Pantoprazole sodium freeze-dried powder injection and preparing method thereof

A technology for freeze-dried powder injection and pantoprazole sodium, which is applied in the field of pharmaceutical preparations, can solve the problems of unknown side effects, affect patient safety, etc., and achieves the effects of simple formula, good redissolvability and good quality
CN101229138AActive Publication Date: 2008-07-30SHANDONG LUOXIN PARMACEUTICAL GROUP STOCK CO LTD +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANDONG LUOXIN PARMACEUTICAL GROUP STOCK CO LTD
Publication Date
2008-07-30

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Abstract

The invention aims at providing a pantoprazole sodium freeze-dried powder injection and comprises pantoprazole sodium and mannitol with the weight ratio of 1: 2 to 5. The invention is simple in formula and little in side effect; products prepared by the method are plump in appearance, good in complex solubility and excellent in quality with the adoption of an advanced freezing and drying process.
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Description

technical field

[0001] The invention provides a pantoprazole sodium freeze-dried powder injection and a preparation method thereof, belonging to the field of pharmaceutical preparations. Background technique

[0002] Proton pump inhibitors are one of the most widely used basic drugs in the treatment of diseases related to abnormal gastric acid secretion in modern times. Pantoprazole sodium is a dialkylpyridylbenzimidazole compound, which is clinically used for duodenal ulcer and gastric ulcer , Zoe-Ellison syndrome, and relief of moderate to severe reflux esophagitis, its advantages are: high cure rate, fast cure speed, according to literature reports, this product has a 100% cure rate for duodenal and gastric ulcers in four weeks, and the cure rate is 100%. The rate and remission rate are all better than H2-receptor inhibitors, and the cure rate for reflux esophagitis is more than 80% in eight weeks.

[0003] The pharmacological mechanism and characteristics of pantoprazol...

Claims

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