364 results about "Iron-deficiency anemia" patented technology

Embodiments of the invention provide patches for the transdermal delivery of iron-containing compositions to an individual suffering from an iron deficiency. Many embodiments provide an iontophoretic patch for the transdermal delivery of a therapeutically effective amount of iron. The patch comprises an electrode and a reservoir containing a composition comprising ionic iron for the delivery of the therapeutically effective amount of iron. Various embodiments provide methods of using embodiments of the iontophoretic patch for delivering a therapeutically effective amount of iron to an individual suffering from one more forms of iron deficiency including iron deficiency anemia. Such methods can be used for treating and / or preventing the iron deficiency. The amount of delivered iron can be adjusted depending upon various treatment parameters such as patient weight and type and amount of iron deficiency.

The invention relates to a coarse-cereal dried bean curd roll and a preparation method thereof. The coarse-cereal dried bean curd roll is a bean product which is made by raw materials such as 45-85 percent of soy beans, 10-35 percent of black beans, 5-30 percent of green beans, 0-20 percent of peanuts and the like through steps of soaking, pulp grinding, pulp stewing, roll formation and drying. The coarse-cereal dried bean curd roll contains rich nutrients in various coarse cereals such as the black beans, the soy beans, the green beans and the peanuts, is rich in various vitamins, dietary fibers and minerals such as calcium, iron and the like and can promote the balance of dietary nutrition of people; when people eat the coarse-cereal dried bean curd roll for a long term, the effects of promoting blood circulation, reducing cholesterol, improving mental function, complementing calcium, preventing osteoporosis, preventing iron-deficiency anemia and the like can be achieved; the coarse-cereal dried bean curd roll is dark yellow and glossy, the rolls are even, the rehydration performance is good, the taste is flexible and unique, the roll is fragrant to taste and the aftertaste is long; and the yield of the process is high, the quality of the obtained product is high, the production cost is lower and the economic benefit is considerable.

The invention relates to an enzymolytic lactoprotein ferrous complex, a microcapsule iron supplement and a preparation method thereof. In the preparation method, ferrous salt is complexed with an enzymolysis product of lactoprotein, which can improve solubility of iron salt under an alkalescent intestinal condition, improves absorptivity and availability of iron and ensures a safe and pollution-free preparation process; a proper coating material is adopted for microencapsulating the enzymolytic lactoprotein ferrous complex to prepare the microcapsule iron supplement agent of the enzymolytic lactoprotein ferrous complex; the iron supplement agent can mask self-odor of the ferrous salt, prevent the ferrous iron from oxidation, gradually release Fe under the alkalescent intestinal condition to ensure high biological absorptivity and biological availability of the Fe, and has no toxic and side effect; and the enzymolytic lactoprotein can prevent and treat iron-deficiency anemia, and has physiological functions of resisting oxidation, adjusting immunity, lowering blood pressure and the like.

An iron-dextran compound for parenteral treatment of iron-deficiency anemia comprises hydrogenated dextran having a weight average molecular weight (Mw) between 700 and 1,400 Daltons, preferably approximately 1,000 Daltons, a number average molecular weight (Mn) of 400 to 1,400 Daltons and wherein 90% by weight of the dextran has molecular weights less than 2,700 Daltons and the Mw of the 10% by weight fraction of the dextran having the highest molecular weights is below 3,200 Daltons, said hydrogenated dextran having been subjected to purification by membrane processes having a cut-off value between 340 and 800 Daltons, in stable association with ferric oxyhydroxide. The compound is produced by using membrane processes to eliminate dextrans of higher molecular weights than approximately 2,700 Daltons and membrane processes to remove saccharides of molecular weights below approximately 340 Daltons from hydrogenated dextran before precipitating ferric hydroxide in the presence of said dextran followed by heat treatment and purification.

The invention discloses feed for postpartum sow in a lactation period of 1-20 days and a preparation method thereof. The feed comprises the following raw materials: maize, wheat bran, soybean meal, egg yolk, powdery black fungus, soybean oil, table salt, a microelement premix and a traditional Chinese medicine additive. The feed has the benefits that based on the treatment principle of ferrum supplementing, spleen strengthening, qi invigorating and hematopoiesis, the traditional Chinese medicine additive contained in the feed cooperates with other raw materials to together act, so that the demand of the sow in the lactation period for nutrition is satisfied, and the feed has the advantages of high efficiency, low toxic and side effects, no residue, no medicine resistance, no pollution to the environment, enhancement of organism resistance, short treatment period, and no repeatability on the treatment of piglets suffering an iron-deficiency anemia disease.

