45 results about "Iron dextran" patented technology

The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium; and at least one component selected from the group comprising a vitamin, a vaccine, a growth stimulant, a dewormer, iron dextran, an antibiotic and a synchronization preparation. The synchronization preparation is a combination of injectable hormonal preparations, inplantable hormonal preparations, intravaginal hormonal preparation and other slow release hormonal preparation. The antibiotics include oral, injectable and implantable theurapeutic remedies. The vaccine includes antigens and a combination of antigens and adjuvents. The growth stimulants include zeranol, estradiol, testosterone, progesterone and trenbolone acetate. The dewormer includes macrocydic lactones, leramizoles, benzimidazoles and salicylanilides. The macrocydic lactones include doramectin, ivermectin, abamectin and moxidectin.

In a process for producing an iron-dextran compound for use in parenteral treatment of iron-deficiency in humans or animals a stable compound of desired relatively low molecular weight is obtained by using first hydrogenation and then oxidation to convert reducing terminal groups on the dextran molecules before reaction with the iron. By varying the ratio of hydrogenated groups to oxygenated groups the average molecular weight of the resulting iron-dextran compound can be varied.

The invention relates to an iron dextran raw material for human intravenous injection and a preparation method thereof. The iron dextran for human intravenous injection is prepared from dextran through hydrolysis, ultra-filtration or gel column separation, oxidation, complexing, ultra-filtration refining and ethanol precipitation or spray drying. For human injection, the dextran is pretreated after hydrolysis, the small molecular dextran of which the absolute molecular weight is 5000-8000 is prepared by separation with an ultra-filtration device or a gel column, an oxidant and an oxidation process are adjusted, sodium peroxycarbonate is used as the oxidant for oxidation, a final product is refined by separation with the ultra-filtration device or the gel column, and then the iron dextran raw material which has the weight-average molecular weight of 135000-190000 and the molecular weight distribution of less than 2.0 and can meet the human intravenous injection is obtained.

The invention discloses a compound iron-dextrin injection and a preparation method thereof. The injection is prepared from iron-dextrin, butafosfan and injection water. The preparation method comprises the following steps: (1) putting the prescribed butafosfan in a container, and adding a proper amount of injection water until the butafosfan is completely dissolved, regulating the pH to be 5.5-6.0 with a NaOH solution to obtain a butafosfan solution for later use; (2) adding a prescribed iron-dextrin solution into the butafosfan solution, uniformly mixing, and fixing the volume to the prescription with the injection water, sufficiently and uniformly mixing to obtain a mixed liquid; and (3) filtering and subpackaging the mixed liquid, filling, and sterilizing to obtain the compound iron-dextrin injection. The compound iron-dextrin injection can be used for preventing and treating secondary infection and other diseases caused by piglet anemia and low immunity, and promoting metabolism and stress resistance of piglets, so that the immunity of piglets can be strengthened, the energy utilization can be improved, and the slaughter weight of piglets can be increased.

The invention discloses iron dextran compound oral liquid which is prepared from the following raw materials: 20-40kg of iron dextran, 1-5kg of donkey-hide gelatin, 5-13kg of taurine, 10-50kg of sucrose, 0.35kg of benzoic acid and a proper amount of purified water. The invention also provides a preparation technology of the iron dextran compound oral liquid, which comprises the steps of (A) fetching the purified water, adding the donkey-hide gelatin of the formula dosage, and standing until the donkey-hide gelatin is completely dissolved; (B) fetching the purified water, adding the taurine of the formula dosage, and completely dissolving the taurine; (C) fetching the iron dextran of the formula dosage and the mixed liquid in the step (B), sequentially adding into the prepared mixed liquid in the step (A), and mixing uniformly. The oral liquid disclosed by the invention is widely applied to the iron-deficiency anemia caused by chronic blood loss, malnutrition, developmental phase and the like, and also can be used as an adjuvant therapy for anemia diseases of operation recovery, the liver and kidney, the heart, the skin and the like.

A preparation process of iron-dextrin particles. The raw materials contain 250 grams of iron-dextrin, 12000 grams of lactose and 7000 grams of starch, 50 grams of povidone K30 and 25 grams of aspartame. The preparation process comprises the steps of: sieving iron-dextrin, lactose, maltodextrin, povidone K30 and aspartame respectively through a 80 mesh sieve for standby; weighing accessories and the main drug according to the prescription, and uniformly mixing; Adding an adhesive for prepare a soft material; granulating by a 16 mesh sieve; drying at 60 DEG C; finishing the grains by a 12 mesh sieve; determining particle content; determine a bag weight; and packaging. A traditional preparation process of iron-dextrin particles requires particle preparation and tabletting, has long production cycle and high production cost; and the process of the invention can directly prepare the particles, does not need tabletting, and has shortened production cycle and simple process. The additional flavoring agent improves the taste, and improves the patient medication compliance in order to meet the needs of medical treatment.

The invention discloses a production method of an iron dextran product capable of being rapidly disintegrated in oral cavities of pigs and relates to the technical field of pig breeding. The production method comprises the following steps: step 1, preparing a medicament: taking iron dextran as a main material and adding auxiliary materials to prepare an inner-core layer mixture solution for lateruse; taking pre-gelatinized starch and jujube powder as raw materials; adding auxiliary materials and water, and uniformly stirring to obtain an outer-layer covering solution for later use; preparingNaCl and CaCl2 into a mixed solution with the concentration of 1 to 5 weight percent and taking the mixed solution as a receiving solution for later use; step 2, covering and preparing: preparing a medicine solution prepared by step 1 into the granular iron dextran product by utilizing a medicine covering instrument. According to the production method disclosed by the invention, the iron dextran product is prepared by covering is used for oral administration and is directly put into the oral cavities of the pigs to carry out patching; the problem that the pigs easily have stress response in anexisting injection process is solved; meanwhile, iron is supplemented through the oral administration, and time and labor are saved.