153 results about "Adduct" patented technology

The invention discloses a method for synthesizing a dichloroacetyl compound, which comprises the following steps: tetrachloroethylene and an acid are subjected to an addition reaction at 100-200 DEG C to obtain an adduct, then the adduct is subjected to an acidolysis, hydrolysis or alcoholysis reaction to obtain the dichloroacetyl compound, the acid for the addition reaction is at least one of sulfuric acid, trifluoromethanesulfonic acid, methanesulfonic acid and phosphoric acid, and the acid for the alcoholysis reaction is at least one of sulfuric acid, trifluoromethanesulfonic acid, methanesulfonic acid and phosphoric acid. The molar ratio of the tetrachloroethylene to the acid is 1: (1-10). By controlling the types of acids and increasing the temperature of the addition reaction, the addition reaction of tetrachloroethylene and acids in the absence of a catalyst is realized. Double bonds of tetrachloroethylene and hydrogen protons are subjected to an addition reaction in a strong acid environment to form a cationic intermediate, then the cationic intermediate is combined with acid radical anions to form an adduct, and the adduct intermediate is high in activity, unstable and free of separation and can be directly subjected to a hydrolysis reaction, an acidolysis reaction or an alcoholysis reaction with another substrate (such as water, acid or alcohol) respectively. The synthesis of dichloroacetyl series compounds is realized, and the route has universality and diversity.

To provide a defoaming agent capable of exhibiting excellent defoaming properties (foam breaking and foam suppressing effects) and excellent surface finishing properties (cissing and foam breaking marks).SOLUTION: And at least one hydrophobic substance (C) selected from the group consisting of hydrophobic silica, fatty acid metal salts, fatty acid amides, and waxes, wherein the content of the liquid glycerin fatty acid ester (A) is 4 to 49% by weight, the content of the liquid alkylene oxide adduct (B) is 51 to 96% by weight, and the content of the hydrophobic substance (C) is 0.1 to 15% by weight, based on the weight of the liquid glycerin fatty acid ester (A) and the liquid alkylene oxide adduct (B).SELECTED DRAWING: None

A method of making paper and paperboard products, including absorbent structures, where the method includes mixing ultra-high molecular weight (“UHMW”) glyoxalated polyvinylamide (“GPVM”) adducts and high molecular weight (“HMW”) anionic polyacrylamide (“APAM”) with the furnish during stock preparation of a wet laid papermaking process.

The invention relates to the technical field of organic silicon catalysis, and discloses a hydrosilylation reaction catalyst and a preparation method thereof, the catalyst is prepared from a platinum complex catalyst solution, maleic anhydride, triphenyl borate, tetraethoxysilane, propylene carbonate and diethylene glycol dibutyl ether; the preparation method comprises the steps of solvent water removal, electronic relay adduct preassembly, active metal introduction, thermal induction aging and the like. An electron-deficient coordination center is constructed through a step-by-step process, the electron cloud density of the platinum center is reduced by utilizing the Lewis acid characteristic of triphenyl borate, and the solvent cage effect of propylene carbonate is matched, so that the high-temperature tolerance of the catalyst is improved, and the generation of platinum black is effectively inhibited; meanwhile, the solubilizing and bridging effects of diethylene glycol dibutyl ether are utilized, the compatibility problem of a high-polarity component and a non-polar silicone oil matrix is solved, and the obtained catalyst has high activity, high regioselectivity and excellent long-term storage stability.

The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, adducts, polymorphs, isomers and derivatives thereof useful as orexin antagonists, their preparation, their use in pharmaceutical compositions, and methods of using orexin antagonists to treat or prevent diseases or conditions mediated by orexin receptor activity.