A Chinese medicine in the form of table, capsule, particle, powder, pill, etc for treating aplastic anemia, iron-deficiency anemia, and leukocytopenia is prepared from 21 Chinese-medicinal materials including donkey-hide gelatin, Chinese angelica root, astragalus root, mother wort, etc. Its advantage is high curative effect.

A compound of ferrous L-threonate with structure (I), its compostions and methods useful for iron supplementation for mammals, particularly for human body to improve and treat nutritional iron-deficiency anemia, blood loss anemia and hemolytic anemia.

The invention relates to a double-layer sustained release tablet for supplementing iron, the double-layer sustained release tablet consists of a sustained release layer and a quick release layer laminating with each other at the weight ratio of 1:0.25-1:4; the sustained release layer consists of an iron-containing compound, a sustained release framework, an adhesive, a lubricant and a filler; the quick release layer consists of a traditional Chinese medicine for enriching the blood and / or invigorating vital energy, a filler, a disintegrating agent, an adhesive and a lubricant; the quick release layer can also be added with vitamins. In the double-layer sustained release tablet, by arranging the iron-containing compound in the sustained release layer and the traditional Chinese medicine in the quick release layer, the iron element is released slowly and uniformly, which increases the absorption rate, avoids gastrointestinal reaction caused by high-content iron; meanwhile the double-layer sustained release tablet supplements iron element and the traditional Chinese medicine which has the functions of enriching the blood and invigorating vital energy, thus fully improving the nutritional status caused by iron deficiency anemia and improving iron supplementing effect.

Beverages and powdered beverage mixes fortified with ferric EDTA as an iron source are provided. The beverages and beverage mixes fortified with ferric EDTA according to this invention have superior iron bioavailability and excellent storage stability. The present invention also is directed to a method of using such ferric EDTA-fortified beverages to prevent or treat iron-deficiency anemia in individuals by administering the iron fortified beverage of the invention in an effective amount to an individual in need thereof.

The invention discloses a pharmaceutical composition as an iron supplement agent, which comprises ferrous glycinate, antioxidant and medicinal carrying agents. The invention also discloses preparations containing the composition, the process for preparing the composition and the preparations, and the use of the composition in preventing and treating iron deficiency. The composition is capable of appreciably improving the absorption ratio of iron in intestinal tract, thereby improving iron-deficiency anemia effectively.

The invention discloses a health-care food of iron zinc calcium tablets and a production method thereof. The iron zinc calcium tablets consist of chewable tablets, calcium carbonate, ferric pyrophosphate, zinc gluconate, lactose, sucrose, sorbitol, mannitol, maltodextrin, casein phosphopeptide, milk powder, fruit powder, citric acid, sodium citrate, magnesium stearate, silicon dioxide and other raw materials by parts by weight. The prepration method comprises the steps of preparing the raw materials by parts by weight, smashing, screening, weighing the raw materials, granulating, baking, mixing, tabletting and coating. The product has the effects of reinforcing spleen, promoting appetite, improving myocardial ischemia, supplementing blood and calcium, improving sleep and preventing iron deficiency anemia and other diseases, thereby being the health-care product which can not only strengthen the body, but also improve the immunity and the anti-disease ability of the human body.

The present invention relates to an infant formula milk powder capable of preventing and alleviating infant iron deficiency anemia and a preparation method thereof. The formula milk powder comprises components such as vegetable oil, fresh milk, whey powder, lactose powder, whey protein powder, oligosaccharides, complex vitamins and complex minerals, wherein the lactoferrin and vitamin C, or alternatively, an iron source (calculated as iron), lactoferrin and vitamin C are maintained in the appropriate mass ratios, and the formula milk powder of the present invention is obtained by performing mixing, homogenizing, cooling, concentrating and spray-drying, packaging or directly using a step-by-step mixing method. The formula milk powder comprises appropriate amounts of vitamin C and lactoferrin, as well as an appropriate amount of iron source as further provided, and the three are combined according to an appropriate proportion, so that the combination of the three kinds of the substances have a synergistic effect, and the absorption and utilization rate of iron are increased dramatically, thereby not only achieving the desirable iron supplementation effect, but also preventing and alleviating the phenomenon of infant iron deficiency anemia.

