266 results about "Anion exchanger" patented technology

PCT No. PCT/SE97/00237 Sec. 371 Date Dec. 29, 1998 Sec. 102(e) Date Dec. 29, 1998 PCT Filed Feb. 14, 1997 PCT Pub. No. WO97/29825 PCT Pub. Date Aug. 21, 1997Process for separating off a peptide or a nucleic acid by an anion exchanger (I) characterized in that a) the anion exchanger (I) exhibits ligands, which (i) contain a primary, secondary or tertiary amino group and (ii) are covalently bound to an organic polymer (matrix), b) there on a carbon atom at a distance of 2 or 3 atoms away from an amino nitrogen in the ligands is a hydroxyl group or a primary, secondary or tertiary amino group, and c) the maximum elution ionic strength in the pH range 2-14 for at least one of the proteins transferrin, ovalbumin 1, ovalbumin 2, beta -lactoglobulin 1 and beta -lactoglobulin 2 on the anion exchanger is higher than the elution ionic strength required for a quaternary comparative ion exchanger.

The present invention provides a lithium-air secondary battery that is capable of effectively preventing deterioration of an alkaline electrolytic solution, air electrode, and negative electrode and has a long life and high long-term reliability. The lithium-air secondary battery comprises an air electrode 12 functioning as a positive electrode, an anion exchanger 14 provided in close contact with one side of the air electrode and composed of a hydroxide-ion conductive inorganic solid electrolyte, a separator 16 provided away from the anion exchanger and composed of a lithium-ion conductive inorganic solid electrolyte, a negative electrode 18 provided so as to be capable of supplying and receiving lithium ions to and from the separator and comprising lithium, and an alkaline electrolytic solution 20 filled between the anion exchanger and the separator.

Media and devices, such as anion exchangers including such media, wherein the media is a membrane having a surface coated with a polymer such as a polyallylamine. The resulting membrane offers stronger binding of protein impurities and superior removal of host cell proteins from biological samples than conventional ligands based on quaternary ammonium salts, including trimethylammonium ligands. Also described is a chromatography scheme and method for purifying monoclonal antibodies, wherein the anion exchange sorber is placed downstream of an affinity column (such as Protein A or Protein G affinity column) and optionally one or more polishing devices such as cationic exchange columns. Little or no dilution of the cation exchanger pool (or affinity column exchange pool where no cation exchanger is used) is necessary to lower the conductivity of the sample. The sorber functions well to strongly bind host cell proteins and other impurities in biological samples even at high conductivities and pH.

The present invention relates to a process for preparing novel, monodisperse anion exchangers by

• (a) reacting monomer droplets made from monovinylaromatic compounds and polyvinylaromatic compounds, and optional porogens and/or initiators,
• (b) amidomethylating the resultant monodisperse, crosslinked bead polymers with phthalimide derivatives,
• (c) converting the amidomethylated bead polymers to aminomethylated bead polymers, and
• (d) alkylating the aminomethylated bead polymers.

The invention discloses a process for treating nitrogen-containing wastewater by ion exchange and reclaiming ammonium nitrate, and belongs to the technical field of environmental protection and wastewater treatment. The process is characterized in that: a strong acid cation exchanger and a weak alkali anion exchanger are connected in series to realize denitrification of the nitrogen-containing wastewater of a nitrogen fertilizer plant; the process is used for treating the high-concentration ammonia nitrogen and median-concentration nitrate nitrogen containing wastewater of the nitrogen fertilizer plant; strong acid cation exchange resin and weak alkali anion exchange resin are regenerated by adopting nitric acid and aqueous ammonia respectively; and the regenerated waste liquid ammonium nitrate is evaporated and concentrated to reclaim the ammonium nitrate. Compared with the traditional wastewater denitrification method, the process can remove ammonia nitrogen and nitrate nitrogen from the wastewater at the same time, reclaim the ammonium nitrate and recycle production water, does not produce secondary pollution, reclaims products from the pollutants, has obvious environmental benefit and economic benefit, and is a new path for treating the high-concentration ammonia nitrogen and median-concentration nitrate nitrogen containing wastewater of the nitrogen fertilizer plant.

A method of purifying biomolecules with an anion exchanger containing a membrane having a surface having a polymer such as a primary or secondary amine ligand formed thereon, such as polyallylamine. The feedstock is introduced to the exchanger in the presence of one or more ionic-modifiers by themselves or in combination with monovalent salt. The ionic modifier alters the binding ability of the primary amines such that they retain a significant binding capacity for highly charged species such as DNA but lose part or almost all of their binding capacity for less charged species such as viruses or proteins at pH above the pI of the virus or protein.

