144 results about "Survival period" patented technology

The effect of anti-IL-6 receptor antibodies in suppressing cytotoxic T cell induction was examined. The results showed that CTL activity against alloantigens was statistically significantly reduced in mice treated with anti-IL-6 receptor antibodies as compared to mice not treated with antibodies and mice treated with a control antibody. The anti-IL-6 receptor antibody was also administered to recipients of a mouse model for allogenic heart transplantation. As a result, histopathological findings showed that inflammatory cell infiltration into transplanted hearts was suppressed and the survival period of transplanted hearts was significantly prolonged. Thus, the present inventors for the first time discovered that administration of anti-IL-6 receptor antibodies could suppress cytotoxic T cell induction and thereby suppress acute rejection after transplantation.

The utility model discloses a distributed cluster-based network construction method for the wireless sensing network. Via nodes, the method exchanges information in a neighborhood scope and obtains partial network information, on the basis of which the nodes are calculated in a weighed way to get the weighed value for competitive cluster head, and then the cluster head is selected and clusters are formed to put an end to the cluster formation of the network. The invention brings the partial network information that is commanded by the nodes into full play, and obtains the weighed value of the most competitive cluster head in a weighed way, thereby realizing the most cluster-based optimization of the network and the load balance of the system. The nodes weighed value of the invention is a dynamic change in the cluster-based process, and a more optimized cluster-based result is accessible. Compared with the prior cluster-based network construction method, the invention has the advantages of easy realization of load balance, the elongation of network survival period and better performance, meets different requirements of different application circs on network performance, and has relatively good adaptability and extensibility.

The invention relates to a wireless sensor network clustering routing method based on dual cluster head. The method comprises the following steps: a base station in a wireless sensor network sends an initialization message to the whole network; each node in the wireless sensor network reports a personal position, residual energy and node ID information to the base station; the base station acquires the position, the ID and the residual energy of the node in the wireless sensor network, and counts the total number of the node; the base station horizontally partitions a distribution region according to the counted information; a candidate main cluster head is elected according to the position, the ID and the residual energy of the node; different competitive radiuses are set according to a distance between the candidate main cluster head and the base station, a final main cluster head is elected in the competitive radius, and the final main cluster head is organized into a cluster. An intra-cluster transmission way and an inter-cluster transmission way are provided in data transmission. The technical scheme provided by the invention can solve the problem that the network survival period is short.

The invention discloses an identity authentication method for a Hadoop cluster. The method comprises the following steps: step one, a client sends a request to an authentication server to request for the ticket granting, the request is sent to the authentication server in a plaintext way, the request message comprises a user name, an authorization server name, a valid survival period, the first random number and a user located Kerberos field user information; step two, after receiving the request message of the client, the authentication server firstly finds a key of the user in a local database according to the user name, if the finding is successful, the authentication is continued. By adopting an authentication mode based on the PKI, the command of the user is unnecessary to save on the KDC, the risk point of the system is reduced, and the security of the Hadoop cluster identity authentication is greatly improved.

The invention discloses a wireless sensor network routing energy-saving method with load balancing. The method comprises: step one, a wireless sensor node is defined randomly in a limited area; step two, a fitness functions of cluster head selection is listed; step three, a cluster head is selected by using an improved particle swarm algorithm; step four, the cluster head carries out broadcasting on other nodes to express the identity of the cluster head; step five, a fitness functions of relay node selection is listed; step six, a relay node is selected by using an improved particle swarm algorithm; step seven, a common node sends environment information detected by the common node to the cluster head; step eight, the cluster head carried out data fusion and sends the fused data to the relay node; and step nine, the relay node sends the data to a base station and communication is completed. Compared with the prior art, the provided wireless sensor network routing energy-saving method has the following beneficial effects: high energy consumption of the cluster head in the traditional wireless sensor network can be reduced; the energy consumption of the whole network can be balanced; and the survival period of the whole network can be prolonged.

The invention relates to a multimedia sensor network routing scheme guaranteeing service quality, which refers to a wireless multimedia sensor network routing method, and is mainly used for solving the transmission problem of the data of a plurality of task flows existing in a wireless multimedia sensor network. The wireless multimedia sensor network routing scheme realizing guaranteeing the service quality is mainly characterized in that according to the own characteristics of a node, a role played in a routing path is automatically applied; according to cost on a link path, an optimal node is selected to establish a plurality of routing paths with different task flows; and when network topology changes, then routing path is dynamically renewed. By using the method of the invention, when the network is under a situation that a plurality of multimedia task flows are transmitted and applied, the multimedia task flows are real-timely and effectively transmitted, and the aim of reducing network congestion rate, increasing network huff, fully playing the function of each node in the network, balancing network energy consumption, effectively utilizing the resources of the whole network, and improving the survival period of the whole network is achieved.

