64 results about "Ionic strength" patented technology

The invention discloses a tooth repair composition containing mesoporous hydroxyapatite, a tooth repair product and a preparation method and application of the tooth repair composition and the tooth repair product. The tooth repair composition comprises nano-hydroxyapatite, fluoride and a chelating agent, the logarithm value logK of the stability constant K of the chelating agent to calcium ions is 1 < = logK < = 5, and K is measured in an aqueous solution with the temperature of 25 DEG C, the pH value of 7.0 and the ionic strength of 0.1 M; the nano-hydroxyapatite is prepared from nano-scale mesoporous hydroxyapatite, and the nano-hydroxyapatite contains nano-scale mesoporous hydroxyapatite. By adding the specific chelating agent, dynamic balance is formed in the tooth repairing composition, slow release protection can be formed on free calcium ions, the double inactivation effect possibly occurring when hydroxyapatite and fluoride exist at the same time is effectively avoided, the synergistic repairing effect of hydroxyapatite and fluoride is fully exerted, and the tooth repairing effect is improved. The use of fluorides can be greatly reduced, and safety and reliability are achieved.

The invention provides an engineered nuclease with high salt tolerance. The polypeptide comprises one or more mutations, so that the three-dimensional structure of the polypeptide has more surface areas with positive charges. Compared with the nuclease with the SEQ ID NO: 1 sequence, the polypeptide still has at least 60% nuclease activity under the condition that the solution ion strength exceeds 200 mM.

The invention belongs to the technical field of natural active collagen, and particularly relates to a method for rapidly detecting the content of active collagen. According to the method, a collagen reference substance with a complete triple helix structure and denatured collagen losing the triple helix structure after denaturation treatment are mixed according to different proportions, a series of standard samples with different triple helix structure contents are prepared, and the content of active collagen is detected by utilizing self-assembly performance characterization. The method comprises the following steps: adding a PBS (Phosphate Buffer Solution) into a collagen solution, carrying out in-vitro self-assembly under proper conditions (cooperative control of collagen concentration, pH value, ion strength, temperature and the like), and determining the turbidity change of the collagen solution in real time under a set wavelength to obtain a quantitative standard curve for calculating the content of active collagen in a test sample. The method for detecting the content of the active collagen is quicker, simpler and more convenient, and compared with a traditional protease enzymolysis method, the detection time is greatly shortened, and the detection efficiency is also improved.

This invention discloses a method for reducing the stability of amorphous calcium phosphate. The method involves adding an additive solution to an ACP solution; the additive is a calcium- and phosphorus-free inorganic salt that does not react with calcium ions and orthophosphate ions to form a precipitation reaction. This invention, by adding an inorganic salt after the formation of amorphous calcium phosphate, primarily increases the ionic strength of the solution, reduces calcium and phosphorus activity, promotes the dissolution of amorphous calcium phosphate, thereby altering its structure, significantly reducing its stability, and accelerating the formation of hydroxyapatite. Furthermore, this method uses low-cost raw materials, contributing to cost reduction.

Toner comprising a toner particle containing a binder resin, wherein the toner particle comprises a condensation product of an organosilicon compound, in time-of-flight secondary ion mass spectrometry (TOF-SIMS) of the toner particle, a normalized intensity of silicon ions (m / z 28) originating from the condensation product of the organosilicon compound, given by the following expression (I), of 7.00×10 -4 up to 3.00×10 -2 amounts; Normalized intensity λt of silicon ions (m / z 28) = {Ionic intensity λt (m / z 28) of silicon ions} / {Gesmation intensity λt from m / z 0.5 to 1850} a normalized intensity of silicon ions (m / z 28) by time-of-flight secondary ion mass spectrometry after sputtering the toner particles with an Ar-gas cluster ion beam Ar-GCIB under the following condition (A) 6.99×10 -4or less; (A) Acceleration voltage: 5 kV, Current: 6.5 nA, Grid size: 600×600 µm, Irradiation time: 5 seconds / cycle, Sputtering time: 250 seconds, the toner contains fine particles on the surface of the toner particles, and The fine particles of a polyvalent acid metal salt are a reaction product of a compound comprising at least one of the elements Ti and Al, and a polyvalent acid. wherein the condensation product of the organosilicon compound is a silane-modified resin R with the structure represented by the following formula (1); in formula (1) P 1 represents a styrene-acrylic resin segment or a polyester resin segment; L 1 represents a single bond or a divalent compound group; R 1 to R 3Each independently represents a hydrogen atom, a halogen atom, an alkyl group with 1 or more carbon atoms, an alkoxy group with 1 or more carbon atoms, an aryl group with 6 or more carbon atoms, or a hydroxy group; and m represents a positive integer; in a case where m is equal to or greater than 2, a plurality of L 1 , a plurality of R 1 , a plurality of R 2 and a plurality of R 3 each may be identical or different; however, Si is bonded to at least one carbon, and at least one of R 1 to R 3 is condensed with an organosilicon compound.

