385 results about "Coenzyme Q10" patented technology

The invention discloses an ovarian protection composition containing ergothioneine and a preparation method of the ovarian protection composition, and relates to the technical field of ovarian protection compositions. The ovary protection composition containing the ergothioneine is prepared from the following components in parts by mass: 0.1 to 0.5 part of the ergothioneine, 0.05 to 1 part of S-equol, 1 to 5 parts of reducing coenzyme Q10, 1 to 3 parts of vitamin E, 10 to 20 parts of chitosan oligosaccharide, 30 to 50 parts of microcrystalline cellulose, 3 to 8 parts of hydroxypropyl methyl cellulose, 0.5 to 2 parts of silicon dioxide and 0.5 to 2 parts of a stabilizer. By adopting the stabilizer, photooxidation and hydrolysis of sensitive components are inhibited through molecular action, and the long-term stability of the composition in a humid and hot environment is remarkably improved in combination with the physical barrier action of silicon dioxide. Through the antioxidant synergistic effect of the ergothioneine and the vitamin E, the hormone regulation effect of the S-equol and the energy metabolism improvement effect of the coenzyme Q10, a multi-layer ovarian function protection system is constructed, and the health state of ovaries is improved. Through a special process, the tablet can be rapidly disintegrated and slowly released in an intestinal targeted manner, burst release of active ingredients is avoided, and the absorption efficiency is improved.

The invention discloses a coenzyme Q10 soft capsule appearance defect detection method based on image recognition, relates to the technical field of capsule detection, and solves the problem that the reliability and pertinence of a detection result are insufficient due to the fact that different types of defects such as size deviation and breakage wrinkles cannot be effectively recognized. According to the method, the standard image and the to-be-analyzed image set are determined from a large number of images, and then the image with the most significant difference between the to-be-analyzed features and the focus is selected for ellipse perimeter comparison; according to the mode, the analysis range can be efficiently narrowed, the area where wrinkles, damage or abnormal sizes possibly exist can be accurately positioned, and the pertinence and efficiency of defect analysis are improved.

The invention discloses an endogenous anti-aging composition based on an internal and external synergistic mechanism and a preparation method of the endogenous anti-aging composition. The endogenous anti-aging composition based on the internal and external synergistic mechanism is prepared from the following components in parts by mass: 100 to 200 parts of alpha-ketoglutarate calcium; 100 to 200 parts of an olive leaf extract; 10 to 20 parts of nicotinic acid; 10 to 20 parts of pyrroloquinoline quinone; 20 to 60 parts of pomegranate extract; and 10 to 30 parts of coenzyme Q10. The composition and the preparation method thereof have the beneficial effects that the composition capable of integrally improving the aging state of women from multiple dimensions and the preparation method of the composition are provided.

The invention discloses a coenzyme Q10-containing medicine for improving heart activity and a preparation method thereof, and particularly belongs to the technical field of biological medicines. The medicine comprises functional components and auxiliary materials, wherein the functional components comprise a cactus extract, a calligonum mongolicum extract, an astragalus membranaceus extract, a sea-buckthorn extract and coenzyme Q10; the hypoxia survival time and the load-bearing swimming time of mice can be remarkably prolonged through low, medium and high dose groups of the medicine for improving the heart vitality, the requirement of fatigue caused by high labor intensity for oxygen is further met by enhancing the immunity of the organism, supply of nutrient substances to the brain, the heart, the bones and the muscles of the organism is enhanced, and the effect of improving the heart vitality is achieved. The composition can regulate the activity of central nervous system, promote the normal operation of the body circulation system, relieve and eliminate fatigue and damage to the body caused by fatigue and chronic fatigue, and quickly recover physical strength.

