43 results about "Coronene" patented technology

The invention provides a coronene derivative probe and a preparation method thereof and a protein detection method based on the coronene derivative probe and aptamer. The objective of the invention is to overcome the problems of tedious operation, complex process and low sensitivity of a conventional protein detection method. The probe is 1,2,7,8-tetra-(4-trimethylamine butyloxycarbonyl)-coronene and has four charges and water solubility. The invention provides the preparation method for the coronene derivative probe. The invention further provides the protein detection method based on the coronene derivative probe and the aptamer. The protein detection method is marker-free, simple and fast and does not need covalent modification; moreover, a fluorescence enhanced signal is given out in detection, so compared with a fluorescence weakened signal, higher sensitivity is obtained.

The invention discloses three-dimensional nanometer graphene based on triptycene and a synthetic method thereof. The three-dimensional nanometer graphene based on the triptycene is a novel coronene-modified triptycene derivative. The preparation method comprises the following steps of: firstly carrying out a Sonogashira coupling reaction on triiodo triptycene to obtain a tri-acetenyl triptycene derivative; then carrying out a Diels-Alder reaction on the tri-acetenyl triptycene derivative to obtain a coronene triptycene derivative; finally carrying out an FeCl3 oxidation and cyclization reaction in an organic solvent (dichloromethane) under the conditions of gas protection (Ar) and normal temperature for 15-240 minutes to obtain the three-dimensional nanometer graphene based on the triptycene. The preparation method disclosed by the invention is novel and higher in yield. The prepared three-dimensional nanometer graphene based on the triptycene disclosed by the invention has an outstanding effect on the aspect of cell imaging.

The present invention relates to a 1, 5, 9-trisubstituted coronene compound and a synthesis method thereof. The structural formula of the compound is shown in img file = 'dest _ path _ image 001. TIF 'wi = '109 'he = '108', wherein R represents H, C1-C18 alkyl, phenyl, 4-methylphenyl, 4-methoxy phenyl, benzyl, cyclohexyl, 4-trifluoromethylphenyl, thiophene, furan and the like. According to the technical scheme of the invention, the easily prepared 1, 5, 9-triamido triphenylene is subjected to diazotization and halogenation reaction to obtain the tri-halogenated triphenylene. After that, the tri-halogenated triphenylene is subjected to Sonogashira reaction with various alkynes to generate atriyne-triphenylene compounds. Finally, through the metal-catalyzed reaction and the cyclization reaction under the effect of an organic base, various 1, 5, 9-trisubstituted coronene compounds, novel in structure, can be obtained. According to the technical scheme of the invention, raw materials are easy for mass preparation. Meanwhile, the synthesis step is relatively short and the operation is convenient. The obtained trisubstituted coronene compound is good in thermal stability and chemical stability, and the trisubstituted coronene emits the relatively strong fluorescence within the range of 420-550 nm according to the fluorescence emission spectrum of the trisubstituted coronene compound. Therefore, the trisubstituted coronene is an excellent fluorescent material for preparing UV ultraviolet charge-coupled devices (UV-CCD) and organic light-emitting diodes (OLEDs), and has a wide application prospect in the field of electronic materials.

The invention relates to a synthon and a method for preparing dibenzocoronene compounds by the same. The synthon is a tetrahydroxy-substituted perylene bisimide compound, and has a structure as shown in general formula (I), wherein R is a C1-C18 linear chain primary alkyl or a primary alkyl with a branched chain. According to the invention, dibromo-perylene anhydride or mixtures are used for preparing dibromo-imide; dibromo-imide and phenylboronic acid substituted by alkoxys at 3 and 4 positions are subjected to a Suzuki coupling reaction under the catalysis of Pd(PPh3)4 to prepare aryl-substituted perylene bisimide compounds; further dealkylation reaction is carried out under the action of boron tribromide so as to form tetrahydroxy-substituted perylene bisimide compound synthon; then the synthon is used as a raw material to synthesize charge transfer compounds of coronene compounds with imide groups at two sides of the molecule. The synthetic method of the invention is simple, high in yield, and widely applicable to organic light-emitting diodes, field effect transistors, and solar cells. The general formula (I) is shown in the description.