The invention discloses a method for light-controlled release of TAD in an indole-TAD adduct, and belongs to the technical field of light-responsive reversible chemical reactions. The invention provides a technical scheme of a method for releasing TAD in an indole-TAD adduct in a light-operated manner, a C-N bond in the indole-TAD adduct is activated by light to realize that the TAD-indole adduct releases TAD at a low temperature, and groups in the indole-TAD adduct are regulated and controlled to controllably release TAD under different illumination (wavelength) conditions. The method is simple to operate and mild in condition.

The application relates to the technical field of free radical detection, in particular to a high-sensitivity in-situ capture and detection method of organic free radicals based on a DIPPMPO probe and application, and the method comprises the following steps: adding a chemical probe DIPPMPO into a reaction system containing potential organic free radical precursors, so that the DIPPMPO and organic free radicals generated in a reaction process occur adduct reaction to form a DIPPMPO-free radical adduct which can be detected under liquid chromatography-mass spectrometry conditions; performing high performance liquid chromatography-quadrupole-time of flight mass spectrometry analysis on a mixed solution after the adduct reaction is completed, so that first mass spectrometry data and secondary mass spectrometry fragment information of the DIPPMPO-free radical adduct are obtained; and automatically processing the secondary mass spectrometry data, screening out parent ions with continuous neutral loss as potential DIPPMPO-free radical adduct candidate signals. The application does not need derivatization, is simple to operate, is broad-spectrum and high-efficiency, and can be applied to environmental water samples, biological fluids, chemical reaction liquids or drug metabolism systems.

The present invention relates to the production of butyl acrylate by direct esterification of acrylic acid with butanol, this reaction being catalyzed by sulfuric acid. More specifically, it relates to an improved process for producing butyl acrylate, enabling high-purity butyl acrylate to be obtained, by upgrading both the Michael adducts formed during this process, by thermal and catalytic cracking, in the form of reactants and ester which can be recycled in the process, and the final residue, by hydrothermal gasification in the form of methane and mineral salts.

The invention relates to a fireproofing composition comprising a component A and a component B. The component A comprises a liquid epoxy resin and ammonium polyphosphate. The component B comprises (i) at least one adduct B1 of at least one polyamine having at least three amine hydrogens reactive towards epoxy groups and (ii) at least one epoxide, an ether group containing aliphatic primary diamine B2 and an aliphatic or cycloaliphatic primary diamine B3. The fireproofing composition has a good adhesion to metals, shows a good fireproofing value with low mass loss after passing through the drying oven of the automotive industry and is suitable for spraying.

The invention discloses a method for detecting polysorbate 80 based on an MALDI-MS and UHPLC-Q-TOF / MS. The method comprises the following steps: taking a polysorbate 80 sample, preparing a polysorbate 80 solution by using acetonitrile, respectively carrying out MALDI-MS detection and UHPLC-Q-TOF / MS detection on the polysorbate 80 solution, and determining the content of the polysorbate 80 in the polysorbate 80 sample according to the MALDI-MS and UHPLC-Q-TOF / MS detection results. The method comprises the following steps: acquiring PS80 principal component distribution according to an MALDI-MS (Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry) map: a polyoxyethylene chain delta m / z 44.0 + / -0.2 and an esterified derivative sodium adduct ion gradient peak cluster, and carrying out qualitative analysis on components of the polysorbate 80 in combination with a characteristic interval of m / z 44.0 + / -0.2 in the MALDI map; according to the retention time in the UHPLC-Q-TOF / MS detection result, identifying the monoester, diester and trace unesterified sorbitan in the polysorbate 80. According to the invention, molecular weight distribution analysis and component separation and identification of PS80 are realized.