The invention discloses an oral instant film suitable for pet nutrition intervention and a preparation method of the oral instant film, and belongs to the technical field of pet oral preparations. The instant film adopts a sandwich type multi-layer structural design, sequentially comprises a first food calling layer, a core layer and a second food calling layer, can be selectively provided with a functional layer and an interface middle layer, and constructs a staggered hot-pressing laminated structure, so that the structural stability and the function delivery efficiency of a film body are remarkably improved. The core layer contains multiple composite active ingredients such as L-carnitine, coenzyme Q10, beta-glucan, glucosamine sulfate and the like, chitosan-inulin-polyglutamic acid or starch is adopted for embedding to form a first microcapsule and a second microcapsule, and intelligent delivery of temperature / pH response and gastrointestinal controlled release is achieved. The food calling layer is composed of chicken powder, fish oil powder, fructo-oligosaccharide and the like, and the feeding compliance of pets is improved.

The invention relates to the technical field of oral solid preparations, in particular to a high-bioavailability coenzyme Q10 tablet and a preparation method thereof. The coenzyme Q10 tablet comprises an active component coenzyme Q10, a filler, an adhesive, a disintegrating agent, a lubricant and a high polymer material, compared with the prior art, hydroxyethyl methylcellulose and hydroxypropyl methylcellulose succinate are mixed according to a certain mass ratio to serve as a high polymer carrier material, the prepared coenzyme Q10 tablet can be rapidly dissolved out in vitro, and the coenzyme Q10 tablet has the advantages that the preparation process is simple, and the cost is low. Moreover, the stability of the medicine can be improved, the medicine can be rapidly absorbed in vivo after being orally taken, the oral bioavailability of the coenzyme Q10 is greatly improved, and a preparation process of the preparation is simple to operate, good in reproducibility and suitable for industrial production.

The invention discloses an ergothioneine composition with an anti-aging function, and relates to the field of health-care foods, and the composition has the effects of resisting aging and cell molecule oxidation reaction. The composition disclosed by the invention is prepared from the following composition components: ergothioneine (0.162 to 0.185), a wheat germ extract (0.063 to 0.085), coenzyme Q10 (0.042 to 0.063), quercetin (0.35 to 0.55), a turmeric extract (0.032 to 0.054), a black pepper extract (0.003 to 0.006) and aminobutyric acid (0.205 to 0.227). The composition is used for assisting body functions in eliminating lipid, protein, DNA (deoxyribonucleic acid) and the like in cells damaged by oxidative stress in a body. The composition is prepared into equivalent particles by fully and physically stirring and uniformly mixing, is convenient for human body to absorb, and can remarkably improve the antioxidant capacity and delay the aging process after being taken for a long time. The composition not only can effectively resist oxidative stress disoperation, but also can promote cell repair. The raw materials of the composition can be purchased in the market, and the composition is high in production benefit and beneficial to wide application.

The invention discloses a coenzyme Q10 phospholipid-cyclodextrin double-layer inclusion compound and a preparation method thereof, and particularly relates to the technical field of food raw materials. A preparation form of double-layer inclusion of phospholipid on the inner layer and cyclodextrin on the outer layer is adopted, so that the solubility and bioavailability of the coenzyme Q10 are remarkably improved, and good stability is shown. Meanwhile, the preparation process is simple, the used organic solvent is relatively safe and single, and the method is suitable for industrial mass production.

The invention discloses an anti-aging composition containing PQQ and a preparation method of the anti-aging composition, and belongs to the field of medicines or health food, the anti-aging composition comprises PQQ, an antioxidant, collagen, hyaluronic acid and a plant extract, and the content of PQQ is 0.1-5%; 1%-10% of collagen; 0.05%-2% of hyaluronic acid; the antioxidant comprises the following components in percentage by weight: 0.5%-5% of vitamin C, 0.1%-3% of alpha-tocopherol and 0.05%-2% of beta-carotene; the composition contains PQQ and various antioxidants such as vitamin C, alpha-tocopherol, beta-carotene, coenzyme Q10 and glutathione, and the components have a synergistic effect, so that free radicals can be effectively removed, oxidative damage can be reduced, and cell aging can be delayed; most of the components in the composition are natural substances or are widely applied to the fields of food and health care products, the safety is high, and the quality and safety of the product can be ensured through the steps of strict preparation process control, accurate component dissolving method, pH value adjustment, filtration and the like.

