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940 results about "Surface binding" patented technology

A surface (or secondary) binding site (SBS) is a ligand binding site observed on the catalytic module of an enzyme, but outside of the active site itself (see Figure 1). For recent reviews on this topic, please see [2, 3, 4].

Carbon electrode material for a vanadium-based redox-flow battery

The carbon electrode material of the present invention is used for a vanadium redox-flow cell. The carbon electrode material has quasi-graphite crystal structure in which <002> spacing obtained by X-ray wide angle analysis is 3.43 to 3.60 Å, size of a crystallite in c axial direction is 15 to 33 Å and size of crystallite in a axial direction is 30 to 70 Å. In addition, an amount of surface acidic functional groups obtained by XPS surface analysis is 0.1 to 1.2% and total number of surface bound-nitrogen atoms is 5% or smaller relative to total number of surface carbon atoms. The carbon electrode materials formed of a non-woven fabric of a carbonaceouss fiber is preferable.
Owner:TOYO TOYOBO CO LTD

Thermal interface material having a zone-coated release linear

A release liner particularly adapted for use with a layer of a thermal interface material having a first surface and a second surface which is bondable to the heat transfer surface of a thermal dissipation member. The liner has an exterior surface and an interior surface disposable in adhering contact with the first surface of the thermally-conductive material. The liner interior surface has one or more first zones defined thereon which exhibit a first release value relative to the first surface of the thermally-conductive material, and one or more second zones bordered by the first zones which exhibit a second release value relative to the first surface of the thermally-conductive material which is lower than the first release value of the first zones. With the second surface of the thermally-conductive material being bonded to the heat transfer surface of the thermal dissipation member, the release liner is removable from the first surface of the thermally-conductive material without substantial cohesive or adhesive failure thereof.
Owner:PARKER HANNIFIN CORP

Removable adhesive tape laminate and separable fastener

An adhesive tape construction is removable from one or more objects to which it is adhered and which is reusably separable within its construction so that an object can be separated from another and subsequently reconnected with one another. The adhesive tape construction can be used to bond the other opposed surfaces of objects, including rigid objects such as a picture frame to a wall, where no portion of the adhesive tape construction projects from between the objects, and which subsequently affords easy separation of the objects without damage to either of them. More specifically, the adhesive tape construction includes a stretch release adhesive tape structure combined with a reusable connector surface.
Owner:3M INNOVATIVE PROPERTIES CO

Pepetide-based body surface reagents for personal care

Peptides have been identified that bind with high affinity to body surfaces, such as, hair, skin, nails, teeth, gums, corneal tissue, and oral cavity surfaces. Peptide-based body surface reagents formed by coupling a body surface binding peptide to a benefit agent are described. The peptide-based body surface reagents include peptide-based hair conditioners, hair colorants, skin conditioners, skin colorants, nail colorants, and oral care reagents. The peptide-based hair conditioners and hair colorants are comprised of a hair-binding peptide coupled to a hair conditioning agent or a coloring agent, respectively. The peptide-based skin conditioners and skin colorants are comprised of a skin-binding peptide coupled to a skin conditioning agent or a colorant, respectively. The peptide-based nail colorants are comprised of a nail-binding peptide coupled to a coloring agent. The peptide-based oral care reagents are comprised of an oral cavity surface-binding peptide coupled to an oral care benefit agent. In all these compositions, the peptide may be directly coupled to the active agent or the coupling may be via a spacer. Personal care compositions containing these peptide-based body surface reagents are also described.
Owner:EI DU PONT DE NEMOURS & CO

Functional associative coatings for nanoparticles

InactiveUS20080089836A1Readily and efficiently optimizing propertyAvoid interactionBiocidePowder deliveryAmphiphileNanoparticle
Described herein are nanoparticles that are coated with a bilayer of molecules formed from surface binding molecules and amphiphatic molecules. The bilayer coating self assembles on the nanoparticles from readily available materials / molecules. The modular design of the bilayer coated nanoparticles provides a means for readily and efficiently optimizing the properties of the bilayer coated nanoparticle compositions. Also described herein are uses of such nanoparticles in medicine, laboratory techniques, industrial and commerical applications.
Owner:NANOPROBES

Compositions and Methods for Altering Tissue Specificity and Improving AAV9-Mediated Gene Transfer

A method of altering the targeting and / or cellular uptake efficiency of an adeno-associated virus (AAV) viral vector having a capsid containing an AAV9 cell surface binding domain is described. The method involves modifying a clade F cell surface receptor which comprises a glycan having a terminal sialic acid residue and a penultimate β-galactose residue. The modification may involve retargeting the vector by temporarily functionally ablate AAV9 binding in a subset of cells, thereby redirecting the vector to another subset of cells. Alternatively, the modification may involve increasing cellular update efficiency by treating the cells with a neuraminidase to expose cell surface β-galactose. Also provided are compositions containing the AAV9 vector and a neuraminidase. Also provided is a method for purifying AAV9 using β-galactose linked to solid support. Also provided are mutant vectors which have been modified to alter their targeting specificity, including mutant AAV9 in which the galactose binding domain is mutated and AAV in which an AAV9 galactose binding domain is engineered.
Owner:THE TRUSTEES OF THE UNIV OF PENNSYLVANIA