The invention belongs to the technical field of nylon 66 polymer performance testing, and particularly relates to a method for simultaneously testing the content of iodide ions and bromide ions in a nylon 66 polymer, which comprises the following steps of: extracting the iodide ions and the bromide ions in the polymer by using weak acid salt (sub-carbonate or bicarbonate) instead of potassium nitrate as an ionic strength regulator; the acid environment in the extracted solution is adjusted with formic acid, silver nitrate is adopted as a titrant, iodide ions and bromide ions in the extract liquor are detected at the same time through potentiometric titration, and the problem that the iodide ions and the bromide ions cannot be detected at the same time is solved.

An aqueous solution composition having a pH in the range of 4.0 to 8.5, comprising: an antibody construct comprising an Fc domain; optionally, one or more buffering agents which are a substance having at least one ionizable group, have a pKa in the range of 3.0 to 9.5, and have a pKa within 2 pH units of the pH of the composition; optionally, one or more neutral amino acids; and an uncharged tension regulator; wherein the total concentration of the buffer in the composition is 0-5 mM; and wherein the composition has a total ionic strength of less than 20 mM, excluding the contribution of engineered protein constructs.

The invention belongs to the technical field of stoichiometry, and discloses a nano-silver particle size standard substance and a preparation method thereof, the standard substance is composed of nano-silver particles, a stabilizer, a dispersion medium and a buffer system, the specific composition is as follows: the average particle size of the nano-silver particles is 40-60 nm, the particle size distribution standard deviation is less than 5 nm, and the nano-silver particles are spherical or torispherical; the stabilizer is selected from polyvinylpyrrolidone (PVP) or polyethylene glycol (PEG), the molecular weight of the stabilizer is 10 * 10 < 3 >-40 * 10 < 3 >, and the addition amount of the stabilizer is 5-10 times of the mass of silver; the dispersion medium is formed by mixing deionized water and absolute ethyl alcohol according to the volume ratio of (9: 1)-(8: 2), and the conductivity of the dispersion medium is lower than 1 mu S / cm; the buffer system adopts a boric acid-borax system, the pH is controlled between 8.0 and 9.0, and the buffer concentration is 5mmol / L to 10mmol / L, so that the ionic strength of the dispersion system and the surface potential stability of particles are maintained. And high controllability of the particle size and inter-batch repeatability are realized.

The invention relates to the field of biological materials, and provides an injectable hydrogel pre-gelatinizing solution based on ligand regulation and control and a preparation method and application of the injectable hydrogel pre-gelatinizing solution. A multivalent metal ion; a small molecule ligand; wherein the alginic acid compound comprises alginic acid or alginate and a derivative thereof; the molar ratio of the micromolecule ligand to the multivalent metal ions is marked as L / M; defining the minimum L / M for keeping the system in a sol state at the set temperature and ion strength as a critical ligand ratio, and recording the critical ligand ratio as CLR; in the pre-gelatinizing solution, L / M is greater than or equal to CLR. The pre-gelatinizing solution can be smoothly injected through a fine needle, can quickly form a gel shell at an interface to prevent leakage after being injected to a water-containing environment, has continuous self-enhancement performance, and is wide in application range.

