38 results about "Ionic strength" patented technology

The invention discloses a tooth repair composition containing mesoporous hydroxyapatite, a tooth repair product and a preparation method and application of the tooth repair composition and the tooth repair product. The tooth repair composition comprises nano-hydroxyapatite, fluoride and a chelating agent, the logarithm value logK of the stability constant K of the chelating agent to calcium ions is 1 < = logK < = 5, and K is measured in an aqueous solution with the temperature of 25 DEG C, the pH value of 7.0 and the ionic strength of 0.1 M; the nano-hydroxyapatite is prepared from nano-scale mesoporous hydroxyapatite, and the nano-hydroxyapatite contains nano-scale mesoporous hydroxyapatite. By adding the specific chelating agent, dynamic balance is formed in the tooth repairing composition, slow release protection can be formed on free calcium ions, the double inactivation effect possibly occurring when hydroxyapatite and fluoride exist at the same time is effectively avoided, the synergistic repairing effect of hydroxyapatite and fluoride is fully exerted, and the tooth repairing effect is improved. The use of fluorides can be greatly reduced, and safety and reliability are achieved.

This invention discloses a method for reducing the stability of amorphous calcium phosphate. The method involves adding an additive solution to an ACP solution; the additive is a calcium- and phosphorus-free inorganic salt that does not react with calcium ions and orthophosphate ions to form a precipitation reaction. This invention, by adding an inorganic salt after the formation of amorphous calcium phosphate, primarily increases the ionic strength of the solution, reduces calcium and phosphorus activity, promotes the dissolution of amorphous calcium phosphate, thereby altering its structure, significantly reducing its stability, and accelerating the formation of hydroxyapatite. Furthermore, this method uses low-cost raw materials, contributing to cost reduction.

Toner comprising a toner particle containing a binder resin, wherein the toner particle comprises a condensation product of an organosilicon compound, in time-of-flight secondary ion mass spectrometry (TOF-SIMS) of the toner particle, a normalized intensity of silicon ions (m / z 28) originating from the condensation product of the organosilicon compound, given by the following expression (I), of 7.00×10 -4 up to 3.00×10 -2 amounts; Normalized intensity λt of silicon ions (m / z 28) = {Ionic intensity λt (m / z 28) of silicon ions} / {Gesmation intensity λt from m / z 0.5 to 1850} a normalized intensity of silicon ions (m / z 28) by time-of-flight secondary ion mass spectrometry after sputtering the toner particles with an Ar-gas cluster ion beam Ar-GCIB under the following condition (A) 6.99×10 -4or less; (A) Acceleration voltage: 5 kV, Current: 6.5 nA, Grid size: 600×600 µm, Irradiation time: 5 seconds / cycle, Sputtering time: 250 seconds, the toner contains fine particles on the surface of the toner particles, and The fine particles of a polyvalent acid metal salt are a reaction product of a compound comprising at least one of the elements Ti and Al, and a polyvalent acid. wherein the condensation product of the organosilicon compound is a silane-modified resin R with the structure represented by the following formula (1); in formula (1) P 1 represents a styrene-acrylic resin segment or a polyester resin segment; L 1 represents a single bond or a divalent compound group; R 1 to R 3Each independently represents a hydrogen atom, a halogen atom, an alkyl group with 1 or more carbon atoms, an alkoxy group with 1 or more carbon atoms, an aryl group with 6 or more carbon atoms, or a hydroxy group; and m represents a positive integer; in a case where m is equal to or greater than 2, a plurality of L 1 , a plurality of R 1 , a plurality of R 2 and a plurality of R 3 each may be identical or different; however, Si is bonded to at least one carbon, and at least one of R 1 to R 3 is condensed with an organosilicon compound.

The invention belongs to the technical field of nylon 66 polymer performance testing, and particularly relates to a method for simultaneously testing the content of iodide ions and bromide ions in a nylon 66 polymer, which comprises the following steps of: extracting the iodide ions and the bromide ions in the polymer by using weak acid salt (sub-carbonate or bicarbonate) instead of potassium nitrate as an ionic strength regulator; the acid environment in the extracted solution is adjusted with formic acid, silver nitrate is adopted as a titrant, iodide ions and bromide ions in the extract liquor are detected at the same time through potentiometric titration, and the problem that the iodide ions and the bromide ions cannot be detected at the same time is solved.

