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23 results about "Ionic strength" patented technology

The concept of ionic strength was first introduced by Lewis and Randall in 1921 while describing the activity coefficients of strong electrolytes. The ionic strength of a solution is a measure of the concentration of ions in that solution. Ionic compounds, when dissolved in water, dissociate into ions. The total electrolyte concentration in solution will affect important properties such as the dissociation constant or the solubility of different salts. One of the main characteristics of a solution with dissolved ions is the ionic strength. Ionic strength can be molar (mol/L) or molal (mol/kg water) and to avoid confusion the units should be stated explicitly.

A method for reducing the stability of amorphous calcium phosphate

This invention discloses a method for reducing the stability of amorphous calcium phosphate. The method involves adding an additive solution to an ACP solution; the additive is a calcium- and phosphorus-free inorganic salt that does not react with calcium ions and orthophosphate ions to form a precipitation reaction. This invention, by adding an inorganic salt after the formation of amorphous calcium phosphate, primarily increases the ionic strength of the solution, reduces calcium and phosphorus activity, promotes the dissolution of amorphous calcium phosphate, thereby altering its structure, significantly reducing its stability, and accelerating the formation of hydroxyapatite. Furthermore, this method uses low-cost raw materials, contributing to cost reduction.
Owner:SOUTH CHINA UNIV OF TECH

Method for simultaneously testing content of iodide ions and bromide ions in nylon 66 polymer

The invention belongs to the technical field of nylon 66 polymer performance testing, and particularly relates to a method for simultaneously testing the content of iodide ions and bromide ions in a nylon 66 polymer, which comprises the following steps of: extracting the iodide ions and the bromide ions in the polymer by using weak acid salt (sub-carbonate or bicarbonate) instead of potassium nitrate as an ionic strength regulator; the acid environment in the extracted solution is adjusted with formic acid, silver nitrate is adopted as a titrant, iodide ions and bromide ions in the extract liquor are detected at the same time through potentiometric titration, and the problem that the iodide ions and the bromide ions cannot be detected at the same time is solved.
Owner:SHEN MA INDUSTRY CO LTD

Novel compositions comprising antibodies

An aqueous solution composition having a pH in the range of 4.0 to 8.5, comprising: an antibody construct comprising an Fc domain; optionally, one or more buffering agents which are a substance having at least one ionizable group, have a pKa in the range of 3.0 to 9.5, and have a pKa within 2 pH units of the pH of the composition; optionally, one or more neutral amino acids; and an uncharged tension regulator; wherein the total concentration of the buffer in the composition is 0-5 mM; and wherein the composition has a total ionic strength of less than 20 mM, excluding the contribution of engineered protein constructs.
Owner:AIR OK LTD

Nano-silver particle size standard substance and preparation method thereof

The invention belongs to the technical field of stoichiometry, and discloses a nano-silver particle size standard substance and a preparation method thereof, the standard substance is composed of nano-silver particles, a stabilizer, a dispersion medium and a buffer system, the specific composition is as follows: the average particle size of the nano-silver particles is 40-60 nm, the particle size distribution standard deviation is less than 5 nm, and the nano-silver particles are spherical or torispherical; the stabilizer is selected from polyvinylpyrrolidone (PVP) or polyethylene glycol (PEG), the molecular weight of the stabilizer is 10 * 10 < 3 >-40 * 10 < 3 >, and the addition amount of the stabilizer is 5-10 times of the mass of silver; the dispersion medium is formed by mixing deionized water and absolute ethyl alcohol according to the volume ratio of (9: 1)-(8: 2), and the conductivity of the dispersion medium is lower than 1 mu S / cm; the buffer system adopts a boric acid-borax system, the pH is controlled between 8.0 and 9.0, and the buffer concentration is 5mmol / L to 10mmol / L, so that the ionic strength of the dispersion system and the surface potential stability of particles are maintained. And high controllability of the particle size and inter-batch repeatability are realized.
Owner:SILKWORM COCOON RES GROUP CHINESE INST OF TEST TECH

Zinc phthalocyanine polyhalide, coloring composition, color filter, and method for producing zinc phthalocyanine polyhalide.

