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111 results about "Astragalus Root" patented technology

Exosome-like nano-vesicles derived from plant radix astragali and preparation method and application of exosome-like nano-vesicles

The invention relates to a plant astragalus membranaceus-derived exosome-like nano-vesicle as well as a preparation method and application thereof. The nano-vesicle is prepared by chopping astragalus membranaceus roots, juicing, carrying out differential-ultra-high-speed centrifugation and filtering. The nano vesicle disclosed by the invention has good biocompatibility and immunomodulatory activity, can be used for intervening bronchial asthma, and shows a relatively good treatment effect; the nano-vesicle can be used as a novel natural plant-derived drug delivery system, and the problems of poor stability, single action mechanism, low delivery efficiency and the like of traditional Chinese medicine components are solved.
Owner:SHANGHAI TONGJI HOSPITAL

Angelica sinensis and paeonia lactiflora blood activating capsule

The invention provides an angelica sinensis and radix paeoniae alba blood-activating capsule, which belongs to the technical field of traditional Chinese medicine pharmacy and is prepared from the following traditional Chinese medicinal materials: angelica sinensis, radix paeoniae alba, astragalus membranaceus, deer-horn glue, fructus lycii, teasel root, cassia twig, peach kernel, centipede, dragon's blood, ground beetle, native copper (calcined), mustard seed and radix achyranthis bidentatae. Angelica sinensis and radix paeoniae alba nourish and activate blood as a core and cooperate with astragalus membranaceus to tonify qi, and qi circulation causes smooth blood circulation, so that the qi-blood running state of an organism can be effectively improved; the deer-horn glue, the fructus lycii and the radix dipsaci nourish and nourish the liver and the kidney, can enhance the self-repairing and nourishing capacity of the body and assist in strengthening muscles and bones; the cassia twig can warm and dredge meridians, and can dissipate blood stasis in the body, promote local blood circulation and relieve pain and swelling by matching with the peach kernel, the dragon's blood, the ground beetle and the native copper (calcined); the centipede is good in dredging collaterals, can go deep into meridians and collaterals and The mustard has the effects of warming lung, eliminating phlegm, benefiting qi and regulating qi activity; the radix achyranthis bidentatae removes blood stasis, stimulates the menstrual flow and leads the medicine to move downwards to directly reach the disease site, and the effects of promoting blood circulation to remove meridian obstruction, tonifying liver and kidney and strengthening tendons and bones are achieved through cooperation of multiple groups of medicinal materials.
Owner:HEILONGJIANG LINBAO PHARM CO LTD

Microbial agent containing bacillus velezensis and application of microbial agent to astragalus membranaceus

The invention belongs to the technical field of microbial agents, and particularly relates to a microbial agent containing bacillus velezensis and application of the microbial agent to astragalus membranaceus. The invention discloses a microbial agent for astragalus membranaceus. The microbial agent is prepared by mixing bacillus velezensis powder, bacillus subtilis powder and bacillus pumilus powder according to the mass ratio of 1: (1-10): (1-5), the bacterium content of the bacillus velezensis powder, the bacillus subtilis powder and the bacillus pumilus powder is 0.2-0.5 billion cfu / g. The bacillus velezensis, the bacillus subtilis and the bacillus pumilus are fermented respectively, fermentation liquor is taken to be prepared into powder, and the powder is mixed according to a certain mass ratio to form the compound microbial agent, so that the compound microbial agent can improve the prevention and treatment effect on the radix astragali root knot nematode disease, is green and environment-friendly, can effectively overcome the defects of chemical agents, and has a good application prospect. Support is provided for biological prevention and control of the radix astragali root knot nematode disease, and meanwhile healthy growth of radix astragali plants can be guaranteed.
Owner:BEIJING GOLDENWAY BIO TECH

Preparation method of high-purity astragalus polysaccharide raw material powder and product thereof