An aqueous solution composition having a pH in the range of 4.0 to 8.5, comprising: an antibody construct comprising an Fc domain; optionally, one or more buffering agents which are a substance having at least one ionizable group, have a pKa in the range of 3.0 to 9.5, and have a pKa within 2 pH units of the pH of the composition; optionally, one or more neutral amino acids; and an uncharged tension regulator; wherein the total concentration of the buffer in the composition is 0-5 mM; and wherein the composition has a total ionic strength of less than 20 mM, excluding the contribution of engineered protein constructs.

The invention belongs to the technical field of stoichiometry, and discloses a nano-silver particle size standard substance and a preparation method thereof, the standard substance is composed of nano-silver particles, a stabilizer, a dispersion medium and a buffer system, the specific composition is as follows: the average particle size of the nano-silver particles is 40-60 nm, the particle size distribution standard deviation is less than 5 nm, and the nano-silver particles are spherical or torispherical; the stabilizer is selected from polyvinylpyrrolidone (PVP) or polyethylene glycol (PEG), the molecular weight of the stabilizer is 10 * 10 < 3 >-40 * 10 < 3 >, and the addition amount of the stabilizer is 5-10 times of the mass of silver; the dispersion medium is formed by mixing deionized water and absolute ethyl alcohol according to the volume ratio of (9: 1)-(8: 2), and the conductivity of the dispersion medium is lower than 1 mu S / cm; the buffer system adopts a boric acid-borax system, the pH is controlled between 8.0 and 9.0, and the buffer concentration is 5mmol / L to 10mmol / L, so that the ionic strength of the dispersion system and the surface potential stability of particles are maintained. And high controllability of the particle size and inter-batch repeatability are realized.

The invention relates to the field of biological materials, and provides an injectable hydrogel pre-gelatinizing solution based on ligand regulation and control and a preparation method and application of the injectable hydrogel pre-gelatinizing solution. A multivalent metal ion; a small molecule ligand; wherein the alginic acid compound comprises alginic acid or alginate and a derivative thereof; the molar ratio of the micromolecule ligand to the multivalent metal ions is marked as L / M; defining the minimum L / M for keeping the system in a sol state at the set temperature and ion strength as a critical ligand ratio, and recording the critical ligand ratio as CLR; in the pre-gelatinizing solution, L / M is greater than or equal to CLR. The pre-gelatinizing solution can be smoothly injected through a fine needle, can quickly form a gel shell at an interface to prevent leakage after being injected to a water-containing environment, has continuous self-enhancement performance, and is wide in application range.

This invention provides zinc phthalocyanine polyhalogenate, which contributes to improving the brightness of color filters. [Solution] A zinc phthalocyanine polyhalide comprising a compound represented by the following general formula (i), wherein, in the mass spectrum obtained by matrix-assisted laser desorption / ionization time-of-flight mass spectrometry, when the maximum ionic intensity in the range of m / z 1820 to 1860 is denoted as I1 and the maximum ionic intensity in the range of m / z 1740 to less than 1780 is denoted as I2, the ratio I2 / I1 is 0.50 or less. TIFF2026086779000008.tif68149

An aqueous solution composition of pH in the range 4.0-8.5 comprising:an antibody construct comprising an Fc domain;optionally one or more buffers being substances having at least one ionisable group with a pKa in the range 3.0 to 9.5 and which pKa is within 2 pH units of the pH of the composition;optionally one or more neutral amino acids; andan uncharged tonicity modifier;wherein the buffers are present in the composition at a total concentration of 0-5 mM; andwherein the total ionic strength of the composition excluding the contribution of the engineered protein construct is less than 20 mM.