This invention provides zinc phthalocyanine polyhalogenate, which contributes to improving the brightness of color filters. [Solution] A zinc phthalocyanine polyhalide comprising a compound represented by the following general formula (i), wherein, in the mass spectrum obtained by matrix-assisted laser desorption / ionization time-of-flight mass spectrometry, when the maximum ionic intensity in the range of m / z 1820 to 1860 is denoted as I1 and the maximum ionic intensity in the range of m / z 1740 to less than 1780 is denoted as I2, the ratio I2 / I1 is 0.50 or less. TIFF2026086779000008.tif68149
Owner:DIC CORP

Novel composition comprising antibodies

PendingUS20260077016A1Antibody mimetics/scaffoldsPeptide/protein ingredientsNeutral Amino AcidsIonic strength
An aqueous solution composition of pH in the range 4.0-8.5 comprising:an antibody construct comprising an Fc domain;optionally one or more buffers being substances having at least one ionisable group with a pKa in the range 3.0 to 9.5 and which pKa is within 2 pH units of the pH of the composition;optionally one or more neutral amino acids; andan uncharged tonicity modifier;wherein the buffers are present in the composition at a total concentration of 0-5 mM; andwherein the total ionic strength of the composition excluding the contribution of the engineered protein construct is less than 20 mM.
Owner:ARECOR LTD

Coastal wetland plant maintenance system and method

The invention relates to the technical field of irrigation, and discloses a coastal wetland plant maintenance system and method.The method comprises the steps that firstly, concentration spatial distribution of thiosulfate and tetrathiosulfate in a root domain is obtained, the spatial position and the peak shape curvature of a concentration ratio peak are determined based on the concentration spatial distribution, and meanwhile the outer edge spatial position of a root surface iron plaque is determined; calculating position deviation and curvature deviation between the two; further measuring the root domain volume and the ion strength and sulfate radical concentration of pore water; then, a small amount of fresh water and brackish water are injected into the root domain, the spatial position of a concentration ratio peak and the change rate of curvature are observed, and the hydrochemistry and root domain reaction relation is established; according to the deviation and the change rate, the required ion strength and the sulfate radical concentration adjustment amount are solved, the volume of fresh water and the volume of brackish water required by single-time maintenance are accurately converted according to the root domain volume and the ion characteristics of different water sources, and therefore scientific regulation and control over the coastal wetland plant root domain environment are achieved.
Owner:FUDAN UNIVERSITY

Sample pretreatment method for detecting total sulfur dioxide content in spice matrix and determination method

The invention discloses a sample pretreatment method and a determination method for detecting the total sulfur dioxide content in a spice matrix, and the method comprises the following steps: adding a surfactant and an antioxidant into an aqueous dispersion of a spice matrix sample, and then carrying out stepped temperature control heat treatment under an alkaline condition; and adding inorganic salt into the obtained liquid phase to enhance the ionic strength, extracting and purifying to finish the pretreatment process for subsequent detection of the total sulfur dioxide content. According to the method, the pretreatment process is effectively improved, the total sulfur dioxide in the matrix is effectively and accurately enriched through catalytic liberation and in-situ protection of the combined sulfur dioxide in the spice matrix and by combining the dual means of salting-out anchoring and physical purification, the problem of multiple interferences existing in an existing pretreatment means is systematically solved, and the method is suitable for large-scale popularization and application. And finally, rapid, accurate and reliable determination of the total sulfur dioxide in the spice matrix is realized.
Owner:CHINA GREEN FOOD DEV CENT +1

Method of purification

PCT designated stageWO2026115259A1Cation exchanger materialsOrganic anion exchangersIonic strengthPurification methods
The invention provides a chromatographic method for separating pre-contraction state PVC Nanosyringes from post-contraction state PVC Nanosyringes, the method comprising: (a) providing a sample containing both pre- and post-contraction state PVC Nanosyringes; (b) loading the sample on a monolith anion exchange column having (preferably quaternary amine) binding moieties, under conditions (e.g. pH 7-8, temperature 19-25°C) wherein pre- and post-contraction state PVC Nanosyringes become bound to the column with differing affinities; (c) applying a gradient of ionic strength to the column that provides for differential elution of the pre- and post-contraction state PVC Nanosyringes, wherein the gradient is generated by incrementally (e.g. linearly) increasing the salt concentration of a mobile phase elution buffer that is applied to the column; and (d) eluting the pre- and post-contraction state PVC Nanosyringes into separate elution fractions under the gradient based on their differing affinities to the anion exchange column, and collecting fractions having the pre-contraction state PVC Nanosyringes separated from the post-contraction state PVC Nanosyringes.
Owner:NANOSYRINX LTD

