154 results about "Rickets" patented technology

The present invention relates to a method and transdermal pharmaceutical composition for preventing or reducing the likelihood of calcium deficiency or imbalances caused by calcium deficiency. The transdermal pharmaceutical composition includes a therapeutically effective amount of a pharmaceutically acceptable salt of calcium and a pharmaceutically acceptable carrier constituting a pluronic lecithin organogel. In addition to calcium, the transdermal pharmaceutical composition may also contain a therapeutically effective amount of: (1) a pharmaceutically acceptably salt of other minerals such as magnesium, zinc, selenium, manganese, or chromium; (2) a vitamin such as vitamin A, vitamin D, vitamin C, vitamin E or B-complex vitamins, choline, lecithin, inositol, PABA, biotin, or bioflavomoids; (3) a carotenoid such as lycopene or lutein; (4) a hormone such as dehydroepiandrosterone, progesterone, pregnenolone, or melatonin; (5) an amino acid such as arginine, glutamine, lysine, phenylalanine, tyrosine, GABA, tryptophan, carnitine, or acetyl-l-carnitine; (6) a fatty acid such as a fish oil or flax seed oil; (7) a vita-nutrient such as coenzyme Q10; (8) a cartilage building nutrient such as glucosamine, chondroitin, or MSM, (9) a herb such as ginkgo biloba, echinacea, 5-HTP, St. John's wort, or saw palmetto; or (9) any combination thereof. The transdermal pharmaceutical composition may be topically administered to a human to prevent or reduce the likelihood of calcium deficiency or imbalances caused by calcium deficiency such as hypertension, high cholesterol, colon and rectal cancer, osteomalacia, rickets, osteoporosis, cardiovascular disease, preeclampsia, tooth decay, and premenstrual syndrome.

The invention discloses a preparation method of an anti-oxidation and anti-pollution multi-nutrient block for dairy cows, belonging to the technical field of a block for the dairy cows. The method takes molasses, urea, vitamins and mineral elements as main raw materials; the anti-oxidation and anti-pollution multi-nutrient block is prepared by scientifically compounding natural antioxidant substances, Chinese herb extracts and seasoning extracts; the prepared multi-nutrient block for the dairy cows is moderate in hardness, dampproof, breakage-proof and high in weather fastness; the lapping surface of the block is low in bacterial content which is 1.5 per ten thousand of a comparison group; after the multi-nutrient block is used, the milk yield of the lactating dairy cows can be remarkably increased by 19.02%, the first estrus time is shortened by 13 days after parturition of the dairy cows, the conception rate of the dairy cows at the first estrus period is increased by 16.5% after parturition of the dairy cows, the oestrus proportion of the postpartum dairy cow group is increased by 18.4%, the feed intake and the immunity of the organism of the dairy cows can be effectively improved, the occurrence rates of nutritional diseases such as abnormal addiction disease, foot rot, white muscle disease, postpartum paralysis, rickets, mastitis, coarse fur and the like of the dairy cows can be remarkably reduced, and the occurrence rates are averagely reduced by 3.3-16.7%.

The invention discloses an anti-oxidization and anti-pollution compound nutritional block for dairy cattle and an application thereof, belonging to the technical field of blocks for the dairy cattle. The anti-oxidization and anti-pollution compound nutritional block takes molasses, urea, vitamins and mineral elements as main raw materials; a natural antioxidant substance, a traditional Chinese medicine extract and a condiment extract are scientifically compounded and the prepared compound nutritional block for the dairy cattle has moderate hardness, is moisture-proof and breakage-proof and has strong weather resistance; the content of infectious microbes of a lapping face of the block is low and is 0.015% of control group; the milk yield of milk secretion dairy cattle can be obviously improved by 19.02%; the first estrus time can be shortened for 13 days after delivery of the dairy cattle, the conception rate of the dairy cattle at a first estrus period after delivery is improved by 16.5% and the estrus rate of the dairy cattle crowd after delivery is 18.4%; the feed intake of the dairy cattle and the organism immunity of the dairy cattle can be improved effectively; the occurrence rates of nutritional diseases including dairy cattle allotriphagia, hoof rot, white muscle diseases, paralysis of the dairy cattle after delivery, rickets, mastitis, rough fur and feather and the like are reduced obviously and are averagely reduced by 3.3-16.7%.