The invention relates to the technical field of irrigation, and discloses a coastal wetland plant maintenance system and method.The method comprises the steps that firstly, concentration spatial distribution of thiosulfate and tetrathiosulfate in a root domain is obtained, the spatial position and the peak shape curvature of a concentration ratio peak are determined based on the concentration spatial distribution, and meanwhile the outer edge spatial position of a root surface iron plaque is determined; calculating position deviation and curvature deviation between the two; further measuring the root domain volume and the ion strength and sulfate radical concentration of pore water; then, a small amount of fresh water and brackish water are injected into the root domain, the spatial position of a concentration ratio peak and the change rate of curvature are observed, and the hydrochemistry and root domain reaction relation is established; according to the deviation and the change rate, the required ion strength and the sulfate radical concentration adjustment amount are solved, the volume of fresh water and the volume of brackish water required by single-time maintenance are accurately converted according to the root domain volume and the ion characteristics of different water sources, and therefore scientific regulation and control over the coastal wetland plant root domain environment are achieved.

The invention discloses a sample pretreatment method and a determination method for detecting the total sulfur dioxide content in a spice matrix, and the method comprises the following steps: adding a surfactant and an antioxidant into an aqueous dispersion of a spice matrix sample, and then carrying out stepped temperature control heat treatment under an alkaline condition; and adding inorganic salt into the obtained liquid phase to enhance the ionic strength, extracting and purifying to finish the pretreatment process for subsequent detection of the total sulfur dioxide content. According to the method, the pretreatment process is effectively improved, the total sulfur dioxide in the matrix is effectively and accurately enriched through catalytic liberation and in-situ protection of the combined sulfur dioxide in the spice matrix and by combining the dual means of salting-out anchoring and physical purification, the problem of multiple interferences existing in an existing pretreatment means is systematically solved, and the method is suitable for large-scale popularization and application. And finally, rapid, accurate and reliable determination of the total sulfur dioxide in the spice matrix is realized.

The application belongs to the technical field of electrochemical analysis and test, and discloses a chlorine ion probe calibration method based on selective coefficient correction. The method calibrates the main standard under the same ion intensity and temperature conditions as the sample, measures the selective coefficient of Br⁻ and I⁻, uses the extended potential-activity relationship to analyze and correct the interference, and obtains the accurate chlorine ion activity / concentration. The application is suitable for seawater, brine and other complex media, and significantly improves the accuracy, repeatability and traceability of measurement.

The invention relates to a method for removing iron and aluminum impurities in strong acid liquid, and belongs to the field of hydrometallurgy and resource utilization. The method specifically comprises the following steps: adding manganese monoxide powder (MnO) into a strongly acidic aqueous solution containing iron and aluminum, and gradually adjusting the acidity of the system under a mild condition, so that iron and aluminum ions form insoluble precipitates; after solid-liquid separation and washing, the removal rate of iron and aluminum exceeds 90%, and the loss of target elements such as magnesium and lithium is small. According to the method, introduction of exogenous sodium salt is avoided, the ionic strength shielding effect caused by strong electrolyte such as NaCl is effectively avoided, a recessive chlorine salt buffer system is prevented from being formed, and it is ensured that pH adjustment is more flexible and controllable. The method is suitable for pretreatment processes of various acidic industrial liquids such as titanium slag water quenching liquid and lepidolite pickle liquor. The method has the advantages of low raw material cost, large precipitate particles, easiness in filtration, mild operation conditions and the like, and is suitable for industrial-scale application and popularization.

The invention relates to the technical field of grinding and polishing, in particular to a sapphire polishing solution as well as a preparation method and application thereof. The sapphire polishing solution comprises the following components in parts by weight: 20-30 wt% of alumina powder, 0.1-1 wt% of a dispersing agent, 0.01-1 wt% of a suspension additive, 1-10 wt% of a pH regulator, 0.1-3 wt% of a lubricant and the balance of water, the suspension auxiliary agent is selected from one or more of nonionic cellulose ether and polysaccharide with rigid double-helix, low-charge and acetyl-free structural characteristics. The grinding particles of the sapphire polishing solution are excellent in suspension performance and high in dispersion stability under strong base and high ionic strength; the sapphire wafer polishing solution has high polishing removal efficiency and excellent surface quality (low roughness Ra) on sapphire wafers under the conditions of strong base and high ionic strength.

