The invention belongs to the technical field of membrane separation, and discloses a composite
nanofiltration membrane based on bidirectional
interfacial polymerization and a preparation method and application thereof, the preparation method comprises the following steps: step 1, loading two-dimensional
porous graphene on the upper surface of a porous support membrane to obtain a two-dimensional
porous graphene layer / support layer
composite membrane; 2, enabling the lower surface of the
composite membrane to be in contact with a water-phase amine
monomer solution, so that the water-phase solution infiltrates the supporting layer and is diffused upwards to the two-dimensional
porous graphene layer; 3, the upper surface of the two-dimensional porous
graphene layer makes contact with an organic phase
monomer solution, an aqueous phase amine
monomer and the organic phase monomer are subjected to an
interfacial polymerization reaction in in-plane pore channels of the two-dimensional porous
graphene, a porous
graphene /
polymer separation layer is formed, in-situ shrinkage and packaging of the in-plane pore channels of the two-dimensional porous graphene are achieved, and the composite
nanofiltration membrane is obtained. The composite
nanofiltration membrane provided by the invention has efficient interception and high
permeation flux on
antibiotics, and shows good application universality and flexibility.