6 results about "Salicylanilide" patented technology

The invention discloses a 2-hydroxy-benzonitril solution and a production method thereof, the production method comprises the step of preparing a wet 2-hydroxy-benzonitril product through reaction of salicylamide and phosgene, and is characterized in that the wet 2-hydroxy-benzonitril product is directly added into a sodium hydroxide aqueous solution to obtain the 2-hydroxy-benzonitril solution. The sodium salt solution can be directly produced without taking out the 2-hydroxy-benzonitril, so that exposure of the 2-hydroxy-benzonitril is avoided, personal injury is reduced, investment of drying equipment is reduced, and direct feeding of downstream products is facilitated.

The invention belongs to the technical field of pigment wastewater treatment, and particularly provides a low-excess-sludge pigment wastewater treatment process which comprises the following steps: 1) performing coagulating sedimentation and micro-electrolysis treatment on to-be-treated wastewater to remove suspended solids and toxic substances to obtain pretreated wastewater; (2) the pretreated wastewater is treated through a biochemical unit, the biochemical unit treatment comprises hydrolytic acidification and two-stage biological contact oxidation, and biological membrane filler is loaded and salicylanilide derivatives are added in the biological contact oxidation treatment process.The treatment process has the advantages of being high in COD treatment efficiency and low in residual sludge amount.

The current invention is in the field of molecular biology / pharmacology and provides methods of using a pharmaceutical composition of 5-(2′,4′-difluorophenyl)-salicylanilide derivatives and their ring-fused analogs for inhibiting, reducing, or treating chronic kidney disease or / and renal fibrosis, conditions leading to or arising from it, and / or negative effects of each thereof.

The invention discloses alkyl polyether oxidized salicylanilide, a preparation method of the alkyl polyether oxidized salicylanilide, an imbibition agent composition, an oil-displacing agent and application of the oil-displacing agent. The structural formula of the alkyl polyether oxidized salicylanilide is shown in the formula (I). In the formula (I), R is a polyether group. The alkyl polyether oxidized salicylanilide disclosed by the invention is used as an imbibition agent component and has super-strong interface wetting change performance. By using the alkyl polyether oxidized salicylanilide, the imbibition efficiency in oil reservoirs, especially in the field of oil displacement recovery of low-permeability, ultra-low-permeability, ultra-low-permeability and unconventional tight oil reservoirs, is improved, so that the recovery efficiency of the oil reservoirs is improved, and the alkyl polyether oxidized salicylanilide has extremely high economic value. The imbibition agent adopting the alkyl polyether oxidized salicylanilide disclosed by the invention has good high temperature resistance and high salt resistance.

The invention belongs to the technical field of chemical production, and provides a 2-hydroxy-benzonitrile by-product recovery process which is characterized by comprising the following steps: step 1, cooling and condensing a liquid-phase crude product from a 2-hydroxy-benzonitrile synthesis reactor, then adding a sodium hydroxide solution, adjusting the pH value, stirring for 0.5-1 hour, standing for layering, and separating a water phase; step 2, dropwise adding hydrochloric acid into the water phase, adjusting the pH value, cooling to 8-10 DEG C, separating out crystals, and filtering to obtain crude phenol; and step 3, heating the crude phenol to 60-70 DEG C for melting, adding activated carbon and sodium hydrogen sulfite, stirring for 20-30 minutes, filtering while hot, and rectifying to obtain phenol. According to the method disclosed by the invention, through the synergistic effect of the process steps, high-efficiency and high-purity recovery of phenol in the 2-hydroxy-benzonitril process is realized on the premise of not introducing an organic extraction agent, the production cost is remarkably reduced, and the method has a remarkable industrial application value.

The application discloses a kind of high content salicylanilide research and development extraction devices, including extraction kettle, setting in the upper end one side of extraction kettle import and setting in the bottom end of extraction kettle drain port;The top of the extraction kettle is provided with first protective cover, the inside of the first protective cover is provided with spraying mechanism, the spraying mechanism includes annular groove body being set in the inside of first protective cover and the top opening, the inside of the annular groove body is provided with baffle, the upper end of the baffle is provided with rotary disc.The high content salicylanilide research and development extraction device, by setting annular groove body, second motor, rotary disc, push block, displacement block, movable rod, connecting seat, connecting plate, guide slot, first spring, guide pulley cooperation branch pipe, water pipe can be realized to the inner wall of extraction kettle and wash, water pipe one end is connected with clean water source, spray head can constantly adjust inclination, to wash the upper end and lower end of the inner wall of extraction kettle, improve efficiency.