The invention relates to the technical field of extraction and purification of natural medicines, and discloses a preparation method of high-purity astragalus polysaccharide raw material powder, which comprises the following steps: hot water extraction: extracting astragalus root powder of 80-120 meshes for 2-3 times at 80-90 DEG C for 1.5-2.0 hours each time according to a solid-to-liquid ratio of (1: 10)-(1: 30), merging filtrates, and concentrating under reduced pressure until the volume is 1 / 3-1 / 5 of the original volume; deproteinizing and decoloring: adding neutral protease to act for 1-4 hours at the temperature of 45-55 DEG C and the pH value of 6.5-7.5, and inactivating at the temperature of 90 DEG C for 10 minutes; adding 0.5%-2.0% of cross-linked polyvinylpyrrolidone, performing contact for 10-20 minutes, and performing solid-liquid separation to obtain clear liquid; and two-phase distribution and post-treatment: adding polyethylene glycol 4000 and sodium dihydrogen phosphate / disodium hydrogen phosphate into the clear liquid. The invention aims to shorten the process, improve the yield and purity and reduce protein / polyphenol and salt / polymer residues under the condition of not using ion exchange resin.
Owner:SHANXI UNIV

MOTS-c targeted delivery system based on astragalus-derived exosome and application of MOTS-c targeted delivery system in myocardial ischemia-reperfusion injury

The invention relates to an MOTS-c targeted delivery system based on an exosome derived from astragalus membranaceus and application of the MOTS-c targeted delivery system in myocardial ischemia-reperfusion injury. The preparation method comprises the following steps: preparing an exosome AExo from radix astragali from fresh radix astragali as a raw material, modifying a cardiac troponin I targeting peptide LPFFD to the surface of the AExo by using an EDC / NHS chemical cross-linking method to obtain LPFFD-AExo, and loading a mitochondrial derived small peptide MOTS-c into the LPFFD-AExo by using an ultrasonic-assisted penetration method to obtain the LPFFD-AExo-MOTS-c. According to the invention, the accurate delivery efficiency of the damaged myocardial tissue can be improved, and efficient and accurate delivery of MOTS-c to the ischemia reperfusion damaged myocardial tissue is realized, so that the ferroptosis inhibition capability of MOTS-c is obviously enhanced, the myocardial protection effect on MI / R injury is improved, and finally efficient targeted therapy on MI / R injury is realized.
Owner:李小佩 +2

Astragalus mongholicus calycosin methyltransferase protein AmOMT1, coding gene, primer group and application of astragalus mongholicus calycosin methyltransferase protein AmOMT1

The invention provides an astragalus membranaceus calycosin-7-methyltransferase protein AmOMT1, a coding gene, a primer group and application of the astragalus membranaceus calycosin-7-methyltransferase protein AmOMT1, and belongs to the technical field of biology. The amino acid sequence of the astragalus membranaceus calycosin-7-methyltransferase protein AmOMT1 is as shown in SEQ ID No. 1 (sequence identifier number 1). According to the present invention, based on the radix astragali seu hedysari genome and the second-generation transcriptome data, the transmethylase AmOMT1 having 4 'and 7-site methylation functions on 3', 4 ', 7-trihydroxy isoflavone simultaneously is found and identified by using the reverse genetics method, and the experiment results show that the AmOMT1 can catalyze the methylation of the 3', 4 ', 7-trihydroxy isoflavone to generate calycosin and 3', 4 '-dihydroxy-7-isoflavone, and the transmethylase AmOMT1 can catalyze the methylation of the 3', 4 ', 7-trihydroxy isoflavone can catalyze the methylation of the 3', 4 ', 7-trihydroxy isoflavone to generate the 3', 4 '-dihydroxy-7-isoflavone.
Owner:INSTITUTE OF CHINESE MATERIA MEDICA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES

A method for detecting chemical components in a traditional Chinese medicine composition

The application provides a detection method of chemical components in a traditional Chinese medicine composition. The detection method is combined with liquid chromatography and mass spectrometry, and is used for qualitative detection of chemical components in a traditional Chinese medicine composition prepared from red peony root, astragalus root, rehmannia root, safflower, female privet fruit, eclipta, rhubarb, panax notoginseng, giant worm, ginkgo leaf, cassia seed and paeonia suffruticosa. 82 kinds of chemical components are detected and confirmed from the traditional Chinese medicine composition, so that the detection method can be used as a discrimination method for quality control of the traditional Chinese medicine composition, and can provide analysis technical support for mechanism research and effective component research of the traditional Chinese medicine composition.
Owner:HEBEI YILING MEDICINE INST

