20 results about "Supramolecular assembly" patented technology

This invention provides an organic ferroelectric eutectic material, its preparation method, and its applications, relating to the field of ferroelectric materials technology. The organic ferroelectric eutectic material constructs a crystal system with "rigid constraint and flexible adaptation coexisting, dipole order and controllable polarization synchronously" through "molecular selection-supramolecular assembly-crystal structure regulation," achieving a synergistic effect of high Curie temperature, strong polarization characteristics, and excellent flexibility. The preparation method of the organic ferroelectric eutectic material utilizes a simplified "solvent dissolution-solvent evaporation" process, leveraging the mediating effect of the solvent to promote the supramolecular self-assembly of donor and acceptor molecules. This achieves the preparation of an organic ferroelectric eutectic material possessing both high Curie temperature, strong polarization characteristics, and excellent flexibility. The preparation method has multiple advantages, including "stable process, low cost, and suitability for large-area processing," making it a simple, efficient, and universally applicable preparation method suitable for large-scale industrial production.

The application discloses a supramolecular lotus leaf peptide-narcotic alkaloid Pickering emulsion as well as a preparation method and application thereof. The water phase of the supramolecular lotus leaf peptide-narcotic alkaloid Pickering emulsion is a purified lotus leaf peptide aqueous solution, and the oil phase is camellia seed oil loaded with narcotic alkaloids. The camellia seed oil not only serves as a fat-soluble carrier to improve the solubility of the narcotic alkaloids, but also has nursing effects due to the unsaturated fatty acids, vitamin E and phytosterols contained therein. The supramolecular assembly technology is used to mediate the lotus leaf peptide and the narcotic alkaloids to form high-performance emulsified particles, to replace synthetic surfactants to stabilize the Pickering emulsion, and to construct a natural emulsion system with high emulsification efficiency, high stability and high performance, so that the performance and the nursing effect of the emulsion are optimized.

This invention discloses a carbon nitride homojunction photocatalyst for the selective conversion of methane to ethanol, its preparation method, and its application, belonging to the field of photocatalysis. The carbon nitride homojunction photocatalyst for the selective conversion of methane to ethanol is made of carbon nitride semiconductor CNC. I Axially oxygen-coordinated copper single-atom co-catalyst and carbon nitride semiconductor CN II Composition. Based on carbon nitride semiconductor CN. I The first semiconductor is formed by supramolecular assembly and thermal polymerization, on which an axially oxygen-coordinated copper single-atom co-catalyst and a second semiconductor CN are simultaneously introduced. II The carbon nitride homojunction photocatalyst for the selective conversion of methane to ethanol, denoted as Cu-CN, was prepared. II / CN I The catalyst used in this invention is made from abundant and inexpensive raw materials, and its preparation route is simple. The prepared catalyst significantly promotes the separation of charge carriers and exhibits excellent catalytic performance in the photocatalytic conversion of methane to ethanol, showing broad application prospects.

The invention discloses an engineered adoptive macrophage based on a nano battery as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The preparation method disclosed by the invention comprises the following steps: taking an immunologic adjuvant working solution as a raw material, and obtaining nanoparticles with high drug loading capacity through an assembly effect; as the main energy of ChARM comes from an immunologic adjuvant, the high-drug-loading nano-particle is also called a high-energy-density nano-battery. Diluting the obtained nano particles with a cell culture medium, and co-incubating the diluted nano particles and macrophages to obtain engineered macrophages loaded with the anti-tumor or anti-inflammatory nano battery; the assembly mode is any one of supramolecular assembly, prodrug assembly or metal coordination assembly; the high-density drug-loaded nano battery can endow engineered cells with excellent biological functions. The method solves the technical problems that the preparation of the existing CAR-M is expensive, the gene modification is complex, and the nano-drug delivery system is unstable.

This invention discloses a method and apparatus for preparing dihydroporphyrin supramolecular assemblies, belonging to the field of functional nanomaterials technology. By designing a Y+S composite microfluidic chip, this invention utilizes Dean's vortex induced by an S-shaped flow channel to precisely control the nucleation and growth kinetics of Ce6 molecules, achieving the directional preparation of nanospherical Ce6 supramolecular assemblies. Simultaneously, it ensures that the assemblies have a narrow particle size distribution (PDI < 0.1), completely solving the problems of large morphological heterogeneity and poor controllability in traditional methods, and providing technical support for the standardized preparation of Ce6-based nanodelivery systems.

