Method of eliminating sodium chloride in iron-dextran complex compound water solution and device thereof

A technology of iron dextran and dextran, which is applied in the field of removing sodium chloride in an aqueous solution of iron dextran complexes and devices, can solve the problems of colloidal particle electrodialysis operation and high viscosity of materials, and achieve easy control, lower operating costs and The effect of energy consumption

Active Publication Date: 2008-01-23
GUANGXI RES INST OF CHEM IND CO LTD
View PDF2 Cites 28 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, there is no report on the desalination of high-solid, high-salt and high-viscosity polymer aqueous solutions by directly adopting the electrodialysis device finalized on the market, and the present invention solves th

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method of eliminating sodium chloride in iron-dextran complex compound water solution and device thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026]In the raw material circulation storage tank, the brine circulation storage tank, and the electrode liquid circulation storage tank, respectively add 40% of an aqueous solution of iron dextran complex with a salt content of 15% (w / w, the same below) and an iron content of 50 mg / mL. liter, 0.5% sodium chloride solution, 0.5% sodium sulfate solution, wherein the amount of sodium chloride solution and sodium sulfate solution is advisable to meet the cycle of electrodialysis process. Start the material liquid circulation pump, and after the material circulation is stable, apply direct current until the current density is 50mA / cm 2 , keep the voltage constant, and carry out constant voltage electrodialysis. During the electrodialysis process, distilled water was continuously added to maintain the iron dextran solution volume at 40 liters. During the electrodialysis process, the solution temperature was controlled at 15°C. Along with the carrying out of electrodialysis proces...

Embodiment 2

[0028] Add 80kg of iron dextran solution with iron content ≥ 50mg / mL and 15% salt content, 0.5% sodium chloride solution, and 0.5% sulfuric acid in the raw material circulation storage tank, brine circulation storage tank, and electrode solution circulation storage tank. Sodium solution, wherein the amount of sodium chloride solution and sodium sulfate solution is advisable to meet the electrodialysis process cycle. Start the material liquid circulation pump, and after the material circulation is stable, apply direct current until the current density is 55mA / cm 2 , keep the voltage constant, carry out constant voltage electrodialysis and control the solution temperature to 55°C. Along with the carrying out of electrodialysis process, electric current constantly drops, and when energizing amount reaches 5497 ampere hours, stops electrodialysis, discharges, and obtains sodium chloride content and is less than 1.0%, and iron content is greater than 45kg of dextran iron solution o...

Embodiment 3

[0030] Add 130kg of iron dextran solution with iron content ≥ 50mg / mL and 15% salt content, 0.5% sodium chloride solution, and 0.5% sulfuric acid in the raw material circulation storage tank, brine circulation storage tank, and electrode solution circulation storage tank. Sodium solution, wherein the amount of sodium chloride solution and sodium sulfate solution is advisable to meet the electrodialysis process cycle. Start the material liquid circulation pump, and after the material circulation is stable, apply direct current until the current density is 55mA / cm 2 , keep the voltage constant, carry out constant voltage electrodialysis and control the solution temperature not higher than 90°C. Along with the carrying out of electrodialysis process, electric current constantly drops, and when energizing amount reaches 8932 ampere hours, stops electrodialysis, discharges, and obtains sodium chloride content and is less than 2.0%, and iron content is greater than 43kg of iron dext...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a method and device for eliminating sodium chloride in the aqueous solution for the complex of ferrodextran, which is characterized in that: the ferrodextran is prepared with dextran and ferric trichloride. The sodium chloride in the ferrodextran is eliminated with an electrodialysis film, that is, eliminating the sodium chloride of the solvent by electrodialysis process in the ferrodextran complex solvent with iron content is more than or equal to 40mg/ml, sodium chloride content is more than or equal to 5.0 per cent wt and viscosity of 3.0mpa is multiplied by s (20 DEG C.) under the temperature of 10 to 90 DEG C. Compared with the technique of eliminating sodium chloride with alcohol precipitation, the invention prevents the safety hazard from flammable and combustible alcohol and reduces the production cost.

Description

technical field [0001] The invention relates to a method and device for removing impurities in the process of producing iron dextran complex, in particular to a method and device for removing sodium chloride in an aqueous solution of iron dextran complex. Background technique [0002] Iron dextran is an iron supplement for humans and animals. Iron dextran can be used to treat iron deficiency anemia in humans or animals by oral or injection. Iron dextran is a macromolecular complex, which is obtained by degrading dextran (weight average molecular weight about 20,000) under alkaline conditions, then neutralizing it with acid, and performing a complex reaction with ferric chloride. The stock solution of iron dextran complex contains a large amount of inorganic salt-sodium chloride, and its weight percentage is generally greater than 10%. The iron dextran injection requires that the iron dextran solution sodium chloride has a weight percent concentration of less than 2%, so the...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K31/721A61P3/02C08B37/00B01D61/48
Inventor 翁德洪李广梁艳玲韦少平柯敏韦宏张丽娟
Owner GUANGXI RES INST OF CHEM IND CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap