287results about "Ether separation/purification" patented technology

The invention relates to a phenylpropanoid compound as well as a preparation method and application thereof, in particular to a phenylpropanoid compound extracted from pleione bulbus pseudobulb as well as a preparation method and application thereof, and belongs to the technical field of medicines. The invention provides a method for preparing 10 new compounds from pleione bulbocodioides pseudobulb as a raw material for the first time, systematically evaluates the anti-neuroinflammation activity of pleione bulbocodioides pseudobulb, and clarifies the application of pleione bulbocodioides pseudobulb in development and treatment of central nervous system diseases. According to the invention, abnormally activated BV-2 microglial cells induced by LPS (Lipopolysaccharide) are adopted, and the NO release amount is taken as an index, so that the effect of the compound 1-10 on inhibiting excessive activation of the microglial cells is preliminarily evaluated. The result shows that the novel compounds 1-10 can inhibit the release of LPS-induced BV-2 microglial cell NO. Therefore, the compound prepared in the invention can be applied to development of drugs for treating central nervous system diseases.

The invention relates to the technical field of functional antioxidants, in particular to a stability-enhanced antioxidant based on pterostilbene and a preparation method and application thereof. The pterostilbene tablet comprises the following components in percentage by weight: 10-30% of pterostilbene, 8-20% of Arabic gum, 5-15% of tocopheryl succinate, 1-5% of disodium ethylene diamine tetraacetate, 30-60% of beta-cyclodextrin, 2-8% of rosmarinic acid, 1-6% of chitosan quaternary ammonium salt, 0.5-3% of nano silicon dioxide and 2-7% of polyglycerol fatty acid ester. In the preparation process, beta-cyclodextrin and pterostilbene form an inclusion compound, the dispersity of nano silicon dioxide and chitosan quaternary ammonium salt is improved through hydrogen bonds, and tea polyphenol or ascorbyl palmitate can be added to enhance the synergistic effect. The antioxidant is high in stability, high in pterostilbene retention rate, uniform in dispersion, free of agglomeration, excellent in antioxidant activity, suitable for the fields of foods, cosmetics and medicines, simple in preparation process, low in consumption and suitable for industrial production.

The invention provides a reduced coenzyme Q10 and gamma-aminobutyric acid eutectic crystal and a preparation method and application thereof, and belongs to the technical field of eutectic crystal manufacturing. In the eutectic crystal, the molar ratio of the reduced coenzyme Q10 to the gamma-aminobutyric acid is 1: 2, and the structural formula of the eutectic crystal is as shown in formula I. The eutectic crystal has the advantages of good stability, low cytotoxicity and strong oxidation resistance.

Systems and methods for producing MTBE are disclosed. A C4 feed stream containing isobutylene and other C4 hydrocarbons is fed into a reactor unit for producing MTBE. The effluent of the reactor unit comprising MTBE is further processed to produce a MTBE product stream that comprises at least 90 wt. % MTBE. At least a portion of the MTBE product stream is then recycled back to the reactor unit.

The invention belongs to the technical field of chemical production, and particularly relates to a novel process for separating pentaerythritol by a membrane method and application of the novel process. The membrane separation comprises the steps of separating sodium formate by using an ion exchange membrane and separating pentaerythritol by using a low-pressure nanofiltration membrane device. The dealdehyding liquid is separated through different membranes, and formic acid, pentaerythritol, dipentaerythritol and other substances can be effectively separated. The process greatly shortens the process flow and saves the cost. According to the technical scheme, the quality and performance of the pentaerythritol product are remarkably improved, the added value of the product is increased, and a new technical scheme is provided for industrial production of pentaerythritol.

The invention discloses a chlorphenesin coupling crystallization-adsorption purification method based on a deep eutectic solvent, and belongs to the technical field of chemical purification. According to the technical scheme, the method comprises the following steps: S1, mixing crude chlorphenesin with supercritical CO2, and extracting to obtain pretreated chlorphenesin; s2, dissolving the pretreated chlorphenesin in a choline chloride-glycerol DES system, adding an adsorbent after sufficient dissolution, cooling, and separating out chlorphenesin. The technical problems that an organic solvent is used in an existing chlorphenesin purification method, and the solvent is inflammable, toxic, large in dosage, long in purification time and high in energy consumption are solved, and the chlorphenesin coupling crystallization-adsorption purification method based on the eutectic solvent is safe, environmentally friendly, capable of improving production efficiency and high in product purity and yield.

