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A kind of compound iron dextran injection and preparation method thereof

A technology of iron dextran injection, which is applied in the field of compound injection, and can solve problems such as weakened digestion and absorption function of piglets, iron deficiency anemia, and destruction of oxidation-reduction process

Active Publication Date: 2016-03-23
HENAN HUITONG TIANXIA BIO ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Taking piglets as an example, the total iron reserves of piglets at birth are 40-50 mg. For every 1 kg weight gain of suckling piglets, the iron requirement is about 35 mg, and the iron requirement is 7-8 mg / d. 200mg, while the iron content of breast milk is only 0.2mg / 100g, the daily iron intake of piglets from breast milk is less than 1 / 7 of the total requirement, which is far from meeting the needs of normal development of piglets. Days of age, the amount of iron stored in the body will be exhausted. If it cannot be replenished in time, iron deficiency anemia will easily occur, which will lead to the destruction of the redox process of the body, weaken the digestion and absorption function of the piglet, and reduce the body's resistance to cause secondary infection.
In addition, stress factors such as weaning and turning circles cause the growth performance of piglets to decline, and the weight of the weaned litter is small, which seriously affects the economic benefits of pig raising and has caused heavy losses to the pig raising industry.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The prescription of the compound iron dextran injection is: iron dextran, calculated as iron 5g, butafosfos 5g.

[0020] The preparation method of compound iron dextran injection is:

[0021] (1) Weigh 5 g of butafosfos into a container, then add an appropriate amount of water for injection to dissolve butafosfos; use NaOH solution to adjust the pH to 5.5-6.0 to obtain a butafosfos solution for later use.

[0022] (2) Weigh iron dextran, 5g is calculated as iron, that is, iron element is 5g, add it to butafosfos solution, mix well, then dilute to 100g with water for injection, mix well to obtain a mixed solution.

[0023] Or in this embodiment (2) weigh 25g of 20% iron dextran solution, wherein 20% iron dextran solution means that the mass concentration of Fe in the solution is 20%, add it to the butafosfos solution, mix well, and then inject Dilute to 100g with water, mix thoroughly to obtain a mixed solution.

[0024] (3) The mixed solution was filtered, subpackaged...

Embodiment 2

[0026] The prescription of compound iron dextran injection is: iron dextran, 7.5g in terms of iron, and 10g of butafosfos.

[0027] The preparation method of compound iron dextran injection is:

[0028] (1) Weigh 10 g of butafosfos into a container, then add an appropriate amount of water for injection to dissolve butafosfos; adjust the pH to 5.5-6.0 with NaOH solution to obtain a butafosfos solution.

[0029] (2) Weigh iron dextran, which is 7.5g in terms of iron, that is, 7.5g of iron element, add it to the butafosfos solution, mix well, then dilute to 100g with water for injection, mix well to obtain a mixed solution.

[0030] Or in the present embodiment (2) weigh 37.5g of 20% iron dextran solution, wherein 20% iron dextran solution means that the mass concentration of Fe in the solution is 20%, add it to the butafosfos solution, mix well, and use Dilute the water for injection to 100 g, and mix thoroughly to obtain a mixed solution.

[0031] (3) The mixed solution was f...

Embodiment 3

[0033] The prescription of the compound iron dextran injection is: iron dextran, 7.5 g in terms of iron, and 20 g of butafosf.

[0034] The preparation method of compound iron dextran injection is:

[0035] (1) Weigh 20 g of butafosfos into a container, then add an appropriate amount of water for injection to dissolve butafosfos; use NaOH solution to adjust the pH to 5.5-6.0 to obtain a butafosfos solution for later use.

[0036] (2) Weigh iron dextran, which is 7.5g in terms of iron, that is, the iron element is 7.5g, add it to the butafosfos solution, mix well, then dilute it to 100g with water for injection, and mix well to obtain a mixed solution .

[0037] Or in the present embodiment (2) weigh 37.5g of 20% iron dextran solution, wherein 20% iron dextran solution means that the mass concentration of Fe in the solution is 20%, add it to the butafosfos solution, mix well, and use Dilute the water for injection to 100 g, and mix thoroughly to obtain a mixed solution.

[0...

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PUM

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Abstract

The invention discloses a compound iron-dextrin injection and a preparation method thereof. The injection is prepared from iron-dextrin, butafosfan and injection water. The preparation method comprises the following steps: (1) putting the prescribed butafosfan in a container, and adding a proper amount of injection water until the butafosfan is completely dissolved, regulating the pH to be 5.5-6.0 with a NaOH solution to obtain a butafosfan solution for later use; (2) adding a prescribed iron-dextrin solution into the butafosfan solution, uniformly mixing, and fixing the volume to the prescription with the injection water, sufficiently and uniformly mixing to obtain a mixed liquid; and (3) filtering and subpackaging the mixed liquid, filling, and sterilizing to obtain the compound iron-dextrin injection. The compound iron-dextrin injection can be used for preventing and treating secondary infection and other diseases caused by piglet anemia and low immunity, and promoting metabolism and stress resistance of piglets, so that the immunity of piglets can be strengthened, the energy utilization can be improved, and the slaughter weight of piglets can be increased.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, and relates to a compound injection for preventing and treating comprehensive disorders caused by anemia of young animals, lack of trace elements, low resistance of animal bodies and the like. Background technique [0002] At present, there are outbreaks of major diseases in pig farms across the country. Almost all pig farms have been attacked by diseases such as PRRS, mycotoxins, circovirus, pseudorabies virus, and Haemophilus parasuis for a long time. Or the trend of sporadic infection, the probability of causing newborn young animals to be sick is also increasing day by day. In addition, due to reasons such as feeding management errors and untimely prevention, iron deficiency anemia and trace element deficiency in young animals, low animal body resistance and other reasons cause the body Functional disorders and other comprehensive disorders. [0003] Taking piglets as an example,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/721A61K9/08A61P7/06A61P37/04A61P3/02A61P3/14A61K31/662
Inventor 张要齐张新蕾孙雪峰
Owner HENAN HUITONG TIANXIA BIO ENG
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