The invention discloses a composition containing D-chiro-inositol as well as a preparation method and application of the composition. The composition comprises D-chiro-inositol, Myo-inositol and microcapsule powder, wherein the wall material of the microcapsule powder consists of anhydride modified edible protein and a polysaccharide compound; the edible protein is selected from at least one of spirulina protein, quinoa protein, whey protein and soybean protein; the polysaccharide compound comprises at least one of fucoidin and larch arabinogalactan. Active components are also embedded in the microcapsule powder, and comprise at least one of Omega-3, coenzyme Q10, astaxanthin and vitamin. According to the composition, the stability and bioavailability of fat-soluble active ingredients are improved through microencapsulation, and the composition has a synergistic effect with components such as D-chiro-inositol and Myoinositol, so that insulin resistance is effectively improved, female hormone balance is adjusted, and polycystic ovarian syndrome is improved. The process is simple, is suitable for large-scale production, and can be widely applied to dietary supplements or functional foods.

The invention provides a reduced coenzyme Q10 eutectic crystal as well as a preparation method and application thereof. The eutectic crystal is prepared from the reduced coenzyme Q10 and L-lysine. Compared with the prior art, the prepared reduced coenzyme Q10 eutectic can effectively improve the stability of the reduced coenzyme Q10, and widens the solid existence form of the reduced coenzyme Q10. The preparation method of the reduced coenzyme Q10 eutectic crystal provided by the invention is simple, low in cost, convenient for large-scale production and favorable for subsequent product development, and particularly has important value for developing a reduced coenzyme Q10 solid oral preparation in the future.

The invention relates to the technical field of biologic stimulant preparation, and discloses a biologic stimulant mixing preparation two-stage control method, which comprises: adopting dissolved oxygen gradient and carbon source pulse cooperative control, linearly reducing the concentration of dissolved oxygen in a fermentation tank from an initial value at a specific rate, and injecting a carbon source at regular time; when the flora density and the quorum sensing signal molecule concentration reach specific threshold values, triggering stage switching; starting pressure-metabolism coupling control, increasing the pressure of the fermentation tank at a specific rate, and adding coenzyme Q10; the quorum sensing inhibitory peptide containing a specific core structure is synchronously released in the boosting process; after the pressure is stable, a real-time mapping relation between a microbial metabolism state and physical parameters is constructed in a thallus proliferation stage through a coupling mechanism of dissolved oxygen gradient control and quorum sensing signal monitoring, and the industrial problem that a traditional static threshold value cannot respond to pressure fluctuation of a fermentation tank to cause signal attenuation is solved.

The invention relates to an anti-aging composition containing recombinant collagen and a preparation method thereof. The main component of the composition is high-purity collagen obtained through a gene recombination technology, and various anti-aging active components such as sodium hyaluronate, vitamin C, coenzyme Q10 and vitamin E are combined. The invention also provides a preparation method, which ensures that each component is uniformly distributed and the biological activity is not damaged through low-temperature homogenization treatment and accurate proportioning. The composition disclosed by the invention can be used for remarkably promoting the proliferation of human skin fibroblasts and enhancing the expression of I-type collagen genes, and has a remarkable anti-aging effect. The composition is high in safety and remarkable in effect, is suitable for preventing and treating skin aging, and is widely applied to the fields of medicines and cosmetics.

The present invention provides a nutritional composition with coenzyme CoQ10 as a main component, a preparation method of the composition, and an application of the composition.

The invention provides a reduced coenzyme Q10 and gamma-aminobutyric acid eutectic crystal and a preparation method and application thereof, and belongs to the technical field of eutectic crystal manufacturing. In the eutectic crystal, the molar ratio of the reduced coenzyme Q10 to the gamma-aminobutyric acid is 1: 2, and the structural formula of the eutectic crystal is as shown in formula I. The eutectic crystal has the advantages of good stability, low cytotoxicity and strong oxidation resistance.