The invention belongs to the technical field of medical analysis, and particularly relates to a method for separating chemical components in hemsley rockvine root. According to the present invention, various chromatography methods are adopted to carry out separation and purification, such that sitroside (I), vanillyl glycolII (II), 5-hydroxymaltol (III), vanillic acid (IV), afzelin (V), 2, 3-dihydroxypyrazole (9E, 11E)-13-hydroxypyrazole (9, 11-dienoate), and 2, 3-dihydroxypyrazole (10E, 12E)-9-hydroxypyrazole (10, 12-dienoate) are obtained from hemsley rockvine root. Wherein the compounds II, III, VI and VII are separated from the hemsley rockvine root for the first time, and development and quality control of the hemsley rockvine root medicinal material are facilitated.

The application discloses an EBR solvent and a rectification preparation process thereof, and belongs to the technical field of semiconductor material processing; wherein the EBR solvent comprises the following components in percentage: 95-98% of propylene glycol methyl ether acetate and 2-5% of propylene glyyl methyl ether. The EBR solvent is prepared by rectification recovery of waste liquid generated in a dilution cleaning process, and the main steps are as follows: S1, sedimentation filtration: filtering solid impurities in the waste liquid; S2, preliminary water removal: removing part of water in the filtered waste liquid through a common distillation tank to obtain primary waste liquid raw material; S3, feeding: introducing the primary waste liquid raw material into a rectification tower for intermittent distillation purification; S4, water removal: removing water in the primary waste liquid raw material by using an extractant; S5, extractant reflux; S6, extractant extraction: after the water is removed, the extractant is extracted; and S7, EBR solvent extraction. The application solves the problem that the purity of the effective component EBR solvent in the photoresist cleaning waste liquid is not high, and the recycling effect is poor.

The application discloses a method for reducing low-temperature turbidity of fatty alcohol polyether, and belongs to the technical field of fatty alcohol polyether preparation. The method comprises the following steps: heating and stirring the low-temperature turbid fatty alcohol polyether to be transparent, adding acid or alkali, stirring under the condition of heat preservation, adding an adsorbent, continuing to stir, increasing temperature to dehydrate, cooling, stirring after the dehydration is completed, and filtering under the condition of heat preservation and negative pressure. The method can significantly reduce the turbidity of the low-temperature turbid problem product or make the problem product not appear turbidity at low temperature by means of acid treatment or alkali treatment, adsorption and low-temperature filtration.

A method for producing a (poly)alkylene glycol monoalkyl ether includes reacting an olefin and a (poly)alkylene glycol in a reactor in a presence of a catalyst. The method also includes recovering at least a portion of raw materials used for the production to use the recovered raw materials again as a raw material, where at least one of the recovered raw materials contains an olefin. A mass of a branched olefin relative to a mass sum of the branched olefin and a linear olefin contained in the recovered raw materials is controlled not to exceed 20 mass %.

[Problem] The present invention provides a production method capable of producing a larger amount of DHMBA, which is an antioxidant, with a higher concentration from the clam meat of a bivalve of Pterioidea, which is, for example, Pinctada fucata or Isognomon ephippium, than from other bivalves, by heating or pressurizing the clam meat of Pinctada fucata or Isognomon ephippium. [Solution] The present invention is characterized by putting the clam meat of a bivalve belonging to Pterioidea in an extraction solution and heating the extraction solution, thereby making it possible to produce a larger amount of 3,5-dihydroxy-4-methoxybenzyl alcohol from the heat-treated clam meat of the bivalve belonging to Pterioidea than other bivalves.

The invention discloses a recovery method and application of ethylene glycol dimethyl ether, and belongs to the technical field of solvent recovery, and the recovery method comprises the following steps: mixing and stirring a recovery solvent and water, and standing for layering to obtain a lower water layer; distilling the water layer to obtain a distillation solvent; adding a dehydrating agent into the distillation solvent, stirring, and standing for layering to obtain supernatant liquid; and adding sodium filaments into the clear liquid for reaction, distilling and recovering ethylene glycol dimethyl ether. In conclusion, according to the recovery method and application of ethylene glycol dimethyl ether, through multi-step cooperative operation of extraction, distillation-alkaline dehydration and removal of tert-butyl alcohol from sodium filaments, accurate removal of impurities is achieved, the purity of solvent recovery in production of tert-butyl compounds is guaranteed, multiple targets of resource circulation, cost reduction and environmental protection standard reaching are achieved, and the recovery method and application of ethylene glycol dimethyl ether are suitable for industrial production. And a feasible technical scheme is provided for industrial sustainable production of the tert-butyl compound.