Traditional Chinese medicine compound composition for improving facial chloasma as well as preparation method and application of traditional Chinese medicine compound composition

The invention discloses a traditional Chinese medicine compound composition for improving facial chloasma as well as a preparation method and application of the traditional Chinese medicine compound composition. The composition is prepared from radix rehmanniae praeparata, astragalus membranaceus, poria cocos, peach kernels, mulberries, ginseng, jujubes, red roses with double petals, radix angelicae and cinnamon through compatibility, and the red roses with double petals and mulberries are innovatively and synergistically compatible and are combined with traditional qi-reinforcing and blood-nourishing medicines to generate synergistic interaction. According to the invention, a perfect quality control system is established, and a multi-index content determination dual control method is adopted. Clinical tests show that the total effective rate of the traditional Chinese medicine composition for treating qi-blood deficiency and blood stasis type chloasma reaches 92.5%, and the traditional Chinese medicine composition has the outstanding advantages of multi-target effect, high safety, low recurrence rate and the like. The invention further provides a standardized preparation process which is suitable for industrial production and has a wide application prospect in the fields of medicines, cosmetics and health foods.
Owner:JIANKANGYUAN PHARMA GRP IND CO LTD

Traditional Chinese and western medicine combined therapy for treating amyotrophic lateral sclerosis patient

The traditional Chinese medicine comprises (1) radix puerariae, (2) radix angelicae sinensis, (3) radix salviae miltiorrhizae, (4) radix codonopsis, (5) radix astragali, (6) fructus perillae, (7) fructus ziziphi jujubae, (8) radix bupleuri, (9) radix scutellariae, (10) flos carthami, (11) radix curcumae, (12) radix et rhizoma rhei, (13) pericarpium zanthoxyli, (14) radix glycyrrhizae, (15) radix ophiopogonis, (16) fructus schizandrae, (17) radix aconiti carmichaeli, (18) radix ginseng, (19) poria cocos, (20) gypsum, (21) oyster, (22) cassia twig and (23) semen plantaginis. Or extracts of the above components, the amount of the extracts being equivalent to the amount of the raw materials of the corresponding components. The invention aims at the clinical curative effect of amyotrophic lateral sclerosis diseases with different pathological manifestations. The medicine can be combined with western medicines for use.
Owner:XIEFENG MOLECULAR MEDICAL CO LTD

Cream formula based on qi and blood tonifying and heart and kidney dredging and regulating and preparation method

The invention relates to an ointment formula based on qi and blood tonifying and heart and kidney dredging and regulating and a preparation method, and belongs to the technical field of traditional Chinese medicine, the ointment is prepared from ginseng, astragalus membranaceus, five-prepared rehmannia glutinosa, Chinese yam, poria cocos, deer-horn glue, tortoise plastron, donkey-hide gelatin, dogwood, fructus lycii, semen cuscutae and other medicinal materials according to a specific ratio. The preparation method comprises the following steps: grinding part of the medicinal materials into powder, decocting the prepared rhizome of rehmannia firstly, decocting a plurality of sub-medicinal materials together, melting the glue medicinal materials by heat, mixing with other medicinal material decoctions, and concentrating to obtain the ointment. Through the synergistic effect of the medicinal materials, the comprehensive effects of reinforcing qi and nourishing yin, warming yang and promoting diuresis, tonifying kidney and replenishing essence and promoting circulation of heart and kidney are achieved, and the traditional Chinese medicine composition has the advantages of being comprehensive in curative effect, small in side effect and sufficient in component retention for consumptive disease, premature senility, chronic heart failure and arrhythmia caused by deficiency of qi and blood, yang deficiency and water flooding and heart and kidney disharmony.
Owner:孙玉彰