The invention belongs to the technical field of cosmetics, and particularly relates to a silk fibroin aggregate-based dispersed organic active substance as well as a preparation method and application thereof. The preparation method of the silk fibroin aggregate-based dispersed organic active substance comprises the following steps: (1) dissolving an organic active substance in a first solvent to obtain a first solution; dissolving the silk fibroin aggregate in a second solvent to obtain a second solution; (2) slowly adding the second solution into the first solution, mixing and homogenizing to obtain a silk fibroin aggregate-based dispersed organic active substance; wherein the silk fibroin aggregate is prepared by mixing a silk fibroin aqueous solution and alcohol. The silk fibroin aggregate-based dispersed organic active substance prepared by the preparation method can improve the bioavailability of the organic active substance (such as vitamin C, hyaluronic acid, coenzyme Q10, nicotinamide, arbutin, kojic acid, licorice extract, centella extract, chamomile extract or green tea extract) in cosmetics.

The invention provides a culture medium for gamma delta T cells and a culture method of the gamma delta T cells, and belongs to the technical field of cell culture. According to the culture medium of the gamma delta T cells, OpTmizer serves as a basic culture medium, and the OpTmizer culture medium further contains IL-2 with the concentration being 150-250 IU / mL, IL-6 with the concentration being 40-60 [mu] mol / L, vitamin C with the concentration being 40-60 [mu] mol / L, vitamin B3 with the concentration being 8-12 [mu] mol / L and coenzyme Q10 with the concentration being 3-7 [mu] mol / L. The prepared gamma delta T cell culture medium is used for culturing gamma delta T cells with improved killing activity, and the killing rate of the cultured gamma delta T cells on A549 cells and HepG2 cells can be remarkably improved.

The present invention relates to the technical field of dietary supplements, and more particularly to a composition formulation having an NMN anti-aging effect and a preparation method thereof. Technical Problem: the composition formulation having an NMN anti-aging effect and the preparation method thereof aim to solve the technical problem of not being able to enhance the body's resistance while also having an anti-aging effect, making the patient's body more energetic. Technical Solution: a composition formulation having an NMN anti-aging effect, including the following components: NMN 300 mg, PQQ 10 mg, coenzyme Q10 20 mg, ginsenoside 70 mg, aminobutyric acid 100 mg, other beneficial ingredients q. s.

The invention relates to a multi-enzyme synergistic skin care composition suitable for sensitive skin and application thereof, the skin care composition comprises the following components: crithmum maritimum extract, pomegranate peel extract, lysozyme and coenzyme Q10, the crithmum maritimum extract is obtained by anaerobic fermentation of crithmum maritimum through leuconostoc mesenteroides and lactobacillus plantarum and is rich in SOD enzyme; the pomegranate peel extract is obtained by performing anaerobic fermentation on pomegranate fruits through lactobacillus helveticus and is rich in protease and lipase. The crithmum maritimum extract, the pomegranate peel extract, the lysozyme and the coenzyme Q10 are compounded for use, a multi-dimensional synergistic skin care system is constructed, and repairing, anti-inflammatory and anti-aging integrated efficient improvement is achieved.

The invention provides methods and compositions for treatment of a subject with a glioma. The methods comprise administering a composition comprising Coenzyme Q10 to the subject by continuous intravenous infusion; and administering radiation therapy to the subject. The composition comprising Coenzyme Q10 may be administered to the subject by continuous intravenous infusion for at least 24 hours before the radiation therapy is initiated.

The invention relates to an anti-aging capsule compounded by PQQ and mitochondrial nutrients, and discloses an anti-aging capsule which is prepared by synergistically compounding a plurality of mitochondrial nutrients according to a scientific proportion and supplementing high-purity raw materials and slow-release dosage forms to realize energy metabolism activation and anti-oxidation synergistic intervention. Therefore, the anti-aging capsule systematically delays aging through multi-target regulation and control of mitochondrial functions. The capsule is characterized by comprising the following components in parts by weight: 1-20 mg of pyrroloquinoline quinone disodium salt (PQQ), 20-100 mg of coenzyme Q10, 50-200 mg of L-carnitine tartrate, 10-100 mg of alpha-lipoic acid, 50-300 mg of nicotinamide mononucleotide (NMN) or nicotinamide nucleoside (NR), and 10-50 [mu] g of selenoprotein or organic selenium yeast, and a capsule carrier comprises 100 mg of gelatin or a plant-derived capsule shell, 180 mg of microcrystalline cellulose, 5 mg of magnesium stearate and 5 mg of silicon dioxide.