Hybrid silicon laser-quantum well intermixing wafer bonded integration platform for advanced photonic circuits with electroabsorption modulators

Photonic integrated circuits on silicon are disclosed. By bonding a wafer of compound semiconductor material as an active region to silicon and removing the substrate, the lasers, amplifiers, modulators, and other devices can be processed using standard photolithographic techniques on the silicon substrate. A silicon laser intermixed integrated device in accordance with one or more embodiments of the present invention comprises a silicon-on-insulator substrate, comprising at least one waveguide in a top surface, and a compound semiconductor substrate comprising a gain layer, the compound semiconductor substrate being subjected to a quantum well intermixing process, wherein the upper surface of the compound semiconductor substrate is bonded to the top surface of the silicon-on-insulator substrate.
Owner:RGT UNIV OF CALIFORNIA

Continuous process for producing spacer-modified nano Graphene electrodes for supercapacitors

A specific embodiment of the present invention is a process for continuously producing a porous solid film of spacer-modified nano graphene platelets for supercapacitor electrode applications. This process comprises: (a) dissolving a precursor material in a solvent to form a precursor solution and dispersing multiple nano graphene platelets into the solution to form a suspension; (b) continuously delivering and forming the suspension into a layer of solid film composed of precursor material-coated graphene platelets overlapping one another, and removing the solvent from the solid film (e.g., analogous to a paper-making, mat-making, or web-making procedure); (c) continuously converting the precursor material into nodules bonded to surfaces of graphene platelets to form a porous solid film composed of spacer-modified graphene platelets; and (d) continuously collecting the porous solid film on a collector (e.g., a winding roller). The roll of porous solid film (mat, paper, or web) can then be cut into pieces for used as supercapacitor electrodes.
Owner:NANOTEK INSTR GRP LLC

Mitigation of Biomolecular Adsorption with Hydrophilic Polymer Additives

Molecular adsorption to the microfluidic device surfaces can be passively and actively mitigated by mixing certain hydrophilic polymers (organic polymers with repeating hydrophilic groups—the preferred polymers being amphipathic surfactants—with the sample liquid during or prior to relevant microfluidic operations. Nonionic surfactants such as polyoxyethylene sorbitan monooleate and polyoxyethylene octyl phenyl ether are especially effective. High molecular weight polyethylene polymers are also effective. The hydrophilic polymers appear to prevent binding of the fouling molecules to the microfluidic by occupying the surface sites in place of the fouling molecules or by interacting with the fouling molecules to prevent binding of the fouling molecules the surface. When surface adsorption is thus mitigated, microfluidic devices can readily handle samples containing biomolecules to enable active sample concentration, filtering, washing, transport, mixing and other sample handling operations.
Owner:ADVANCED LIQUID LOGIC

Spacer-modified nano graphene electrodes for supercapacitors

A surface-modified nano graphene platelet (NGP), comprising: (a) a nano graphene platelet having a thickness smaller than 10 nm; and (b) discrete, non-continuous, and non-metallic bumps or nodules bonded to a surface of the graphene platelet to serve as a spacer. When multiple surface-modified NGP sheets are stacked together to form an electrode, large numbers of electrolyte-accessible pores are formed, enabling the formation of large amounts of double layer charges in a supercapacitor, which exhibits an exceptionally high specific capacitance.
Owner:NANOTEK INSTR GRP LLC

Oral compositions and use thereof

InactiveUS20040057908A1Cosmetic preparationsToilet preparationsAphthous ulcerationsDental plaque formation
The present invention relates to an oral composition which includes an organoleptically suitable carrier and an amount of a terpenoid and a flavonoid, dispersed in the carrier, which is effective to prevent or treat dental caries, dental plaque formation, gingivitis, candidiasis, dental stomatitis, aphthous ulceration, or fungal infection. The invention also relates to various uses of oral compositions, containing a terpenoid, a flavonoid, or both, such uses include: inhibiting the activity of surface-bound glusosyltransferase; treating or inhibiting dental caries, gingivitis, candidiasis, denture stomatitis; inhibiting the accumulation of microorganisms on an oral surface; and / or treating or inhibiting aphthous ulcerations on an oral surface.
Owner:UNIV ESTADUAL DE CAMPINAS UNICAMP +1