Automatic milkvetch root rubbing device and milkvetch root rubbing method

The invention provides an automatic milkvetch root rubbing device, and relates to the technical field of traditional Chinese medicinal material processing, the automatic milkvetch root rubbing device is characterized in that a first guide rail is arranged on a frame mechanism, and second guide rails are arranged on two sides of the first guide rail in parallel; the clamp mechanism is used for clamping an astragalus membranaceus bundle, is arranged on the first guide rail, can slide along the first guide rail and conveys the clamped astragalus membranaceus bundle to the rubbing working area; the rubbing mechanism comprises two sets of rubbing assemblies arranged on the two sides of the first guide rail and an upper rubbing plate lifting assembly; a lower rubbing plate of the rubbing assembly is arranged on a second guide rail in a sliding mode, an upper rubbing plate is arranged above the lower rubbing plate, the upper end of the upper rubbing plate is connected with an upper rubbing plate lifting assembly, and the upper rubbing plate lifting assembly can lift the upper rubbing plate to move in the vertical direction; the driving end of the first driving unit is connected with the lower rubbing plate and can drive the lower rubbing plate to reciprocate on the corresponding second guide rail. According to the scheme, labor force can be liberated, the kneading processing efficiency and the kneading uniformity are improved, and then the radix astragali processing quality is improved.
Owner:NINGXIA UNIVERSITY

Five treasures pill prepared from five Chinese medicinal ingredients of astragalus root, rhizoma polygonati, prepared rehmannia root, poria and dried tangerine or orange peel and its preparation method

PendingCN122351381AFormularyDisease
This invention relates to a Five Elements Pill composed of five traditional Chinese medicines: Astragalus membranaceus, Polygonatum sibiricum, Rehmannia glutinosa, Poria cocos, and Citrus reticulata peel, and its preparation method. In this Five Elements Pill, Astragalus membranaceus is the principal ingredient, Polygonatum sibiricum and Rehmannia glutinosa are the assistant ingredients, Poria cocos is the adjuvant ingredient, and Citrus reticulata peel is the guiding ingredient. This invention, based on the principles of the Five Elements theory and the philosophy of syndrome differentiation and treatment, carefully selects and combines these five traditional Chinese medicines. The formula is precise and rational, with significant therapeutic effects, suitable for medicinal and health maintenance use by middle-aged and elderly people, and can meet their needs for disease prevention, chronic diseases, and geriatric diseases. This invention combines modern and traditional methods, making it practically applicable and producing high-quality, qualified products that meet social needs.
Owner:郜海晶

A traditional Chinese medicine composition for preventing and treating pig bacterial pneumonia, a preparation method and application thereof

The application discloses a traditional Chinese medicine composition for preventing and treating pig bacterial pneumonia and a preparation method and application thereof. The traditional Chinese medicine composition comprises the following components: Ephedra, apricot kernel, gypsum, Astragalus root, Anemarrhena asphodeloides, Cape jasmine fruit, talc, licorice, honeysuckle, forsythia, rhubarb, mirabilite, peony root and kudzurpini radix. The application studies and clinically applies traditional Chinese medicine by combining traditional preparation technology with modern preparation technology, and adopts the traditional Chinese medicine compound prepared through fermentation to prevent and treat pig bacterial pneumonia, so as to solve the above problems. Through clinical application, the traditional Chinese medicine compound has a treatment effect on pig bacterial pneumonia, and the cure rate can reach 91.83%, and the cure rate can reach 95.97% after fermentation, the drug efficacy is improved, the recurrence is difficult, and there is no drug residue. In addition, the components are common traditional Chinese medicines, the cost is low, the safety is high, and there is no side effect. The application not only reduces the economic loss of breeders, but also meets the demand of people for green food, and conforms to the development trend.
Owner:SICHUAN AGRI UNIV

Bifidobacterium longum probiotics combined with qi-yang-blood nourishing food-medicine homologous composition, preparation method and application in regulating immunity, inhibiting tumor cell proliferation and reducing tumor-induced inflammation