The invention provides a chromatographic method for separating pre-contraction state PVC Nanosyringes from post-contraction state PVC Nanosyringes, the method comprising: (a) providing a sample containing both pre- and post-contraction state PVC Nanosyringes; (b) loading the sample on a monolith anion exchange column having (preferably quaternary amine) binding moieties, under conditions (e.g. pH 7-8, temperature 19-25°C) wherein pre- and post-contraction state PVC Nanosyringes become bound to the column with differing affinities; (c) applying a gradient of ionic strength to the column that provides for differential elution of the pre- and post-contraction state PVC Nanosyringes, wherein the gradient is generated by incrementally (e.g. linearly) increasing the salt concentration of a mobile phase elution buffer that is applied to the column; and (d) eluting the pre- and post-contraction state PVC Nanosyringes into separate elution fractions under the gradient based on their differing affinities to the anion exchange column, and collecting fractions having the pre-contraction state PVC Nanosyringes separated from the post-contraction state PVC Nanosyringes.

The invention relates to the technical field of disinfectants, and discloses a controllable slow-release peracetic acid disinfectant and a preparation process thereof, and the disinfectant is prepared from peracetic acid equilibrium liquid, boric acid, polyol, polyaspartic acid solution and other raw materials. The structure is characterized in that peroxyacetic acid and boric acid form a reversible complex, and the reversible complex is dispersed in a continuous phase matrix with polyol as a main body as a dispersion phase. The preparation process adopts a step-by-step heterogeneous compounding method, and comprises the following steps: firstly, independently preparing an activation complexing solution containing a peracetic acid-boric acid complex; then independently preparing a matrix solution containing polyhydric alcohol and polyaspartic acid; and finally, dispersing the activated complexing solution into a matrix solution under the shearing action, curing and adjusting the pH value to obtain a final product. The process avoids the loss of active matters in the preparation process. The disinfectant has the advantages that the storage stability is high, the active matter can be continuously and slowly released, and the release rate has environmental ion strength responsiveness.

An aqueous composition having a pH in the range of 4.0–8.5, comprising: an antibody construct containing an Fc domain; optionally, one or more buffers having at least one ionizable group and a pK value in the range of 3.0 to 9.5. a And its PK a Within 2 pH units of the pH of the composition; optionally, one or more neutral amino acids; and an uncharged tension modifier; wherein the total concentration of the buffer in the composition is 0-5 mM; and wherein the total ionic strength of the composition is less than 20 mM, excluding the contribution of engineered protein constructs.

The application belongs to the technical field of medicine extraction and medicine detection, and discloses a detection method of related substances in palonosetron-containing fat emulsion injection. Methanol is used as a main demulsifier, and a sodium dihydrogen phosphate buffer salt solution with a suitable ionic strength is used for assistance, so that full demulsification is realized under the premise of not introducing a third organic phase; a water bath evaporation and redissolution method is used to enrich target components in the solution after demulsification, so that good chromatographic behavior and complete recovery of the target components are ensured, and the detection sensitivity is effectively improved. The palonosetron and related impurities have good separation degree, the method is simple to operate, accurate to measure, and strong in specificity, and is suitable for the determination of palonosetron related substances in rolapitant palonosetron fat emulsion.

The embodiment of the invention discloses a low-zeta-potential standard working liquid as well as a preparation method and application thereof, and belongs to the technical field of metrology and colloidal chemistry. The low zeta potential standard working liquid comprises a suspension liquid a and an ionic liquid b which are independently subpackaged and stored, and the zeta potential value of the suspension liquid a is + 30 mV to + 50 mV; the ionic liquid b contains Na < + > and / or K < + >, and the total ionic strength is 100-200 mmol.L <-1 >; the volume ratio of the suspension liquid a to the ionic liquid b is 1: (4-9). According to the invention, the problem that the low zeta potential standard substance is easy to flocculate and lose stability is solved through a mode of combining double-liquid independent subpackage preservation (zeta preservation) and instantaneous separation intensity regulation (zeta regulation), and long-term stable storage and high reproducibility are realized; the method has a wide application prospect in research and quality control of low surface charge systems related to nano medicines, biological materials, environmental colloids, food emulsions and the like.

