysis structured ultrafiltration membrane using electrospun nanofibers as a substrate. The method uses a nanofiber membrane doped with nanoparticles prepared by electrospinning as a substrate, synthesizes an ultrafiltration membrane thereon by a non-solvent induced phase separation method, and obtains a multifunctional membrane with a separation-catalysis spatial order. The membrane successfully integrates separation and catalysis into a functionalized molecular sieve membrane, which not only maintains the original high flux and high retention of the ultrafiltration membrane, but also can select suitable nanomaterial electrospun nanofibers as a base catalytic layer according to different pollutants, thereby achieving efficient degradation of pollutants. The removal of multi-component pollutants mainly depends on the orderly arrangement of separation and catalysis. Membrane separation removes macromolecular substances such as natural organic matter that affect the advanced oxidation process before catalysis, thereby improving the degradation performance of the catalytic layer for small molecules; at the same time, the confinement effect of the spinning fiber on the catalyst effectively solves the problem of nanoparticle loss.

The invention provides a hot airflow-assisted electrospinning method for improving the yield of nanofibers, which comprises the following steps: dissolving a high-molecular polymer in a solvent to prepare a spinning solution; and carrying out electrostatic spinning on the spinning solution to a collection substrate by utilizing a hot air flow auxiliary electrospinning device to obtain the nanofiber. According to the method, the volatilization speed of solvents (including water systems and non-water systems) in the spinning process is remarkably increased, the problem that spinning is difficult to conduct through a spinning solution with the low solvent volatilization speed is solved, and the water-based spinning solution with the high-molecular polymer concentration as low as 1 wt% can be electrospun; spinning jet flow is further stretched and split through hot air flow, fibers with smaller diameters are formed and deposited on a collecting substrate, the yield is increased, meanwhile, the specific surface area of the nanofibers is increased, functional substances are saved, the functional effect of the nanofibers is improved, and the yield of the prepared nanofibers can reach 10 g / h; and the problem that the needle head is blocked when a solvent near the needle head is promoted to volatilize by heating is avoided.

The invention relates to the technical field of bioengineering, in particular to a manufacturing method of a flexible suspended microelectrode array device, which comprises the following steps of: manufacturing a device frame with a culture tank, printing a suspended ordered carrier fiber array above the culture tank through a suspended melting electrospinning process, and carrying out metal layer patterning sputtering on an electrode on carrier fiber to obtain the flexible suspended microelectrode array device. Then forming a patterned insulating layer on the surface of the metal layer by using an electrostatic spraying mode, and finally integrating an electrostatic spinning ordered fiber scaffold as a cell culture scaffold. The prepared suspended and flexible microelectrode array device can ensure the attachment of the electrode and the cell for a long time in the cell in-vitro culture process, and realizes the long-term detection of a field potential signal. The manufacturing method does not need sacrifice materials, the preparation process is simple and efficient, the cost is reduced, and wide application prospects are achieved.

The invention provides a method for preparing nanofiber doped with a large-particle antibacterial agent by a needleless electrostatic spinning device. The method comprises the following steps: adding a high-molecular polymer and a large-particle antibacterial substance into an organic solvent to prepare a spinning solution; electrospinning nanofibers doped with a large-particle antibacterial agent on the surface of the fabric through a needleless electrostatic spinning device; the needleless electrostatic spinning device comprises an electrode wire, a liquid brushing tank, a direct-current high-voltage power supply, a winding roller, a metal plate, a liquid storage bottle and a movable spraying brush. The electrode wire is used for replacing a needle type electrode, production efficiency is improved, and needle blockage is avoided; the liquid storage bottle reduces volatilization of the spinning liquid, the spinning liquid is continuously stirred and pumped to the liquid brushing tank to be brushed on the electrode wires, the antibacterial agent is prevented from being deposited, and the antibacterial agent is evenly distributed on the nanofibers; an air injection brush head is installed to prevent large particles from depositing on the electrode wires; according to the method, the selection limitation on the high-molecular polymer and the antibacterial agent is small, and the prepared antibacterial fabric has lasting antibacterial property.

The invention discloses a press-fit preparation method of a high-thermal-conductivity circuit board and the high-thermal-conductivity circuit board, and the preparation method comprises the steps: carrying out the dispersion and solidification of a liquid metal gallium-indium alloy and fiber mixture in an inert argon atmosphere, and fusing with a substrate, and obtaining a self-adaptive heat-conduction substrate; carrying out gradient deposition and etching treatment on the self-adaptive heat conduction base material to obtain a gradient spacing template; carrying out electrospinning infiltration and heat treatment on the gradient spacing template to obtain a base material containing a dynamic heat-conducting network; conducting layer pre-pressing treatment is conducted on the base material containing the dynamic heat conduction network, and a pre-assembled plate is obtained; performing staged dynamic pressing treatment on the pre-assembled board to obtain a molded circuit board; and performing surface spraying and deposition treatment on the molded circuit board to obtain the high-thermal-conductivity circuit board. The problems of poor heat flow path, poor interface bonding performance and the like in the prior art are solved, the heat management effect is remarkably improved, and the reliability and performance of an electronic product are remarkably improved.

