7results about How to "Good resolubility" patented technology

The invention discloses an epoxy modified room-temperature self-crosslinking water-based acrylate dispersion as well as a preparation method and application thereof, and belongs to the field of water-based acrylic resin. The dispersoid is obtained by extracting an organic solvent from an acrylate polymer, adjusting the pH value to 7.5-8.5, mixing with ionized water and binary hydrazide, dispersing and filtering. The acrylate polymer is obtained by carrying out solution polymerization on a mixed solution of a part of initiator, a hard monomer, a soft monomer, a first type of hydrophilic monomer, a second type of hydrophilic monomer, epoxy resin and a combined cross-linking monomer and a residual initiator dissolved in an organic solvent at 80-83 DEG C, wherein the mixed solution is prepared from the initiator, the hard monomer, the soft monomer, the first type of hydrophilic monomer, the second type of hydrophilic monomer, epoxy resin and the combined cross-linking monomer. The main solvent of the dispersion is water, the viscosity is low, and the content of the organic solvent is 1t; the water-based ink has the advantages of low content of VOCs (volatile organic compounds), multiple cross-linked network structure, high cross-linking degree (78-83%), excellent resolubility after being prepared into ink, good adhesive force on a plastic film, good water resistance, good storage stability and high glossiness.

The invention discloses a preparation method of stability-enhanced alginic acid-keratin-based double-coated nanoparticles. The preparation method comprises the following steps: carrying out controllable enzymolysis, enzyme deactivation, centrifugation and freeze-drying on keratin to obtain keratin nanoparticles formed by self-assembly; dispersing the keratin nanoparticles in an acidic buffer solution to carry out structure development, adding bioactive molecules, and adjusting the pH to be neutral to recombine and close the keratin nanoparticle structure to obtain a keratin nanoparticle solution loaded with the bioactive molecules; the preparation method comprises the following steps: taking keratin as a template, dispersing the keratin into a sodium alginate solution, dropwise adding into a calcium chloride solution, cross-linking to form a calcium alginate shell, dialyzing or centrifuging to remove free bioactive molecules, and freeze-drying to obtain the bioactive molecule loaded alginic acid-keratin-based double-coated nanoparticles. The invention also discloses double-coated nanoparticles and application thereof, through controllable enzymolysis and pH regulation and control, the self-assembly and bioactive molecule encapsulation of the keratin nanoparticles are improved, and the double-coated nanoparticles with regular shape, good dispersibility, good redissolvability and good environmental stability are formed.

The application discloses a vaccine heat-resistant protective agent, a preparation method and application thereof, and belongs to the technical field of vaccines. The vaccine heat-resistant protective agent comprises the following raw materials: polycarboxybetaine, taurine, a sugar substance, polysarcosine, erythritol, gelatin enzymatic hydrolysate, a metal ion chelating agent and a buffer. The application also provides a preparation method. Compared with the prior art, the synergistic effect of polycarboxybetaine, taurine, a sugar substance, polysarcosine, gelatin enzymatic hydrolysate, erythritol and EDTA-Na2 can significantly improve the freeze-dried cake forming and reconstitution performance, shorten the reconstitution time, reduce the turbidity and insoluble particles. After 2-8 DEG C, 25 DEG C and 37 DEG C storage and multiple freeze-thaw cycle investigations, the antigen content residual rate and glass transition temperature are obviously superior to those of a traditional sucrose and mannitol system, and the inactivation risk caused by cold chain fluctuation can be effectively buffered.

The present application relates to the technical field of collagen, in particular to a kind of active collagen lyophilized preparation and its preparation method and application.The preparation method includes the following steps: S1, the aqueous solution of freeze-drying protective agent is prepared;S2, the initial emulsion of active collagen is diluted with physiological saline, to obtain the first solution, then mixed with the aqueous solution obtained in step S1, to obtain the second solution;S3, the second solution obtained in step S2 is added to the aqueous solution of step S1, and the third solution is prepared after mixing and emulsifying, to obtain mixed emulsion;S4, the mixed emulsion in step S3 is filled and freeze-dried, wherein the freeze-drying protective agent includes glycine, and the concentration of active collagen in the third solution is 5-15 mg / mL.The lyophilized preparation prepared by the preparation method has excellent reconstitution effect, and is convenient for transportation and storage.

The invention discloses a vacuum aluminizing water-based coating liquid for paper printing. The coating liquid comprises a low-Tg / high-hardness water-based acrylic emulsion and a polycarbonate type and / or acrylic acid modified water-based polyurethane dispersion which are used as film-forming materials, and is matched with substances such as a water-based auxiliary agent, a film-forming auxiliary agent, a wax emulsion and water. The low-Tg / high-hardness water-based acrylic emulsion is a styrene-acrylic emulsion with a core-shell structure, which is synthesized by adopting alkali-soluble acrylate solid resin under specific selection as a reactive macromolecular rheology control emulsifier and adopting a seeded emulsion polymerization method. The coating liquid disclosed by the invention has excellent rheological property, excellent sealing property and film-forming property, ultrahigh aluminizing gloss and wear resistance, excellent anti-sticking and anti-light-reversing property, chemical resistance, redissolving property, printing adaptability and environmental protection property, and is suitable for various printing and coating modes; the printing ink is especially suitable for the printing industries of tobacco, wine and the like which have extremely strict requirements on printing speed, drying speed, wear resistance, sticking resistance and aluminized appearance.

The invention provides a creatine kinase isoenzyme freeze-dried product as well as a preparation method and application thereof. The creatine kinase isoenzyme freeze-dried product is prepared from the following raw materials: a creatine kinase isoenzyme antigen, polygonatum polysaccharide and a chelating agent; the chelating agent comprises any one of citric acid, iminodiacetic acid and 1-hydroxyethylidene-1, 1-diphosphonic acid. The components such as the polygonatum polysaccharide and the chelating agent are adopted, so that double protection of oxidation resistance and dimer stability is realized, and the creatine kinase isoenzyme is good in activity after freeze-drying, stable in long-term storage and good in detection accuracy and repeatability.