The invention discloses a method for extracting gastrodia elata phenolic compounds by an ionic strength response type deep-eutectic solvent mediated aqueous two-phase system, which comprises the following steps: mixing gastrodia elata powder with a deep-eutectic solvent, and carrying out ultrasonic extraction to obtain a DES extracting solution containing the gastrodia elata phenolic compounds; mixing and stirring the DES extracting solution and a K3PO4 solution, and centrifuging to obtain a DES-rich top phase and a salt-rich bottom phase; mixing and stirring the DES-rich top phase and a KH2PO4 solution, and centrifuging to obtain supernatant and precipitate rich in gastrodia elata phenolic compounds; and adding water into the obtained precipitate to realize regeneration of the eutectic solvent, and circularly applying the eutectic solvent to ultrasonic extraction. According to the method, efficient enrichment, separation and purification of gastrodia elata phenolic substances and recovery and reuse of DES can be synchronously achieved through the ionic strength response type eutectic solvent mediated aqueous two-phase system, the process is simple, operation is mild, and the method is suitable for industrial application.

This application relates to a low-alpha-ray silica and its preparation method. The method involves adding a high-purity sodium sulfate solution to water glass, followed by the sequential addition of dilute sulfuric acid solutions of varying concentrations for aging. The resulting precipitate is then calcined to obtain low-alpha-ray silica with Th ≤ 5 ppb and U ≤ 5 ppb. The sodium sulfate solution optimizes the precipitation process in two ways: first, it increases the ionic strength of the solution, compresses the colloidal double layer, and disrupts the metastable state of the system, thus promoting the aggregation and crystallization of the target precipitate; second, sulfate ions preferentially complex or inhibit the precipitation tendency of impurity cations based on the common ion effect; furthermore, the dilute sulfuric acid solution promotes the reaction and rapid precipitation of silicate ions with hydrogen ions, causing the Th and U ions encapsulated in the precipitate to precipitate out, thereby reducing the impurity content in the solution. This low-alpha-ray silica, due to its extremely low Th and U content and good thermal conductivity, can be widely used in high-performance and special-purpose chip packaging fields.

The invention belongs to the technical field of electrochemical analysis and testing, and discloses a chloride ion probe calibration method based on selectivity coefficient correction. According to the method, main calibration is carried out under the condition that the ionic strength and temperature are consistent with those of a sample, the selectivity coefficient to Br and I is measured, interference is analyzed and corrected by utilizing the expansion potential-activity relation, and the accurate chloride ion activity / concentration is obtained. The method is suitable for complex media such as seawater and brine, and the accuracy, repeatability and traceability of measurement are remarkably improved.

The present disclosure pertains to methods of separating nucleic acid component compounds from one another. In some embodiments, the methods comprise: (a) loading a sample fluid comprising a plurality of nucleic acid component compounds onto a chromatographic column comprising a zwitterionic stationary phase contained inside the column; (b) flowing a mobile phase through the chromatographic column over a time period thereby forming an eluent in which at least some of the plurality of the nucleic acid component compounds are separated from each other, the mobile phase comprising a polar aprotic solvent, a protic solvent, and a volatile buffer salt, wherein flowing the mobile phase comprises varying a ratio of the protic solvent to the polar aprotic solvent over at least a portion of the time period and varying an ionic strength of the volatile buffer salt over at least a portion of the time period.

The invention relates to the technical field of mine safety and dust prevention and control, and discloses high-stability dust suppression foam based on the ion in-situ shielding effect and a construction technology thereof.The foam is prepared from a coalescing agent, a surfactant, an ion shielding agent and a hard water solvent. The preparation method comprises the following steps: preparing a film forming aid solution, compounding a basic foaming solution, adding an ion shielding agent, carrying out continuous suspension treatment and interface reconstruction, and finally carrying out physical foaming to prepare the gas-liquid-solid interface film, wherein the basic foaming solution, the film forming aid solution and the surfactant are cooperated to construct the stable gas-liquid-solid interface film, and the preparation method comprises the following steps: preparing the film forming aid solution, compounding the basic foaming solution, adding the ion shielding agent, carrying out continuous suspension treatment and interface reconstruction, and finally carrying out physical foaming. The problems of poor foam stability and low dust suppression efficiency caused by mine high-hardness water quality are effectively solved, and the obtained foam is low in surface tension, long in drainage half-life period, high in coal dust wetting speed and suitable for a mine high-salinity water quality environment.