The invention relates to a production process of convenient preserved egg and pork congee, which belongs to the technical field of food processing. The production process comprises the following steps of: curing rice and sticky rice, pre-cooking the rice and the sticky rice, processing preserved eggs and fresh pork, and canning the food. The convenient preserved egg and pork congee is prepared by mixing the rice and the sticky rice according to a certain ratio and matching appropriate auxiliary ingredients. The preserved egg and pork congee is full of nutriments, is capable of promoting appetite and the digestive absorption of nutrients and improving iron-deficiency anemia, is less in cholesterol, has the functions of warming spleen and stomach and is suitable for being appropriately taken by ordinary people. Meanwhile, the convenient preserved egg and pork congee conforms to a modern diet concept and is fast food for supplementing nutrients of modern people with a rapid pace of life.

The invention relates to an infant formula milk powder which can be used for preventing and improving iron-deficiency anemia of infants and a preparation method of the infant formula milk powder. The infant formula milk powder comprises the following components of vegetable oil, fresh milk, whey powder, lactose powder, whey protein powder, oligosaccharide, compound vitamin and compound mineral substances and the like; suitable mass ratio of lactoferrin to vitamin C or an iron source (measuring in iron) to the lactoferrin and the vitamin C is kept; and the formula milk powder is obtained by adopting mixing, homogenizing, cooling, concentrating, spray-drying and packaging or directly adopting a step-by-step mixing method. As proper amount of vitamin C and lactoferrin are contained in the formula milk powder, moreover, proper amount of the iron source is added, and the the vitamin C, the lactoferrin and the iron source are combined at a proper ratio, so that the three substances can exert the synergistic effect; and the absorption utilization rate of the iron is greatly improved, not only is the iron supplementing effect good, but also the phenomenon of the iron-deficiency anemia of the infants can be prevented and improved.

A composite medicine for treating the hemorrhagic anemia, iron-deficiency anemia and nutritional anemia is prepared from the arnono acid chelated iron, one or more Chinese-medicinal materials for nourishing blood, and pharmacologically, acceptable salt. Its advantages are high curative rate and biologic utilization rate, and low irritation to enterogastric tract.

This invention is directed to medical equipment and can be used for elevation of resistance of a human body against various pathologies including bronchial asthma, hyperplastic anemia and iron deficiency anemia, neurocirculatory dystonia, hypertension, obesity. This instrument can also be useful for treatment and prevention of respiratory and metabolic dysfunctions, for enhancement of non-specific compensatory capabilities of a human body and its aerobic output, as well as for improving physical fitness and regenerative ability of athletes, and reducing negative side effects of ionizing radiation.

Embodiments of the invention provide patches for the transdermal delivery of iron-containing compositions to an individual suffering from an iron deficiency. Many embodiments provide an iontophoretic patch for the transdermal delivery of a therapeutically effective amount of iron. The patch comprises an electrode and a reservoir containing a composition comprising ionic iron for the delivery of the therapeutically effective amount of iron. Various embodiments provide methods of using embodiments of the iontophoretic patch for delivering a therapeutically effective amount of iron to an individual suffering from one more forms of iron deficiency including iron deficiency anemia. Such methods can be used for treating and / or preventing the iron deficiency. The amount of delivered iron can be adjusted depending upon various treatment parameters such as patient weight and type and amount of iron deficiency.

The invention provides a preparation method and application of a low-molecular porphyra haitanensis polyferose compound. The method is characterized in that low-molecular porphyran is used as a raw material and degraded by redox reaction to obtain low-molecular-weight porphyran with the molecular weight being less than 10000Da; and the polyferose compound synthesized by heating the porphyran and ferric chloride together can be dissolved well and exist stably under a physiological pH condition, and also shows a good effect in the iron-deficiency anemia mouse model experiment. The preparation method has the advantages of being simple and convenient in operation, stable in preparation process, low in preparation cost, etc.; and the preparation method also shows wide applicability to raw materials, namely, any polysaccharide with a proper molecular weight range is applicable to the preparation method.

This invention discloses a process for preparing polyferose from oligosaccharides, lye and ferric salt. The method operates at a water / iron weight ratio above 3.5, and adds lye by flow addition. Besides, the method adopts ethanol as the precipitant and low-speed centrifuge to separate and purify the product. Polyferose can be used to treat iron deficiency anemia, and has such advantages as good iron-supplement effect, and few gastroenteric side effects.

