The invention belongs to the field of biological
medicine, and particularly relates to a
traditional Chinese medicine composition with nerve soothing and sleep aiding effects, a preparation method and application, the composition is prepared by compounding spina date seed, platycladi seed,
astragalus membranaceus, longan
aril, medlar, dogwood, tuber fleeceflower stem, bighead atractylodes
rhizome,
angelica sinensis, poria cocos,
polygala tenuifolia,
ginseng, lily,
elecampane,
pericarpium citri reticulatae, liquorice, wheat and gamma-
aminobutyric acid. The preparation method comprises the following steps: S1,
drying and crushing
semen ziziphi spinosae,
semen boitae, rhizoma atractylodis macrocephalae, radix angelicae sinensis, radix aucklandiae and
pericarpium citri reticulatae, and performing
supercritical carbon dioxide extraction to obtain a
raw material volatile oil A; s2, crushing
astragalus membranaceus, longan
aril, wolfberry, dogwood, tuber fleeceflower stem, poria cocos,
polygala tenuifolia,
ginseng, lily, liquorice and wheat, mixing the crushed materials with
medicine residues obtained after the volatile oil is extracted in the step S1, and performing extraction, concentration and
drying to obtain
raw material powder B; s3, clathrating the volatile oil A obtained in the step S1 with
hydroxypropyl beta cyclodextrin, and
drying to obtain
raw material powder C; s4, mixing the raw material
powder B, the raw material powder C and gamma-
aminobutyric acid to obtain the
traditional Chinese medicine composition. The composition and the preparation thereof can improve the symptoms of lassitude, impatient temperament and
irritability caused by difficulty in falling asleep, dreaminess, easy waking and insufficient sleep of an
insomnia patient, and can deepen the sleep depth of the patient and prolong the
sleep duration.