ActiveCN120381492BBacteriaAntipyreticBiotechnologyCitrus medica
Disclosed in the application are a Bifidobacterium longum probiotic combined with a qi-tonifying and blood-nourishing medicinal and edible homologous composition, a preparation method thereof and application thereof in regulating immunity, inhibiting tumor cell proliferation and reducing tumor-induced inflammation, including Bifidobacterium longum subsp. infantis NKU FB3-14 and the qi-tonifying and blood-nourishing medicinal and edible homologous composition; the qi-tonifying and blood-nourishing medicinal and edible homologous composition comprises, by weight, 5-30 parts of ginseng, 5-20 parts of longan arillus, 20-50 parts of astragalus root, 10-50 parts of polygonatum, 5-20 parts of poria cocos, 5-15 parts of mulberry, 5-20 parts of licorice, 10-30 parts of orange peel, 5-15 parts of citrus medica, 5-20 parts of double-petaled rose flower and 3-10 parts of hawthorn. The probiotic preparation and the medicinal and edible homologous material have a synergistic effect, and the ability to inhibit the proliferation level of liver tumor cells H22 in vitro is determined.
Owner:TIANTIANNENG HEALTH IND GRP CO LTD +1

Traditional Chinese medicine composition for preventing and treating cerebral arterial thrombosis and preparation method thereof

The invention belongs to the technical field of Chinese herbal medicines, and particularly relates to a traditional Chinese medicine composition for preventing and treating cerebral arterial thrombosis and a preparation method thereof. The traditional Chinese medicine composition comprises leeches, earthworms, miscanthus, pseudo-ginseng, astragalus membranaceus, poria cocos, almonds, peach kernels, angelica sinensis, immature bitter orange, radix polygoni multiflori preparata, pericarpium citri reticulatae, carthamus tinctorius, liquorice and borneol flakes. By combining the traditional Chinese medicines, the traditional Chinese medicine composition has a remarkable treatment effect on preventing and treating cerebral arterial thrombosis. In addition, the traditional Chinese medicine composition disclosed by the invention is high in safety and definite in curative effect, and has a wide application prospect in the field of prevention and treatment of cerebral arterial thrombosis.
Owner:BEIJING SUNSHINE FOUNDATION PHARMACEUTICAL TECHNOLOGY CO LTD

Astragalus root calyx heterophylla methyltransferase protein AmOMT1, coding gene, primer set and application thereof

The application provides a astragalus membranaceus calyx heterophylla isoflavone methyltransferase protein AmOMT1, a coding gene, a primer set and application thereof, and belongs to the technical field of biotechnology.The amino acid sequence of the astragalus membranaceus calyx heterophylla isoflavone methyltransferase protein AmOMT1 is shown as SEQ ID No.1.Based on astragalus membranaceus genomic and second-generation transcriptomic data, a methyltransferase AmOMT1 with 4' and 7 position methylation functions for 3', 4', 7-trihydroxyisoflavone is found and identified by a reverse genetics method.Experiments show that AmOMT1 can catalyze the methylation of 3', 4', 7-trihydroxyisoflavone to generate calyx heterophylla isoflavone and 3', 4'-dihydroxy-7-methoxyisoflavone.
Owner:INSTITUTE OF CHINESE MATERIA MEDICA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES

Pharmaceutical composition for treating rheumatoid arthritis as well as preparation method, traditional Chinese medicine preparation and application thereof

The invention discloses a pharmaceutical composition for treating rheumatoid arthritis as well as a preparation method, a traditional Chinese medicine preparation and application thereof, and belongs to the technical field of pharmaceutical compositions. The technical problem to be solved is to provide a preparation method of a pharmaceutical composition with higher drug utilization rate aiming at the current situation that a heat-clearing and blood-activating formula in the prior art is high in active ingredient loss and low in drug utilization rate. The key point of the technical scheme is that the preparation method of the pharmaceutical composition comprises the following steps: (1) mixing rhizoma smilacis glabrae, rhizoma atractylodis stir-fried with bran, rhizoma dioscoreae septemlobae and caulis sinomenii, adding water, soaking, performing enzyme extraction, performing solid-liquid separation, and concentrating enzymatic hydrolysate to obtain enzymatic hydrolysate; (2) mixing honeysuckle, cortex phellodendri and radix paeoniae rubra, performing alcohol extraction, performing solid-liquid separation, combining filtrate, and concentrating an alcohol extract to obtain an alcohol extract; (3) mixing the vinegar-processed curcuma zedoary, salvia miltiorrhiza and astragalus membranaceus with water, performing water extraction, performing solid-liquid separation, combining filtrate, and concentrating a water extracting solution to obtain a water extract; and (4) mixing the enzymolysis paste, the alcohol extraction extract and the water extraction extract, and drying.
Owner:SHAANXI PANLONG PHARMACEUTICAL GROUP LIMITED BY SHARE LTD