The application discloses a phenylpyridine salt derivative G, a room-temperature phosphorescent supramolecular gel and a preparation method and application thereof. The preparation method of the room-temperature phosphorescent supramolecular gel comprises the following steps: taking Cucurbit[8]uril (CB[8]) as a host, a phenylpyridine salt derivative containing a urea-based pyrimidone (UPy) quadruple hydrogen bond site as a guest, self-assembling a supramolecular assembly phosphorescent material in a 1:2 molar ratio in an aqueous solution; and introducing the assembly into a polyvinyl alcohol (PVA) matrix to obtain a humidity-responsive room-temperature phosphorescent supramolecular gel. The assembly and the supramolecular gel both present phosphorescent emission at room temperature. Under the dual constraints of macrocycle limitation and multiple hydrogen bonds on the phosphorescent molecules, the phosphorescent intensity and lifetime of the supramolecular gel are greatly enhanced compared with the assembly. Meanwhile, the phosphorescent intensity and the light-emitting color of the supramolecular gel change with the water content of the gel or the environmental humidity, realizing a visual response from green to blue, and the supramolecular gel can be applied to humidity sensing, anti-counterfeiting and information encryption.

This invention relates to the field of building materials and concrete admixtures, and particularly to a hydration temperature rise inhibitor, its preparation method, and its application. The hydration temperature rise inhibitor of this invention employs a host-guest supramolecular assembly strategy, using calixarene as the host and polyhydroxy compounds as the guest, constructing a capsule-like composite structure through hydrogen bonding. During cement hydration, calixarene is first adsorbed onto the surface of cement particles, delaying the nucleation and growth stages of cement hydration through interfacial adsorption. Subsequently, the calixarene gradually dissolves and continuously releases polyhydroxy compounds, allowing them to enter the aqueous phase. The released polyhydroxy compounds further effectively inhibit the interfacial reaction process of cement hydration, thereby slowing down the hydration heat release rate, reducing the hydration temperature peak, and achieving regulation of the early hydration temperature rise of cement. The hydration temperature rise inhibitor has wide applicability, significantly reducing the risk of concrete cracking caused by temperature drop shrinkage, and effectively improving the durability and long-term safety of engineering structures.

Disclosed is a supramolecular polyhedron comprising 12 identical macrocyclic molecules wherein the macrocyclic molecules interact via 144 C-H hydrogen bonds, including 24 [C-H... F], 48 [C-H... O], and 72 [C-H... Pi]. A supramolecular assembly, a composite system, a crystalline material, and a porous material are also disclosed. The invention further discloses application of the supramolecular polyhedron, the supramolecular assembly and the composite system. Further, the invention discloses a preparation method.

The application belongs to the technical field of biological medicine, and discloses a kind of construction and application of biologic macromolecule gel microspheres that can be assembled.The application discloses a kind of gel microspheres, including gel microsphere 1 and / or gel microsphere 2.The application provides a kind of gel microspheres, which are delivered to pathological sites by the specific targeting effect of fucoidan on damaged endothelial cells.Further, gel microsphere 1 and gel microsphere 2 overcome the limitation of steric hindrance by supramolecular assembly between adamantane and cyclodextrin, provide more drug targeting anchor points, thereby improving the drug concentration at the pathological site to enhance the therapeutic efficacy of IBD.The assembly strategy of the gel microspheres provides an effective method for enhancing the drug concentration of micron-sized oral drugs at the pathological site, and provides a new idea for the delivery of micron-sized oral drugs.

A method for preparing photophosphorylated nanorobots for targeted therapy of myocardial injury is disclosed. This invention aims to construct self-driven nanorobots with near-infrared light response capabilities to achieve targeted in-situ ATP supply and repair of damaged myocardium. The nanorobots of this invention are constructed based on supramolecular assembly and phospholipid phase separation principles, incorporating F-containing... o F l The pigment clusters of the ATPase and photophosphorylated protein system were co-extruded with synthetic phospholipids to form a hybrid structure with near-infrared light responsiveness. Under 850 nm near-infrared light activation, F… o F l -ATPase synergistically rotates and synchronously generates ATP, while simultaneously enhancing the directional movement capability of the nanorobots. These nanorobots can actively accumulate in areas of myocardial injury in vivo, achieving efficient lysosomal escape and deep tissue penetration, and providing in-situ ATP supply within cells to increase energy levels, restore mitochondrial function, and complete myocardial repair. This invention belongs to the field of nanorobots.