The novel flexible electrodes disclosed herein utilize the low bending stiffness of electrospun nanofiber mats to achieve the material properties required for surgical implantation and sustained bidirectional communication with peripheral nerves without compromising electronic functionality. According to certain embodiments disclosed herein, implantable neural electrode probes are provided which comprise a polymeric substrate having proximal and distal ends, an electrode interface at the proximal end of the substrate; at least one neural contact at the distal end of the substrate; and electrically conductive traces formed on the fibrous substrate providing electrical communication between the at least one neural contact and the electrode interface, wherein the substrate comprises a nonwoven mass of polymeric nanofibers.

According to the invention, the electrospun nanofiber membrane is used as a substrate to attach a conductive material MXene, so that the piezoresistive sensing function and the attached performance of the nanofiber membrane are obtained at the same time. A complete fiber-based stress-strain sensor is constructed by taking nylon yarns as an inner core, a nanofiber membrane as an adhesion substrate and an additional functional layer, MXene as a conductive layer and PDMS as a protective layer.

The invention belongs to the technical field of flexible electronic materials and sensing, and particularly relates to a PVDF (polyvinylidene fluoride) fiber membrane doped with a surface modified boron nitride nano material and a preparation method of the PVDF fiber membrane. The PVDF fiber membrane is prepared by adopting an electrostatic spinning method, and a surface-modified boron nitride (BN) nano material is doped during spinning, so that the electrospun PVDF / BN composite fiber membrane is prepared. The piezoelectric property of the electrospun PVDF fiber membrane can be effectively improved by adding the boron nitride, the dispersity of the boron nitride nano material in PVDF can be improved after the boron nitride nano material is subjected to surface modification, and the piezoelectric property of the composite fiber membrane is further enhanced. The electrospinning PVDF / BN flexible piezoelectric fiber membrane provided by the invention can be widely applied to the fields of human health monitoring, intelligent wearable equipment, biomedical treatment and the like.

The invention provides an electrospinning in-situ synthesized NH2-MOF multifunctional air purification nano-fiber membrane and a preparation method thereof. The method comprises the following steps: S1, preparing a polylactic acid solution; s2, preparing electrospun polylactic acid fibers; s3, preparing an MOF synthesis precursor solution; and S4, preparation of the NH2-MOF multifunctional nano-fiber membrane: soaking the electrospun polylactic acid fiber membrane obtained in the S1 into the MOF synthesis precursor solution prepared in the S3, performing constant-temperature synthesis in microwave and ultrasonic environments, washing with deionized water after synthesis is finished, and standing and drying to obtain the NH2-MOF multifunctional nano-fiber membrane. The prepared NH2-MOF multifunctional nano-fiber membrane has the advantages of being large in specific surface area, high in filtering performance, low in air resistance, high in carbon sequestration capacity and the like, and the application prospect of a polylactic acid fiber material in the fields of air filtering and carbon sequestration is tamped.

The invention discloses a multifunctional composite flexible fabric which has multiple functions of radiation refrigeration, energy collection, hydrophobicity and antibiosis. The composite flexible fabric is composed of a plurality of electrostatic spinning fiber layers, and all the layers are formed through electrostatic spinning in sequence from top to bottom. Comprising at least two polymer electrospinning fiber layers and at least one nanometer functional electrospinning fiber layer, the nanometer functional electrospinning fiber layer is a middle interlayer, and the nanometer functional electrospinning fiber layer and the polymer electrospinning fiber layers located on the upper surface and the lower surface respectively form a sandwich structure. The invention also discloses a preparation method of the flexible fabric, and the flexible fabric is prepared by electrostatic spinning of PVDF or a series of polymer solutions thereof and a polymer solution modified by adding functional nanoparticles by using an electrostatic spinning method. The preparation method can effectively regulate and control the form of the nanofiber and the functions of the nanoparticles, so that the functional scattering nanoparticles and the nanofiber generate a synergistic effect, and the functional fabric with thermal management, energy collection and antibacterial properties is integrated.

