The multi-matrix PFAS detection method comprises the following steps: mixing
WAX and an HLB (
Hydrophile-Lipophile Balance) adsorbent, and then adding a cross-linking agent, an initiator and a catalyst for
polymerization reaction to prepare an adsorption glue solution; and filling the adsorption glue solution into a
pipe seam between the sampling
pipe and the auxiliary
pipe, and forming, soaking and
cutting to complete the preparation of the annular adsorption phase. Adding an
internal standard into a to-be-detected sample, diluting the to-be-detected
human body sample with
ultrapure water, and not diluting the to-be-detected
sewage sample; a to-be-detected sample PFAS is enriched by using a sampling tube containing an annular adsorption phase, and a to-be-detected solution is obtained through
elution,
nitrogen blowing, redissolution and
filtration. The
WAX adsorbent and the HLB adsorbent are combined with the cross-linking agent, so that the contact area and the adsorption efficiency of the adsorption material to PFAS are improved, and the adsorption material is suitable for multiple matrixes such as serum,
urine and
sewage;
sample dilution can reduce
protein interference and simplify pretreatment steps; by combining the
high performance liquid chromatography-
tandem mass spectrometry, the PFAS component and content of the sample can be accurately detected, the materials are easy to obtain, and the cost is low.