The invention discloses a method for improving vitamin D content in a cordyceps sinensis calcium strengthening agent by ultraviolet irradiation, which comprises the following steps of: a, preparing a culture medium: preparing a liquid culture medium from a carbon source, a nitrogen source, mineral elements and the like, and sterilizing the prepared culture medium; b, inoculating cordyceps sinensis fungus into the culture medium, and performing shake culture to prepare liquid cordyceps sinensis fungus; c, inoculating the cordyceps sinensis fungus into the culture medium, performing the shake culture under certain conditions, and taking fermentation liquor out; and d, selecting a UV-B ultraviolet light source with the power of 14 to 60 W and the wavelength of 280 to 325 nm, pouring the cordyceps sinensis fungus fermentation liquor into a large culture dish, placing the ultraviolet light source over the culture dish, irradiating the prepared fermentation liquor, concentrating and drying the fermentation liquor, and breaking wall and grinding the obtained product into a powdery product. The method has the advantages of simple process, convenient operation and wide application to prevention and treatment of rickets of children, acalcerosis of women and osteoporosis of old peoples.

The invention discloses a method for improving vitamin D content in a lucid ganoderma calcium fortifier by ultraviolet irradiation. The method comprises the following steps of: a, preparing a culture medium, namely preparing a liquid culture medium from a carbon source, a nitrogen source, mineral elements and the like, and sterilizing and cooling the prepared culture medium; b, inoculating lucid ganoderma strains into the culture medium, and performing shaking culture under certain conditions so as to obtain liquid cordyceps sinensis strains; c, adding a certain amount of liquid lucid ganoderma strains into the culture medium, introducing gas, stirring for culture, and taking the fermentation liquor out; and d, selecting a UV-B ultraviolet light source with the power of 14 to 60W and the wavelength of 280 to 325nm, pouring the fermentation liquor of fungus lucid ganoderma into a large culture dish, putting the ultraviolet light source over the culture dish to irradiate the obtained fermentation liquor, concentrating and drying the irradiated fermentation liquor, and breaking walls and grinding into powdery products. The method for improving the vitamin D content has the advantages of simple process and convenient operation, and can be widely applied to the prevention and treatment of rickets in children, calcium deficiency in women and osteoporosis in old people.

The invention provides pet nutrient paste prepared through pandalus borealis processing by-products and a preparation method of the pet nutrient paste. Nutrient substances and flavor substances in pandalus borealis byproduct resources are sufficiently utilized, and besides, nutrition and functionality of the pet nutrient paste are improved. The product namely the pet nutrient paste has the characteristics of being natural in raw materials, comprehensive in nutrient functions and rich in flavor. The pet nutrient paste disclosed by the invention is rich in phosphatide and polyunsaturated fatty acids, so that cerebrum development of pets can be effectively promoted, the health of optic nerve can be protected, and the hair of the pets can be shiny. The pet nutrient paste can enhance immunity,protect skin health, strengthen vigor, and delay the ageing course of the pets; and besides, the pet nutrient paste contains rich calcium and chitin, so that the pet nutrient paste can prevent skeleton diseases of rickets, rhachitis, osteoporosis, postpartum paralysis and the like from occurring. The preparation course of the pet nutrient paste is easy to operate; and through a designed formula and an optimum technology, the finished product of the pet nutrient paste has favorable stability, and an oil-water separation phenomenon is not generated after the pet nutrient paste is stored for a long term.

A Chinese medicine for treating infantile rachitis is prepared from 14 Chinese-medicinal materials including astragalus root, pilose asiabell root, prepared rehmannia root, Chinese angelica root, etc. Its preparing process is also disclosed.