This invention discloses a multifunctional composite flexible fabric with multiple functions including radiative cooling, energy harvesting, hydrophobicity, and antibacterial properties. The composite flexible fabric consists of several electrospun fiber layers, each formed sequentially by electrospinning in a top-to-bottom order. It includes at least two polymer electrospun fiber layers and at least one nanofunctional electrospun fiber layer, wherein the nanofunctional electrospun fiber layer serves as an intermediate sandwich layer, forming a sandwich structure with the polymer electrospun fiber layers located on the upper and lower surfaces. This invention also discloses a method for preparing this flexible fabric, using electrospinning to prepare it by electrospinning a PVDF or related polymer solution and a polymer solution modified with functional nanoparticles. This preparation method can effectively control the morphology of the nanofibers and the functions of the nanoparticles, enabling a synergistic effect between the functional nano-scattering particles and the nanofibers, resulting in an integrated functional fabric with thermal management, energy harvesting, and antibacterial properties.

A three-dimensional electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The three-dimensional electrospun nanofiber scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is coupled to the first layer using a coupling process and includes a plurality of varying densities formed by the second plurality of electrospun polymeric fibers. The first and second layers are configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The three-dimensional electrospun nanofiber scaffold is configured to be applied to the tissue substrate containing the defect.

The invention discloses a method for constructing a high-activity gradient porous carbon nanofiber electrode material based on graphite microparticles and application of the high-activity gradient porous carbon nanofiber electrode material in a vanadium battery. The method comprises the following steps: dispersing graphite microparticle powder with different masses into a mixed solution of PAN and DMF to prepare three electrospinning precursor solutions with different graphite powder contents; and carrying out continuous electrostatic spinning on the three electrospinning precursor solutions according to the size sequence of the content of the graphite powder by using an electrostatic spinning technology to obtain an original gradient structure composite fiber material, flattening the original gradient structure composite fiber material by using a corundum plate, and carrying out pre-oxidation and carbonization treatment in a tubular furnace to obtain the high-activity gradient porous carbon nanofiber electrode material. The surface containing more graphite particles in the material is in contact with a current collector, the surface containing less graphite particles is in contact with a diaphragm, and an all-vanadium redox flow battery is assembled, so that the mass transfer of an electrolyte in an electrode can be promoted while the electrochemical reaction activity of vanadium ions is improved, and the battery performance is further effectively improved.

The invention discloses a preparation method and application of an electrospun nanofiber membrane-based flexible SERS (Surface Enhanced Raman Scattering) substrate, and belongs to the field of preparation of SERS substrates. The preparation method comprises the following steps: firstly, preparing a polymer nanofiber membrane by adopting an electrostatic spinning method, and then depositing noble metal nanoparticles on the surface of the electrospinning polymer nanofiber membrane by adopting a magnetron sputtering technology, so as to obtain the noble metal nanoparticle and polymer nanofiber membrane flexible SERS (Surface Enhanced Raman Scattering) substrate. According to the present invention, the problems that the SERS substrate cannot be accurately controlled and cannot be continuously produced are solved, the preparation method has advantages of simpleness, high efficiency, no pollution, low cost and large-scale manufacturing compared with the existing preparation method, the substrate has characteristics of large specific surface area, high density hot spot distribution, good stability and adjustable size structure, and the trace detection of the pesticide residue on the irregular surface can be achieved.

Polyacrylonitrile (PAN)-based gel polymer electrolyte (GPE) membrane separators for lithium-sulfur batteries. The PAN-based GPE membrane separators may include a freestanding electrospun nonwoven mat of PAN-based nanofibers. The PAN-based GPE membrane separators may include one or more inorganic nanoparticles dispersed therein. A lithium-sulfur battery including a freestanding PAN-based GPE membrane separator may be characterized by an electrolyte to sulfur (E / S) ratio of less than 4 µL / mg and a ratio of an areal capacity of the anode to that of the cathode (N / P ratio) of less than 2. A thickness of an example PAN-based GPE membrane separator may be less than 30 µm.

The invention discloses a single-layer Janus fiber membrane with pore and wettability double gradients and a one-step electrospinning preparation method of the single-layer Janus fiber membrane, and belongs to the technical field of electrostatic spinning functional fiber materials. According to the method disclosed by the invention, polyacrylonitrile (PAN) has weak hydrophilicity, and hydrophobic modification and hydrophilic modification of the PAN fiber membrane can be realized by respectively adding fluorinated titanium dioxide (F-TiO2) particles and tannic acid (TA); gradient regulation and control of pores are realized by regulating and controlling the concentration of the PAN spinning solution. The method comprises the following steps: S1, mixing F-TiO2 particles with PAN to obtain a spinning solution A; s2, mixing TA and PAN to obtain a spinning solution B; s3, the spinning solution A and the spinning solution B are sequentially sucked into the same injector, and a pre-spinning solution C is obtained; and S4, preparing the single-layer fiber membrane through electrostatic spinning. The fiber membrane has a pore / wettability double-gradient structure, shows excellent one-way moisture conduction performance, and has wide application prospects in the fields of personal protection masks, outdoor sportswear and the like.