Controllable slow-release peracetic acid disinfectant and preparation process thereof

PendingCN121465018ABiocideDisinfectantsMatrix solutionBoronic acid
The invention relates to the technical field of disinfectants, and discloses a controllable slow-release peracetic acid disinfectant and a preparation process thereof, and the disinfectant is prepared from peracetic acid equilibrium liquid, boric acid, polyol, polyaspartic acid solution and other raw materials. The structure is characterized in that peroxyacetic acid and boric acid form a reversible complex, and the reversible complex is dispersed in a continuous phase matrix with polyol as a main body as a dispersion phase. The preparation process adopts a step-by-step heterogeneous compounding method, and comprises the following steps: firstly, independently preparing an activation complexing solution containing a peracetic acid-boric acid complex; then independently preparing a matrix solution containing polyhydric alcohol and polyaspartic acid; and finally, dispersing the activated complexing solution into a matrix solution under the shearing action, curing and adjusting the pH value to obtain a final product. The process avoids the loss of active matters in the preparation process. The disinfectant has the advantages that the storage stability is high, the active matter can be continuously and slowly released, and the release rate has environmental ion strength responsiveness.
Owner:SHANDONG ZHUOJIAN MEDICAL TECH CO LTD

New compositions comprising antibodies

An aqueous composition having a pH in the range of 4.0–8.5, comprising: an antibody construct containing an Fc domain; optionally, one or more buffers having at least one ionizable group and a pK value in the range of 3.0 to 9.5. a And its PK a Within 2 pH units of the pH of the composition; optionally, one or more neutral amino acids; and an uncharged tension modifier; wherein the total concentration of the buffer in the composition is 0-5 mM; and wherein the total ionic strength of the composition is less than 20 mM, excluding the contribution of engineered protein constructs.
Owner:AIR OK LTD

Method for extracting gastrodia elata phenolic compound by ionic strength response type eutectic solvent mediated aqueous two-phase system

The invention discloses a method for extracting gastrodia elata phenolic compounds by an ionic strength response type deep-eutectic solvent mediated aqueous two-phase system, which comprises the following steps: mixing gastrodia elata powder with a deep-eutectic solvent, and carrying out ultrasonic extraction to obtain a DES extracting solution containing the gastrodia elata phenolic compounds; mixing and stirring the DES extracting solution and a K3PO4 solution, and centrifuging to obtain a DES-rich top phase and a salt-rich bottom phase; mixing and stirring the DES-rich top phase and a KH2PO4 solution, and centrifuging to obtain supernatant and precipitate rich in gastrodia elata phenolic compounds; and adding water into the obtained precipitate to realize regeneration of the eutectic solvent, and circularly applying the eutectic solvent to ultrasonic extraction. According to the method, efficient enrichment, separation and purification of gastrodia elata phenolic substances and recovery and reuse of DES can be synchronously achieved through the ionic strength response type eutectic solvent mediated aqueous two-phase system, the process is simple, operation is mild, and the method is suitable for industrial application.
Owner:ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE

Low-alpha radiation silica and its preparation method

This application relates to a low-alpha-ray silica and its preparation method. The method involves adding a high-purity sodium sulfate solution to water glass, followed by the sequential addition of dilute sulfuric acid solutions of varying concentrations for aging. The resulting precipitate is then calcined to obtain low-alpha-ray silica with Th ≤ 5 ppb and U ≤ 5 ppb. The sodium sulfate solution optimizes the precipitation process in two ways: first, it increases the ionic strength of the solution, compresses the colloidal double layer, and disrupts the metastable state of the system, thus promoting the aggregation and crystallization of the target precipitate; second, sulfate ions preferentially complex or inhibit the precipitation tendency of impurity cations based on the common ion effect; furthermore, the dilute sulfuric acid solution promotes the reaction and rapid precipitation of silicate ions with hydrogen ions, causing the Th and U ions encapsulated in the precipitate to precipitate out, thereby reducing the impurity content in the solution. This low-alpha-ray silica, due to its extremely low Th and U content and good thermal conductivity, can be widely used in high-performance and special-purpose chip packaging fields.
Owner:CHALCO SHANDONG CO LTD

