Method for preparing high-purity coenzyme Q10 in large scale

A high-purity, coenzyme technology, applied in quinone separation/purification, organic chemistry, bulk chemical production, etc., can solve the problems of low yield and purity, pending research, high cost, etc., to achieve high product quality, reduce production costs, Effect of production cost reduction
CN102391092AActive Publication Date: 2012-03-28杭州华东医药集团康润制药有限公司
6 Cites 26 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
杭州华东医药集团康润制药有限公司
Publication Date
2012-03-28

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a method for preparing a separation coenzyme Q10, and in particular relates to a method for preparing a high-purity coenzyme Q10 in a large scale. The method comprises the following steps of: carrying out supercritical extraction on dry thallus containing the coenzyme Q10 to obtain extract liquor; and carrying out alkali treatment on the extract liquor to obtain a column loading liquid, carrying out column chromatography on the column loading liquid to obtain an eluent, concentrating the eluent, and crystallizing with ethanol to obtain the high-purity coenzyme Q10 with the purity higher than 99.5%. When the method provided by the invention is used for producing the coenzyme Q10, the overall yield is higher than 90%, and cost is low, thus the method provided by theinvention is applicable to industrial production.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a preparation method for separating coenzyme Q10, in particular to a large-scale preparation method for high-purity coenzyme Q10. Background technique

[0002] Coenzyme Q10, also known as vitamin Q, is the main component of proton transfer and electron transfer in the cellular respiratory chain in organisms. It has important physiological and pharmacological effects in the human body, so it is called vitamin Q or vitamin coenzyme Q10. It is in the respiratory chain. A coenzyme that does not bind tightly to proteins. In terms of medicine: it can treat heart disease, scurvy, high blood pressure, duodenal ulcer, gastric ulcer, necrotizing periodontitis, viral hepatitis; it also has anti-tumor, treatment of round alopecia and emphysema. function; it also has certain treatment for hearing impairment; it has a significant auxiliary treatment for AIDS and Parkinson's disease; it can be used in cosmetics and health products: it has an...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More