The present invention discloses a C-doped TiO2 material and its preparation method and application, which belongs to the technical field of material preparation and deep water purification. Using titanium-based metal organic gel (Ti-MOG) as a template, a high-temperature calcination method is used to obtain a TiO2 material with a microporous-mesoporous multi-level pore structure, highly dispersed TiO2 active sites, an ultra-thin C layer coating, and a Ti-containing 3+ A C-doped TiO2 material with a high adsorption-photocatalytic degradation rate of MCs in water, characterized by a high ionic strength (V / V) and anatase TiO2 heterojunction, is prepared by ultrasonically dissolving terephthalic acid in a mixture of DMF and methanol in a certain proportion; adding concentrated hydrochloric acid and tetrabutyl titanate in a certain proportion and stirring; reacting in an autoclave at a certain temperature for a period of time to obtain a Ti-MOG wet gel; washing the wet gel with an organic solvent; drying the wet gel, and then calcining it at a certain temperature. This material is highly effective in the adsorption-photocatalytic degradation of trace organic pollutants in water, with a wide light response range.

This invention provides zinc phthalocyanine polyhalogenate, which contributes to improving the brightness of color filters. [Solution] A zinc phthalocyanine polyhalide comprising a compound represented by the following general formula (i), wherein, in the mass spectrum obtained by matrix-assisted laser desorption / ionization time-of-flight mass spectrometry, when the maximum ionic intensity in the range of m / z 1820 to 1860 is denoted as I1 and the maximum ionic intensity in the range of m / z 1740 to less than 1780 is denoted as I2, the ratio I2 / I1 is 0.50 or less. TIFF2026086779000008.tif68149

The present application provides a method for testing the swelling degree of carbomer gel. By testing the swelling degree of carbomer gel in the same electrolyte and solvents with different concentrations, the first swelling degree corresponding to each selected sol is obtained; based on all the first swelling degrees, the contribution degree of the hydrophilicity of carbomer gel to the change in swelling degree is determined; the swelling degree of carbomer gel is tested in different electrolytes and solvents with different concentrations to obtain the second swelling degree corresponding to each selected sol; based on all the second swelling degrees, the amount of solvent wrapped by the molecular chains in carbomer gel under unit ionic strength is determined; according to the contribution degree and the wrapped amount, the swelling responsiveness of the swelling degree of carbomer gel to the change in ionic strength in the solvent is determined, and the swelling degree test result is generated based on the swelling responsiveness. By adopting the solution of the present application, a transfer relationship between the swelling degree of carbomer gel and the ionic strength in the solvent can be established, thereby improving the versatility of the swelling degree test result of carbomer gel.

An aqueous solution composition of pH in the range 4.0-8.5 comprising:an antibody construct comprising an Fc domain;optionally one or more buffers being substances having at least one ionisable group with a pKa in the range 3.0 to 9.5 and which pKa is within 2 pH units of the pH of the composition;optionally one or more neutral amino acids; andan uncharged tonicity modifier;wherein the buffers are present in the composition at a total concentration of 0-5 mM; andwherein the total ionic strength of the composition excluding the contribution of the engineered protein construct is less than 20 mM.

The invention discloses a method for calculating the conductivity of a supercritical geothermal fluid system KCl-H2O, which relates to the technical field of new energy, and comprises the following steps: acquiring basic parameters of system temperature, ionic strength, dielectric constant and water density, and constructing a total conductivity expression according to the parameters to calculate the conductivity. According to the method, a Shedlovsky correction model is introduced to be combined with a step-by-step dilution method, experimental data are extrapolated to infinite dilution conditions, then the quantitative relation between the limit molar conductivity of KCl and temperature and pressure is obtained, a Watson viscosity model and crystallographic ion radius parameters are introduced, a high-temperature and high-pressure diffusion coefficient calculation formula is corrected, the prediction error of the diffusion coefficients of K + and Cl-is reduced to be within + / -5%, and the prediction accuracy of the KCl-diffusion coefficient is improved. The coupling rule of the activity coefficient and the diffusion coefficient at high temperature and high pressure is disclosed by synchronously measuring the activity coefficient and the diffusion coefficient, and key parameter support is provided for an earth deep fluid evolution model.