The application discloses a preparation method of hyaluronic acid chlorhexidine with bacteriostatic effect, and comprises the following steps: S1) preparing a sodium hyaluronate solution with a mass fraction of 2-3%; S2) preparing a chlorhexidine digluconate solution with a mass fraction of 1-2%; S3) slowly adding the chlorhexidine digluconate solution in the step S2) into the sodium hyaluronate solution in the step S1) and stirring to react; S4) adding anhydrous ethanol pre-cooled to 4 DEG C into the reaction mixture and standing to precipitate; S5) filtering the precipitate by using a filter membrane and repeatedly washing the precipitate with ethanol solutions with volume ratios of 75%, 85% and 95% for 3-5 times in sequence; and S6) drying the obtained precipitate for 8-12 hours to obtain hyaluronic acid chlorhexidine. The application adopts specific process parameters and reaction conditions, controls the reaction temperature, pH value and ionic strength accurately, and combines the synergistic effect of mechanical stirring and magnetic stirring, so that the uniformity and controllability of the reaction are remarkably improved, and the grafting rate of the hyaluronic acid chlorhexidine product prepared by the method can reach more than 85%.

The invention discloses a method for testing and evaluating carbonate dissolved and weathered carbon sinks, which comprises the following steps of: acquiring and preprocessing multi-source data, constructing a carbonate rock exposure mask, establishing a soil carbon dioxide partial pressure multivariable estimation model, and calibrating an observation data area of water-containing chemical and equilibrium information to obtain gridded soil carbon dioxide partial pressure distribution; the dynamic ion strength and the corrected ion activity coefficient are calculated in combination with hydrological process and hydrochemical data, the maximum potential carbonate dissolution rate is solved and converted into the carbonate dissolution and weathering carbon sink amount, a comprehensive carbon sink index representing the carbon sink capacity and stability is constructed, and a carbon sink enhanced hot spot area and a sensitive response zone are identified. According to the method, the contribution of various external forces such as quantitative separation of greenhouse gases, natural force, aerosol, land utilization and the like to carbonate dissolved-weathered carbon convergence is provided, and a new tool is provided for carbon cycle response evaluation in future climate scenarios.

A method for measuring a creatinine correction value of a nucleoside according to the present disclosure includes a step (S10) for temporally separating a component, a step (S12) for acquiring a chromatogram of an ion derived from each component, a step (S14) for acquiring a nucleoside measurement value on the basis of a chromatogram of an ion of the nucleoside, a step (S16) for acquiring a creatinine measurement value on the basis of a chromatogram of a product ion other than the product ion having the highest ionic strength of creatinine, and a step (S18) for calculating a creatinine correction value of the nucleoside.

This invention discloses the preparation and application of an iron-based nitrogen-doped carbonaceous material with carbonic anhydrase-like activity. The invention employs a co-precipitation method and a high-temperature carbonization method to prepare the material Fe10@CN-Mg, in which most of the iron is uniformly distributed in the form of single atoms on the nitrogen-doped carbon, wherein FeN... x The synergistic catalytic effect of the active site and Mg(OH)2 nanorods exhibits carbonic anhydrase-like activity. This material has a low metal content and low preparation cost, yet it still possesses kinetic constants comparable to other reported CA-like nanozymes and an excellent CaCO3 formation rate. It also demonstrates excellent stability even under extreme pH, high temperature, organic solvents, and high ionic strength conditions, maintaining high activity even after long-term storage and multiple recycling. Therefore, it can be applied to catalyze the conversion of CO2 to cyclic carbonates with biological and pharmaceutical applications.

The invention belongs to the technical field of graphene preparation, and particularly relates to an intercalator for graphene preparation and a preparation method and application thereof. The preparation method of the intercalator for graphene preparation comprises the following steps: (1) providing a sodium cholate aqueous solution as a basic solution; (2) adding a microenvironment regulating agent into the basic solution, and regulating and stabilizing the pH value and / or ionic strength I of the system to a preset target value; (3) dropwise adding an aqueous solution containing calcium ions into the solution obtained in the step (2) under the conditions of continuous stirring and temperature control, and controlling the final molar concentration ratio R of the calcium ions to the sodium cholate to a preset value; and (4) curing the mixed solution obtained in the step (3) at a set temperature to obtain the intercalator for graphene preparation. The intercalator system provided by the invention has definite environmental response and self-adaptive characteristics, and is beneficial to obtaining graphene with narrow layer number distribution and high quality when being used for preparing graphene.