The invention discloses sodium iron chlorophyllin-chitosan / sodium alginate microcapsules and a preparation method thereof. In the method, chitosan / sodium alginate is used as a capsule material, sodium iron chlorophyllin is used as capsule content, and the sodium iron (II) chlorophyllin is microencapsulated by an emulsification-gel method. The preparation method comprises: dissolving sodium iron chlorophyllin in sodium alginate solution at a certain concentration, adding the prepared solution in vegetable oil containing Span-60, and stirring at high steep and emulsifying for 20 minutes; dripping acetic acid aqueous solution containing 2.0-percent chitosan and calcium chloride, continuously stirring for 30 minutes, standing for 2 hours and removing an oil phase; and washing the microcapsules with petroleum ether and isopropanol for three times respectively, performing suction-filtration, and drying at room temperature to obtain the sodium iron chlorophyllin-chitosan / sodium alginate microcapsules. The chitosan which is a natural polysaccharide with high biocompatibility and biodegradability and the sodium alginate serve as sustained and controlled release agent and targeting preparation, the sodium iron chlorophyllin is encapsulated in the center of the microcapsules to be protected from instability caused by change in a light or placing condition, a new formulation is provided in pharmacy, and the microcapsules are suitable to be further developed and used as iron-supplying health-care food and new medicinal preparation for treating iron-deficiency anemia, and have a bright application prospect.

The present invention relates to a pharmaceutical composition including an active pharmaceutical ingredient for the treatment of iron-deficiency anemia and related disorders. The active pharmaceutical ingredient is preferably carbonyl iron. The formulation of the pharmaceutical composition of the present invention ensures enhanced absorption of iron in its ferrous form. Also contemplated by the present invention are the methods of making the pharmaceutical composition.

The invention discloses an oat alga beverage. The oat alga beverage is characterized by being prepared from the following raw materials by weight: 21 to 24 parts of glossy ganoderma, 1 to 2 parts of ginseng, 1 to 2 parts of hairyvein agrimony, 13 to 15 parts of agaricus brasiliensis, 16 to 17 parts of cabbage, 15 to 18 parts of alga, 17 to 21 parts of oat, 7 to 9 parts of arborvitae seed, 13 to 15 parts of damiana leaf, 10 to 13 parts of cloud and mist tea, 15 to 18 parts of rose flower, 16 to 19 parts of cherry, 10 to 13 parts of bone fossil of big mammals, 5 to 7 parts of an auxiliary agent and a proper amount of water. The beverage provided by the invention is rich in magnesium and vitamin B1 and contains phosphorus, potassium, iron, pantothenic acid, copper and fiber; the beverage can reduce cholesterol, has an auxiliary curative effect on fatty liver, diabetes, constipation, anaemia and the like and is capable of preventing and treating iron deficiency anemia and improving constitutions after long-term drinking.

The invention discloses a ferrous bisglycinate chelate nutritional composition and application thereof. The composition comprises the following active components in percentage by weight: 1.0-89.5% of ferrous bisglycinate chelate, 0.5-20.6% of active polypeptide, 0.4-21.0% of oligosaccharide and 4.0-89.5% of grease. Compared with the compound preparation merely using ferrous bisglycinate chelate and antioxidant, the absorption rate of the nutritional composition of the invention is improved by 20-30%; at the same time, the natural and healthy composition has good smell and good safety. In addition, the composition is rich in peptide and folic acid, thereby being beneficial to growing development for red blood cells. The ferrous bisglycinate chelate nutritional composition of the invention has the characteristics of stability, safety and high bioavailability and has obvious effect for preventing and improving iron-deficiency anemia.

The invention provides sialic acid-added milk powder with an easy digestion function for premature infants and a preparation method thereof, and relates to the technical field of foods. The milk powder is prepared from the following raw materials: skim milk powder, lecithin, maltodextrin, immune globulin, refined palm olein, vitamin complex, prebiotics, minerals, alpha-whey protein, lactotransferrin, ferrous gluconate, bifidobacterium, sialic acid, edible vegetable oil mixture, beta-galactosidase, tryptophan, threonine and cystine. Compositions of the formula of the milk powder for premature infants is closer to breast milk, memory and intelligence level of premature infants can be improved by the sialic acid ingredient added into the milk powder, and nutrition essential to premature infant growth can be provided by optimizing the proportion of ingredients. The milk powder can be easily digested and absorbed, and can be used for improving the resistance of premature infants and reducing the phenomena of internal heat and iron-deficiency anemia caused by dyspepsia.