This invention discloses an oligomeric surfactant, a biodegradable broad-spectrum and highly efficient bactericide, and their preparation and application. The preparation method includes: mixing 18-nitro-2,3,5,6,8,9,11,12,14,15-decahydrobenzo[b][1,4,7,10,13,16]hexaoxane with a first catalyst and reacting under a hydrogen atmosphere to obtain an intermediate product; mixing the intermediate product with a second catalyst to obtain a crown ether head compound; and reacting the crown ether head compound with dodecylamine and / or heptadecanenonamine to obtain an oligomeric surfactant based on supramolecular assembly. This invention constructs two oligomeric surfactants C 12 N@BDHD and C 17‑9 N@BDHD was used to achieve highly efficient sterilization of bacteria such as Escherichia coli and Staphylococcus aureus by utilizing two oligomeric surfactants.

The application relates to the technical field of supramolecules, in particular to a pillar[n]arene derivative-DCOIT slow-release supramolecular self-assembly body, application and a preparation method. The supramolecular self-assembly body loads DCOIT by taking a pillar[n]arene derivative as a molecular carrier; the pillar[n]arene serving as the carrier can form a supramolecular assembly body with DCOIT through hydrogen bond interaction between pi and CH2, the host-guest complexation of the two is strong, and the pillar[n]arene derivative can effectively control the slow release of DCOIT; the supramolecular self-assembly body is good in safety and stability, low in cost, beneficial to industrialized production, and wide in application field; the method is simple in operation, low in preparation cost, easy to realize, and beneficial to industrial promotion.

The present disclosure belongs to the technical field of piezoelectric materials and industrial catalysis, and provides a piezoelectric functional material, a preparation method of the piezoelectric functional material and a water pollution treatment method. The piezoelectric functional material is prepared by supermolecular assembly and melamine complex transition metal monatomic, has the advantages of simple process, mild conditions and convenient operation, and has the characteristics of increased specific surface area, increased reaction active sites, low charge transport impedance and enhanced piezoelectric performance. The piezoelectric functional material can also construct a synergistic system with persulfate in water pollution treatment, realize rapid degradation of organic pollutants such as carbamazepine, and effectively improve the water pollution treatment efficiency.

This invention relates to the field of microelectronic device technology, and more particularly to a single-molecule memristor-rectifier device based on supramolecular assembly and its fabrication method. The fabrication method involves covalently linking a guest molecule B to the ends of a graphene electrode pair, ensuring a stable and tight interfacial bond between the supramolecular functional molecule and the electrode. Subsequently, the graphene electrode pair connected to the guest molecule B is immersed in a solution containing a host molecule A and a guest molecule C, forming a supramolecular functional molecule between the graphene electrode pairs. The guest molecule C in the supramolecular functional molecule possesses intrinsic redox activity; its molecular structure itself can undergo reversible electron gain and loss processes, thereby achieving controllable and reversible adjustment of the intramolecular charge distribution. Under the influence of an electric field, the reversible redox reaction of the guest molecule C triggers significant changes in the intramolecular charge distribution and electron transport characteristics, ultimately achieving reliable switching between high and low resistance states of the device.

To address the growing challenge of antibiotic resistance globally, this invention develops a Fmoc-tyrosine / berberine chiral supramolecular antibacterial hydrogel with photodynamic therapy. This is achieved by exploring the synergistic effect of berberine (BBR) in supramolecular chiral assembly. Berberine, the main active ingredient in the traditional Chinese medicine (TCM) Coptis chinensis, co-assembles with Fmoc-tyrosine (Fmoc-Y) to form a chiral supramolecular antibacterial hydrogel, effectively utilizing the chirality of amino acids and the antibacterial potential of BBR. Studies have confirmed that supramolecular assembly possesses photodynamic therapy (PDT) capabilities. Under white light, the chiral supramolecular assemblies can effectively generate type I and type II free radicals, enhancing their antibacterial activity against common bacteria such as Escherichia coli and Staphylococcus aureus. Furthermore, the chiral hydrogel exhibits good biocompatibility, low cytotoxicity, and hemolytic activity, indicating its potential application in the field of safe biomedicine. This invention demonstrates the therapeutic potential of combining TCM compounds with supramolecular chiral assembly, opening up a new treatment approach for bacterial infections and addressing antibiotic resistance.

