The application relates to application of a
probiotic preparation in improving dairy cow
mammary gland health, and belongs to the technical field of
probiotic preparation application. The application finds that a microbial preparation prepared from
Akkermansia muciniphila is helpful to maintaining the dairy cow
mammary gland health, thereby improving the
milk yield and milk quality of the dairy cow, by promoting the proliferation of the dairy cow
mammary gland epithelial cells, inhibiting the
apoptosis of the dairy cow mammary gland epithelial cells (alleviating mammary gland
inflammation and promoting the expression of
milk secretion related genes). The preparation is
safer, more efficient and
pollution-free, is non-toxic and harmless, does not cause negative influence on the health of the dairy cow, and is easy to obtain, easy to culture in a large amount, simple to operate, easy to obtain raw materials and simple in method, so that the cost of manpower and
material resources can be reduced.