The invention discloses a route equalization method of multi-jump cooperative energy of a body area network under the condition of ensuring service quality, comprising the following steps of: arranging a plurality of nodes on a human body; dividing the energy conditions of the nodes into a full grade, a fuller grade, a medium grade, a lower grade and an empty grade; dividing businesses generated by the nodes into a business grade with a high real-time requirement and a business grade with a low real-time requirement; when establishing a route, calculating the sum of energy consumed by other nodes in each path except for a source node and a target node and introducing energy factors in the calculating process; selecting a path with minimum sum of the consumed energy as a route for the businesses with lower real-time requirement, and selecting a path with least jumping number as a route for the businesses with higher real-time requirement; and also adopting a cooperative transmission method in a transmission process after establishing the route. The measures finally ensure that the energy of each node in the network is equally consumed, thereby ensuring the communication of the network and prolonging the survival period of the network.

The invention relates to a chimeric antigen receptor, nucleic acid encoding the same, cells expressing the chimeric antigen receptor, and application of the chimeric antigen receptor in preparing drugs for treating tumors. The chimeric antigen receptor comprises at least one extracellular structural domain, an optional membrane spanning structural domain and at least one intracellular co-stimulation signal transduction structural domain, wherein the extracellular structural domains involve CD19 antigen recognition binding structural domains. The chimeric antigen receptor has a longer in-vivo survival period after being subjected to humanized transformation, and the complete remission period of a patient can also be prolonged accordingly.

The invention relates to a special base stock bag for oil-tea tree seedling cultivation and a preparation method thereof. Base stock comprises northeast peat soil, slow release fertilizer, a powder type water-retaining agent, bark grains, saw dust, rice hulls, yellow-clay fine powder, vermiculite and perlite. The preparation method of the base stock bag includes steps of raw material preparation, single term processing, raw material mixing, base stock bagging, long bag cutting and the like. The base stock bag greatly improves survival rate of seedlings and shortens a seedling growing period, the slow release fertilizer achieves even fertilizing matching with seedling fertility required rhythm, the water-retaining agent guarantees a water demand of seedlings in a survival period, and the northeast peat soil balances breathing of seedling roots and water retaining. The materials are easy to obtain, and the special base stock bag is suitable for industrialized production of grating seedlings of oil-tea tree seedlings.

The invention discloses a vertex-betweenness-based cluster head selection method in randomly distributed wireless sensor networks. The vertex-betweenness-based cluster head selection method comprises the steps of calculating vertex betweennesses by utilizing an adjacent matrix G, then calculating the vertex betweenness of each branch cluster, selecting the vertex with the largest vertex betweenness, and finally setting the largest vertex betweenness as a cluster head in a cluster in the cluster head selection process. The cluster head selection method utilizes a node with the largest influence as the cluster head, relatively reduces the distance from the cluster head node to other nodes, and solves the problem that communication time span from the cluster head node in the cluster to other nodes in the wireless sensor networks is large. According to the cluster head selection method, any hardware equipment does not need to be added, the average distance between the cluster head nodes in the cluster is reduced by utilizing the influences of the clusters, the method can reduce network energy consumption for cluster head selection in each turn and balance loads, obtains a reasonable network topology and the networks with longer survival periods, and has popularization and application values.

The invention discloses multi-lateral root fruit tree bridging technology, which is a method for performing single-head bridging on a one-year high-quality seedling of a pyrus betulaefolia rootstock which is transplanted successfully on a plurality of sides, 50 to 70 centimeters away from the ground surface, of a fruit tree trunk when a fruit tree is in a growing season. By bridging the fruit tree by the method, the rootstock and the high-quality seedling have no impedance response basically; the root is supplied with sufficient nutrition so that the fruit tree obtains increased nutrients; therefore, harvest rate and fruit quality are improved; and the disease resistance of the fruit tree is improved and a survival period is prolonged.