The invention relates to a drinking water containing asparaginic acid chelated calcium and in particular relates to an L-asparaginic acid chelated calcium drinking water, which comprises the following components: 1-5 parts of L-asparaginic acid chelated calcium, 150-700 parts of purified water, 0.5-1 part of licorice extractive, and 0.5-1 part of menthol. The L-asparaginic acid chelated calcium drinking water is suitable for various sub-health people who lack calcium and trace elements and is especially applicable to prevention and treatment of osteoporosis, children rickets, neuralgia and muscle twitching caused by calcium deficiency and the like, and also can be used by women in pregnancy and breast feeding and children for calcium supplementation.

The invention relates to the field of fruit processing and in particular relates to a beverage and a preparation method thereof. The preparation method comprises the following steps: adding collagen to coconut meat extracts and homogenizing to obtain the beverage which is advantageous in good stability, high protein content and complete nutrition. The beverage made by the method provided by the invention can improve health through diet and can achieve comprehensive effects of increasing bone mineral density, preventing and treating osteoporosis and rickets, improving yellowish and loose skin,and reducing wrinkles through diet.

The invention discloses a method for producing spicy meat chest with nutrient values. The raw materials in the percentage by weight of a prescription are as follows: lean meat of 80-88%, sugar of 6-8%, salts of 1-2%, a calcium element of 0.1-0.4%, a zinc element of 0.004-0.008%, an iron element of 0.003-0.006% and spicy powder seasonings of 0.03%-0.05%. During the processing time of the spicy meat chest, calcium citrate, zinc lactate, EDTA (Ethylene Diamine Tetraacetic Acid) Na-Iron micronutrient elements all of which are in accordance with the nutrition demands of a human body and have a high absorption rate are added to form a new nutrient meat chest. The spicy meat chest with nutrient values produced by the method disclosed by the invention is convenient to eat, economic in price and very good in mouth feeling; and if the meat chest is eaten for a long time, rickets of a child and osteoporosis of an audit caused by iron deficiency can be prevented; and the spicy meat chest with nutrient values also can prevent bradygenesis of the child, hypophrenia and sexual organ mal-development caused by zinc deficiency, and avoid functional disorder of an organism of a human body and other diseases.

The invention relates to a microorganism multienzyme additive for promoting the growth and development of pets, which is characterized in that beneficial strains that are fixedly planted in healthy animal intestinal tract are filtered by microwave and radial-induced technology by adopting co-induction; methods of liquid complex culture and solid amplification culture are adopted, and special enzyme inducer and protein source are added, thereby causing the beneficial strains to amount to 3 billion/g and contain large quantity of physiological metabolites, such as organized eozymes, small peptides, antioxidants, free amino acid, vitamin, etc. The microorganism multienzyme additive of the invention facilitates the pets to be more glossy, massively built, more immune competent and protected from enteric diseases, such as diarrhea, constipation, acute and chronic enteritis, etc., rickets, osteoporosis, etc. Meanwhile, the pollution caused by the excrement of livestock and poultry is relieved; as being free of antibiotic or steroid hormone, the microorganism multienzyme additive is an environmental friendly, safe and novel product of breed technology.

The invention discloses a method for making calcium-zinc nutrition health dumplings. The method mainly comprises burdening and preparation methods of stuffing and dumpling wrappers. The stuffing is prepared from fresh pork, edible oil, shallot, fresh ginger, garlic, pepper, aginomoto, soybean sauce, fresh vegetables and drinking water as raw materials. The dumpling wrappers are prepared from the raw materials of wheat flour powder, drinking water, a calcium gluconate solution and a zinc gluconate solution. The nutrition health dumplings made by the method not only has nutrients of common dumplings and provides human nutrition, but also can replenish trace elements, calcium and zinc, necessary for a human body. Chondropathy, slow teething, sparse teeth, small body, rickets and the like caused by calcium deficiency are reduced, and growth retardation, hypophrenia, mental fatigue, anorexia and the like of the human body caused by zinc deficiency are reduced.