The invention relates to the technical field of structural adhesives, in particular to an epoxy composition capable of being used for bonding a camera module support and a preparation method of the epoxy composition, and the epoxy composition comprises the following components in parts by weight: 7-10 parts of epoxy resin; 20-25 parts of flexible epoxy resin; 5-10 parts of a core-shell epoxy resin toughening agent; 20-25 parts of a compound filler; 30 to 31 parts of organic hydrazide; and 8-9 parts of a modified amine adduct. The flexible epoxy resin has at least one structural characteristic of a long-chain polyether structure and an indene structure. The compound filler comprises calcium carbonate and silicon dioxide. The epoxy composition capable of being used for bonding the camera module support has the advantages of low precipitation, low curing shrinkage, high bonding strength, low modulus and excellent falling resistance, the reliability of the camera module support structure can be remarkably improved, and the epoxy composition is suitable for application environments of various miniature high-performance camera modules.

The invention discloses a model compound-based lipid oxidation free radical specificity induction and detection method, which comprises the following steps: catalyzing a model compound (cumene / cumene hydroperoxide) or a lipid sample by using iron ions (Fe < 2 + > / Fe < 3 + >) with different valence states, and specifically inducing to generate cumene alkyl free radicals, cumene peroxide free radicals and cumene alkoxy free radicals; the method comprises the following steps: reacting a free radical trapping agent PBN with active free radicals to generate a stable PBN-free radical adduct; the adduct is separated and qualitatively identified by utilizing HPLC-TOF / MS (High Performance Liquid Chromatography-Time of Flight / Mass Spectrometry), and is accurately quantified by HPLC-UV (High The method has the advantages that three key free radicals can be specifically distinguished and quantified, the sensitivity is high, the repeatability is good, the method is suitable for free radical analysis from a model system to a complex grease sample, and a reliable analysis means is provided for research on a lipid oxidation mechanism.

An example of a nitric oxide (NO) generating system includes an NO generating formulation, having: a stable NO donor / adduct; a hydrophilic binder; and an additive. The additive is to control a rate of release of NO from the stable NO donor / adduct after the formulation is exposed to an effective amount of water, water vapor, or blue or ultraviolet (UV) light. This example NO generating system further includes an inhalation device in operative contact with the NO generating formulation.

An object of the present invention is to provide a solid-phase carrier for nucleic acid synthesis, in which a nucleic acid and an adduct can be easily separated by HPLC in a case where the nucleic acid is synthesized using the solid-phase carrier for nucleic acid synthesis and the nucleic acid is cut out, a compound which serves as a linker of the solid-phase carrier, a compound which serves as a precursor of the linker, and a method for producing a nucleic acid using the solid-phase carrier. The compound according to the embodiment of the present invention is a compound represented by the following general formula (1).In the general formula (1), Ar represents a tri- to tetracyclic aromatic ring which may have a substituent, Z represents a hydrogen atom or a protective group eliminable by an acid, and R1 to R4 each independently represent a hydrogen atom, an alkyl group, or an alkoxy group.

A method of forming high quality a-BN layers. The method includes use of a precursor chemistry that is particularly suited for use in a cyclical deposition process such as in chemical vapor deposition (CVD), atomic layer deposition (ALD), and the like. In brief, new methods are described of forming boron nitride (BN) layers from precursors capable of growing amorphous BN (a-BN) films by CVD, ALD, or the like. In some cases, the precursor is or includes a borane adduct of hydrazine or a hydrazine derivative.

The application provides a method for preparing low-chlorinated impurity isocyanate, and belongs to the technical field of isocyanate. The method is characterized in that two pretreatments are performed before isocyanate refining. On the one hand, naphthenes are used to extract the phosgenation reaction liquid, and insoluble substances such as urea and carbodiimide are removed before phosgene removal, thereby effectively reducing the generation of phosgene adducts. On the other hand, phosgene synthesis tail gas, phosgenation reaction tail gas and isocyanate refining tail gas are collected and mixed as stripping agents according to the target gas composition, and stripping treatment is performed in the phosgene removal stage. By controlling the source and gas composition of the stripping agent, phosgene can be quickly removed, the high-temperature polymerization of isocyanate and the generation of phosgene adducts can be inhibited, the generation of chlorinated isocyanate impurities can be reduced from the root, and the product quality is significantly improved.