The present invention relates to a traditional Chinese medicine which is used for the treatment of cancers, in particular to a Chinese traditional patent medicine for treating lung cancer, cervical cancer, liver cancer, breast cancer, pancreatic cancer and malignant lymphoma. The present invention is characterized in that the present invention includes the raw materials with the following mix ratio by weight: 20 to 40 parts of honeycomb, 15 to 25 parts of oldworld arrowhead corm, 20 to 40 parts of hiraute shiny bugleweed herb, 30 to 50 parts of dahurian patrinia herb, 10 to 20 parts of gecko, 10 to 20 parts of pillbug, 30 to 50 parts of spreading hedyotis herb, 30 to 50 parts of common andrographis herb, 30 to 50 parts of barbed skullcap herb, 20 to 40 parts of common selfheal fruit-spike, 10 to 20 parts of Chinese thorowax root, 10 to 20 parts of figwort root and 10 to 20 parts of ginseng. The present invention has the effects of clearing heat, removing toxicity, promoting blood circulation, removing blood stasis, relieving swelling, resolving hard mass, benefiting qi and easing pain, which is applicable to the treatment of the patients with various mid-advanced tumors; the present invention can alleviate the clinical symptoms of the tumor patients, improve the cellular immune function of the patients, delay the development and the transfer of the cancers, improve the quality of life of the patients and prolong the survival period.

The normal temperature and sub-normal temperature in vitro heart preserving perfusate as one kind of organ preserving matter consists of basic electrolyte, energy matter and protecting matter. Each liter of the heart preserving perfusate contains NaCl 5.0-7.0 g, KCl 0.3-0.5 g, NaH2PO4 .H2O 100-150 mg, MgSO4 50-100 mg, NaHCO3 3.0-5.0 g, L-argine 70-100 mg, histidine 30-60 mg, L-cystine 50-70 mg, L-methionine 10-50 mg, levo glutamine 500-700 mg, L-lysine 100-170 mg, glycine 10-50 mg, L-isoleucine 70-150 mg, L-serine 30-50 mg, L-leucine 70-150 mg, L-tryptophane 10-20 mg, L-tyramine 80-150 mg, L-valine 70-150 mg, L-threonine 80-150 mg, choline chloride 3-8 mg, vitamin B2 0.5-3 mg, pantothenic acid 3-g mg, folic acid 3-8 mg, pyridoxal 3-10 mg, nicotinamide 3-10 mg, etc. The present invention has the effects of preserving in vitro heart efficiency, reducing rejection reaction of organ and prolonging the survival period of organ.

The invention provides an updating method of fragment popularity, which comprises the steps of segmenting files into n data fragments, and calculating the popularity of each data fragment; calculatingeach block calculation survival period of all the files; calculating the duplicate placement rating of each fragment based on the fragment popularity and carrying out distribution; recording access behaviors including access positions, the corresponding fragments, access time and access frequency to all the files by taking time T as a cycle; re-calculating the popularity of block-i when arrivingk * T time at each time from adding the files into a distribution network; re-calculating the duplicate placement rating of the each data block according to the new popularity value obtained by calculation and adjusting the number of duplicates of data according to the new rating. The method can periodically collect user access information, carry out updating of the popularity of the data fragmentblocks under the premise of as little as re-segmentation and distribution, lead the popularity to be closer to actual access rules of a user, calculate the duplicate placement method according to thenew popularity and adjust the number of the duplicates.

The invention relates to the technical field of medical molecular biology and provides a method for detecting the serum marker of pancreatic cancer. The pancreatic cancer has high grade malignancy, difficult early diagnosis and poor prognosis, and the pancreatic cancer also lacks really effective solution, with surgical resection as the only therapeutic method to prolong survival period. Unfortunately, most of pancreatic cancer patients are in the advanced stage (TNM belongs to III and IV stages) and miss the surgical option. The invention aims at providing a method for detecting the serum marker of pancreatic cancer and applying the method to early diagnosis of pancreatic cancer and clinical judgment of laparotomy indication. The study proves that in the invention, the expression level of miR-196a in the serum is closely related to the postoperative survival period of pancreatic cancer; the study later proves that the relative expression abundance of miR-196a can well distinguish resectable pancreatic cancer (TNM belongs to I and II stages) from pancreatic cancer in advanced stage (TNM belongs to III and IV stages), so the method in the invention can be used for detecting the serum marker microRNA-196a of pancreatic cancer, and the method further has the advantages of convenient detection, good sensitivity and high accuracy.

The invention discloses a cluster-based CTP (coordinated test program) routing protocol, which is suitable for a cluster-based wireless sensor network and adopts the design of a routing topology tree scheme of the wireless sensor network. Different from the conventional method in which research situations of clusters are not different or only the research situation of one cluster is different, the cluster-based CTP routing protocol takes a multi-cluster situation into consideration and has a practical meaning better. With the adoption of a scheme of carrying out routing selection at regular intervals, the cluster-based CTP routing protocol solves the problems that the survival period of the wireless sensor network becomes shorter since the energy consumption of some nodes in the wireless sensor network is too fast, and thus the stability and the survival period of the wireless sensor network are greatly improved and prolonged. On basis of ensuring high efficiency, reliability and effectiveness of performance, the routing protocol disclosed by the invention takes the differences of action properties of the nodes at different stages into consideration. While ensuring the integral performance optimization of the network, the cluster-based CTP routing protocol effectively prolongs the survival time of the network, enhances the energy efficiency of the network and efficiently utilizes system resources by establishing a routing topology tree of the wireless sensor network.