The invention discloses a flavor jam and a producing method thereof, wherein the flavor jam is composed of the following raw materials: 20-22 of actinidia chinensis, 6-8 of apple, 10-15 of cherry tomato, 8-10 of dried snow pear, 13-15 of a low-fat milk powder, 7-8 of chicken bone meal, 3-5 of highland barley flour, 3-4 of star anise, 2-4 of angelica dahurica, 2-4 of gynostemma pentaphylla, 5-7 of liquorice, 1-2 of semen hoveniae, 5-6 of radix puerariae, 2-4 of radix bupleuri, 7-8 of herba lophatheri, 0.4-0.5 of an echinacea purpurea extract, 30-35 of white granulated sugar, 5-7 of high fructose syrup, 8-10 of xanthan gum, 4-5 of palm oil, and a proper amount of water. The fresh actinidia chinensis, apple and cherry tomato are processed into the jam, and the nutrition is extremely rich; infants and young children can be supplemented with calcium and phosphorus through eating the apple, rickets is prevented, and an assisting curative effect is provided for iron deficiency anemia; and various Chinese herbal medicines are also added in the formula, so that the jam has the efficacies of nourishing yin, moistening lung, tonifying spleen, invigorating qi, enhancing human body immunity and the like.

The invention relates to a composition which can be used in the treatment and/or prevention of osteoporosis or rickets, comprises calcium amino acid, soybean isoflavones and selected vitamin and microelement, wherein the weight ratio of calcium amino acid and soybean isoflavone is 1-1000 : 1-120.

The invention relates to nutrient balanced health blend oil and a preparation method thereof. The invention relates to the field of edible oil, and discloses the nutrient balanced health blend oil and the preparation method thereof. The nutrient balanced health blend oil is composed of extra virgin coconut oil, extra virgin peony seeds oil, extra virgin acer truncatum seeds oil, extra virgin walnut oil, extra virgin tea oil, extra virgin peanut oil, extra virgin sunflower oil, extra virgin olive oil, and an acer truncatum emulsion. The nutrition proportion of saturated fatty acid content to monounsaturated fatty acid to polyunsaturated fatty acid in the nutrient balanced health blend oil is 1:1:1, a ratio of n-6 to n-3 in unsaturated fatty acid is 5.49:1; the blend oil accords with nutrition balance proportion recommended by World Health Organization and nutrition institute, the blend oil also contains abundant vitamin E and nervonic acid; long-term eating of the nutrient balanced health blend oil can promote blood circulation, prevent cardio cerebrovascular disease, improves function of digestive system, increases function of endocrine system; the blend oil has effects for protecting skin, resisting cancer, and preventing radiation, has functions of antisenescence, prevention of children rickets and adult osteoporosis, can improve memory, and can delay brain function decline and increases immunization capability of human body.

The invention discloses health milk, which comprises the following components: 78 to 95 percent of milk, 2 to 13 percent of yam powder, 1 to 5 percent of almond powder, and 0.5 to 4 percent of food additives, wherein the food additives are a flavoring essence, gellan gum, microcrystalline cellulose, sodium alga acid, sucrose fatty acid esters, sodium hexametaphosphate, disodium hydrogen phosphate, nisin, sucralose and glycerol monostearate. The components are stirred, disinfected and packaged. The health milk has the advantages of low loss of nutrients, minerals and vitamins, and capacity of being absorbed easily. The milk contains all nutrients required by a human body, contains L-tryptophan, and has calming and hypnotic effects; yam contains dioscin (soluble in ethanol), amylase, phlegm and various vitamins; and almond contains flavonoid, polyphenols, an active ingredient of amarogentin, and other nutrients, and has effects of eliminating phlegm, promoting digestion, treating liver, lung and kidney wind deficiency, reducing fat, complementing calcium, preventing and treating lumbocrural pain and rickets in children, strengthening muscles and bones, resisting tumors and the like.

