7results about How to "Regulate immunity" patented technology

The invention belongs to the technical field of food, and relates to application of breast milk oligosaccharide in regulating brain immunity. Specifically, the invention relates to the non-therapeutic purpose of adjusting brain immunity by adjusting polarization of microglial cells M1 / M2, and the breast milk oligosaccharide is any one of 3-fucosyllactose, lactose-N-tetraose, lactose-N-neotetraose, 3 '-sialic acid lactose and 6'-sialic acid lactose. Research results show that a specific variety of breast milk oligosaccharides (especially 3-FL) can obviously inhibit the generation of neurotoxic factors NO, inflammatory factors TNF-alpha and IL-1beta in microglial cells, and promote the generation of anti-inflammatory cytokines IL-10 in the microglial cells, so that the state of the microglial cells is improved, damage repair is promoted, and the microglial cells are prevented from being damaged. Therefore, the effect of regulating brain immunity is achieved.

The invention relates to application of a microbial preparation in preparation of a product for improving poultry production performance. Strain in the microbial preparation comprises pediococcus acidilactici PA153 and bacillus coagulans BC66. The classification name of the pediococcus acidilactici PA153 is pediococcus acidilactici, the preservation number of the pediococcus acidilactici PA153 is CCTCC (China Center For Type Culture Collection) No: M2023230, and the preservation date of the pediococcus acidilactici PA153 is March 2, 2023. The bacillus coagulans BC66 is classified and named as bacillus coagulans, the preservation number of the bacillus coagulans BC66 is CGMCC (China General Microbiological Culture Collection Center) No.21879, and the preservation date of the bacillus coagulans BC66 is March 8, 2021. The pediococcus acidilactici PA153 and the bacillus coagulans BC66 provided by the invention are combined for use and are mutually matched for synergistic interaction, so that the production performance of the poultry can be improved, and meanwhile, the pediococcus acidilactici PA153 and the bacillus coagulans BC66 can also be used for remarkably regulating the immunocompetence, promoting the development of immune organs, slowing down the atrophy speed of bursa of Fabricius and improving the humoral immune level of the poultry.

The invention discloses a composite probiotic preparation for treating secretory otitis media, comprising: kumiss-like lactobacillus, long bifidobacterium and other acceptable drugs or food excipients. The kumiss-like lactobacillus is kumiss-like lactobacillus ZW3, which has been deposited in the strain collection center of the Institute of Microbiology, Chinese Academy of Sciences on December 18, 2008, with a deposit number of CGMCC2809. The long bifidobacterium is preferably CGMCC 15014. The composite probiotic preparation of the invention has precise ingredients and is safe, and is particularly effective in treating secretory otitis media.

The invention discloses a strain of lactobacillus plantarum and application thereof, the lactobacillus plantarum is named as lactobacillus plantarum SMU5928 and is preserved in the China Center for Type Culture Collection (CCTCC), the preservation number is CCTCC NO: M2024731, and the preservation date is April 19, 2024. The lactobacillus plantarum has the advantages that the lactobacillus plantarum is named as the lactobacillus plantarum SMU5928, the lactobacillus plantarum is preserved in the China Center for Type Culture Collection (CCTCC), and the preservation number is CCTCC NO: M2024731; the strain is separated from yak feces. Protease generated by the strain can decompose a complex protein composition into amino acid and peptide, the strain has good acid resistance and cholate resistance, the acid resistance is high, and the survival rate is 64 + / -4.06% after the strain is placed in artificial gastric juice with the pH value of 3.0 for 3 h; the strain can slowly grow in cholate with the concentration of 1.0%, and the growth efficiency reaches 11.36 + / -1.19% of that of cholate-free culture. The strain has high enzyme production capacity, and the activity is 198.5 U / mL. Protease secreted by the bacterium can help the host digest macromolecular protein in the feed.

This invention proposes a material for manufacturing polymer air fibers, its preparation method, and its applications, belonging to the field of home furnishing technology. The process involves preparing antibacterial TiO2 / ZnO / ZrO2 doped ceramic powder, depositing magnetic iron oxide (Fe3O4), modifying the surface with tannic acid, adding it to a water-soluble chitosan solution, immersing it in a melt-blown TPEE air fiber membrane, uniformly adding genipin solution, heating and reacting, removing the membrane, washing, and drying to obtain the material for manufacturing polymer air fibers. The TPEE air fiber membrane prepared by this invention has good mechanical properties. The modified ceramic powder is uniformly dispersed in the TPEE air fiber membrane, resulting in excellent antibacterial, environmentally friendly, immune-regulating, magnetic therapy, and far-infrared heating effects. This gives the resulting polymer air fiber material better comprehensive performance, making it a superior mattress support material with broad application prospects.

The invention belongs to the technical field of microorganisms, and particularly relates to serratia marcescens, a vaccine and a preparation method and application of the serratia marcescens. The preservation number of the serratia marcescens is CGMCC No.31403. Experiments prove that the serratia marcescens has high environmental stress tolerance and also has the biological effects of scavenging free radicals, regulating the immunity of the organism, resisting tumors and the like, so that the serratia marcescens has good practical application value.