The invention relates to the technical field of health food, in particular to a nervonic acid nutrient composition for relieving sleep disorder and application of the nervonic acid nutrient composition for relieving sleep disorder. The active components comprise natural vegetable oil such as acer truncatum seed oil purified nervonic acid, linseed oil and the like and gamma-aminobutyric acid extracted by fermentation; the synergistic component is prepared from soybean enzymolysis phosphatidylserine, saccharomycetes fermentation coenzyme Q10 and plant source B vitamins; the slow-release carrier adopts pectin-Arabic gum composite gel and plant starch to form a natural cross-linked structure, and long-acting release for 8-12 hours is realized through physical cross-linking. Green technologies such as ultrasonic dispersion and low-temperature drying are adopted in the preparation process, and chemical synthesis steps are avoided; the composition can improve the difficulty in falling asleep and improve the sleep quality, the activity retention rate is greater than or equal to 85% after the composition is stored at 45 DEG C for 6 months, and the composition is suitable for preparing capsules, gel candies and other health-care foods and has no dependence after being taken for a long time.

The invention discloses a composition containing NMN and a preparation method and application thereof. The composition provided by the invention comprises any two or more of NMN, coenzyme Q10, pyrroloquinoline quinone, resveratrol, plant fiber and glutathione. The invention unexpectedly discovers that the combination of two or more of NMN, coenzyme Q10, pyrroloquinoline quinone, resveratrol, plant fiber, glutathione and gamma-butylamine shows a beneficial synergistic effect in improving the NAD + level in vivo compared with a single component only applying pure NMN. Moreover, this synergy may result in additional benefits in therapy, such as anti-aging, enhancing immunity, resisting oxidation, protecting nerves, improving sub-health status, improving patient compliance, and the like. Meanwhile, no side effect is generated after long-term taking, and the conditions of body tolerance, drug effect absorption reduction and the like caused by long-term taking are also avoided.

The invention relates to the technical field of kidney-nourishing tea bag preparation, and discloses a preparation method of a medicinal and edible Chinese wolfberry kidney-nourishing tea bag, which comprises the following ingredients: 30% of Chinese wolfberry, 10% of bearberry leaf, 10% of uncaria, 10%-10% of cornu cervi pantotrichum, 10%-5% of coenzyme Q, 5% of omega-3 fatty acid powder, 10% of honey powder and 5% of sodium citrate. According to the preparation method of the medicinal and edible Chinese wolfberry kidney-nourishing tea bag, active ingredients in Chinese wolfberry fruits and bearberry leaves are extracted by using supercritical CO2, more organic acids and bioactive substances can be extracted under relatively mild conditions (low temperature and oxygen-free), the loss of heat-sensitive substances is reduced, and the medicinal and edible Chinese wolfberry kidney-nourishing tea bag is prepared by combining water extraction and an ultrasonic-assisted technology. The extraction rate of water-soluble components in the uncaria and the cornu cervi pantotrichum is improved, ultrasonic waves can break plant cell walls and improve the extraction rate and speed, the coenzyme Q10 and the omega-3 fatty acid powder are coated through microencapsulation treatment, the formed stable microcapsule can be gradually released in the body of a consumer, and the stability and bioavailability of the microcapsule are improved.

This invention discloses a cardioprotective compound composition and its preparation based on improving the absorption rate of coenzyme Q10, relating to the fields of pharmaceuticals and functional foods. The core active ingredients of this composition consist of coenzyme Q10, vitamin E, and black pepper extract, with a specific mass ratio range for each. It can also be combined with pharmaceutically acceptable carriers and antioxidant synergists to prepare various oral formulations. This invention, through the construction of a ternary active component with a specific ratio, achieves in vivo synergistic effects on absorption promotion and antioxidant regeneration, solving the technical problems of low oral bioavailability and insufficient accumulation of myocardial-targeted activity in existing coenzyme Q10 preparations. It significantly improves the conversion efficiency of coenzyme Q10 into a usable active form for cardiomyocytes and can be widely applied in the preparation of drugs and functional foods for the prevention or treatment of heart diseases.