The invention provides an improved method for the purification of nucleic acid molecules, which method comprises generating a cellular lysate containing the nucleic acid; contacting the lysate with an anion exchanger bound to a solid support matrix under conditions such that the anion exchanger binds the nucleic acid; followed by eluting the nucleic acid from the anion exchanger with an aqueous mobile phase comprising an elution solution; and desalting the eluted nucleic acid such that it is suitable for downstream applications. The improvement of the method includes adding in the elution solution a composition such that the pH of the aqueous mobile phase is between about pH 9 and about pH 13, wherein the presence of the composition in the elution solution provides an increase in nucleic acid recovery, as compared with the recovery in the absence of the composition.

Embodiments of the present invention are directed to a substrate for performing ionization desorption on porous silicon, methods for performing such ionization desorption and methods of making substrates. One embodiment directed to a substrate for performing ionization desorption on silicon comprises a substrate having a surface having a formula of:

As used above, X is H or Y, where at least at least twenty five mole percent of X is Y and Y is hydroxyl, or —O—R₁ or O—SiR₁,R₂,R₃ wherein R₁,R₂, and R₃ are selected from the group consisting C₁ to C₆ straight, cyclic, or branched alkyl, aryl, or alkoxy group, a hydroxyl group, or a siloxane group, and R⁶ may be a C₁ to C₃₆ straight, cyclic, or branched alkyl (e.g., C_18, cyanopropyl), aryl, or alkoxy group, where the groups of R⁶ are unsubstituted or substituted with one or more moieties such as halogen, cyano, amino, diol, nitro, ether, carbonyl, epoxide, sulfonyl, cation exchanger, anion exchanger, carbamate, amide, urea, peptide, protein, carbohydrate, and nucleic acid functionalities. The letter “n” represents an integer from 1 to infinity and any vacant valences are silicon atoms, hydrogen or impurities.

Process for separating proteins fibrinogen, Factor XIII and biological glue from a solubilized plasma fraction and for preparing lyophilised concentrates of said proteins

Summary

The invention is related to a process for separating proteins fibrinogen, Factor XIII and biological glue from a solubilized plasma fraction and for preparing freeze-dried concentrates of said proteins comprising the steps of:

• • chromatographic purification comprising the steps of loading an anion exchanger of weak base type with the said solubilized fraction, previously equilibrated with a buffer of a predetermined ionic strength of an alkaline pH, which allows to retain the biological glue, elution of the biological glue by increasing the ionic strength of the said buffer, and
  • separation of FXIII from fibrinogen by addition to at least one part of the biological glue eluate of at least one chemical agent precipitating the FXIII, and recovery of the resulting purified fibrinogen containing supernatant solution, and
  • diafiltration of the fibrinogen, biological glue and resolubilized FXIII solutions, followed by a freeze-drying of said solutions. It is also related to freeze-dried concentrates of the said proteins capable to be obtained by carrying out the process.

The invention relates to a method for producing a purified solution containing L-cysteine from a fermentation broth containing L-cysteine. In said method, the fermentation broth containing L-cysteine, at a pH value from pH 6 to 9, is brought in contact with a basic anion exchanger, wherein the L-cysteine bonds to the anion exchanger. The anion exchanger is then rinsed with a first washing solution, and the bonded L-cysteine is removed from the anion exchanger by means of an acid and transferred into an eluate. Said eluate, having a pH≦4, is brought in contact with an acidic cation exchanger, wherein the L-cysteine bonds to the cation exchanger. The cation exchanger is rinsed with a second washing solution, and the bonded L-cysteine is removed from the cation exchanger by means of a strong acid.

The invention discloses a system and method for fine treatment of condensation water. The system comprises a pipeline inlet, a cation exchanger, a cation-anion exchanger, a filter, a booster pump and a pipeline outlet which are connected in series in sequence through connecting pipelines; a valve 1 and a valve 3 are arranged between the pipeline inlet and the cation exchanger; a valve 4 and a valve 6 are arranged between the cation-anion exchanger and the filter; a valve 7 is arranged between the filter and the booster pump; a valve 8 is arranged on the connecting pipeline between the booster pump and the pipeline outlet; and the pipeline inlet is communicated with the pipeline outlet through a valveless bypass. According to the system and the method, metal corrosion products and suspended solids can be effectively removed, ion exchange resin can be protected, the condition for putting the ion exchangers into operation can be met as soon as possible, the time for flushing the pipelines is shortened, and the waste of water resources is reduced; and tiny resin particles can be effectively captured after the ion exchangers are normally operated, so that the operation safety of two thermal devices is kept.

The invention provides an improved method for the purification of nucleic acid molecules, which method comprises generating a cellular lysate containing the nucleic acid; contacting the lysate with an anion exchanger bound to a solid support matrix under conditions such that the anion exchanger binds the nucleic acid; followed by eluting the nucleic acid from the anion exchanger with an aqueous mobile phase comprising an elution solution; and desalting the eluted nucleic acid such that it is suitable for downstream applications. The improvement of the method includes providing the anion exchanger in a packed column, wherein the column is packed using a salt solution containing an antimicrobial agent. In addition, the salt solution has a salt concentration similar to that of the lysate, such that the column does not need equilibration prior to sample loading.