Traditional Chinese medicine composition for treating vital energy deficiency syndrome

The invention relates to a traditional Chinese medicine composition for treating deficiency of primordial qi, which is prepared from the following raw material medicines by weight: ginseng, astragalus membranaceus, angelica sinensis, prepared rehmannia root, Chinese yam, pulp of dogwood fruit, eucommia ulmoides, medlar and honey-fried licorice root, and the raw material medicines are prepared into required dosage forms as required. The traditional Chinese medicine composition is rich in raw materials, scientific and reasonable in formula and simple in preparation method, has the effects of reinforcing vital energy, tonifying qi, lifting yang, tonifying spleen, tonifying kidney and consolidating essence and qi, is effectively used for treating vital energy disease-vital energy deficiency syndrome, is good in curative effect and safe in medication, is an innovation of the medicine for treating vital energy disease-vital energy deficiency syndrome, and has wide application prospects, and the formula is compatible according to the main and secondary relationship of monarch, minister, assistant and guide. The practical clinical popularization and application value is realized.
Owner:HENAN PROVINCE HOSPITAL OF TCM THE SECOND AFFILIATED HOSPITAL OF HENAN UNIV OF TCM

Formula and preparation process of long-period biological food for improving function regeneration of human body

The invention discloses a long-period biological food formula for improving human body function regeneration and a preparation technology, and relates to the technical field of healthy food. The formula is composed of core raw materials and auxiliary raw materials, the core raw materials comprise pine trees, ginseng, pinenut kernels and crocodiles, the auxiliary raw materials comprise radix astragali, fructus lycii, radix angelicae sinensis, rhizoma dioscoreae, kelp, cordyceps militaris and poria cocos, all the raw materials are proportioned according to specific parts by weight, and long-period organisms are selected to enrich sufficient active ingredients. The preparation process sequentially comprises the following steps: pretreating the raw materials, extracting effective components, mixing and forming, performing sterile packaging, and retaining the activity of the components by adopting the technologies of low-temperature freeze-drying, ultrasonic-assisted water extraction, supercritical CO2 extraction and the like. Through the synergistic effect of active ingredients of multiple raw materials, the health food can enhance human immunity, improve microcirculation and improve cell regeneration capacity, is high in product safety and convenient to eat, can be directly added into daily staple food, improves human vitality from the source, and meets the requirements of people for health and longevity.
Owner:韩文江

Ginseng and astragalus membranaceus Kangpu tea as well as preparation and application thereof

The invention relates to the technical field of health-preserving drinks, in particular to ginseng and astragalus membranaceus Kangpu tea as well as preparation and application of the ginseng and astragalus membranaceus Kangpu tea. The preparation method comprises the following steps: firstly, uniformly mixing ginseng powder, astragalus membranaceus powder, white granulated sugar and water, and then sterilizing to obtain a raw material mixed solution; then, activated kombucha is added into the raw material mixed liquid, fermentation treatment is conducted, and fermentation liquid is obtained; finally, the fermentation liquor is subjected to centrifugal treatment, supernate is collected, and the ginseng and astragalus membranaceus kangpu tea is obtained. The prepared functional health drink has excellent antioxidant activity, various functions and nutritional values and rich flavor, and can meet multiple requirements of consumers on functional health drinks.
Owner:SHANGHAI INST OF TECH

A total ginsenoside-salvia miltiorrhiza total phenolic acid cardiac function improving composition