The objective of the present invention is to improve the heat resistance of a nanoemulsion-containing composition having an ionic strength of 0.02 to 5 mol / L and containing 0.01 to 5 mass % of an oil-in-water nanoemulsion with an emulsified particle size of 100 nm or less as the oil phase. To the aqueous phase of a nanoemulsion-containing composition that satisfies the following requirements (A) and (B), one or more selected from enzyme-treated lecithin, organic acid monoglyceride, and ascorbic acid fatty acid ester are added in an amount of 0.1 to 20 times by mass relative to the oil phase of the oil-in-water nanoemulsion of (A). (A) 0.01 to 5% by mass of an oil-in-water nanoemulsion with an emulsified particle size of 100 nm or less as the oil phase (B) Ionic strength is 0.02 to 5 mol / L

The invention relates to the technical field of irrigation, and discloses a coastal wetland plant maintenance system and method.The method comprises the steps that firstly, concentration spatial distribution of thiosulfate and tetrathiosulfate in a root domain is obtained, the spatial position and the peak shape curvature of a concentration ratio peak are determined based on the concentration spatial distribution, and meanwhile the outer edge spatial position of a root surface iron plaque is determined; calculating position deviation and curvature deviation between the two; further measuring the root domain volume and the ion strength and sulfate radical concentration of pore water; then, a small amount of fresh water and brackish water are injected into the root domain, the spatial position of a concentration ratio peak and the change rate of curvature are observed, and the hydrochemistry and root domain reaction relation is established; according to the deviation and the change rate, the required ion strength and the sulfate radical concentration adjustment amount are solved, the volume of fresh water and the volume of brackish water required by single-time maintenance are accurately converted according to the root domain volume and the ion characteristics of different water sources, and therefore scientific regulation and control over the coastal wetland plant root domain environment are achieved.

The invention belongs to the technical field of industrial water analysis of copper smelting enterprises, and particularly relates to a method for measuring the content of chloride ions in production wastewater. The method comprises the following steps: adding an ionic strength regulator into a sample to maintain constant ionic strength, preparing a series of chloride ion standard solutions, measuring the potential value of chloride ions by using an ion meter, and making a standard working curve by using the negative logarithm of the chloride ion concentration as a horizontal coordinate and the potential value as a vertical coordinate; and checking the chlorine content in the standard working curve according to the potential value of the sample. The method has the beneficial effects that compared with a silver nitrate titration method, the ion selective electrode method for measuring the production wastewater is higher in accuracy and precision, less in interference and high in analysis speed. Poisonous and harmful reagents are prevented from harming the health of workers and the environment, and accurate and reliable instructive data can be provided in actual production.

The invention discloses a sample pretreatment method and a determination method for detecting the total sulfur dioxide content in a spice matrix, and the method comprises the following steps: adding a surfactant and an antioxidant into an aqueous dispersion of a spice matrix sample, and then carrying out stepped temperature control heat treatment under an alkaline condition; and adding inorganic salt into the obtained liquid phase to enhance the ionic strength, extracting and purifying to finish the pretreatment process for subsequent detection of the total sulfur dioxide content. According to the method, the pretreatment process is effectively improved, the total sulfur dioxide in the matrix is effectively and accurately enriched through catalytic liberation and in-situ protection of the combined sulfur dioxide in the spice matrix and by combining the dual means of salting-out anchoring and physical purification, the problem of multiple interferences existing in an existing pretreatment means is systematically solved, and the method is suitable for large-scale popularization and application. And finally, rapid, accurate and reliable determination of the total sulfur dioxide in the spice matrix is realized.

The application belongs to the technical field of electrochemical analysis and test, and discloses a chlorine ion probe calibration method based on selective coefficient correction. The method calibrates the main standard under the same ion intensity and temperature conditions as the sample, measures the selective coefficient of Br⁻ and I⁻, uses the extended potential-activity relationship to analyze and correct the interference, and obtains the accurate chlorine ion activity / concentration. The application is suitable for seawater, brine and other complex media, and significantly improves the accuracy, repeatability and traceability of measurement.