A process to substantially remove fluorinated anionic surfactants from fluoropolymer dispersions comprising the following steps: a) addition to the fluoropolymer dispersion of one or more non fluorinated surfactants; b) contact of the dispersion with an anionic exchanger; c) separation of the dispersion from the anionic exchanger and recovery of the dispersion substantially fluorinated anionic surfactant free.

A performance-lowered ion exchanger hard to recover in performance by the conventional regeneration (ion exchange resin, ion exchange membrane, or the like) is endowed with the same electric charge as the electric charge of the ion exchanger. A performance-lowered ion exchanger hard to recover in performance by the conventional regeneration owing to adsorption thereon of a charged substance is endowed with an electric charge opposite to that of the charged substance. According to the foregoing operations, the ion exchangers are recovered in performance. At least one compound selected from among organic amine compounds and organic ammonium compounds, which are capable of being endowed with an electric charge through dissociation thereof in solution, is preferably used as a rejuvenation agent for an anion exchanger.

The invention discloses an anion-exchange agent prepared by using fermented straws and a preparation method thereof. The anion-exchange agent is brown or red brown solid powder in appearance, the Zeta electric potential is 10 to 40mv, the nitrogen content is 2.0 to 6.0 percent and the pH value of aqueous solution of the anion-exchange agent is 4 to 6; and the anion-exchange agent is prepared by using fermented straws, epoxy chloropropane and triethylamine or dimethylamine as raw materials and using amide as a crosslinker. The preparation method prepares the anion-exchange agent by using the fermented straws, the epoxy chloropropane and the triethylamine or dimethylamine as raw materials and using the amide as the crosslinker, has the characteristics of simple production process, high production efficiency, economy and the like and is suitable to be used for large-scale production. The prepared anion-exchange agent has the advantages of secondary pollution prevention, high product stability, desirable absorption effect, wide application range, low cost, large-scale production and use and the like. The anion-exchange agent can be widely used in waste water treatment with excellent treatment effect.

The invention discloses a system and a method for manufacturing demineralized water. The system comprises an industrial water inlet, a pretreatment device, a cation exchanger, a carbon remover, an anion exchanger, a primary mixed bed, a demineralized water tank and a demineralized water outlet which are sequentially connected with one another by pipelines; a primary demineralized water tank, a reverse osmosis water feeding pump, a cartridge filter, a high-pressure pump, a reverse osmosis device, a reverse osmosis water manufacturing tank and a fresh water pump are sequentially arranged on the connecting pipeline between the anion exchanger and the primary mixed bed; a polishing mixed bed is arranged on the connecting pipeline between the primary mixed bed and the demineralized water outlet. The system and the method have the advantages that suspension, colloid, organic matters and cation and anion impurities in water can be removed, and total organic carbon in the water further can be effectively removed, so that power generation sets can safely and stably run for a long time.

The object is to provide an amorphous inorganic anion exchanger having excellent anion exchangeability and suppressed corrosivity toward metals and to provide a production process that can produce an amorphous bismuth compound having excellent anion exchangeability and suppressed corrosivity toward metals.

The amorphous inorganic anion exchanger of the present invention is represented by Formula (1) and has an average primary particle size observed with an electron microscope of at least 1 nm but no greater than 500 nm and an NO₃ content of no greater than 1 wt % of the whole.

The process for producing an amorphous bismuth compound of the present invention includes a precipitate formation step of forming a precipitate by subjecting an acidic aqueous solution containing trivalent Bi ions to a temperature in the range of higher than 0° C. but less than 20° C. and a pH of at least 12, the amorphous bismuth compound thus obtained being represented by Formula (1) and having an NO₃ content of no greater than 1 wt %.

BiO(OH)  (1)

The invention discloses a method for preparation of ultrapure water with bipolar-film electrodeionzation and the device. The device contains an anode chamber with anode, a cathode chamber with catelectrode, and several three-chamber units sequentially from anode to catelectrode comprising of a condensation chamber filled with anion exchanger, the second desalination chamber and the first desalination chamber with cation exchanger; between the chambers are sequentially equipped with cation exchange film, bipolar film, and anion exchange film. The method contains: energizing the catelectrode and anode with direct current, the electrode water flowing sequentially from the anode chamber to the cathode chamber; raw water flowing sequentially through the first desalination chamber and the second desalination chamber, electrodeionzation to produce ultrapure water; and the liquid inlet to condensation chamber being water solution of low conductivity, the solution between condensation chamber to second desalination chamber reflowing. The merit of the invention is characterized in that, compared with the prior art that ultrapure water is prepared by electrodeionzation in mixed bed, weakly-acidic anion impurity silicon, boron, CO2 and so on in water can be removed effectively, and the area of ion exchange film can be distinctively decreased and thus the investment is saved.