This invention belongs to the field of chemical energy storage battery technology, specifically providing a chiral hydrogel electrolyte based on supramolecular assembly and its preparation method, to solve the problems of disordered ion channels and insufficient free water binding in traditional achiral gel electrolytes. This invention introduces a single, pure-configuration chiral guest molecule into an achiral polymer substrate, forming a supramolecular chiral membrane based on stereo-oriented supramolecular assembly. After swelling and saturation in an aqueous electrolyte, a chiral hydrogel electrolyte is obtained. The chiral guest molecule, acting as a topological guest, reshapes the polymer topology network, forming a stereo-oriented network, causing a sudden leap in the gel's energy storage modulus, thus providing resistance to dendrite penetration. Simultaneously, the chiral guest molecule can achieve interfacial stability at the negative electrode, further suppressing dendrite formation at the negative electrode. Furthermore, the stereo-oriented network can significantly limit the activity of free water molecules, eliminating the erosion of the vanadium cathode by free water molecules and vanadium dissolution.

The application discloses a supramolecular assembly tannic acid-zinc nanoparticle and application thereof in cosmetics. The supramolecular assembly tannic acid-zinc nanoparticle is an aggregate structure formed by tannic acid and zinc pyrrolidone carboxylate through non-covalent interaction. A preparation method of the supramolecular assembly tannic acid-zinc nanoparticle comprises the following steps: ultrasonic treatment is conducted on a mixed solution composed of tannic acid, zinc pyrrolidone carboxylate and a solvent. The supramolecular assembly tannic acid-zinc nanoparticle can effectively exert the synergistic effect of tannic acid and zinc elements, and can guarantee excellent effects such as high stability and high transdermal absorption. The supramolecular assembly tannic acid-zinc nanoparticle itself and further application thereof in cosmetics can simultaneously consider excellent anti-photoaging and oil control effects.

This invention discloses a high-internal-phase Pickering emulsion, its preparation method, and its applications. The emulsion consists of an oil phase and an aqueous phase containing a stabilizer, with a mass ratio of oil to aqueous phase of 1:2 to 3:1. This invention constructs a high-internal-phase Pickering emulsion that is stable for 6 months without the need for chemical emulsifiers through supramolecular assembly of silk fibroin and tea polyphenols, exhibiting excellent antioxidant properties. This all-natural emulsion has good biocompatibility and can significantly enhance the expression of skin barrier proteins FLG and ZO-1, possessing excellent stability, safety, and active repair efficacy.

The application discloses a preparation process of high-activity supramolecular assembly microspheric PDRN and belongs to the field of cosmetic raw material preparation, and contains two stages of PDRN biosynthesis-enzymatic decoupling extraction refinement and supramolecular assembly microspherization. First, PDRN precursors are synthesized through fermentation of genetically engineered Escherichia coli, combined with salmon testis enzyme-assisted extraction, and purified through macroporous resin-ultrafiltration membrane combination to obtain high-purity PDRN pure product; then, through intermolecular hydrogen bonds and hydrophobic interaction, self-assembly is realized by using amphiphilic cyclodextrin derivatives and PEG-PLA as carriers to realize PDRN microspherization, and a crosslinking agent is not needed in the whole process. The prepared microspheric PDRN has a purity of 95%, a particle size of 100-300 nm, an encapsulation rate of 85%, an activity retention rate of 90%, excellent sustained release and stability, no skin irritation, and is suitable for various cosmetic formulations, and the process equipment is conventional, easy to be industrialized, the raw material utilization rate is high, and the process is green and environmentally-friendly.

This invention belongs to the field of functional polymer synthesis and supramolecular assembly, and discloses a polymer with azobenzene side chains. β α-Hydroxy fatty acid esters, their preparation methods, and applications. This poly(hydroxyl fatty acid ester) with azobenzene side chain... β β-hydroxy fatty acid esters are obtained through ring-opening polymerization of four-membered ring lactones containing chiral centers. Practice has shown that this type of polymer, with azobenzene side chains... β The chirality of the hydroxy fatty acid ester backbone is transferred to the azophenyl groups of the side chain, forming a supramolecular assembly with supramolecular chirality and liquid crystal properties that can be regulated by ultraviolet light.