The invention relates to a method for improving the genetic transfer efficiency of gene-transferred soybean. Wherein, it uses agricillin soybean cotyledon transfer system and germ sharp transfer system to obtain transfer adventitious bud; said adventitious buds without growing root and seed are directly made into graft, via cleft grafting method to be grafted on the soybean seed stock; the graft and the stock via combine period, recover period, fusion period and survival period can improve the gene transfer efficiency of soybean. The grafting can improve the survival rate of plant more than 90%, to shorten the gene transfer period and improve the gene transfer research.

The invention relates to a management method of the remote component lifecycle. It includes: establishing the stub object and the agency object according to the remote component object; the reference counter value of the stub object and the agency object is added or decreased by using the AddRef and the Release method. In the proper condition, it releases the system resource and writes off the related registered information. The invention controls the survival period of the component object, the stub object and the agency object by counting the number. So it can decrease the remote consumption to accord with the component object module. The user can manage the lifecycle in the local position.

The invention relates to a self-adaptive router soft switching method for a wireless sensor network, which comprises the following operation steps that: a router ensures the time slot request, the initial router building, the terminal node router building and the initial router soft switching; and a router ensures the time slot and router updating, the terminal node router soft switching and the data transmission. In the self-adaptive router soft switching method, a router node can be flexibly switched according to the real-time state of the node, further, the transient network disconnecting problem of the node in the moving process can be effectively avoided for reducing the data loss rate, simultaneously, a balance processing mechanism on the router energy and the integral energy is introduced in the router switching process, further, the survival period of the whole network can be effectively prolonged. The self-adaptive router soft switching method has a simple realization mode and is applicable to a wireless sensor network with small scale and movable performance nodes.

The present invention discloses a slow release system of Temozolomide as local slow release medicine and biodegraded polymer for treating malignant brain tumor, and the slow release system is implanted into operated area of excising malignant brain tumor for local slow release treatment of malignant brain tumor and prolonging the survival period of the patient. The present invention consists of Temozolomide and biodegraded polymer material in the weight ratio of 1.5 to 10. Temozolomide is fused into biodegraded polymer, and through the corrosion of the polymer and hydrolysis of the polymer, the medicine is released slowly, continuously and stably to act. The polymer is PLA, PGA, PLGA, PFAD-SA and / or the copolymer of p-carboxyl phenoxyl propane and sebasic acid.

The invention provides a wireless sensor network data flow rate shunting routing method based on multipath, and relates to a wireless sensor network technology method. According to the method, an MDFD data flow rate shunting method is used for balancing the energy consumption of network nodes, so that all network nodes can maintain the balanced energy consumption, so that the network scales can basically maintain unchanged in the survival period; in order to save the calculation expenditure of sensor nodes during the proper path selection, the MDFD uses the reliability evaluation parameter for selecting the proper path; the node state information is used for calculating the reliability evaluation value of the single node; when the node rest energy is considered, only the nodes being about to take part in the next hop of routing campaign are considered. The method has the advantages that the energy consumption problem of the wireless sensor nodes can be effectively solved; the life period of a wireless sensor network can be effectively prolonged; the condition of work resistance of the wireless sensor network caused by the energy consumption problem is relieved.

The invention relates to a safety identification method of intelligent card service in the controllable network protocol network, wherein S1, user identifies the intelligent card via the IP network service platform server, while the card contains key and card number; S2, the identify server initializes the battle word process to the user to request identification; S3, the user via the battle word obtains the service application public key and the survival period; S4, the user uses the identification key to encrypt the relative information, to enter into the service application process. With said invention, the safety identification process has high safety, few steps, quick response, simple management and low cost.

An internally degradable 3D frame material with tubular structure for culturing liver cells in body is prepared through such steps as preparing mould from paraffine and stearic acid, preparing degradable high-molecular solution of polylactic acid, adding pore-forming agent, coating on the mould, physical and chemical treating, treating it with anti-coagulating medicine, and sterilizing. Its advantages include high cell and blood compatibility, and high survival period of liver cells.

