3 results about "Low molecular weight dextran" patented technology

The invention relates to the technical field of edible mushroom processing, in particular to low-molecular-weight hericium erinaceus beta-glucan with antioxidant activity as well as a preparation method and application of the low-molecular-weight hericium erinaceus beta-glucan. According to the method, the macromolecular hericium erinaceus beta-glucan is used as a raw material, the low-molecular-weight beta-glucan is prepared through microwave digestion and compound enzyme step-by-step degradation, the weight-average molecular weight of the prepared low-molecular-weight beta-glucan is 7.611 kDa, and compared with a high-molecular-weight beta-glucan sample, the low-molecular-weight beta-glucan is better in water solubility and lower in solution viscosity; the compound has the capability of efficiently scavenging free radicals, has good antioxidant activity, and has a wide application prospect.

This invention relates to the field of animal reproductive regulation technology, and discloses a twinning regulator for sika deer males that synchronize estrus and its application method. The regulator is a homogeneous and transparent sol system prepared from trehalose, pituitary follicle-stimulating hormone (FSH), medium- and low molecular weight sodium hyaluronate, low molecular weight dextran sulfate, zinc gluconate, and physiological saline. This invention utilizes sodium hyaluronate of a specific molecular weight and dextran sulfate to construct a polysaccharide sol network, combined with the cross-linking effect of zinc gluconate and the physicochemical stabilizing effect of trehalose, to encapsulate and slowly release FSH. The application method includes implanting and removing a vaginal silicone plug, combined with the injection of pregnant mare serum gonadotropin (PMSG) and the regulator, followed by natural mating. This invention prolongs the half-life of exogenous hormones in the animal, avoids drastic fluctuations in blood drug concentration, and improves the stability of twinning rates in sika deer.

The application discloses use of a low molecular weight dextran sulfate derivative in preparation of an anticoagulant drug, the low molecular weight dextran sulfate derivative is shown as formula (I), wherein a main connection mode is an alpha-(1, 6)-glycosidic bond main chain, relates to a weight average molecular weight (M w )≤40 kDa, and each glucose unit has at least 1.0-2.0 sulfate groups on average, wherein the low molecular weight dextran sulfate derivative has a high selective inhibitory activity on a blood coagulation factor X enzyme, so as to inhibit an endogenous blood coagulation pathway; can effectively inhibit thrombosis in vivo and in vitro, and has potential as a novel endogenous anticoagulant.