The application discloses a kind of miraculin compounds and its extraction method and application, belong to the field of traditional Chinese medicine extraction, specifically related to a kind of miraculin compounds as shown in general formula (I) and (II) isolated from Rhododendron dauricum and the extraction method of the compound, and the compound or the isomer of the compound, or the inhibitory effect of the compound on inflammation in pharmaceutically acceptable salt or pharmaceutical composition comprising the compound can be used for preparing anti-inflammatory drugs.The application further enriches the structural diversity of active substances of Rhododendron dauricum, which lays a foundation for subsequent related biological activity tests of monomeric compounds, provides active lead compounds for new drug development, and also provides a theoretical basis for in-depth research and development of Rhododendron dauricum medicinal materials.

The application discloses an adsorbent for removing trace metal ions in alcohol ether solvents and a preparation method and application thereof, and belongs to the field of chemical separation technology. The adsorbent is a zirconium-based metal organic cage material with discrete structure formed by coordination self-assembly of a zirconium metal salt and a nitrogen-containing polycarboxylic acid organic ligand. The adsorbent has specific ion nanowells, and can form a strong limited synergistic effect with metal ions. The adsorbent is suitable for adsorption and separation of trace metal ions in various alcohol ether solvents, and has high metal ion adsorption and removal efficiency.

To provide a process for the separation of at least one inositol from a carob extract.SOLUTION: This process comprises the steps of: a) providing a filtered and demineralised carob extract having a Brix value greater than 60 and a pinitol content, in weight percent based on the weight of the extract, from 5 to 25%; b) subjecting the carob extract of step a) to a process of chromatographic separation of the pinitol, wherein the process comprises subjecting the extract to at least one passage through a chromatographic resin, thus obtaining an aqueous solution having a pinitol content, in weight percent based on the total weight of the solution, from 35 to 70%, and which has a Brix value of 20 or lower; and c) subjecting the aqueous solution thus obtained in step b) to a purification step, thus obtaining a purified aqueous solution having a pinitol content, in weight percent based on the total weight of the solution, of more than 55%.SELECTED DRAWING: Figure 1

This application relates to the field of organic synthesis technology, specifically disclosing a process for preparing tert-butyl vinyl ether. The raw materials include solid tert-butanol, acetylene, tetrahydrofuran solvent, and potassium hydroxide catalyst, supplemented with auxiliary materials such as type 3A molecular sieves and activated alumina adsorbents. The preparation method involves: after dehydration and purification of the raw materials, the materials are introduced into a reaction vessel; temperature and pressure are controlled, and the reaction endpoint is monitored using an infrared spectrometer; byproducts are quenched and acetylene is recovered; the process involves multi-stage condensation, water washing to remove impurities, distillation separation, and solvent purification and recycling, with simultaneous integration of waste heat recovery and continuous material feeding. The tert-butyl vinyl ether prepared by this process, as an important fine chemical intermediate, can be used in coatings, adhesives, and polymer material modification, possessing advantages such as high purity and good stability. The preparation method achieves efficient utilization of materials and energy through multi-stage synergistic linkage, combining the advantages of green environmental protection, continuous and stable operation, and high resource utilization.

A system for producing ether includes a first etherification reactor system containing first catalyst and producing a first reaction effluent when supplied with alcohol and olefinic hydrocarbon feedstock, a second etherification reactor system containing second catalyst and producing a second reaction effluent when supplied with the first reaction effluent, and a distillation column receiving the second reaction effluent at a feed-point between the bottom and the top of the distillation column. The produced ether is taken out from the bottom of the distillation column. Volume of the first catalyst contributing the production of the first reaction effluent is at most 15% of total volume of the first catalyst and the second catalyst contributing the production of the second reaction effluent. The first etherification reactor system acts as a guard-bed reactor which removes unwanted components from the feed and thus protects the second etherification reactor system.

A method for supplying deaerated water to a chemical plant, wherein the chemical plant includes a distillation column for separating a reaction effluent including water and a product. The method includes charging aerated water (water having an oxygen content greater than 50 ppbw, such as greater than 1 ppmw) to the distillation column. The aerated water in the distillation column can then be distilled to produce an oxygen-containing overhead and a bottoms fraction including deaerated water. The deaerated water in the bottoms fraction can be transported to and utilized in upstream or downstream unit operations. The reaction effluent is fed to the distillation column, converting the distillation column from an operation that separates oxygen from water to an operation that separates the product from water.

