The invention discloses a chemical production method, in particular a novel green production process for propylene oxide. In the method, the process design is carried out by using bipolar membrane, electrodialysis, antiosmosis, air flotation, heat exchange, oxidation, and other technology. In the production process, sodium hydroxide replaces the conventional calcium hydroxide and generates sodium chloride through reaction; the sodium chloride generates hydrochloric acid and sodium hydroxide by the bipolar membrane technology; and the hydrochloric acid is recovered, and the sodium hydroxide and water can be recycled. Therefore, no new sodium hydroxide is needed and no wastewater is discharged in the production of the propylene oxide. The sodium hydroxide is added at the preliminary stage of the production of the propylene oxide, and the input amount of the sodium hydroxide is controlled between 5 and 15 percent. The novel green production process for the propylene oxide has the advantages that: the recycling of the water, sodium chloride and sodium hydroxide is realized, the effects of zero discharge and input reduction of production materials are substantially achieved, and finally better social and economic benefits are achieved. The novel green production process for the propylene oxide can be widely applied to the chlorohydrin production in China.