To provide a shrinkage reducing agent for a geopolymer, which has a high effect of reducing both self-shrinkage and drying shrinkage of the geopolymer and does not need to be used in combination with other components.SOLUTION: A shrinkage reducing agent for a geopolymer, comprising an ether compound which is an alkylene oxide adduct of a monohydric to decahydric alcohol having 3 to 15 carbon atoms, wherein an average number of moles of an alkylene oxide having 2 to 4 carbon atoms added is 1 to 50 moles per mole of the alcohol, and 50 mol% or more of the entire alkylene oxide is propylene oxide.SELECTED DRAWING: None

The invention belongs to the technical field of isotope recovery and separation, and discloses a method for recovering high-abundance C13 carbon dioxide from C13 urea based on acidic constant-temperature hydrolysis. According to the method, the hydrolysis rate of the C13 urea is maintained by selecting proper dilute sulfuric acid concentration, sulfate radicals and urea are prevented from forming an adduct by controlling the dilute sulfuric acid concentration, the release efficiency of the 13CO2 is increased, the reaction rate is controlled, and side reaction is avoided. The invention further provides a set of reaction device for recycling 13CO2 through acidic constant-temperature hydrolysis of C13 urea under reduced pressure, the gas-liquid phase contact area and residence time are remarkably increased by arranging the rectifying column, visual water removal and low temperature are realized through the water removal column and the condenser pipe, the problems of external CO2 pollution, high impurity air content and relatively high water content are solved, and the method is suitable for industrial production. And high abundance recovery of the 13CO2 is ensured.

The present invention relates to compounds of Formula I, or pharmaceutically acceptable salts, solvates, adducts, polymorphs, isomers such as stereoisomers and diastereomers, or derivatives thereof, that are useful as orexin antagonists, their preparation, their use in pharmaceutical compositions, and methods of using orexin antagonists to treat or prevent a disease or disorder mediated by orexin receptor activity.

The present invention relates to compounds of formula (I) that are useful as orexin antagonists, or pharmaceutically acceptable salts, solvates, adducts, polymorphs, isomers and derivatives thereof, their preparation, their use in pharmaceutical compositions, and methods for treating or preventing diseases or disorders mediated by orexin receptor activity using orexin antagonists. JPEG2026524754000299.jpg39149

Disclosed is a method of depositing thin film, the method comprising: supplying an adduct precursor to the inside of a chamber in which a substrate including at least one gap feature is placed so that the adduct precursor is adsorbed to the substrate; purging the interior of the chamber; and supplying a reaction material to the inside of the chamber so that the reaction material reacts with the adduct precursor to form the thin film and fill the gap feature, wherein the adduct precursor is formed by mixing 1 to 5 moles of a compound and 1 to 5 moles of a metal compound.

The present invention provides a thermal- and UV-curable (meth)acrylate composition comprising:(A) an epoxy resin,(B) a (meth)acrylate,(C) a photoinitiator,(D) a thiol curing agent, and(E) a catalyst mixture containing (e-1) an epoxy-adduct polyamine, (e-2) a microcapsule type hardener for an epoxy resin comprising a core and a shell, and (e-3) a urea-modified imidazole, wherein the weight ratio of the component (e-2) to the component (e-3) is not lower than 2.1. The present invention also provides a method for preparing the composition, a method for curing the composition, a cured product obtained from the composition or by the curing method, an article comprising the cured product, and a use of the composition or the cured product in assembling a camera module.