Separation of nucleic acid component compounds on zwitterionic stationary phases

The present disclosure pertains to methods of separating nucleic acid component compounds from one another. In some embodiments, the methods comprise: (a) loading a sample fluid comprising a plurality of nucleic acid component compounds onto a chromatographic column comprising a zwitterionic stationary phase contained inside the column; (b) flowing a mobile phase through the chromatographic column over a time period thereby forming an eluent in which at least some of the plurality of the nucleic acid component compounds are separated from each other, the mobile phase comprising a polar aprotic solvent, a protic solvent, and a volatile buffer salt, wherein flowing the mobile phase comprises varying a ratio of the protic solvent to the polar aprotic solvent over at least a portion of the time period and varying an ionic strength of the volatile buffer salt over at least a portion of the time period.
Owner:WATERS TECHNOLOGY CORP

High-stability dust suppression foam based on ion in-situ shielding effect and construction process thereof

The invention relates to the technical field of mine safety and dust prevention and control, and discloses high-stability dust suppression foam based on the ion in-situ shielding effect and a construction technology thereof.The foam is prepared from a coalescing agent, a surfactant, an ion shielding agent and a hard water solvent. The preparation method comprises the following steps: preparing a film forming aid solution, compounding a basic foaming solution, adding an ion shielding agent, carrying out continuous suspension treatment and interface reconstruction, and finally carrying out physical foaming to prepare the gas-liquid-solid interface film, wherein the basic foaming solution, the film forming aid solution and the surfactant are cooperated to construct the stable gas-liquid-solid interface film, and the preparation method comprises the following steps: preparing the film forming aid solution, compounding the basic foaming solution, adding the ion shielding agent, carrying out continuous suspension treatment and interface reconstruction, and finally carrying out physical foaming. The problems of poor foam stability and low dust suppression efficiency caused by mine high-hardness water quality are effectively solved, and the obtained foam is low in surface tension, long in drainage half-life period, high in coal dust wetting speed and suitable for a mine high-salinity water quality environment.
Owner:ANHUI UNIV OF SCI & TECH

Method for testing and evaluating carbonate dissolved weathering carbon sink

The invention discloses a method for testing and evaluating carbonate dissolved and weathered carbon sinks, which comprises the following steps of: acquiring and preprocessing multi-source data, constructing a carbonate rock exposure mask, establishing a soil carbon dioxide partial pressure multivariable estimation model, and calibrating an observation data area of water-containing chemical and equilibrium information to obtain gridded soil carbon dioxide partial pressure distribution; the dynamic ion strength and the corrected ion activity coefficient are calculated in combination with hydrological process and hydrochemical data, the maximum potential carbonate dissolution rate is solved and converted into the carbonate dissolution and weathering carbon sink amount, a comprehensive carbon sink index representing the carbon sink capacity and stability is constructed, and a carbon sink enhanced hot spot area and a sensitive response zone are identified. According to the method, the contribution of various external forces such as quantitative separation of greenhouse gases, natural force, aerosol, land utilization and the like to carbonate dissolved-weathered carbon convergence is provided, and a new tool is provided for carbon cycle response evaluation in future climate scenarios.
Owner:INST OF GEOGRAPHICAL SCI & NATURAL RESOURCE RES CAS

Intercalation agent for preparing graphene as well as preparation method and application of intercalation agent

PendingCN122010105AGrapheneIonic strengthGraphene
The invention belongs to the technical field of graphene preparation, and particularly relates to an intercalator for graphene preparation and a preparation method and application thereof. The preparation method of the intercalator for graphene preparation comprises the following steps: (1) providing a sodium cholate aqueous solution as a basic solution; (2) adding a microenvironment regulating agent into the basic solution, and regulating and stabilizing the pH value and / or ionic strength I of the system to a preset target value; (3) dropwise adding an aqueous solution containing calcium ions into the solution obtained in the step (2) under the conditions of continuous stirring and temperature control, and controlling the final molar concentration ratio R of the calcium ions to the sodium cholate to a preset value; and (4) curing the mixed solution obtained in the step (3) at a set temperature to obtain the intercalator for graphene preparation. The intercalator system provided by the invention has definite environmental response and self-adaptive characteristics, and is beneficial to obtaining graphene with narrow layer number distribution and high quality when being used for preparing graphene.
Owner:QINGDAO UNIV OF TECH