The invention discloses a method for preparing super-micro molecular iron dextran by using super-micro molecular dextran (a weight-average molecular weight being 3,000-6,000Da) as a raw material. After the super-micro molecular dextran is subjected to oxidation, complexing, desalting, concentration preparation, filtration and encapsulation sterilization, an iron dextran injection product with an iron content of 25-250 mg / ml can be obtained, and the super-micro molecular iron dextran can be used for preventing and treating the iron-deficiency anemia of piglets and livestocks. According to the method for preparing the super-micro molecular iron dextran, a conventional potassium cyanide method and an alkali method are replaced by adopting oxydol / aqueous alkali oxidation, and a sodium hypochlorite method is improved; an alcohol precipitation method is replaced by using an electric dialyser method to remove the sodium chloride in iron dextran solution; simultaneously, the impurity removal working procedure of an intermediate product is further omitted; the production cost is decreased; the energy consumption is decreased; the production period is shortened; the toxicity is decreased; the emission of waste gas, waste water and industrial residues is reduced; the environmental pollution is reduced; and the production potential safety hazard caused by the usage of flammable and explosive alcohol is eliminated.

A Chinese medicine for supplementing Fe, nourishing blood and treating iron-deficiency anemia is prepared from 7 Chinese-medicinal materials including apatholobus stem, astragalus root, jujube, Chinese angelica root, etc. Its preparing process is also disclosed.

The invention relates to an Chinese medicinal oral liquid for treating iron-deficiency anemia, which is prepared from prepared fleece flower root, Chinese angelica root, astragalus root each 20-30g, pilose asiabell root, schisandra fruit, smoked plum, dried orange peel, poria cocos, radix salvia miltiorrhiza each 15-20g, prepared rhizome of rehmannia, wolfberry fruit each 10-15g and licorice root 10g.

The invention discloses a preparation method for a sanguinolaria blood-enriching product. The blood-enriching product is produced by using abundant heme iron in sanguinolaria; aimed targets are iron-deficiency anemia patients; the products comprise blood-enriching oral solutions, blood-enriching capsules, blood-enriching granules, blood-enriching electuaries, blood-enriching tablets and the like; further processing is carried out so that the problems of an existing method for eating the sanguinolaria that damages to a human body are great, heavy metal exceeds the standards, and deep processing is lacked are solved well. The sanguinolaria blood-enriching product has a good blood-enriching effect; the absorption utilization is up to be more than 25%; the safety of the blood-enriching product is higher than that of a blood-enriching preparation prepared from terrestrial animal blood; the sanguinolaria can remove a large part of shell toxins and the internal heavy metal in a temporary rearing process; a biological enzymolysis process is used for degrading macromolecular proteins in the sanguinolaria into micro-molecular protein peptides which are easily absorbed by a human body; beta-cyclodextrine is added into enzymatic hydrolysate so that the fishy smell and the bitter taste of the sanguinolaria enzymatic hydrolysate can be buried, and consumers can commonly accept the product.

The invention discloses a donkey-hide glue soft sweet. The formula is that the donkey-hide glue soft sweet contains the following ingredients by weight percent: 43.5 of white granulated sugar, 43.5 of starch syrup, 11.1 of modified starch, 0.05 of spice and 1.85 of particle donkey-hide glue. The production processes of the donkey-hide glue soft sweet comprise sugar cooking, depositing, drying, sanding and drying. The donkey-hide glue soft sweet is of the color of black tea and is transparent, has the functions of nourishing vital spirit, enriching blood, improving immunity and preventing osteoporosis, is suitable for people suffering from iron-deficiency anemia and post-hemorrhagic anemia, and has good regulation action on the body constitution of people who are old, weak, sick for long time, are apt to catch a cold and the like.

The invention discloses a drug combination as iron supplementary agent, which is characterized in that the drug combination comprises carbonyl iron, and natural anti-oxidant components with drug activity; the drug combination can also have pharmaceutical carrier. The invention also discloses the preparation comprising the drug combination, the preparation methods of the combination and the preparation, and the function of preventing and curing iron deficiency of the drug combination. The drug combination has the advantages that the iron deficiency anemia is treated effectively; the production of free radical in human body is inhibited; the oxygen metabolism balance in human body is maintained; the physical quality of the patient is enhanced; and the immunity of body is improved.