The invention discloses a composite medicament for treating infantile stomach heat rickets, which consists of two medicinal compositions. The medicinal composition I is prepared from the following raw materials in part by weight: 10 to 30 parts of gypsum and 15 to 45 parts of Codonopsis pilosula. The medicinal composition II is prepared from the following raw materials in part by weight: 80 to 120 parts of Codonopsis pilosula, 80 to 120 parts of astragalus root, 80 to 120 parts of rehmanniae vaporata, 80 to 120 parts of large head atractylodes rhizome, 80 to 120 parts of yam, 80 to 120 parts of medicated leaven, 80 to 120 parts of malt, 40 to 60 parts of keel, 40 to 60 parts of oyster and 40 to 60 parts of Chinese date. The composite medicament for treating infantile stomach heat rickets overcomes the drawbacks of the conventional methods for treating nfantile stomach heat rickets and has a remarkable treatment effect, high cure rate and no adverse reaction.

The invention discloses a Chinese medicinal preparation for treating rickets and osteoporosis and a preparation method thereof. The preparation is characterized by comprising the following components in part by weight: mothers of pearls, oysters and pearls. The preparation method comprises the following steps of: cleaning, namely after removing stratum corneums from the mothers of pearls and the oysters, cleaning and drying the mothers of pearls and the oysters, and cleaning and drying the pearls; crushing, namely crushing the mothers of pearls, the oysters and the pearls respectively until the particles of which the particle size is more than 30 mum are less than 10 percent; drying, sterilizing and activating, namely sterilizing the three kinds of powder for more than 60 minutes at the temperature of 120 DEG C in a dry and hot sterilizing cabinet respectively, and activating the three kinds of powder under the magnetization intensity of more than or equal to 5,000 gauss in a magnetizer respectively; mixing, namely preparing the three kinds of powder according to proportion of a formula, mixing the pearl powder and the oyster powder for 5 minutes, and adding the pearl powder for three times, wherein the adding amount for each time is one third of the formula amount, and the mixing time for each time is 5 minutes; and forming the preparation, namely forming the mixed powder in the step D according to requirements.

The present invention relates generally to 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimid-4-yl}-1-methyl-urea or a pharmaceutically acceptable salt or solvate thereof or a pharmaceutical composition comprising 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimid-4-yl)-1-methyl-urea or a pharmaceutically acceptable salt or solvate thereof for use in the treatment of X-linked hypophosphatemic rickets (XLH), autosomal dominant hypophosphatemia rickets (ADHR), autosomal recessive hypophosphatemic rickets (ARHR), tumor-induced osteomalacia, post-renal transplant hypophosphatemia, epidermal nevus syndrome, osteoglophonic dysplasia or McCune-Albright syndrome.

The present invention relates to calcifediol soft capsules, to their use in the treatment or prevention of diseases related to vitamin D deficiency, such as vitamin D deficiency, demineralization such as hypocalcemia and hypophosphatemia, renal osteodystrophy, rickets, osteoporosis, osteopenia, osteoarthritis, osteoarthrosis, osteomalacia, hypoparathyroidism, and inflammatory bowel disease, and to their process of manufacture.

The present invention discloses one kind of Chinese medicine composition, and the Chinese medicine composition is prepared with oyster, Dangshen, ophiopogon root, white atractylodes rhizome, date and other Chinese medicinal materials. The Chinese medicine composition is used clinically in treating children's rachitis and other calcium deficiency caused diseases. The present invention also discloses the preparation process of the Chinese medicine composition.

Belonging to the technical field of medicine application, the invention discloses pharmaceutical application of caffeic acid 3, 4-dihydroxyl phenethylester. A prevention and/or treatment medicine prepared from the caffeic acid 3, 4-dihydroxyl phenethylester (CADPE) can be used for inhibiting osteoclast differentiation, inhibiting an osteoclast bone erosion function, promoting osteoblast differentiation, and promoting an osteoblast bone formation function. The medicine can be used for preventing and/or treating osteoclast activity abnormality caused diseases, which include osteoporosis, rheumatoid arthritis, periodontitis, tooth loss, Paget's disease, rickets, osteoclastoma, myeloma bone disease and cancer bone metastasis caused bone destruction, etc.