Hard surface-veneer engineered surfacing tiles and methods

A modular tile assembly having a substantially rigid substrate, at least one sealant layer, and at least one stone, ceramic, or porcelain tile. A bottom surface of a first sealant layer being bonded to an upper surface of the substrate and a top surface of a second sealant layer being bonded to a lower surface of the substrate. The tile being bonded to at least a portion of the top surface of the first sealant layer. In one example, the substrate is provided with a tongue or a groove defined in any one, combination, or each of the respective side edges of the substrate, as desired.
Owner:SHAW INDS GROUP

Automated deployable running board

Running board systems are provided. The running board systems employ a motorized drive system that includes a rack-and-pinion system that enables both linear and rotational movement of the running board member, for example, through the use of a pivot member cooperating with one end of the running board member and one end of an arm member. The running board systems are automated and selectively operable to assume deployed and stowed positions. The running board systems can be used in conjunction with various surfaces of a vehicle, such as an aesthetically preferred flush style mounting to the rocker outer sheet metal surface such as but not limited to being mounted underneath a side door sill.
Owner:MAGNA INTERNATIONAL INC

Cultured human pancreatic islets, and uses thereof

A method of generating cells capable of secreting insulin is disclosed. The method comprises subjecting mammalian embryonic stem cells to set of culturing conditions suitable for differentiation of at least a portion thereof into cells displaying at least one characteristic associated with a pancreatic islet cell progenitor phenotype, and subjecting such differentiated cells to a set of culturing conditions suitable for formation of surface bound cell clusters including insulin producing cells.
Owner:TECHNION RES & DEV FOUND LTD

Semiconductor-dielectric-semiconductor device structure fabricated by wafer bonding

A method of forming a gate stack for semiconductor electronic devices utilizing wafer bonding of at least one structure containing a high-k dielectric material is provided. The method of the present invention includes a step of first selecting a first and second structure having a major surface respectively. In accordance with the present invention, at least one, or both, of the first and second structures includes at least a high-k dielectric material. Next, the major surfaces of the first and second structures are bonded together to provide a bonded structure containing at least the high-k dielectric material of a gate stack.
Owner:ELPIS TECH INC

Automated deployable running board

Running board systems are provided. The running board systems employ a motorized drive system that includes a rack-and-pinion system that enables both linear and rotational movement of the running board member, for example, through the use of a pivot member cooperating with one end of the running board member and one end of an arm member. The running board systems are automated and selectively operable to assume deployed and stowed positions. The running board systems can be used in conjunction with various surfaces of a vehicle, such as an aesthetically preferred flush style mounting to the rocker outer sheet metal surface such as but not limited to being mounted underneath a side door sill.
Owner:MAGNA INTERNATIONAL INC

Image photographing device having function for compensating hand vibration

Disclosed herein is an image photographing device having a function for compensating hand vibration. The image photographing device having a function for compensating hand vibration includes: an optical unit; a magnet combined with an outer peripheral surface of the optical unit; a housing inserted with the optical unit and the magnet and having coils disposed at a position corresponding to the magnet; suspension wires arranged at four corners of the optical unit, having the upper end portions and the lower end portions each combined with the optical unit and the housing to support the optical unit in a state floated from the bottom surface of the housing, and having a predetermined bending part formed at any point; a flexible printed circuit board surrounding the outer peripheral surface of the housing and applying current to the coils; and a substrate having the image sensor mounted on the top surface thereof and combined with the lower portion of the housing.
Owner:SAMSUNG ELECTRO MECHANICS CO LTD

Process for producing an isolated planar high speed pin photodiode with improved capacitance

A method is shown for producing a PIN photodiode having low parasitic capacitance and wherein an intrinsic layer of the photodiode can be made arbitrarily thin. A fabrication substrate is lightly doped to have a first conductivity type in order to form the intrinsic layer of the photodiode. A first active region of the photodiode having the first conductivity type is formed on a first surface of the fabrication substrate. An oxide layer is also formed upon the first surface of the fabrication substrate. A first glass layer is formed on a first surface of a handling substrate. The first surface of the handling substrate is bonded to the first surface of the fabrication substrate. A second surface of the fabrication substrate is then lapped to a obtain a preselected thickness of the intrinsic layer. A second active region of the photodiode having a second conductivity type is formed on the second surface of the fabrication substrate. A groove is etched from the second surface of the fabrication substrate through the intrinsic region to the first surface in order to isolate the photodiode. A second glass layer may be formed on a second surface of the handling substrate to further reduce parasitic capacitance.
Owner:SILICON LAB INC