A method for determining the content of a mixture of different forms of sulfate

The application aims to provide a content determination method of a mixture containing different morphological sulfate salts. The method comprises the following steps: obtaining a to-be-tested solution which may contain sulfite, sulfate, thiosulfate and persulfate; determining the to-be-tested solution by using an electrospray high-resolution mass spectrometry to obtain characteristic ion intensity in the to-be-tested solution; and calculating the concentration of various morphological sulfate salts in the to-be-tested solution according to the characteristic ion intensity. The method is simple in operation, short in analysis time, convenient and fast. The method can qualitatively and quantitatively analyze different morphological sulfate salts without chromatographic separation.
Owner:CHONGQING UNIV +1

Preparation method and application of carrageenan-based cosmetic soft capsules

The present application relates to carrageenan technical field, specifically to a kind of preparation method and application of carrageenan-based cosmetic soft capsule, comprising: preparation active oil phase solution and crosslinking solution, using active oil phase solution and crosslinking solution to pretreat coordination sol, obtain functional crosslinking material.The shell of the present application has mechanical strength, environmental responsiveness and long-term structural stability, and the capsule shell presents the gradient structure of outer compactness and inner porosity, which can effectively lock the oil core and prevent leakage, and the inner layer acts as a buffer layer to prevent the overall brittle fracture of the capsule shell when stressed, ensuring the smooth release of active substances;At the same time, the soft capsule has skin environment triggered release ability, and the zinc-polyphenol dynamic coordination bond in the inner layer of the capsule shell is sensitive to the weak acidic pH environment and the ion strength of sweat, and after contacting the skin, the coordination network is loose, the capsule shell is swollen and softened, and the controlled release of the oil core can be realized by combining with the external force of rubbing and rubbing, which significantly improves the bioavailability and use experience of active substances.
Owner:YANTAITAISHENBIOTECHNOLOGY CO LTD

Self-assembling peptide compositions

PendingUS20260116919A1Nervous disorderSurgical adhesivesIonic strengthElevated ph
The present disclosure provides peptide compositions (e.g., of self-assembling peptides) with particular attributes (e.g., peptide identity, peptide concentration, pH, ionic strength (including salt identity and / or concentration), etc. that show particularly useful material properties. The present disclosure also provides technologies for selecting and / or formulating particular peptide compositions useful in specific contexts. In some embodiments, provided peptide compositions have an elevated pH within the range of about 2.5 to about 3.5 and / or an ionic strength that is above that of a corresponding composition of the same peptide, at the same concentration, in water, but is below a critical salt point for the peptide (e.g., so that the composition is not cloudy).
Owner:3D-MATRIX LTD

Novel compositions comprising antibodies

An aqueous solution composition having a pH in the range of 4.0 to 8.5, comprising: an antibody construct comprising an Fc domain; optionally, one or more buffering agents which are a substance having at least one ionizable group, have a pKa in the range of 3.0 to 9.5, and have a pKa within 2 pH units of the pH of the composition; optionally, one or more neutral amino acids; and an uncharged tension regulator; wherein the total concentration of the buffer in the composition is 0-5 mM; and wherein the composition has a total ionic strength of less than 20 mM, excluding the contribution of engineered protein constructs.
Owner:AIR OK LTD

Core-shell structure modified double-layer hydrogel self-healing material and preparation method thereof

PendingCN122167064AIonic strengthCalcium alginate
This invention discloses a core-shell structure-modified bilayer hydrogel self-healing material and its preparation method. The material comprises a nano-microscale wollastonite-modified hydrogel core layer and a calcium alginate shell layer formed by slow-release in-situ crosslinking with calcium ions. The hydrogel core layer is prepared by a suspension method. The shell layer is formed by adsorbing calcium ions in a calcium chloride solution through the hydrogel core layer and then slowly releasing and crosslinking with a sodium alginate solution. The sodium alginate chains are linked with the calcium... 2+ It forms an "egg box" structure; through the synergistic effect of the core and shell structure, functional zoning is achieved. The nano- and micro-sized wollastonite significantly improves the mechanical stability of the material. The shell layer can not only shield the cement-based high alkalinity and high ionic strength environment to protect the activity of the core layer, but also respond and trigger when cracks are generated or water invades. Combined with the synergistic healing effect of hydrogel swelling and sealing and wollastonite hydrolysis and mineralization, it can solve the problems of poor mechanical properties, insufficient hydrolysis resistance, easy premature release of healing agent, and difficulty in balancing stability and response sensitivity of traditional superabsorbent resins.
Owner:CHINA RAILWAY MAJOR BRIDGE ENG GRP CO LTD +1