In order to overcome the problems of high recovery price, high energy consumption and low utilization rate of the existing kettle residue for the production of ethylene glycol by ethylene carbonate alcoholysis method, the application provides a kettle residue recovery method and device for the production of ethylene glycol by ethylene carbonate alcoholysis method, and the application provides a kettle residue recovery method for the production of ethylene glycol by ethylene carbonate, which comprises the following steps: under the conditions of temperature 150-250 DEG C and pressure 0.6-2 MPa, the ethylene glycol in the kettle residue produced by the preparation of ethylene glycol by ethylene carbonate alcoholysis method is converted into diethylene glycol under the catalysis of alkali metal salt catalyst, and after the reaction is completed, the kettle residue is a mixture of ethylene glycol, diethylene glycol, triethylene glycol and salt, the mixture is purified, and ethylene glycol and diethylene glycol are recovered; the economic benefit is improved, the rectification separation operation is simplified, the equipment investment and the overall energy consumption are reduced, and the utilization rate of ethylene glycol kettle residue is improved.

The invention discloses a method for preparing p-trifluoromethoxyphenol by adopting a micro-channel reactor, and belongs to the field of fine chemical engineering. 4-trifluoromethoxyaniline and dilute sulphuric acid are pumped into the first micro-channel reactor for a reaction; then introducing inert gas, pumping the nitroso sulfuric acid solution, and carrying out diazotization reaction to obtain a diazonium salt solution; pumping the diazonium salt solution into a second micro-channel reactor, carrying out hydrolysis reaction, adding dichloroethane extract liquor into a rectifying tower after the reaction is ended, and rectifying to obtain p-trifluoromethoxyphenol; porous baffles which are inclined downwards are arranged on the inner wall of the rectifying tower in a crossed manner; a heat-conducting filler layer of 50-100 nm is arranged on the porous baffle plate; the heat-conducting filler layer is a three-dimensional net-shaped material layer which is formed by boron nitride nanosheets / titanium oxide nanorods and has a porous structure. The method is simple in process route, convenient to operate, high in controllability, high in safety, high in reaction efficiency, high in product yield, capable of effectively reducing the solid waste amount in production, energy-saving, environment-friendly and suitable for industrial production.

The utility model belongs to the technical field of methyl tert-butyl ether cracking, and particularly relates to a device for producing isobutene by cracking methyl tert-butyl ether. The device for producing isobutene by cracking methyl tert-butyl ether comprises an MTBE refining tower, the MTBE refining tower is connected with a cracking reactor, the bottom of the cracking reactor is sequentially connected with a condensate water cooler and a circulating water cooler, the circulating water cooler is connected with an absorption cooling tower, the absorption cooling tower is connected with a compressor inlet buffer tank, and the compressor inlet buffer tank is connected with a compressor outlet buffer tank. The compressor inlet buffer tank is connected with the gas production compressor; and the gas production compressor is connected with the isobutene water washing tower. According to the device for producing isobutene by cracking methyl tert-butyl ether, the condensate water cooler and the circulating water cooler are arranged and are matched with the light component removal tower reboiler, so that the cyclic utilization of heat is realized, and the energy consumption of the device is reduced; meanwhile, the isobutene water washing tower and the methanol water collecting tank are arranged, so that the loss of methanol is reduced, and the purity of an isobutene product is improved.

The invention relates to a process for preparing an alkoxylated product. The aim of the invention is to provide aromatic polyols for preparing polyurethane-based and polyisocyanurate-based polymers, which ensure good miscibility with the isocyanate component and other components, have a good storage stability and render the end product flameproof. For this purpose, the invention devises a process for preparing an alkoxylated product by reacting bisphenol F with propylene carbonate and / or propylene oxide as propoxylation agent and ethylene carbonate and / or ethylene oxide as ethoxylation agent, the propoxylation agent and the ethoxylation agent being used in a molar ration of 70:30 to 45:55.

A system for producing ether includes a processing system that receives alcohol and olefinic hydrocarbon feedstock and includes a first etherification reactor system that produces a first reaction effluent. A distillation column system receives a mixture containing the first reaction effluent to produce ether. A side flow outlet withdraws a side flow from the distillation column system and a second etherification reactor system receives the side flow and produces a second reaction effluent. The second reaction effluent is mixed with the first reaction effluent, and this mixture is supplied to the distillation column system. The side flow makes it possible to produce a given amount of ether with a smaller amount of catalyst material.

The invention belongs to the technical field of rectification of dipropylene glycol, and relates to a rectification process of dipropylene glycol. The process comprises the following steps: preheating a crude product raw material containing dipropylene glycol, then feeding the crude product raw material into a pre-separation tower for pre-rectification, then feeding tower bottoms of the pre-separation tower into a packed tower for rectification, and extracting from the tower top of the packed tower to obtain a dipropylene glycol product; the interior of the packed tower is sequentially filled with modified ceramic corrugated packing, a stainless steel wire net and modified molecular sieve packing from bottom to top; the modified ceramic corrugated filler is obtained by sequentially acidizing a ceramic corrugated filler and loading SiO2 / CeO2; the modified molecular sieve filler is obtained by alkalization, calcination and SiO2 / Al2O3 loading of molecular sieve honeycomb ceramics in sequence. Through the modified ceramic corrugated filler, the stainless steel wire mesh and the modified molecular sieve filler which are sequentially arranged from bottom to top, the material transfer efficiency, the component separation precision and the operation stability of the device in the crude product raw material rectification process are optimized, and the overall process efficiency is effectively improved.