The invention provides a stagnation-removing decoction oral liquid and a preparation method thereof. The preparation method of the stagnation-removing decoction oral liquid comprises the steps: taking medicinal materials according to a prescription of the stagnation-removing decoction oral liquid for drug preparation; placing the medicinal materials in an extraction tank, and extracting for multiple times; merging the extract liquids and concentrating; carrying out alcohol precipitation refining on the concentrate; filtering, and recycling ethanol; adding pure water to regulate the total amount, and mixing evenly to obtain the oral liquid finished product. The stagnation-removing decoction oral liquid prescription comprises a part or all of the medicinal materials comprising herba scutellariae barbatae, coix seed, radix astragali, full scorpion, hedyotis diffusa, cordate houttuynia, curcuma zedoary, ganoderma lucidum and centipede. The stagnation-removing decoction oral liquid has better curative effects in middle-late stage lung cancer, can alleviate clinical symptoms of patients with middle-late stage lung cancer, improves the cell immune function of the patients, prevents lung cancer development and metastasis, improves the life quality of the patients, and prolongs the survival period. Moreover, compared with western medicines, the stagnation-removing decoction oral liquid has smaller side effects; and compared with traditional Chinese medicine decoctions, the stagnation-removing decoction oral liquid is more convenient to take, and is also well convenient to store and carry.

The invention relates to functional humic acid water soluble fertilizer containing composite microbes and a preparation method thereof, and belongs to the field of agricultural application microbial fertilizer. The functional humic acid water soluble fertilizer containing composite microbes is prepared from the following ingredients of composite microbial bacterial powder, humates, nitrogen sources, phosphorus sources, potassium sources, deflocculants and anticaking agents. Compared with the prior art and products, the fertilizer has the beneficial effects that the process is simple; the property is stable; the fast dissolution, fast action, high mixing performance, application convenience, high microbial strain purity, high activity and long survival period are realized.

The invention discloses a planting method of avenue trees, which comprises the steps including (1) hole digging, (2) sapling treatment, (3) planting and (4) watering and fertilization, wherein during the hole digging, weeds are cleaned by firing, a disinfection treatment is carried out, and base fertilizers are applied; during the sapling treatment, a sapling undergoes root breaking and cutting and is then treated by a rotting agent, the sapling is then covered by soil and watered, and a tree root main body is wrapped by a biological thin film; during the planting, the sapling is planted, the tree root main body is watered thoroughly, and a plastic pipe with a diameter between 30 mm and 100 mm is embedded around the planting hole; and during the watering and the fertilization, fertilizers are applied by the plastic pipe. In the planting method of the avenue trees disclosed by the invention, the young saplings are transplanted on two sides of a road, the tree root is treated by the sterilization and the base fertilizer applying and wrapped by the organic matter thin film, and root moisture loss and farmyard manure applying during a planting survival period of the sapling are avoided, so that a survival rate of the avenue tree saplings can be increased, and planting cost can also be reduced. Farmyard manures can be applied after survival of the avenue tree saplings, the fertilization can be carried out at daytime, the fertilizers without odors will not disturb pedestrians, the fertilization is carried out quickly and conveniently, and soil at the tree roots needs not to be dug during the fertilization.

The invention discloses a traditional Chinese medicinal composition for treating lymph cancer and belongs to the technical field of traditional Chinese medicines. The medicinal active ingredients of the composition are prepared from the following raw materials in parts by weight: curcuma aromatica, ground beetle, red peony root, selfheal, pericarpium citri reticulatae viride, radix bupleuri, salvia miltiorrhiza, Chinese angelica, rhizoma atractylodis macrocephalae, trogopterus dung, ligusticum wallichii, raw rehmmania, scrophularia ningpoensis, rhizoma anemarrhenae, turmeric, pinellia ternata, fructus psoraleae, radix angelicae pubescentis, rhizoma acori graminei, medlar, rhizoma sparganii, curcuma zedoary, monkhood, pseudo-ginseng, raw oyster and liquorice. The traditional Chinese medicinal composition has the effects of strengthening spleen, harmonizing stomach, tonifying qi, producing blood, tonifying liver and kidneys, softening hardness and removing stasis, can be used for correcting body imbalance, removing relapse factors of tumors and reducing the opportunity of transfer. When cancers get better, the physical strength can be gradually restored, the immunity can be gradually enhanced, the diet and sleeping conditions of patients can be improved, the constitution of patients can be improved, and the survival period and living quality of patients can be improved.

The present invention belongs to the field of medicine technology, and is one saccharide composition for protecting microecologic preparation. The microecologic preparation for maintaining health includes bifidobacterium, lactobacillus, etc. The saccharide composition consists of hyaluronic acid and mycose and has double and synergistic protection on microecologic preparation in drying and storage process. The saccharide composition can raise the survival rate of microbes, prolong the survival period, and makes it possible to maintain microecologic preparation.