The present invention relates to a composition for preventing or treating aging and aging-related diseases, comprising a
Sambucus spp. extract or a compound isolated therefrom as an
active ingredient. It has been confirmed that the
Sambucus spp. extract or the compound isolated therefrom exhibits effects of suppressing the expression of p16, which is a cellular aging biomarker, and promoting
autophagy. Accordingly, the
Sambucus spp. extract or the compound isolated therefrom of the present invention is expected to be applicable to the development of therapeutic agents,
functional health foods for amelioration, veterinary medicines, and
animal feed compositions for aging or aging-related diseases such as
idiopathic pulmonary fibrosis, cardiovascular diseases, diabetes, neurodegenerative diseases,
sarcopenia, and
osteoarthritis-related diseases.