The invention provides an ageing resisting purpose of verapamil, and specifically provides a purpose of the verapamil, or an optical isomer thereof, or pharmaceutically acceptable salt thereof to preparation of ageing resisting compositions or preparations. The experiment indicates that the verapamil can significantly prolong the life of threadworms; the threadworm health parameter evaluation experiment confirms that the verapamil can improve the movement behavior capacity, the body swinging capacity and the osmotic pressure stress capacity of the threadworms, and reduce vulva integrity defects; and ageing cell dyeing experiment indicates that the verapamil can reduce the ageing rate of human embryonic lung cells. Therefore, the verapamil can be applied to respects of prolonging life, delaying ageing, improving health physiological parameters, reducing the incidence rate of ageing related diseases and the like. The invention also provides products of ageing resisting medicines, health-care products, cosmetics and the like.