The invention relates to coronene compound containing thioether in lateral chain and the preparation method thereof. The structural formula of the compound is shown in the descriptiopn: R refers to alkyl. In the method, ring trimerization- ferric trichloride coronene method, namely 2- (4'- bromophenyl) ethanol is taken as raw material, through hydroxyl bromo, thioether is formed, palladium-catalyzed is selected for direct coupled reaction, so as to obtain diphenylacetypene ramification, under the catalysis of cobalt carbonyl, corresponding hexaphenylbenzene is produced by trimerization cyclization. Anhydrous ferric trichloride is oxidized in methylene dichloride and nitromethane, then reduction is performed by using iodine and sodium borohydride system, and after drying, THF (tetrahydrofuran) is used for recrystal. The synthetic method provided by the invention is simple, is high in yield, and can be extensively used in organic LBD, field-effect tubes and solar batteries.

The invention discloses a method for preparing graphene aqueous solution by using a water soluble coronene derivative as a solubilizer, which comprises: dispersing graphene solid in ultrapure water, adding the water soluble coronene derivative, mixing, adding hydrazine hydrate, stirring, centrifuging, removing supernate, dissolving precipitate in ultrapure water, and thus, obtaining graphene aqueous solution. In the invention, the operation is simple, the property of the prepared graphene aqueous solution is stable, the dispersion state of the graphene in water can be regulated by changing the used amount of solubilizer, and the method has a bright application prospect in nano science, biomedicine and material science.

The invention discloses an application of 6-tertiary butyl-6-hexyloxy-6-benzo[a,b,de,lm,op,rs,uv]coronene as an MALDI-TOF MS matrix in micromolecule detection. Small molecules comprise amino acid, medicine micromolecules, saccharide micromolecules, aromatic hydrocarbon compounds and the like. 6-tertiary butyl-6-hexyloxy-6-benzo[a,b,de,lm,op,rs,uv]coronene based on nano graphene has the characteristic of graphene, can be dissolved into an organic solvent, is not prone to fly away from a target plate as the MALDI-TOF MS matrix, and rarely has pollution to an ion source, the defect that a traditional matrix is poor in micromolecule measuring effect is overcome, and 6-tertiary butyl-6-hexyloxy-6-benzo[a,b,de,lm,op,rs,uv]coronene has the good effect when used for detecting MALDI-TOFMS of multiple kinds of micromolecules.

The invention relates to a 1, 5, 9-triazanaphthalene coronene compound and a synthetic method thereof. The compound has a structural formula as shown in the description, wherein R represents any one of hydrogen, alkyl, aryl, heterocyclic aryl, trifluoromethyl and perfluoroalkyl. The synthetic method disclosed by the invention comprises the following steps of: utilizing cheap 2, 3- dichloronitrobenzene which is easy to obtain as a raw material to prepare trinitro type substances; reducing the trinitro type substances so as to obtain triamine type substances; enabling the triamine type substances to react with acyl chloride or anhydride so as to obtain triamide type compounds; and cyclizing the triamide compounds so as to obtain substituted 1, 5, 9-triazanaphthalene coronene compounds in novel structures. The synthetic method is few in synthetic steps, mild in reaction conditions, convenient to operate and high in yield. The fluorescence emission spectrum of the triazanaphthalene coronene compound in an organic solvent has stronger fluorescence within the range of 420-550nm; the triazanaphthalene coronene compound has favorable heat stability and chemical stability, and can be used for preparing luminescent materials of organic light-emitting diodes and organic semiconductor materials.