Capacitive Touch Screen Panel

Provided is a capacitive touch-screen panel. The capacitive touch-screen panel includes a first substrate having a screen region and an inactive region, a first transparent electrode pattern unit disposed in the screen region of a first lateral surface of the first substrate, a first outer electrode interconnection formed in the inactive region of the first lateral surface of the first substrate and electrically connected to the first transparent electrode pattern unit, a second substrate having a first lateral surface bonded with a second lateral surface of the first substrate using an interlayer adhesive, the second substrate having a screen region and an inactive region, a second transparent electrode pattern unit disposed on the screen region of a second lateral surface of the second substrate, and a second outer electrode interconnection formed in the inactive region of a second lateral surface of the second substrate and electrically connected to the second transparent electrode pattern unit. The capacitive touch-screen panel is configured to sense a touched position with a variation in capacitance due to a contact with the first and second transparent electrode pattern units. As a result, malfunctions from occurring due to a state of contact with an upper portion of an electrode unit of a touch screen and malfunctions and damage from occurring due to scratches and static electricity during a contact with the touch screen may be prevented. Further, the fabrication cost of a touch screen may be efficiently reduced, and the fabrication process of a touch-screen panel may be greatly simplified.
Owner:E&H

Polymeric coatings and methods for forming them

The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerisation initiators and a plurality of surface binding groups; and pendant polymers grafted from at least some of the polymerisation initiators.
Owner:COMMONWEALTH SCI & IND RES ORG

Method and apparatus for reading reporter labeled beads

Combinatorially-synthesized deoxyribonucleic acid (DNA) oligonucleotides attached to encoded beads that are hybridized to amplified and labeled genomic DNA or ribonucleic acid (RNA) are analyzed using a flow imaging system. Oligonucleotides and corresponding reporters are bound to the surfaces of a plurality of small beads such that different beads bear different oligo sequences. Each bead bears a unique optical signature comprising a predefined number of unique reporters, where each reporter comprises a predefined combination of different fluorochromes. The composite spectral signature in turn identifies the unique nucleotide sequence of its attached oligo chains. This optical signature is rapidly decoded using an imaging system to discriminate the different reporters attached to each bead in a flow in regard to color and spatial position on the bead.
Owner:AMNIS CORP

Friction-nanogenerator-based molecular sensor

The invention provides a friction-nanogenerator-based molecular sensor. The sensor comprises a first conducting element, a first friction layer, a second conducting element, a second friction layer, a modified layer and an elastic connecting component, wherein the first friction layer is placed on the lower surface of the first conducting element in a contact mode, the second friction layer is placed on the upper surface of the second conducting element in the contact mode, and the modified layer is combined with the upper surface of the second friction layer; by the elastic connecting component, the lower surface of the first friction layer is opposite to the upper surface of the second friction layer, and a certain distance is respectively kept between the lower surface of the first friction layer and the upper surface of the second friction layer; the lower surface of the first friction layer is at least partially in contact with the upper surfaces of the second friction layer under the action of external force, and the distance respectively between the lower surface of the first friction layer and the upper surfaces of the second friction layer can be restored under the action of the elastic connecting component when external force is removed, and simultaneously, electrical signals are outputted outwards through the first conducting element and the second conducting element; the electrical signals can be changed after the modified layer is combined with a target material to be detected.
Owner:BEIJING INST OF NANOENERGY & NANOSYST

Fusion NANO liposome-fluorescence labeled nucleic acid for in vivo application, uses thereof and preparation method thereof

The present disclosure relates to a fusion nano liposome-fluorescence labeled nucleic acid in which a bead having a surface binding with a branch-shaped nucleic acid structure labeled with a fluorophore or a branch-shaped nucleic acid structure having a hairpin loop end is included in an inside of a liposome, and a diagnosis application thereof. The fusion nano liposome-fluorescence labeled nucleic acid, or fusion nano liposome-fluorescence labeled hairpin loop structured nucleic acid may sense an external or internal signal, and high-sensitive diagnosis is possible even when mRNA and miRNA which is present at a low concentration in cells being targeted. Further, various target materials expressed inside and outside of a cell membrane may be targeted, and thus even a type of cancer which is hard to diagnose such as triple negative breast cancer also be flexibly diagnosed. Further, using various fluorophores, multiple cancer may be diagnosed at the same time.
Owner:RES & BUSINESS FOUND SUNGKYUNKWAN UNIV

Polyolefin-based nanocomposite and preparation thereof

A polyolefin-based nanocomposite and a method of preparing the same are disclosed. The polyolefin-based nanocomposite is prepared by melt kneading a mixture including (A) 40-99.8% by weight of a matrix polymer of polyolefin; (B) 0.1-30% by weight of a polyolefin compatilizer containing polar reactive groups; and (C) 0.1-30% by weight of a layered clay material having a quaternary ammonium ion bonded to the surface thereof. The quaternary ammonium ion contains (I) at least one alkyl group having at least 15 carbon atoms; and (ii) a substitutent having —Si—O—Si—linkage and at least one terminal reactive group.
Owner:IND TECH RES INST
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