The invention belongs to the technical field of food, and particularly relates to a composition formula for nourishing and protecting heart. The composition formula comprises the following raw materials: 3-8 parts of pulp of dogwood fruit, 2-6 parts of oyster, 2-5 parts of longan, 2-11 parts of spina date seed, 2-8 parts of platycladi seed, 3-5 parts of hawthorn, 10-12 parts of malt, 2-11 parts of raw endothelium corneum gigeriae galli, 3-5 parts of donkey-hide gelatin, 2-3 parts of codonopsis pilosula, 8-9 parts of sea cucumber, 1-3 parts of ginseng, 1-3 parts of pseudo-ginseng, 5-6 parts of astragalus membranaceus, 12-13 parts of liquorice, 13-15 parts of peach kernel, 1-5 parts of ginkgo, 3-5 parts of houttuynia cordata, 1-3 parts of lily and 0.8-1 part of fish oil. The green tea composition is prepared from the following raw materials in parts by weight: 10-11 parts of green tea, 0.5-0.7 part of coenzyme Q10, 0.6-0.7 part of vitamin D and 0.2-0.3 part of fruit extract, the preparation raw materials are easy to obtain, the raw materials are cheap, the preparation process is simple, and complicated operation steps are avoided, so that the cost can be effectively controlled, effective components of the raw materials are reserved, and the fruit extract is added into the prepared composition, so that the bitter taste of traditional Chinese medicines can be effectively improved; the drinking taste of the composition is improved.

The invention discloses a functional additive composition for animal food. The functional additive composition is prepared from coenzyme Q10, glutamic acid, galactooligosaccharide, fructus lycii powder and the balance of food-grade carrier. The components of the composition cooperate with each other, so that the composition can support the effects of enhancing the physique vitality of animals, promoting nutrient absorption, helping to maintain a healthy intestinal environment and the like, has remarkable innovativeness and practicability, and is expected to create good benefits in the field of animal foods. The invention can be used in economic animals and pet animals.

The invention discloses an anti-inflammatory and anti-aging body lotion and a preparation method thereof, and relates to the technical field of skin care products. The preparation method comprises the following steps: firstly, carrying out oxidation treatment on beta-cyclodextrin by using sodium periodate, and introducing an active aldehyde group on a glucose unit of the beta-cyclodextrin, so as to form aldehyde beta-cyclodextrin with a unique function; the cavity structure of the beta-cyclodextrin has efficient embedding capacity, and the hydrophobic coenzyme Q10 can be tightly wrapped in the beta-cyclodextrin; the preparation method comprises the following steps: grafting adipic acid dihydrazide onto a hyaluronic acid skeleton to form hydrazinized hyaluronic acid with reaction activity; the hyaluronic acid is subjected to specific cross-linking reaction with aldehyde beta-cyclodextrin through hydrazino on the surface of the hyaluronic acid, a micro-capsule structure with a dynamic covalent bond-hydrazone bond is formed, a three-stage delivery mode of stable storage, intelligent release and accurate action is formed, active ingredients can be effectively protected, intelligent release can be achieved according to the pH value characteristic of skin, and the skin care effect is achieved. The inflammatory reaction is relieved, and the anti-inflammatory and anti-aging effects are achieved. The body lotion prepared by the invention has anti-inflammatory and anti-aging effects.

The present invention relates to a liquid-phase, supplementary feed composition containing coenzyme Q10 and, more specifically, to a liquid-phase, supplementary feed composition containing coenzyme Q10, conjugated linoleic acid, fructooligosaccharide, L-carnitine, and taurine at specific contents, whereby the composition can prevent aging and onset of cardiovascular diseases and cardiac disease, activate the immune system, and provide a diet effect in companion animals.

The application provides a coenzyme Q10-producing genetically engineered bacterium and application thereof.