The present invention provides a reduced coenzyme Q10 crystal which, when measured by means of differential scanning calorimetry at a heating rate of 10 k / min, exhibits an endothermic peak at 52±2°C. Compared with the prior art, the crystal form of reduced coenzyme Q10 provided by the present invention is more stable than reduced coenzyme Q10 crystals reported in the literature, and other physical properties, including water solubility and residual solvents, are also superior; in addition, the crystal form provided by the present invention also overcomes the disadvantages of previously known reduced coenzyme Q10, which is very easily oxidized and has limitations in use; furthermore, the reduced coenzyme Q10 crystal and a crystalline solid containing the crystal provided by the present invention not only have excellent physical properties in terms of stability, but also stand out in terms of high purity and low solvent residue.

A process for making hydrofluoroethers, the process comprising: •A) providing a mixture comprising one more polar aprotic organic solvents having a boiling point measured at 1 atm (1.01 bar) of from 60° C. to 170° C. and one or more chemical compounds carrying at least one —OH group which is part of an alcohol or of a phenol group, and •B): reacting said one or more chemical compounds carrying at least one —OH group with one or more fluorinated olefin in the presence of a basic catalyst thus providing a reacted mixture comprising one or more hydrofluoroethers.

The invention relates to the technical field of separation and purification, in particular to a method for preparing eugenol from clove oil plants, which comprises the following steps: (a) mixing clove buds or leaves with perlite according to a mass ratio of 1: (1.5-2) to obtain a mixture; (b) an anti-oxidation composite liquid is added into the mixed material, the mixture is stirred to be uniform and then left to stand, a pretreated material is obtained, and the anti-oxidation composite liquid comprises ascorbic acid, citric acid and glycerin; (c) loading the pretreated material into a distillation device, carrying out gradient heating steam distillation, and collecting condensate; (d) performing low-temperature vacuum concentration on the condensate to obtain crude eugenol; and (e) mixing the crude eugenol with a molecular sieve according to a mass ratio of 1: (3-5), adsorbing, and filtering to obtain refined eugenol. The invention provides an efficient, stable and environment-friendly eugenol purification method, by introducing a novel protective agent system and a staged temperature control rectification technology, the occurrence rate of thermal decomposition and oxidation reaction is remarkably reduced, and the product purity and the production efficiency are improved.

The application provides a preparation method of Zr-BDC film and application of the Zr-BDC film in separation of organic matters. The application directly uses zirconium propoxide as the only zirconium source in a mother liquor, and continuously synthesizes Zr-BDC film through a solvothermal method; the content of the metal source in the mother liquor is extremely low, so that the film thickness is still thin after three times of solvothermal growth, and the preparation of a high-flux film is facilitated. The application uses a ligand / metal molar ratio of up to 20, and provides application of the Zr-BDC film with less defect sites in separation of MeOH / MTBE. The Zr-BDC film prepared by the application exhibits optimal separation performance of MeOH / MTBE, and when 5wt.% MeOH / MTBE is separated at 40 DEG C, the film flux can reach 5.68kg·m ‑2 ·h ‑1 -1h-1, the separation factor is up to 25802, and the operation stability is greater than 5 days.

The present disclosure provides a method for producing a composition comprising a purified fluorine-containing ether compound represented by formula (1): CHX1X2CF2OX3, wherein X1 and X2 are the same or different and each represents a hydrogen atom, a fluorine atom, or a trifluoromethyl group, and X3 represents a C1-6 alkyl group, provided that not both X1 and X2 are trifluoromethyl groups.

The present invention addresses the problem of providing a method for efficiently producing a crystal of a compound A1, said method being suitable for industrial mass production, and enabling rapid crystallization in a crystallization step. As a solution, provided is a method for producing a crystal of a phenol compound having a methoxymethyl group represented by chemical formula (A1), the method being characterized by comprising a crystallization step, and a crystallization step in which crystals are precipitated from a solution containing a phenol compound having a methoxymethyl group represented by chemical formula (A1), a C3-4 chain aliphatic alcohol solvent, and a C6-8 aliphatic hydrocarbon solvent.