A method for controlling fiber cross-alignment in a nanofiber membrane, comprising: providing a multiple segment collector in an electrospinning device including a first and second segment electrically isolated from an intermediate segment positioned between the first and second segment, collectively presenting a cylindrical structure, rotating the cylindrical structure around a longitudinal axis proximate to an electrically charged fiber emitter; electrically grounding or charging edge conductors circumferentially resident on the first and second segment, maintaining intermediate collector electrically neutral; dispensing electrospun fiber toward the collector, the fiber attaching to edge conductors and spanning the separation space between edge conductors; attracting electrospun fiber attached to the edge conductors to the surface of the cylindrical structure, forming a first fiber layer; increasing or decreasing rotation speed of the cylindrical structure to alter the angular cross-alignment relationship between aligned nanofibers in adjacent layers, the rotation speed being altered to achieve a target relational angle.

The invention discloses a degradable electrospinning dressing, and belongs to the technical field of biological materials.The degradable electrospinning dressing is prepared by dispersing aminosilane modified FeO in a chitosan solution, adding a gelatin solution, stirring and mixing evenly, conducting gradient freezing under the action of a rotating magnetic field, conducting permeation with a PLGA solution, then conducting electrospinning, conducting crosslinking with a genipin solution, conducting washing and conducting drying. And sterilizing to obtain the degradable electrospinning dressing. According to the degradable electrospinning dressing prepared by the preparation method disclosed by the invention, an electrospinning auxiliary material is obtained through three-layer gradient electrospinning by modifying a Fe3O4 enhanced chitosan-gelatin composite base material with amino silane and combining magnetic field assistance and gradient freezing forming, a bionic fiber structure is constructed, wound exudation dynamic balance and long-acting antibiosis are realized, the optimal moisture balance of a wound part is kept, and the antibacterial property of the wound part is improved. And wound healing is effectively promoted.

The invention provides a laser-electric coupling Taylor cone bionic electrospinning process method, a folded conductive metamaterial and application, the preparation method comprises the following steps: dissolving a carbon nanotube in N, N-dimethylformamide, stirring and carrying out ultrasonic treatment, then adding polymer powder, and continuously stirring to obtain a precursor solution; in the first stage, electrostatic spinning is carried out, meanwhile, a laser beam with the wavelength of 589-650 nm is focused on a rotating Taylor cone for electrostatic spinning, the treated spinning film is heated in air, heat preservation is carried out, then the temperature is reduced to the room temperature, and in the first stage, heating is carried out firstly, and then heat preservation is carried out; then raising the temperature in the second stage, keeping the temperature, and finally cooling to room temperature; in the coupled field spinning process, the synergistic effect of arrangement of the carbon nanotubes and the carbon nanofibers induced by photo-thermal response, local fluidity enhancement and an electric field jointly promotes axial dispersion and slidable in the fibers and formation of a self-adaptive network; and the folded conductive metamaterial capable of being folded for 10 million times is successfully prepared.

The present invention relates to a non-woven filter media (100, 200) comprising: - a first melt-blown layer (102, 202) comprising fibers made from a polymer material, wherein the polymer material comprises a thermoplastic resin and at least one of a charge adjuvant and a nucleating agent; - a second layer (104, 204); and - a third layer (106, 206) arranged between the first layer and the second layer, the third layer being made of electrospun nanofibers. The present invention also relates to a filter element comprising this filter media and to a bag filter for a heating, ventilation and air conditioning system, where the bag filter comprises the filter media or the filter element.

Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed to yield a stabilizing effect without altering morphological properties of a first fiber system. By addition of a stabilizing fiber population one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state. In one particular abstract, medical barrier materials may be formed from the electrospun materials to provide improved medical barriers for treatments.

The application belongs to the field of functional material preparation, and particularly relates to a preparation method of a super-light high-nucleic-acid-absorption electrospun fiber sponge material and application thereof. The SiO2 electrospun fiber is used as a framework, a three-dimensional monolithic structure assembled by fragmented electrospun nanofiber membranes is used, the interconnected nanofiber cell structures of which endow the three-dimensional monolithic structure with high porosity and excellent structural flexibility and stability. Meanwhile, the amino-rich polyethylene imine and chitosan are chemically crosslinked by using epichlorohydrin as a crosslinking agent, and finally during freeze-drying, the ice crystals are partially sublimated, leaving a pore structure, and a porous sponge material is obtained. The material has a high nucleic acid adsorption capacity, and makes nucleic acid extraction more simple, rapid and sensitive.