The application discloses a ginseng and astragalus root-danshen total phenolic acid heart function improving composition, and relates to the technical field of medicines.The active ingredients of the composition are composed of three chemical monomers of ginsenoside Rg1, astragaloside B and danshensu, and the weight ratio is 1:0.5 to 1:2 to 3.Through combination of the three specific monomers in the accurate proportion, multiple key nodes of myocardial cell energy metabolism can be synergistically regulated, and myocardial energy metabolism disorder under heart failure state can be systematically intervened.The composition has clear components, controllable quality, and can be prepared into various dosage forms such as tablets and capsules.Compared with medicinal material extracts with complex components, the composition provided by the application has the advantages of clear action mechanism, accurate proportion, stable quality and the like, and provides a new drug selection for the treatment of heart failure.
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE

Traditional Chinese medicine composition with effects of soothing nerves and helping sleep as well as preparation method and application of traditional Chinese medicine composition

PendingCN121197326AOrganic active ingredientsNervous disorderBiotechnologyPLATYCLADUS ORIENTALIS SEED
The invention belongs to the field of biological medicine, and particularly relates to a traditional Chinese medicine composition with nerve soothing and sleep aiding effects, a preparation method and application, the composition is prepared by compounding spina date seed, platycladi seed, astragalus membranaceus, longan aril, medlar, dogwood, tuber fleeceflower stem, bighead atractylodes rhizome, angelica sinensis, poria cocos, polygala tenuifolia, ginseng, lily, elecampane, pericarpium citri reticulatae, liquorice, wheat and gamma-aminobutyric acid. The preparation method comprises the following steps: S1, drying and crushing semen ziziphi spinosae, semen boitae, rhizoma atractylodis macrocephalae, radix angelicae sinensis, radix aucklandiae and pericarpium citri reticulatae, and performing supercritical carbon dioxide extraction to obtain a raw material volatile oil A; s2, crushing astragalus membranaceus, longan aril, wolfberry, dogwood, tuber fleeceflower stem, poria cocos, polygala tenuifolia, ginseng, lily, liquorice and wheat, mixing the crushed materials with medicine residues obtained after the volatile oil is extracted in the step S1, and performing extraction, concentration and drying to obtain raw material powder B; s3, clathrating the volatile oil A obtained in the step S1 with hydroxypropyl beta cyclodextrin, and drying to obtain raw material powder C; s4, mixing the raw material powder B, the raw material powder C and gamma-aminobutyric acid to obtain the traditional Chinese medicine composition. The composition and the preparation thereof can improve the symptoms of lassitude, impatient temperament and irritability caused by difficulty in falling asleep, dreaminess, easy waking and insufficient sleep of an insomnia patient, and can deepen the sleep depth of the patient and prolong the sleep duration.
Owner:HANGZHOU HEYON PHARM TECH CO LTD

Pharmaceutical composition for preventing birth defects and improving memory

The invention discloses a pharmaceutical composition for preventing birth defects and improving memory, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, vitamin complex B, vitamin C, vitamin D, vitamin E, vitamin k, macroelements including calcium, phosphorus, potassium and magnesium and microelements including zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese, traditional Chinese medicines including glossy privet fruit, astragalus membranaceus, fructus lycii, semen cuscutae and nucleic acid, and bioactive components including lutein, lutein fat, zeaxanthin, grape seed extract, chlorophyll and taurine. The device is mainly used for pre-pregnancy preparation of pregnant women, dosages thereof, pregnant women and wet nurses. The composition eliminates various factors causing birth defects from multiple systems, multiple links and multiple targets, can significantly reduce the total occurrence rate of birth defects, has the effect of improving memory, is beneficial to the health of parents and children, has no incompatibility, and does not generate any toxic or side effect after being taken for a long time.
Owner:BEIJING GUANWUZHOU BIOSCIENCE INSTITUTION (CN)