The invention relates to a method for removing iron and aluminum impurities in strong acid liquid, and belongs to the field of hydrometallurgy and resource utilization. The method specifically comprises the following steps: adding manganese monoxide powder (MnO) into a strongly acidic aqueous solution containing iron and aluminum, and gradually adjusting the acidity of the system under a mild condition, so that iron and aluminum ions form insoluble precipitates; after solid-liquid separation and washing, the removal rate of iron and aluminum exceeds 90%, and the loss of target elements such as magnesium and lithium is small. According to the method, introduction of exogenous sodium salt is avoided, the ionic strength shielding effect caused by strong electrolyte such as NaCl is effectively avoided, a recessive chlorine salt buffer system is prevented from being formed, and it is ensured that pH adjustment is more flexible and controllable. The method is suitable for pretreatment processes of various acidic industrial liquids such as titanium slag water quenching liquid and lepidolite pickle liquor. The method has the advantages of low raw material cost, large precipitate particles, easiness in filtration, mild operation conditions and the like, and is suitable for industrial-scale application and popularization.

The invention relates to the technical field of grinding and polishing, in particular to a sapphire polishing solution as well as a preparation method and application thereof. The sapphire polishing solution comprises the following components in parts by weight: 20-30 wt% of alumina powder, 0.1-1 wt% of a dispersing agent, 0.01-1 wt% of a suspension additive, 1-10 wt% of a pH regulator, 0.1-3 wt% of a lubricant and the balance of water, the suspension auxiliary agent is selected from one or more of nonionic cellulose ether and polysaccharide with rigid double-helix, low-charge and acetyl-free structural characteristics. The grinding particles of the sapphire polishing solution are excellent in suspension performance and high in dispersion stability under strong base and high ionic strength; the sapphire wafer polishing solution has high polishing removal efficiency and excellent surface quality (low roughness Ra) on sapphire wafers under the conditions of strong base and high ionic strength.

The invention provides a chromatographic method for separating pre-contraction state PVC Nanosyringes from post-contraction state PVC Nanosyringes, the method comprising: (a) providing a sample containing both pre- and post-contraction state PVC Nanosyringes; (b) loading the sample on a monolith anion exchange column having (preferably quaternary amine) binding moieties, under conditions (e.g. pH 7-8, temperature 19-25°C) wherein pre- and post-contraction state PVC Nanosyringes become bound to the column with differing affinities; (c) applying a gradient of ionic strength to the column that provides for differential elution of the pre- and post-contraction state PVC Nanosyringes, wherein the gradient is generated by incrementally (e.g. linearly) increasing the salt concentration of a mobile phase elution buffer that is applied to the column; and (d) eluting the pre- and post-contraction state PVC Nanosyringes into separate elution fractions under the gradient based on their differing affinities to the anion exchange column, and collecting fractions having the pre-contraction state PVC Nanosyringes separated from the post-contraction state PVC Nanosyringes.

The invention relates to the technical field of disinfectants, and discloses a controllable slow-release peracetic acid disinfectant and a preparation process thereof, and the disinfectant is prepared from peracetic acid equilibrium liquid, boric acid, polyol, polyaspartic acid solution and other raw materials. The structure is characterized in that peroxyacetic acid and boric acid form a reversible complex, and the reversible complex is dispersed in a continuous phase matrix with polyol as a main body as a dispersion phase. The preparation process adopts a step-by-step heterogeneous compounding method, and comprises the following steps: firstly, independently preparing an activation complexing solution containing a peracetic acid-boric acid complex; then independently preparing a matrix solution containing polyhydric alcohol and polyaspartic acid; and finally, dispersing the activated complexing solution into a matrix solution under the shearing action, curing and adjusting the pH value to obtain a final product. The process avoids the loss of active matters in the preparation process. The disinfectant has the advantages that the storage stability is high, the active matter can be continuously and slowly released, and the release rate has environmental ion strength responsiveness.

