45 results about "Iron dextran" patented technology

In a process for producing an iron-dextran compound for use in parenteral treatment of iron-deficiency in humans or animals a stable compound of desired relatively low molecular weight is obtained by using first hydrogenation and then oxidation to convert reducing terminal groups on the dextran molecules before reaction with the iron. By varying the ratio of hydrogenated groups to oxygenated groups the average molecular weight of the resulting iron-dextran compound can be varied.

The invention discloses a compound iron-dextrin injection and a preparation method thereof. The injection is prepared from iron-dextrin, butafosfan and injection water. The preparation method comprises the following steps: (1) putting the prescribed butafosfan in a container, and adding a proper amount of injection water until the butafosfan is completely dissolved, regulating the pH to be 5.5-6.0 with a NaOH solution to obtain a butafosfan solution for later use; (2) adding a prescribed iron-dextrin solution into the butafosfan solution, uniformly mixing, and fixing the volume to the prescription with the injection water, sufficiently and uniformly mixing to obtain a mixed liquid; and (3) filtering and subpackaging the mixed liquid, filling, and sterilizing to obtain the compound iron-dextrin injection. The compound iron-dextrin injection can be used for preventing and treating secondary infection and other diseases caused by piglet anemia and low immunity, and promoting metabolism and stress resistance of piglets, so that the immunity of piglets can be strengthened, the energy utilization can be improved, and the slaughter weight of piglets can be increased.

A preparation process of iron-dextrin particles. The raw materials contain 250 grams of iron-dextrin, 12000 grams of lactose and 7000 grams of starch, 50 grams of povidone K30 and 25 grams of aspartame. The preparation process comprises the steps of: sieving iron-dextrin, lactose, maltodextrin, povidone K30 and aspartame respectively through a 80 mesh sieve for standby; weighing accessories and the main drug according to the prescription, and uniformly mixing; Adding an adhesive for prepare a soft material; granulating by a 16 mesh sieve; drying at 60 DEG C; finishing the grains by a 12 mesh sieve; determining particle content; determine a bag weight; and packaging. A traditional preparation process of iron-dextrin particles requires particle preparation and tabletting, has long production cycle and high production cost; and the process of the invention can directly prepare the particles, does not need tabletting, and has shortened production cycle and simple process. The additional flavoring agent improves the taste, and improves the patient medication compliance in order to meet the needs of medical treatment.

The invention discloses a production method of an iron dextran product capable of being rapidly disintegrated in oral cavities of pigs and relates to the technical field of pig breeding. The production method comprises the following steps: step 1, preparing a medicament: taking iron dextran as a main material and adding auxiliary materials to prepare an inner-core layer mixture solution for lateruse; taking pre-gelatinized starch and jujube powder as raw materials; adding auxiliary materials and water, and uniformly stirring to obtain an outer-layer covering solution for later use; preparingNaCl and CaCl2 into a mixed solution with the concentration of 1 to 5 weight percent and taking the mixed solution as a receiving solution for later use; step 2, covering and preparing: preparing a medicine solution prepared by step 1 into the granular iron dextran product by utilizing a medicine covering instrument. According to the production method disclosed by the invention, the iron dextran product is prepared by covering is used for oral administration and is directly put into the oral cavities of the pigs to carry out patching; the problem that the pigs easily have stress response in anexisting injection process is solved; meanwhile, iron is supplemented through the oral administration, and time and labor are saved.