Provides is a nano supramolecular assembly body of a fully methylated beta-cyclodextrin modified coronene derivative. A chemical formula of a construction unit of the assembly body is C184H248N6O70, a chemical structural formula of the assembly body is shown in the description, the supramolecular assembly body is established through intermolecular pi-pi interaction, the assembly body is a nanoscale and clubbed aggregate in morphological size. The nano supramolecular assembly body has the advantages that the preparation method of the nano supramolecular assembly body of the fully methylated beta-cyclodextrin modified coronene derivative is simple and convenient, the yield is high, the assembly body has good fluorescent properties; the supramolecular assembly body has good selectivity to nitro aroma compounds, has low detection limit to a polynitro explosive compound 2,4,6-trinitrophenol and has the wide application prospect in the field of fluorescence sensing detection.

The invention relates to a boron-nitrogen doped pine compound and a preparation method thereof. The structural formula of the compound is: in the formula, R is phenyl, methylphenyl, tert-butylphenyl, trifluoromethylphenyl, bis(trifluoromethyl)phenyl, mesityl, naphthyl, etc.; R' is H, C4-C18 alkyl, phenyl, methylphenyl, methoxyphenyl, fluorophenyl, trifluoromethylphenyl, tert-butylphenyl, naphthyl, benzyl, ring Hexyl, pyridyl, thienyl or 2,4,6-trimethylphenyl, etc. The boron-nitrogen-doped pine compound of the present invention has good thermal stability, and the fluorescence emission spectrum in an organic solvent has strong fluorescence in the range of 380-500 nm, and its band gap can be opened after boron-nitrogen doping , and has great application prospects in the fields of hydrogen storage, biomedicine, coordination chemistry, catalysis, and electronic devices.

The invention discloses a preparation method of coronene. The preparation method comprises the following steps: coupling reaction: subjecting 1 equivalent of compound shown in a formula I and 4.2-5.6 equivalent of compound shown in a formula II to coupling reaction and converting a reaction product to a compound shown in a formula III; ring closing reaction: subjecting the compound shown in the formula III to ring closing reaction in the presence of acid and converting a reaction product to coronene shown in a formula IV, wherein the formulas I, II, III and IV are shown in the specification. The preparation method has the beneficial effects that the preparation method is simple in process and is easy to operate; the required raw materials are available and are low in costs; therefore the preparation method is suitable for large-scale production.

The invention provides a flame-retardant ethylene propylene diene monomer, and relates to the technical field of high molecular materials. The flame-retardant ethylene propylene diene monomer is prepared from the following composition raw materials: 80 to 100 parts of ethylene propylene diene monomers, 20 to 25 parts of aluminum silicate fiber cotton, 23 to 28 parts of ore slag fiber cotton, 12 to 18 parts of sepiolite fiber cotton, 3 to 7 parts of vermiculite, 14 to 19 parts of expanded perlite, 8 to 13 parts of fiber cement boards, 3 to 8 parts of fiber enhanced calcium silicate boards, 5 to 12 parts of pentaerythrite oleate, 4 to 8 parts of abietic resin, 5 to 9 parts of boric acid, 11 to 15 parts of coronene, 6 to 10 parts of rhodium, 11 to 13 parts of asphalt coal tar, 9 to 16 parts of plasticizers and 17 to 22 parts of light stabilizers. The flame-retardant ethylene propylene diene monomer has the beneficial effects that the price of the raw materials is cheap; the manufacturing process is simple; the flame retardant effect of the prepared ethylene propylene diene monomer is good; no harm is caused on human bodies in the production process.

The invention discloses a preparation method of a coronene compound. The method comprises the following steps of: (1) pretreating a catalyst containing an SAPO molecular sieve; and (2) filling a reactor with a raw material containing non-cyclic olefin, and carrying out contact reaction with the catalyst pretreated in the step (1) to obtain the coronene compound, wherein the pretreatment refers toactivation of the catalyst. The method does not need expensive raw materials or complex operation, and is suitable for large-scale production.