A method for preparing a metformin compound hypoglycemic oral solution

PendingCN122075608Asuppress original outputIncreased sensitivityOrganic active ingredientsMetabolism disorderMetformin hclOral solutions
This invention provides a method for preparing a metformin compound hypoglycemic oral solution, relating to the pharmaceutical field, comprising: step S1, pretreatment of traditional Chinese medicine components; step S2, enzymatic hydrolysis of the first group of traditional Chinese medicine components; step S3, supercritical extraction; step S4, preparation of mixed traditional Chinese medicines; step S5, preparation of inclusion complex; step S6, compound formulation; and step S7, post-processing. This method synergistically combines extracts from seven traditional Chinese medicines—bitter melon, phellodendron bark, astragalus root, kudzu root, rehmannia root, ginseng, and privet fruit—with metformin hydrochloride to form a metformin compound hypoglycemic oral solution, balancing the synergy, safety, and stability of traditional Chinese and Western medicines, thereby improving hypoglycemic effects while reducing the incidence of gastrointestinal adverse reactions to metformin.
Owner:CHONGQING CONQUER PHARML

Compound microbial agent applying device for preventing and treating radix astragali root rot

The utility model discloses a compound microorganism bacterium agent applying device for preventing and treating radix astragali root rot, and particularly relates to the field of radix astragali prevention and treatment, the compound microorganism bacterium agent applying device comprises a moving plate, a liquid storage tank is fixedly mounted on the upper surface of the moving plate, a supporting seat is fixedly mounted on the upper surface of the moving plate, and a lifting block is slidably connected to the inner wall of the supporting seat; a supporting sliding cover is fixedly connected to one side face of the lifting block, two telescopic sliding plates are slidably connected to the inner wall of the supporting sliding cover, communicating pipes are fixedly connected to one side faces of the two telescopic sliding plates, and nozzles movably communicate with one ends of the two communicating pipes. Through the cooperation of the lifting block, the fixing screw rod, the threaded locking ring and the strip-shaped hole and the design of the telescopic sliding plate, the threaded fixing knob and the strip-shaped groove, the height and the transverse distance of the spray head can be accurately adjusted, accurate spraying of a fungicide is achieved, the defect that spraying of an unmanned aerial vehicle is difficult to accurately control is overcome, the attachment amount of the fungicide on the root of a plant is increased, and the spraying efficiency is improved. The control effect is enhanced.
Owner:GANSU SHENYUANTANG PHARM CO LTD

Packaging bag (Minqin angelica, Dangshen, Huangqi tablet)

ActiveCN309875040SBiotechnologyCodonopsis
1. Name of the designed product: packaging bag (Minxian angelica, codonopsis, astragalus root tablets). 2. Use of the designed product: for packaging products. 3. Design points of the designed product: the combination of shape and pattern. 4. Picture or photo that best shows the design points: perspective view. 5. The designed product is a flat product, omitting the left view, right view, top view, and bottom view.
Owner:王志良

Special bacillus synbiotics for astragalus membranaceus as well as preparation and application of special bacillus synbiotics

The invention discloses a bacillus synbiotic special for astragalus membranaceus as well as a preparation method and application of the bacillus synbiotic. The bacillus synbiotic special for astragalus membranaceus comprises a bacillus subtilis strain GNRP-01A, a bacillus velezensis strain GNB3-7 and prebiotics, wherein the bacillus subtilis strain GNRP-01A, the bacillus velezensis strain GNB3-7 and the prebiotics are added into the prebiotics; the preservation number of the bacillus subtilis strain is CGMCC (China General Microbiological Culture Collection Center) NO: 34737, and the preservation number of the bacillus velezensis strain is CGMCC NO: 34738. The method solves the problems that chemical agents are used for preventing and treating radix astragali root rot and powdery mildew, pesticide residues are generated, and environmental pollution is caused, the morbidity of radix astragali root rot and powdery mildew is remarkably reduced by inhibiting growth of pathogenic bacteria, meanwhile, growth of radix astragali plants can be remarkably promoted, the yield can be increased, and the method is suitable for large-scale popularization and application. The economic benefit is improved; meanwhile, the drug resistance of chemical pesticide prevention and control and the ecological pressure of land are effectively reduced.
Owner:GANSU AGRI UNIV