The invention relates to the technical field of food chemistry, and particularly discloses an oxidized triglyceride mass spectrum analysis method based on a thermal oxidation reaction mechanism and a mass spectrum fragmentation rule prediction spectrum library, which comprises the following steps: P1, constructing possible oxidized acyl chains based on the types of unsaturated fatty acids in common vegetable oil and oxidation mechanisms of different double bond sites of molecules of the unsaturated fatty acids, predicting the molecular structure of the oxidized triglyceride according to the acyl chain composition and the Cartesian product, and calculating the molecular formula, molecular mass and adduct ion mass of the oxidized triglyceride; p2, calculating mass spectrum collision induced dissociation core fragments according to general laws of different types of oxidized triglyceride, and constructing primary and secondary prediction spectrum libraries of oxidized triglyceride; p3, collecting sample data based on a non-targeted liquid chromatography-mass spectrometry method; p4, annotating and identifying oxidized triglyceride molecules in the vegetable oil sample; according to the method, high-throughput detection of oxidized triglyceride molecules in vegetable oil can be realized without complicated pretreatment and enrichment methods.

The reliability of a light-emitting device is improved. Provided is a light-emitting device including a light-emitting layer between a first electrode and a second electrode. The light-emitting layer contains a light-emitting substance and a first organic compound. A difference between a sum of energy of the first organic compound in a ground state and energy of an oxygen molecule in a ground state and energy of a transition state formed by the first organic compound and the oxygen molecule is greater than or equal to 1.84 eV. A difference between the energy of the transition state formed by the first organic compound and the oxygen molecule and energy of an oxygen adduct of the first organic compound in a ground state is less than or equal to 0.87 eV.

Described herein are gilsonite-based adducts and polymers and methods of making the same. Gilsonite may be modified with a reagent such as polyphosphoric acid. The reagent may modify the gilsonite or portions or moieties thereof to possess a positive charge. The reagent may also activate the gilsonite or portions thereof to enable epoxy and / or urethane polymerization reactions within the gilsonite or portions thereof, and / or to enable cross-linking of the gilsonite-based polymers or adducts. Products incorporating gilsonite-based polymers and adducts are also described.

The present invention relates to a waterborne amine hardener composition (H) comprising a) an adduct (PAd) of an epoxy resin (E) and phosphorus-derived acids (P), wherein the adduct (PAd) is substantially free of epoxy groups and has an acid value of at least 10 mgKOH / g; b) a polyamine (A); and c) water; the molar ratio between the epoxy groups from the epoxy resin (E) and the acidic hydrogen atoms from the phosphorus-derived acids (P) being between 0.2 and 0.95, and the molar ratio between the acidic hydrogen atoms comprised in the adduct (PAd) and the basic nitrogen atoms from the polyamine (A) being between 0.02 and 0.90. The present invention also relates to the process for the preparation of a waterborne amine hardener composition (H) and to the use thereof for coating a substrate. It also relates to waterborne two-pack and three-pack coating compositions.

A cycloheptenone adduct of flavanols and stilbene compounds as shown in formula (I), its preparation method, and its use in treating cerebral ischemia. The compound of this invention has a simple preparation method and exhibits good neuroprotective activity.

A compound of formula (I) wherein R1 is H or methyl, R2 and R3 are independently selected from H, C1-C4 alkyl, cycloalkyl and phenyl-C1- C4-alkyl, or R2 and R3, together with the carbon atom to which they are attached, form a C3-C6 carbocycle, R4 is H or C1-C4 alkyl, and A is C2-C7-alkylene is a suitable precursor for polyisocyanate-adducts and crosslinkers for obtaining isocyanate-free urethane-type polymers.

The invention provides for a screening assay-using a selective proteolysis of recombinant full-length PIKfyve at an endogenous caspase 3 cleavage site to liberate the 34 kDa C -terminal kinase domain. Despite instability of the kinase domain to isolation, the liberated kinase domain is stable in the presence of the N-terminal PIKfyve protein fragment and can thus be treated with compounds of interest and analyzed by mass spectrometry, such as RapidFire-MS, with each injection taking under one minute. The assay was established to triage small molecules for covalent modification of PIKfyve. The assay was also established using cysteine-mutant proteins, where the reactive cysteine was replaced with an inert amino acid which when run through the same experimental protocol, was used to confirm adduct formation at the target cysteine.