The invention discloses a full bio-based hydrogel ball as well as a preparation method and application thereof, and belongs to the technical field of hydrogel. According to the full-bio-based hydrogel ball provided by the invention, cellulose nanofibers (CNF), lignin nanobottles (LNBs) and sodium alginate (SA) are integrated, a three-dimensional network structure with high-density negative charge functional sites is constructed, and selective adsorption separation of target protein is realized by utilizing electrostatic interaction. CNF, SA and carboxyl groups and phenolic hydroxyl groups on the surfaces of LNBs form a high-density negative charge network, and the equilibrium adsorption capacity of protein reaches 1200 mg / g under the conditions of pH 6 and zero salt ion strength.

Provided are a method for concentrating a water-soluble protein and a method for recovering a water-soluble protein using the same, whereby it is possible to increase the concentration ratio of the water-soluble protein while maintaining the recovery rate of the water-soluble protein. The present invention relates to a method for concentrating a water-soluble protein, which is a method for separating and concentrating a water-soluble protein that is soluble in a salt solution having an ionic strength of 0.1 mol / L or less, the method comprising: supplying a supply solution containing the water-soluble protein to an NF membrane; a concentration step for separating the supply liquid into a permeate and a concentrated liquid such that the ion strength (mol / L) of the concentrated liquid is 1.0-2.0 times the ion strength (mol / L) of the supply liquid; also disclosed is a method for recovering a water-soluble protein, which comprises a desalination step for separating a salt from the concentrated solution obtained by an ion exchange resin method and / or an electrodialysis method after the concentration method has been performed.

An aqueous composition having a pH in the range of 4.0–8.5, comprising: an antibody construct containing an Fc domain; optionally, one or more buffers having at least one ionizable group and a pK value in the range of 3.0 to 9.5. a And its PK a Within 2 pH units of the pH of the composition; optionally, one or more neutral amino acids; and an uncharged tension modifier; wherein the total concentration of the buffer in the composition is 0-5 mM; and wherein the total ionic strength of the composition is less than 20 mM, excluding the contribution of engineered protein constructs.

The invention belongs to the technical field of food industry, and particularly relates to seville orange flower Pickering emulsion as well as a preparation method and application thereof. The seville orange flower Pickering emulsion which has good stability under the conditions of extreme pH, high ionic strength, temperature fluctuation and the like is prepared by taking nano esterified starch as solid colloidal particles and taking a mixed oil phase of seville orange flower essential oil and carrier oil as a dispersion phase. Performance test results show that when the emulsion is heated at 80 DEG C for 1 h, the particle size of the emulsion is basically kept unchanged, the polydispersity index (PDI) is slightly reduced or kept stable, and the zeta potential is slightly reduced, which indicates that the emulsion has good thermal stability; under the strongly alkaline condition that the pH is 11, the particle size and zeta potential of the emulsion are slightly changed, and only the polydispersity index is slightly increased; in a high-concentration NaCl environment, various parameters of the emulsion are not obviously changed, and the emulsion shows relatively high ion interference resistance.

The application belongs to the technical field of medicine extraction and medicine detection, and discloses a detection method of related substances in palonosetron-containing fat emulsion injection. Methanol is used as a main demulsifier, and a sodium dihydrogen phosphate buffer salt solution with a suitable ionic strength is used for assistance, so that full demulsification is realized under the premise of not introducing a third organic phase; a water bath evaporation and redissolution method is used to enrich target components in the solution after demulsification, so that good chromatographic behavior and complete recovery of the target components are ensured, and the detection sensitivity is effectively improved. The palonosetron and related impurities have good separation degree, the method is simple to operate, accurate to measure, and strong in specificity, and is suitable for the determination of palonosetron related substances in rolapitant palonosetron fat emulsion.

The present invention discloses a hyaluronic acid indicator composition and its use in the rapid detection of hyaluronic acid substances. The composition contains zerovalent iodine, has an ionic strength greater than 2000µs / cm, and has a pH of 2.0 to 9.0. The hyaluronic acid indicator composition of the present invention can be used for rapid qualitative detection of hyaluronic acid substances. The detection method is simple, low-cost, and requires no pretreatment of the product. A visible color change can be produced within a specified time, resulting in a short detection time, thereby enabling rapid detection of hyaluronic acid substances.